Aliases & Classifications for Spondylolisthesis

MalaCards integrated aliases for Spondylolisthesis:

Name: Spondylolisthesis 58 39 12 30 56 45 15 17 74

Characteristics:

OMIM:

58
Inheritance:
autosomal dominant


HPO:

33
spondylolisthesis:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:6682
OMIM 58 184200
MeSH 45 D013168
NCIt 51 C35033
ICD10 34 M43.1 M43.10
MedGen 43 C0038016
SNOMED-CT via HPO 70 240221008 263681008
UMLS 74 C0038016

Summaries for Spondylolisthesis

OMIM : 58 Spondylolisthesis is defined as forward slipping of a vertebral body on the one below it. Spondylolysis is defined as a defect in the pars interarticularis without vertebral slipping (summary by Wiltse et al., 1975). (184200)

MalaCards based summary : Spondylolisthesis is related to spondylolysis and spinal stenosis, and has symptoms including back pain An important gene associated with Spondylolisthesis is BMP7 (Bone Morphogenetic Protein 7), and among its related pathways/superpathways are GPCR Pathway and p70S6K Signaling. The drugs Ketamine and Parathyroid hormone have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and testes, and related phenotypes are spondylolysis and spondylolisthesis at l5-s1

Disease Ontology : 12 A bone structure disease that has material basis in displacement located in set of vertebrae.

Wikipedia : 77 Spondylolisthesis is the displacement of one vertebra compared to another. Medical dictionaries define... more...

Related Diseases for Spondylolisthesis

Diseases related to Spondylolisthesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 spondylolysis 31.4 BMP7 FTH1 GDF5
2 spinal stenosis 31.4 BMP7 MMP3
3 degenerative disc disease 30.5 BMP2 GDF5
4 osteoarthritis 30.3 GDF5 MMP3 PTGS2
5 pseudoarthrosis 30.3 BMP2 BMP7
6 jaffer beighton syndrome 11.5
7 scoliosis 10.6
8 frozen shoulder 10.3 GDF5 MMP3
9 radiculopathy 10.3
10 endometrial disease 10.2 ESR1 PTGS2
11 cardiomyopathy, familial hypertrophic, 9 10.2 ESR1 FTH1
12 idiopathic scoliosis 10.2
13 proximal symphalangism 10.2 BMP7 GDF5
14 neural tube defects 10.2
15 spondylosis 10.2
16 osteochondritis dissecans 10.2 BMP7 MMP3
17 brittle bone disorder 10.2
18 spina bifida occulta 10.2
19 oral submucous fibrosis 10.1 MMP3 PTGS2
20 osseous heteroplasia, progressive 10.1 BMP2 BMP7
21 rheumatoid arthritis 10.1
22 arthritis 10.1
23 discitis 10.1
24 coronary artery aneurysm 10.1 MMP3 PRRC2A
25 adenomyosis 10.1 ESR1 PTGS2
26 juvenile polyposis syndrome 10.1 BMP2 PTGS2
27 bone resorption disease 10.1 BMP2 ESR1
28 polykaryocytosis inducer 10.0
29 scoliosis, isolated 1 10.0
30 cerebral palsy 10.0
31 cauda equina syndrome 10.0
32 col1a1/2-related osteogenesis imperfecta 10.0
33 brachydactyly, type a2 10.0 BMP2 GDF5 MMP3
34 bone remodeling disease 10.0 BMP2 ESR1
35 osteoporosis 10.0
36 opiate dependence 10.0
37 spondylitis 10.0
38 depression 10.0
39 cervical adenocarcinoma 9.9 ESR1 PTGS2
40 polyradiculopathy 9.9 BMP2 IVD
41 legg-calve-perthes disease 9.8
42 lipomatosis, multiple 9.8
43 torticollis 9.8
44 down syndrome 9.8
45 disorganization, mouse, homolog of 9.8
46 pycnodysostosis 9.8
47 mucopolysaccharidosis, type ii 9.8
48 intervertebral disc disease 9.8
49 salla disease 9.8
50 basal cell carcinoma 1 9.8

Graphical network of the top 20 diseases related to Spondylolisthesis:



Diseases related to Spondylolisthesis

Symptoms & Phenotypes for Spondylolisthesis

Human phenotypes related to Spondylolisthesis:

33
# Description HPO Frequency HPO Source Accession
1 spondylolysis 33 HP:0003304
2 spondylolisthesis at l5-s1 33 HP:0008489

