MCID: SPL008
MIFTS: 23

Splenic Tuberculosis

Categories: Infectious diseases

Aliases & Classifications for Splenic Tuberculosis

MalaCards integrated aliases for Splenic Tuberculosis:

Name: Splenic Tuberculosis 12 15
Tuberculosis, Splenic 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9305
ICD10 33 A18.85
ICD9CM 35 017.7
MeSH 44 D014400
SNOMED-CT 68 28399005
UMLS 73 C0041331

Summaries for Splenic Tuberculosis

Disease Ontology : 12 An abdominal tuberculosis that results in formation of granulomas or abscesses located in spleen.

MalaCards based summary : Splenic Tuberculosis, also known as tuberculosis, splenic, is related to pancreatic cancer and liver lymphoma. An important gene associated with Splenic Tuberculosis is SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include spleen and spleen, and related phenotype is neoplasm.

Related Diseases for Splenic Tuberculosis

Diseases related to Splenic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Related Disease Score Top Affiliating Genes
1 pancreatic cancer 27.3 CEACAM5 GRP KRT19
2 liver lymphoma 10.3 CEACAM5 SMUG1
3 gallbladder squamous cell carcinoma 10.3 CEACAM5 SMUG1
4 malignant spiradenoma 10.3 CEACAM5 SMUG1
5 tolosa-hunt syndrome 10.2 CEACAM5 SMUG1
6 gastric signet ring cell adenocarcinoma 10.2 CEACAM5 SMUG1
7 femoral neuropathy 10.2 CEACAM5 SMUG1
8 pericardial tuberculosis 10.2 CEACAM5 SMUG1
9 descending colon cancer 10.2 CEACAM5 SMUG1
10 prostate squamous cell carcinoma 10.2 CEACAM5 SMUG1
11 tuberculous peritonitis 10.2 CEACAM5 SMUG1
12 tuberculous empyema 10.2 CEACAM5 IL2
13 xanthogranulomatous cholecystitis 10.1 CEACAM5 SMUG1
14 hypersensitivity reaction type iv disease 10.1 IL2 SMUG1
15 female reproductive organ cancer 10.1 CEACAM5 SMUG1
16 rectal neoplasm 10.0 CEACAM5 SMUG1
17 endocrine gland cancer 10.0 CEACAM5 SMUG1
18 anal gland adenocarcinoma 9.8 CEACAM5 KRT19
19 anus adenocarcinoma 9.8 CEACAM5 KRT19
20 cutaneous adenocystic carcinoma 9.8 CEACAM5 KRT19
21 pericardium cancer 9.8 KRT19 SMUG1
22 thyroid carcinoma, familial medullary 9.8 CEACAM5 GRP
23 chondroid lipoma 9.8 CEACAM5 KRT19
24 cervical clear cell adenocarcinoma 9.8 CEACAM5 KRT19
25 pericardial mesothelioma 9.8 KRT19 SMUG1
26 biliary papillomatosis 9.8 CEACAM5 KRT19
27 superior mesenteric artery syndrome 9.8 CEACAM5 KRT19
28 immune system organ benign neoplasm 9.7 CEACAM5 KRT19
29 thymus lipoma 9.7 CEACAM5 KRT19
30 bile duct adenocarcinoma 9.7 CEACAM5 KRT19
31 polycystic liver disease 1 with or without kidney cysts 9.6 CEACAM5 KRT19
32 spondyloarthropathy 1 9.6
33 thrombocytopenic purpura, autoimmune 9.6
34 acute leukemia 9.6
35 crohn's disease 9.6
36 hemangioma 9.6
37 hepatitis 9.6
38 leukemia 9.6
39 neutropenia 9.6
40 lymphoma 9.6
41 choroiditis 9.6
42 pericarditis 9.6
43 splenic infarction 9.6
44 hemangioma of spleen 9.6
45 purpura 9.6
46 pancreatitis 9.6
47 hypersplenism 9.6
48 spondylitis 9.6
49 monoclonal gammopathy of uncertain significance 9.6
50 peritonitis 9.6

Graphical network of the top 20 diseases related to Splenic Tuberculosis:



Diseases related to Splenic Tuberculosis

Symptoms & Phenotypes for Splenic Tuberculosis

MGI Mouse Phenotypes related to Splenic Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 IL2 KRT19 SMUG1

Drugs & Therapeutics for Splenic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Splenic Tuberculosis

Cochrane evidence based reviews: tuberculosis, splenic

Genetic Tests for Splenic Tuberculosis

Anatomical Context for Splenic Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Splenic Tuberculosis:

19
Spleen

MalaCards organs/tissues related to Splenic Tuberculosis:

41
Spleen

Publications for Splenic Tuberculosis

Articles related to Splenic Tuberculosis:

