MCID: SPL008
MIFTS: 30

Splenic Tuberculosis

Categories: Immune diseases, Infectious diseases

Aliases & Classifications for Splenic Tuberculosis

MalaCards integrated aliases for Splenic Tuberculosis:

Name: Splenic Tuberculosis 12 15 17
Tuberculosis, Splenic 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:9305
ICD9CM 34 017.7
MeSH 44 D014400
SNOMED-CT 67 28399005
ICD10 32 A18.85
UMLS 70 C0041331

Summaries for Splenic Tuberculosis

Disease Ontology : 12 An abdominal tuberculosis that results in formation of granulomas or abscesses located in spleen.

MalaCards based summary : Splenic Tuberculosis, also known as tuberculosis, splenic, is related to hypersplenism and miliary tuberculosis. An important gene associated with Splenic Tuberculosis is GRP (Gastrin Releasing Peptide), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Folate Metabolism. Affiliated tissues include spleen, bone marrow and colon.

Related Diseases for Splenic Tuberculosis

Diseases related to Splenic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 422)
# Related Disease Score Top Affiliating Genes
1 hypersplenism 30.2 F2 CD4 ALB
2 miliary tuberculosis 30.1 CRP CD4 ALB ADA
3 portal hypertension 29.8 F2 CD4 ALB
4 pericarditis 29.8 CRP ALB ADA
5 splenic infarction 29.6 PRTN3 F2 CRP ALB
6 splenic abscess 29.6 F2 CRP CD4 ALB
7 pulmonary tuberculosis 29.5 IL2 ALB ADA
8 alcoholic liver cirrhosis 29.4 IL2 F2 ALB
9 crohn's disease 29.3 IL2 CRP CD4 ALB
10 disease by infectious agent 29.1 PRTN3 IL2 CRP CD4 ALB
11 abdominal tuberculosis 28.8 F2 CRP CEACAM5 CD4 ALB ADA
12 pancreatic cancer 28.6 SLC29A1 MSLN KRT19 GRP CEACAM5 CD4
13 liver cirrhosis 28.6 IL2 F2 CRP ALB ADA
14 mycobacterium tuberculosis 1 10.5
15 splenomegaly 10.4
16 intrahepatic gall duct cancer 10.4 KRT19 ALB
17 pulmonary artery leiomyosarcoma 10.4 KRT19 GRP
18 cork-handlers' disease 10.4 CD4 ALB
19 riedel's fibrosing thyroiditis 10.4 CD4 ALB
20 purulent acute otitis media 10.4 PRTN3 CRP
21 wissler-fanconi syndrome 10.4 PRTN3 CD4
22 chronic duodenal ileus 10.4 CRP ALB
23 anterior scleritis 10.4 PRTN3 CRP
24 frontal sinusitis 10.4 PRTN3 CRP
25 orbital plasma cell granuloma 10.4 PRTN3 CRP
26 bicipital tenosynovitis 10.4 PRTN3 CRP
27 multiple cranial nerve palsy 10.4 PRTN3 CRP
28 posterior scleritis 10.4 PRTN3 CRP
29 tolosa-hunt syndrome 10.4 PRTN3 CRP
30 ethmoid sinusitis 10.3 PRTN3 CRP
31 chronic orbital inflammation 10.3 PRTN3 CRP
32 peptic ulcer perforation 10.3 CRP ALB
33 ankylosing spondylitis 3 10.3 CRP ALB
34 chest wall lipoma 10.3 PRTN3 CEACAM5
35 squamous cell bile duct carcinoma 10.3 KRT19 CRP
36 glossopharyngeal nerve disease 10.3 PRTN3 CRP
37 granulomatous angiitis 10.3 PRTN3 CRP
38 chronic intestinal vascular insufficiency 10.3 CRP ALB
39 renal pelvis adenocarcinoma 10.3 KRT19 CEACAM5
40 panophthalmitis 10.3 CRP CD4
41 rheumatoid arthritis interstitial lung disease 10.3 CRP CD4
42 vulvar apocrine adenocarcinoma 10.3 KRT19 CEACAM5
43 hydrops of gallbladder 10.3 CRP ALB
44 paratesticular lipoma 10.3 KRT19 CEACAM5
45 lipoma of spermatic cord 10.3 KRT19 CEACAM5
46 critical illness polyneuropathy 10.3 CRP ALB
47 anal canal adenocarcinoma 10.3 KRT19 CEACAM5
48 primary syphilis 10.3 CRP CD4
49 acute gonococcal endometritis 10.3 CEACAM5 CD4
50 urogenital tuberculosis 10.3 CRP CD4

Graphical network of the top 20 diseases related to Splenic Tuberculosis:



Diseases related to Splenic Tuberculosis

Symptoms & Phenotypes for Splenic Tuberculosis

Drugs & Therapeutics for Splenic Tuberculosis

Search Clinical Trials , NIH Clinical Center for Splenic Tuberculosis

Cochrane evidence based reviews: tuberculosis, splenic

Genetic Tests for Splenic Tuberculosis

Anatomical Context for Splenic Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Splenic Tuberculosis:

19
Spleen

MalaCards organs/tissues related to Splenic Tuberculosis:

40
Spleen, Bone Marrow, Colon, Pancreas, Myeloid

Publications for Splenic Tuberculosis

Articles related to Splenic Tuberculosis:

(show top 50) (show all 143)
# Title Authors PMID Year
1
Isolated Splenic Tuberculosis in an Immunocompetent Patient: A Rare Case. 61
33777552 2021
2
Isolated Splenic Tuberculosis: A Diagnostic Conundrum. 61
33659113 2021
3
Obstructed ileocaecal tuberculosis with splenic tuberculosis and solid pseudopapillary tumour of tail of pancreas in an immunocompetent woman. 61
32878854 2020
4
Spleenic Abscess As A Complication Of Extrapulmonay Tuberculosis. 61
31535530 2019
5
Solitary Splenic Tuberculosis in an Immunocompetent Child: A Case Report. 61
31565614 2019
6
Isolated splenic tuberculosis presenting as an unusual splenic mass. 61
30531044 2018
7
Splenic tuberculosis and multifocal serpiginoid choroiditis. 61
28798995 2018
8
Splenic tuberculosis: a comprehensive review of literature. 61
30426945 2018
9
Isolated Splenic Cold Abscesses in an Immunocompetent Individual. 61
30038737 2018
10
Isolated cystic lymphangiomatosis of spleen in an adult: a diagnostic conundrum. 61
29622712 2018
11
Splenic tuberculosis. 61
29253708 2018
12
Splenic tuberculosis in an immunocompetent patient can be managed conservatively: a case report. 61
26567167 2018
13
Challenges and Results of Laparoscopic Splenectomy for Hematological Diseases in a Developing Country. 61
30155296 2018
14
Portal Venous Thrombosis-Disseminated Tuberculosis in Rheumatoid Arthritis. 61
28764227 2017
15
Isolated splenic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration. 61
28410696 2017
16
Isolated splenic tuberculosis with subsequent paradoxical deterioration: a case report. 61
28438221 2017
17
Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report. 61
28357096 2017
18
Isolated splenic tuberculosis detected only on FDG-PET. 61
30363184 2017
19
Isolated Splenic Cold Abscesses with Perisplenic Extension: Treated Successfully without Splenectomy. 61
28912985 2017
20
Solitary splenic tuberculosis: a case report and review of the literature. 61
27250119 2016
21
Hepatosplenic tuberculosis simulating secondary malignant lesions with cholangitis. 61
27324380 2016
22
Splenic Tuberculosis--Case Report. 61
27172532 2016
23
Splenic tuberculosis in a patient with newly diagnosed advanced HIV infection. 61
27635384 2016
24
A Case of Splenic Tuberculosis Forming a Gastro-splenic Fistula. 61
26387701 2015
25
[Hepato-splenic tuberculosis]. 61
25224582 2015
26
Isolated Splenic Tuberculosis without Any Radiological Focal Lesion. 61
25628658 2015
27
Systemic spread of tuberculosis after surgery for a splenic tuberculous abscess without postoperational antituberculosis treatment: a case report. 61
26635478 2015
28
Bilateral choroidal tuberculoma in miliary tuberculosis - report of a case. 61
25861395 2015
29
A case of isolated splenic tuberculosis. 61
25667987 2015
30
Inflammatory pseudotumour of the spleen associated with splenic tuberculosis. 61
25548610 2014
31
Disseminated tuberculosis with splenic tuberculosis abscess rupture. A rare presentation. 61
25271747 2014
32
PUO--a rare (and forgotten) cause! 61
25906529 2014
33
A rare presentation of splenic tuberculosis with a pseudocyst. 61
24825554 2014
34
Deep vein thrombosis and tuberculosis: a causative link? 61
24859543 2014
35
Isolated splenic tuberculosis in an immunocompetent patient. 61
24599429 2014
36
Splenic tuberculosis: a rare entity. 61
24414191 2014
37
Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis. 61
24348671 2013
38
Primary splenic tubercular abscess in an immunocompromised patient-rapid diagnosis by line probe assay. 61
24179920 2013
39
Splenic tuberculosis presenting as fever of unknown origin with severe neutropenia. 61
23777575 2013
40
Isolated tuberculosis of the spleen: A case report and review of literature. 61
24426436 2013
41
Idiopathic thrombocytopenic purpura associated with splenic tuberculosis: case report. 61
23524902 2013
42
Splenic tuberculosis presenting as ascites in immunocompetant patient. 61
23634345 2013
43
Splenic tuberculosis. 61
23268618 2012
44
Splenic tuberculosis diagnosed by endoscopic ultrasound-guided fine needle aspiration. 61
24949357 2012
45
[Symptomatic hypercalcemia presenting as a case of isolated splenic tuberculosis]. 61
22809966 2012
46
[Splenic tuberculosis in HIV patient]. 61
21377234 2012
47
Isolated tubercular splenic abscess: can we defer splenectomy? Our single experience with anti-tuberculous therapy alone. 61
22361772 2012
48
Splenic tuberculosis in a patient with ankylosing spondylitis treated with adalimumab. 61
22257918 2011
49
A case of mass-forming splenic tuberculosis: MRI findings with emphasis of diffusion-weighted imaging characteristics. 61
21394320 2011
50
A 52-year-old Cuban immigrant with weight loss, dyspnea, and fever. Splenic tuberculosis. 61
21217183 2011

Variations for Splenic Tuberculosis

Expression for Splenic Tuberculosis

Search GEO for disease gene expression data for Splenic Tuberculosis.

Pathways for Splenic Tuberculosis

Pathways related to Splenic Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.4 IL2 CEACAM5 CD4
2
Show member pathways
11.26 IL2 F2 CRP ALB
3 11.02 PRTN3 CD4 ADA

GO Terms for Splenic Tuberculosis

Cellular components related to Splenic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 PRTN3 MSLN IL2 GRP F2 CRP
2 endoplasmic reticulum lumen GO:0005788 9.26 MSLN F2 CD4 ALB
3 extracellular space GO:0005615 9.23 PRTN3 MSLN IL2 GRP F2 CRP

Biological processes related to Splenic Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.35 ADA CD4 CEACAM5 IL2 MSLN
2 positive regulation of calcium-mediated signaling GO:0050850 9.16 ADA CD4
3 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway GO:1900738 8.62 F2 GRP

Sources for Splenic Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....