Symptoms via clinical synopsis from OMIM:

58
Spine:
spondylolysis
spondylolisthesis of l5 on s1
defects in posterior spinous processes of l5 and sacrum

Clinical features from OMIM:

184200

UMLS symptoms related to Spondylolisthesis:


back pain

MGI Mouse Phenotypes related to Spondylolisthesis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.81 BMP2 BMP7 ESR1 FTH1 GDF5 IVD
2 hematopoietic system MP:0005397 9.8 BMP2 BMP7 ESR1 FTH1 MMP3 PROS1
3 nervous system MP:0003631 9.5 BMP2 BMP7 ESR1 FTH1 MMP3 PROS1
4 skeleton MP:0005390 9.1 BMP2 BMP7 ESR1 GDF5 MMP3 PTGS2

Drugs & Therapeutics for Spondylolisthesis

Drugs for Spondylolisthesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 89)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
2
Parathyroid hormone Approved, Investigational Phase 4 9002-64-6
3
Teriparatide Approved, Investigational Phase 4 52232-67-4 16133850
4
Bupivacaine Approved, Investigational Phase 4,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
5
Pregabalin Approved, Illicit, Investigational Phase 4,Not Applicable 148553-50-8 5486971
6
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
7
Calcium Approved, Nutraceutical Phase 4,Phase 2,Not Applicable 7440-70-2 271
8 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
9 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
10 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Early Phase 1
11 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
12 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
13 Calcium, Dietary Phase 4,Phase 2,Not Applicable
14
s 1 (combination) Phase 4,Phase 1,Phase 2,Not Applicable,Early Phase 1
15 Analgesics, Opioid Phase 4,Phase 3,Not Applicable
16 Excitatory Amino Acid Antagonists Phase 4
17 Anesthetics, Dissociative Phase 4
18 Anesthetics, Intravenous Phase 4
19 Narcotics Phase 4,Phase 3,Not Applicable
20 Anesthetics, General Phase 4,Not Applicable
21 Excitatory Amino Acids Phase 4
22 Hormones Phase 4
23 Bone Density Conservation Agents Phase 4
24 Tranquilizing Agents Phase 4
25 Anticonvulsants Phase 4
26 Anti-Anxiety Agents Phase 4
27 Psychotropic Drugs Phase 4
28 calcium channel blockers Phase 4
29 Anesthetics, Local Phase 4,Phase 3,Phase 2
30 Pharmaceutical Solutions Phase 4
31
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3,Early Phase 1 113775-47-6 68602 5311068
32
Racepinephrine Approved Phase 3,Not Applicable 329-65-7 838
33
Epinephrine Approved, Vet_approved Phase 3,Not Applicable 51-43-4 5816
34
Morphine Approved, Investigational Phase 3,Not Applicable 57-27-2 5288826
35
Ropivacaine Approved Phase 3,Phase 2 84057-95-4 71273 175805
36 Analgesics, Non-Narcotic Phase 2, Phase 3,Early Phase 1
37 Hypnotics and Sedatives Phase 2, Phase 3,Early Phase 1
38 Adrenergic alpha-Agonists Phase 2, Phase 3,Phase 3,Early Phase 1
39 Adrenergic Agents Phase 2, Phase 3,Phase 3,Early Phase 1
40 Adrenergic alpha-2 Receptor Agonists Phase 2, Phase 3,Early Phase 1
41 Adrenergic Agonists Phase 2, Phase 3,Phase 3,Early Phase 1
42 Epinephryl borate Phase 3,Not Applicable
43 Mydriatics Phase 3
44 Adrenergic beta-Agonists Phase 3
45 Vasoconstrictor Agents Phase 3
46 Anti-Asthmatic Agents Phase 3
47 Autonomic Agents Phase 3
48 Sympathomimetics Phase 3
49 Respiratory System Agents Phase 3
50 Bronchodilator Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 168)
# Name Status NCT ID Phase Drugs
1 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
2 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
3 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
4 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Completed NCT01292252 Phase 4
5 Post-Market Surveillance Study of the TM Ardis Interbody Fusion System Completed NCT02429908 Phase 4
6 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
7 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation Completed NCT00000410 Phase 4
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
10 Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Recruiting NCT03745040 Phase 4 Liposomal bupivacaine
11 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
12 BIO4 Clinical Case Study: Cervical Spine Active, not recruiting NCT03077204 Phase 4
13 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
14 Efficacy of Using Solum IV and BMC With GFC in TLIF Withdrawn NCT03223701 Phase 4
15 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis Unknown status NCT01618435 Phase 3
16 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Unknown status NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
17 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
18 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
19 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
20 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
21 Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT Enrolling by invitation NCT03884283 Phase 3
22 Peri-Incisional Drug Injection in Lumbar Spine Surgery Not yet recruiting NCT03513445 Phase 3 Morphine;Epinephrine;naropin
23 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
24 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
25 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
26 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
27 Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow Unknown status NCT01335243 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
29 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
30 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
31 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
32 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
33 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Active, not recruiting NCT03100032 Phase 1, Phase 2
34 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
35 Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion Active, not recruiting NCT02205138 Phase 2 ALLOB® cells with ceramic scaffold
36 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
37 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
38 Supine vs. Upright Weight Bearing MRI in the Evaluation of Patients With Lumbar Spondylolisthesis Unknown status NCT02958241 Not Applicable
39 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766 Not Applicable
40 InterFuse® S and T for the Treatment of Scoliosis, Spondylolisthesis and Degenerative Disc Disease (DDD) Unknown status NCT02659722
41 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
42 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379 Not Applicable
43 Post-market Study of the TOPS™ System Unknown status NCT02234154 Not Applicable
44 Post-market Study of the TOPS™ System Unknown status NCT01933607 Not Applicable
45 Post-market Surveillance Study of FLXfit™ TLIF Interbody Fusion Device Unknown status NCT02805985 Not Applicable
46 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
47 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
48 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284 Not Applicable
49 Pre-surgery Physiotherapy for Patients With Specific Low Back Pain Unknown status NCT02454400 Not Applicable
50 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403