(show top 50) (show all 56)
# Title Authors Year
1
Splenic tuberculosis. ( 29253708 )
2018
2
Isolated splenic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration. ( 28410696 )
2017
3
Splenic tuberculosis and multifocal serpiginoid choroiditis. ( 28798995 )
2017
4
Isolated splenic tuberculosis with subsequent paradoxical deterioration: a case report. ( 28438221 )
2017
5
Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report. ( 28357096 )
2017
6
Solitary splenic tuberculosis: a case report and review of the literature. ( 27250119 )
2016
7
Splenic Tuberculosis - Case Report. ( 27172532 )
2016
8
Splenic tuberculosis in a patient with newly diagnosed advanced HIV infection. ( 27635384 )
2016
9
Splenic tuberculosis in an immunocompetent patient can be managed conservatively: a case report. ( 26567167 )
2015
10
A Case of Splenic Tuberculosis Forming a Gastro-splenic Fistula. ( 26387701 )
2015
11
A case of isolated splenic tuberculosis. ( 25667987 )
2015
12
Isolated Splenic Tuberculosis without Any Radiological Focal Lesion. ( 25628658 )
2015
13
Isolated splenic tuberculosis in an immunocompetent patient. ( 24599429 )
2014
14
Splenic tuberculosis: a rare entity. ( 24414191 )
2014
15
Disseminated tuberculosis with splenic tuberculosis abscess rupture. A rare presentation. ( 25271747 )
2014
16
Inflammatory pseudotumour of the spleen associated with splenic tuberculosis. ( 25548610 )
2014
17
A rare presentation of splenic tuberculosis with a pseudocyst. ( 24825554 )
2014
18
Idiopathic thrombocytopenic purpura associated with splenic tuberculosis: case report. ( 23524902 )
2013
19
Splenic tuberculosis presenting as ascites in immunocompetant patient. ( 23634345 )
2013
20
Splenic tuberculosis presenting as fever of unknown origin with severe neutropenia. ( 23777575 )
2013
21
Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis. ( 24348671 )
2013
22
Splenic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration. ( 24949357 )
2012
23
Splenic tuberculosis. ( 23268618 )
2012
24
Splenic tuberculosis in a patient with ankylosing spondylitis treated with adalimumab. ( 22257918 )
2011
25
A 52-year-old Cuban immigrant with weight loss, dyspnea, and fever. Splenic tuberculosis. ( 21217183 )
2011
26
A case of mass-forming splenic tuberculosis: MRI findings with emphasis of diffusion-weighted imaging characteristics. ( 21394320 )
2011
27
Splenic tuberculosis in a patient with Crohn's disease on infliximab: case report. ( 19591134 )
2010
28
Isolated splenic tuberculosis: A case report. ( 21607149 )
2010
29
Splenic tuberculosis: a case report. ( 19119039 )
2009
30
Electronic clinical challenges and images in GI. Splenic tuberculosis mimicking splenic infarction. ( 19059251 )
2009
31
Splenic tuberculosis associated with monoclonal gammopathy of undetermined significance and pericarditis. ( 19652238 )
2009
32
Isolated splenic tuberculosis presenting with splenomegaly and pyrexia of unknown origin. ( 18366419 )
2008
33
Pancreatic tuberculosis with splenic tuberculosis mimicking advanced pancreatic cancer with splenic metastasizes: a case report. ( 18694521 )
2008
34
Splenic tuberculosis presenting as pyrexia of unknown origin. ( 17682577 )
2007
35
Radiological manifestations of splenic tuberculosis: a 23-patient case series from India. ( 17642503 )
2007
36
Magnetic resonance imaging for multiple macronodular localized splenic tuberculosis. ( 17320782 )
2007
37
Case report of lymph nodal, hepatic and splenic tuberculosis in an HIV-positive patient. ( 16878268 )
2006
38
Laparoscopic diagnosis of splenic tuberculosis. ( 17057582 )
2006
39
Isolated splenic tuberculosis. ( 15712554 )
2005
40
Splenic tuberculosis and HIV-1 infection. ( 11830228 )
2002
41
Splenic tuberculosis presenting as hypersplenism. ( 11284254 )
2001
42
Isolated splenic tuberculosis. ( 11552484 )
2001
43
Isolated splenic tuberculosis presenting with pyrexia of unknown origin. ( 11200387 )
2000
44
Possible splenic tuberculosis presenting as unexplained fever. ( 11192535 )
2000
45
Splenic tuberculosis: an unusual sonographic presentation. ( 10563082 )
1999
46
Primary splenic tuberculosis in a patient with nasal angiocentric lymphoma: mimicking metastatic tumor on abdominal CT. ( 10405243 )
1999
47
Splenic tuberculosis. ( 10621896 )
1999
48
Splenic tuberculosis--a case report. ( 10063303 )
1998
49
CT findings in splenic tuberculosis. ( 9640876 )
1998
50
Splenic tuberculosis in patients with fever of unknown origin. ( 17265622 )
1997

Variations for Splenic Tuberculosis

Expression for Splenic Tuberculosis

Search GEO for disease gene expression data for Splenic Tuberculosis.

Pathways for Splenic Tuberculosis

Pathways related to Splenic Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.69 CEACAM5 IL2

GO Terms for Splenic Tuberculosis

Sources for Splenic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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