MCID: SPL003
MIFTS: 19

Splenic Flexure Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Splenic Flexure Cancer

MalaCards integrated aliases for Splenic Flexure Cancer:

Name: Splenic Flexure Cancer 12 15
Malignant Neoplasm of Splenic Flexure of Colon 74
Malignant Neoplasm of Splenic Flexure 12
Malignant Tumor of Splenic Flexure 12
Ca Splenic Flexure - Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12191
ICD9CM 36 153.7
SNOMED-CT 69 94072004
ICD10 34 C18.5
UMLS 74 C0153440

Summaries for Splenic Flexure Cancer

MalaCards based summary : Splenic Flexure Cancer, also known as malignant neoplasm of splenic flexure of colon, is related to diverticulitis of colon and descending colon cancer. An important gene associated with Splenic Flexure Cancer is GLE1 (GLE1 RNA Export Mediator). Affiliated tissues include colon.

Related Diseases for Splenic Flexure Cancer

Diseases related to Splenic Flexure Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 diverticulitis of colon 9.6 DCXR STC1
2 descending colon cancer 9.3 DCXR EZR GLE1

Comorbidity relations with Splenic Flexure Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Colorectal Cancer
Deficiency Anemia Intestinal Obstruction
Paralytic Ileus

Symptoms & Phenotypes for Splenic Flexure Cancer

Drugs & Therapeutics for Splenic Flexure Cancer

Search Clinical Trials , NIH Clinical Center for Splenic Flexure Cancer

Genetic Tests for Splenic Flexure Cancer

Anatomical Context for Splenic Flexure Cancer

MalaCards organs/tissues related to Splenic Flexure Cancer:

42
Colon

Publications for Splenic Flexure Cancer

Articles related to Splenic Flexure Cancer:

# Title Authors Year
1
Is Segmental Colon Resection an Alternative Treatment for Splenic Flexure Cancer? ( 30950767 )
2019
2
How to do a laparoscopic high left colectomy with complete mesocolic excision and central vascular ligation for splenic flexure cancer. ( 30953397 )
2019
3
Intracorporeal versus extracorporeal anastomosis after laparoscopic left colectomy for splenic flexure cancer: results from a multi-institutional audit on 181 consecutive patients. ( 29344788 )
2018
4
Comparison of long-term outcomes after laparoscopic-assisted and open colectomy for splenic flexure cancer. ( 29745072 )
2018
5
How we do it: totally laparoscopic complete mesocolon excision for splenic flexure cancer. ( 30083837 )
2018
6
Iatrogenic diaphragmatic hernia following laparoscopic left colectomy for splenic flexure cancer An unusual complication. ( 28232645 )
2016
7
Laparoscopic colonic resection for splenic flexure cancer: our experience. ( 26148781 )
2015

Variations for Splenic Flexure Cancer

Expression for Splenic Flexure Cancer

Search GEO for disease gene expression data for Splenic Flexure Cancer.

Pathways for Splenic Flexure Cancer

GO Terms for Splenic Flexure Cancer

Cellular components related to Splenic Flexure Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 EZR GLE1 STC1
2 apical plasma membrane GO:0016324 9.16 EZR STC1
3 microvillus GO:0005902 8.96 DCXR EZR
4 brush border GO:0005903 8.62 DCXR EZR

Biological processes related to Splenic Flexure Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to cAMP GO:0071320 8.62 EZR STC1

Molecular functions related to Splenic Flexure Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 DCXR EZR GLE1

Sources for Splenic Flexure Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....