Search NIH Clinical Center for Spondylolisthesis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spondylolisthesis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spondylolisthesis:
MPCs, mesenchymal precursor cells for bone fusion
Embryonic/Adult Cultured Cells Related to Spondylolisthesis:
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 24438940 20528753

Cochrane evidence based reviews: spondylolisthesis

Genetic Tests for Spondylolisthesis

Genetic tests related to Spondylolisthesis:

# Genetic test Affiliating Genes
1 Spondylolisthesis 30

Anatomical Context for Spondylolisthesis

MalaCards organs/tissues related to Spondylolisthesis:

42
Bone, Bone Marrow, Testes, Spinal Cord, Colon

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylolisthesis:

20
Set Of Vertebrae

Publications for Spondylolisthesis

Articles related to Spondylolisthesis:

(show top 50) (show all 1951)
# Title Authors Year
1
Anatomic Trajectory for Iliac Screw Placement in Pediatric Scoliosis and Spondylolisthesis: An Alternative to S2-Alar Iliac Portal. ( 30660223 )
2019
2
Selective versus multi-segmental decompression and fusion for multi-segment lumbar spinal stenosis with single-segment degenerative spondylolisthesis. ( 30755227 )
2019
3
Endoscopic ventral decompression for spinal stenosis with degenerative spondylolisthesis by partially removing posterosuperior margin underneath the slipping vertebral body: technical note and outcome evaluation. ( 30825627 )
2019
4
Non-instrumented Lumbar Fusion with BMP for Spinal Stenosis with Spondylolisthesis in the Elderly. ( 30904805 )
2019
5
The Effects of Microdecompression on Patients with Lumbar Degenerative Spinal Stenosis with or without Degenerative Spondylolisthesis. ( 30649783 )
2019
6
Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis. ( 30658613 )
2019
7
Short Lumbosacral Decompression Plus Fixation Does Not Change the Spinopelvic Balance on Patients With Moderate Degenerative Spondylolisthesis and Associated Spinal Stenosis. ( 30660232 )
2019
8
Decompression alone versus decompression with instrumental fusion the NORDSTEN degenerative spondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial. ( 30611229 )
2019
9
Corrigendum to "Stand-alone anterior lumbar interbody fusion for treatment of degenerative spondylolisthesis" [J Clin Neurosci 22(10) (2015) 1619-1624]. ( 30621905 )
2019
10
A Radiological Study of the Association of Facet Joint Tropism and Facet Angulation With Degenerative Spondylolisthesis. ( 30653904 )
2019
11
Surgical Treatment of Developmental Spondylolisthesis: Contemporary Series With a Two-Surgeon Team. ( 30660222 )
2019
12
Self-Image and Health-Related Quality of Life Three Decades After Fusion In Situ for High-Grade Isthmic Spondylolisthesis. ( 30660224 )
2019
13
Radiographic analysis of minimally invasive transforaminal lumbar interbody fusion versus conventional open surgery on sagittal lumbar-pelvic alignment for degenerative spondylolisthesis. ( 30660874 )
2019
14
Comprehensive non-surgical treatment decreased the need for spine surgery in patients with spondylolisthesis: Three-year results. ( 30664502 )
2019
15
Failure to maintain segmental lordosis during TLIF for one-level degenerative spondylolisthesis negatively affects clinical outcome 5 years postoperatively: a prospective cohort of 57 patients. ( 30680634 )
2019
16
Sacro-iliac joint fusion system for high-grade Spondylolisthesis using "Reverse Bohlman technique": a technical report and overview of the literature. ( 30684713 )
2019
17
Transpedicular lag screw placement in traumatic cervical spondylolisthesis: Case report and systematic review of the literature. ( 30737091 )
2019
18
rhBMP in lumber fusion for lumbar spondylolisthesis: A systematic review and meta-analysis. ( 30745112 )
2019
19
Lumbar Interbody Fusions for Degenerative Spondylolisthesis: Review of Techniques, Indications, and Outcomes. ( 30775212 )
2019
20
Comparative analysis of decompression versus decompression and fusion for surgical management of lumbar spondylolisthesis. ( 30794979 )
2019
21
Stable Spondylolisthesis: Should Management Change Based on Presence of Facet Cysts? ( 30807364 )
2019
22
Erratum. Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database. ( 30835714 )
2019
23
Corrigendum to: Obese Patients Benefit, but do not Fare as Well as Nonobese Patients, Following Lumbar Spondylolisthesis Surgery: An Analysis of the Quality Outcomes Database. ( 30860265 )
2019
24
Interbody bone graft via transdiscal screw holes as a treatment for high-grade spondylolisthesis. ( 30876991 )
2019
25
Spinal sagittal alignment and trapezoidal deformity in patients with degenerative cervical spondylolisthesis. ( 30899028 )
2019
26
Direction-changeable cage reduces X-ray exposure in treating isthmic lumbar spondylolisthesis: a retrospective study. ( 30899406 )
2019
27
Ultrasound-guided bilateral lumbar erector spinae plane block for postoperative analgesia after spondylolisthesis correction surgery. ( 30903940 )
2019
28
Criteria for surgical reduction in high-grade lumbosacral spondylolisthesis based on quality of life measures. ( 30915579 )
2019
29
Natural History of Cervical Degenerative Spondylolisthesis. ( 29952882 )
2018
30
The Challenge of Creating Lordosis in High-Grade Dysplastic Spondylolisthesis. ( 29933805 )
2018
31
Motion Analysis in Lumbar Spinal Stenosis With Degenerative Spondylolisthesis: A Feasibility Study of the 3DCT Technique Comparing Laminectomy Versus Bilateral Laminotomy. ( 29939843 )
2018
32
Posterolateral fusion (PLF) vs. transforaminal lumbar interbody fusion (TLIF) for spondylolisthesis: a systematic review and meta-analysis. ( 29452283 )
2018
33
Decompression with or without concomitant fusion in lumbar stenosis due to degenerative spondylolisthesis: a systematic review. ( 29404693 )
2018
34
A novel noninstrumented surgical approach for foramen reconstruction for isthmic spondylolisthesis in patients with radiculopathy: preliminary clinical and radiographic outcomes. ( 29290136 )
2018
35
Spondylolysis and spondylolisthesis: A review of the literature. ( 29881164 )
2018
36
Reliability and Clinical Utility of the CARDS Classification for Degenerative Spondylolisthesis. ( 28719453 )
2018
37
Spondylolisthesis is Common, Early, and Severe in Loeys-Dietz Syndrome. ( 29889773 )
2018
38
Radiological and functional outcomes of high-grade spondylolisthesis treated by intrasacral fixation, dome resection and circumferential fusion: a retrospective series of 20 consecutive cases with a minimum of 2A years follow-up. ( 29353326 )
2018
39
Direction-changeable lumbar cage versus traditional lumbar cage for treating lumbar spondylolisthesis: A retrospective study. ( 29443791 )
2018
40
Mild (not severe) disc degeneration is implicated in the progression of bilateral L5 spondylolysis to spondylolisthesis. ( 29609581 )
2018
41
Evaluation of the facet joints with magnetic resonance images in the patients with disc degeneration and spondylolisthesis. ( 29909481 )
2018
42
Long-term Minimum Clinically Important Difference(MCID) in Health Related Quality of Life Scores After Instrumented Lumbar Interbody Fusion for Low-Grade Isthmic Spondylolisthesis. ( 29920389 )
2018
43
Does Surgically Managed Grade I Degenerative Lumbar Spondylolisthesis Require Fusion? ( 29975202 )
2018
44
Minimally invasive anterior and lateral transpsoas approaches for closed reduction of grade II spondylolisthesis: initial clinical and radiographic experience. ( 29290134 )
2018
45
Increased rate of lumbar spondylolisthesis in rheumatoid arthritis: a case-control study. ( 29956820 )
2018
46
Comparative Utility of Dynamic and Static Imaging in the Management of Lumbar Spondylolisthesis. ( 29929030 )
2018
47
Assessment of radiographic and clinical outcomes of an articulating expandable interbody cage in minimally invasive transforaminal lumbar interbody fusion for spondylolisthesis. ( 29290133 )
2018
48
Increased PT/SS may play an important role in the pathogenesis of lumbar spondylolisthesis with degenerative lumbar scoliosis. ( 29358108 )
2018
49
Radiographic Classification for Degenerative Spondylolisthesis of the Lumbar Spine Based on Sagittal Balance: A Reliability Study. ( 29886905 )
2018
50
Posterior reversible encephalopathy syndrome with status epilepticus following surgery for lumbar stenosis and spondylolisthesis: case report. ( 29864559 )
2018

Variations for Spondylolisthesis

Expression for Spondylolisthesis

Search GEO for disease gene expression data for Spondylolisthesis.

Pathways for Spondylolisthesis

GO Terms for Spondylolisthesis

Cellular components related to Spondylolisthesis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 BMP2 BMP7 FTH1 GDF5 MMP3 PROS1

Biological processes related to Spondylolisthesis according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.91 BMP2 FTH1 IVD PTGS2
2 negative regulation of cell proliferation GO:0008285 9.84 BMP2 BMP7 FTH1 PTGS2
3 regulation of apoptotic process GO:0042981 9.71 BMP2 BMP7 ESR1 GDF5
4 response to estradiol GO:0032355 9.7 BMP7 ESR1 PTGS2
5 positive regulation of neuron differentiation GO:0045666 9.67 BMP2 BMP7 GDF5
6 BMP signaling pathway GO:0030509 9.65 BMP2 BMP7 GDF5
7 cartilage development GO:0051216 9.63 BMP2 BMP7 GDF5
8 steroid hormone mediated signaling pathway GO:0043401 9.62 BMP7 ESR1
9 positive regulation of cell death GO:0010942 9.62 BMP7 PTGS2
10 positive regulation of cell differentiation GO:0045597 9.61 BMP2 BMP7
11 positive regulation of epithelial to mesenchymal transition GO:0010718 9.6 BMP2 BMP7
12 bone mineralization GO:0030282 9.59 BMP2 PTGS2
13 chondrocyte differentiation GO:0002062 9.58 BMP2 GDF5
14 epithelial to mesenchymal transition GO:0001837 9.58 BMP2 BMP7
15 cellular response to BMP stimulus GO:0071773 9.57 BMP2 BMP7
16 positive regulation of bone mineralization GO:0030501 9.56 BMP2 BMP7
17 response to vitamin D GO:0033280 9.55 BMP7 PTGS2
18 mesenchymal cell differentiation GO:0048762 9.51 BMP2 BMP7
19 cell development GO:0048468 9.5 BMP2 BMP7 GDF5
20 regulation of branching involved in prostate gland morphogenesis GO:0060687 9.43 BMP7 ESR1
21 regulation of MAPK cascade GO:0043408 9.43 BMP2 BMP7 GDF5
22 mesenchyme development GO:0060485 9.37 BMP2 BMP7
23 SMAD protein signal transduction GO:0060395 9.33 BMP2 BMP7 GDF5
24 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.13 BMP2 BMP7 GDF5
25 negative regulation of cell cycle GO:0045786 8.8 BMP2 BMP7 PTGS2

Molecular functions related to Spondylolisthesis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 BMP2 BMP7 GDF5
2 growth factor activity GO:0008083 9.33 BMP2 BMP7 GDF5
3 BMP receptor binding GO:0070700 8.96 BMP2 BMP7
4 transforming growth factor beta receptor binding GO:0005160 8.8 BMP2 BMP7 GDF5

Sources for Spondylolisthesis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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