Aliases & Classifications for Spondylolisthesis

MalaCards integrated aliases for Spondylolisthesis:

Name: Spondylolisthesis 58 39 12 56 45 15 17 74

Characteristics:

OMIM:

58
Inheritance:
autosomal dominant


HPO:

33
spondylolisthesis:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:6682
OMIM 58 184200
MeSH 45 D013168
NCIt 51 C35033
ICD10 34 M43.1 M43.10
MedGen 43 C0038016
SNOMED-CT via HPO 70 240221008 263681008
UMLS 74 C0038016

Summaries for Spondylolisthesis

OMIM : 58 Spondylolisthesis is defined as forward slipping of a vertebral body on the one below it. Spondylolysis is defined as a defect in the pars interarticularis without vertebral slipping (summary by Wiltse et al., 1975). (184200)

MalaCards based summary : Spondylolisthesis is related to spinal stenosis and spondylolysis, and has symptoms including back pain An important gene associated with Spondylolisthesis is BMP7 (Bone Morphogenetic Protein 7), and among its related pathways/superpathways are GPCR Pathway and p70S6K Signaling. The drugs Ketamine and Parathyroid hormone have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and testes, and related phenotypes are spondylolysis and spondylolisthesis at l5-s1

Disease Ontology : 12 A bone structure disease that has material basis in displacement located in set of vertebrae.

Wikipedia : 77 Spondylolisthesis is the displacement of one vertebra compared to another. While some medical... more...

Related Diseases for Spondylolisthesis

Diseases related to Spondylolisthesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 spinal stenosis 31.4 BMP7 MMP3
2 spondylolysis 31.4 BMP7 FTH1 GDF5
3 osteoarthritis 30.4 GDF5 MMP3 PTGS2
4 degenerative disc disease 30.4 BMP2 GDF5
5 pseudoarthrosis 30.3 BMP2 BMP7
6 jaffer beighton syndrome 11.5
7 scoliosis 10.6
8 radiculopathy 10.3
9 frozen shoulder 10.3 GDF5 MMP3
10 endometrial disease 10.2 ESR1 PTGS2
11 idiopathic scoliosis 10.2
12 cardiomyopathy, familial hypertrophic, 9 10.2 ESR1 FTH1
13 proximal symphalangism 10.2 BMP7 GDF5
14 neural tube defects 10.2
15 spondylosis 10.2
16 osteochondritis dissecans 10.2 BMP7 MMP3
17 brittle bone disorder 10.2
18 spina bifida occulta 10.2
19 col1a1/2-related osteogenesis imperfecta 10.2
20 oral submucous fibrosis 10.1 MMP3 PTGS2
21 polykaryocytosis inducer 10.1
22 rheumatoid arthritis 10.1
23 arthritis 10.1
24 discitis 10.1
25 adenomyosis 10.1 ESR1 PTGS2
26 osseous heteroplasia, progressive 10.1 BMP2 BMP7
27 scoliosis, isolated 1 10.1
28 bone mineral density quantitative trait locus 15 10.1
29 cerebral palsy 10.1
30 cauda equina syndrome 10.1
31 juvenile polyposis syndrome 10.0 BMP2 PTGS2
32 bone resorption disease 10.0 BMP2 ESR1
33 polyradiculopathy 10.0 BMP2 IVD
34 brachydactyly, type a2 10.0 BMP2 GDF5 MMP3
35 neurofibromatosis, type iv, of riccardi 10.0
36 osteoporosis 10.0
37 salla disease 10.0
38 bone mineral density quantitative trait locus 8 10.0
39 myelomeningocele 10.0
40 opiate dependence 10.0
41 spondylitis 10.0
42 depression 10.0
43 bone remodeling disease 9.9 BMP2 ESR1
44 cervical adenocarcinoma 9.9 ESR1 PTGS2
45 basal cell nevus syndrome 9.8
46 legg-calve-perthes disease 9.8
47 lipomatosis, multiple 9.8
48 torticollis 9.8
49 down syndrome 9.8
50 disorganization, mouse, homolog of 9.8

Graphical network of the top 20 diseases related to Spondylolisthesis:



Diseases related to Spondylolisthesis

Symptoms & Phenotypes for Spondylolisthesis

Human phenotypes related to Spondylolisthesis:

33
# Description HPO Frequency HPO Source Accession
1 spondylolysis 33 HP:0003304
2 spondylolisthesis at l5-s1 33 HP:0008489

Symptoms via clinical synopsis from OMIM:

58
Spine:
spondylolysis
spondylolisthesis of l5 on s1
defects in posterior spinous processes of l5 and sacrum

Clinical features from OMIM:

184200

UMLS symptoms related to Spondylolisthesis:


back pain

GenomeRNAi Phenotypes related to Spondylolisthesis according to GeneCards Suite gene sharing:

27 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.58 PTGS2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.58 PTGS2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.58 PTGS2
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.58 IVD
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.58 IDS
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 9.58 IDS
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 9.58 IDS
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.58 IDS
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.58 IDS IVD PTGS2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.58 IDS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.58 IDS PTGS2
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-48 9.58 IDS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.58 PTGS2
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.58 IDS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-98 9.58 PTGS2

MGI Mouse Phenotypes related to Spondylolisthesis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.06 BMP2 BMP7 ESR1 FTH1 IDS MMP3
2 homeostasis/metabolism MP:0005376 10.03 BMP2 ESR1 FTH1 IDS IVD MMP3
3 mortality/aging MP:0010768 9.96 BMP2 BMP7 ESR1 FTH1 GDF5 IDS
4 immune system MP:0005387 9.95 BMP2 BMP7 ESR1 FTH1 IDS MMP3
5 limbs/digits/tail MP:0005371 9.77 BMP2 BMP7 ESR1 GDF5 IDS
6 nervous system MP:0003631 9.76 BMP2 BMP7 ESR1 FTH1 IDS MMP3
7 liver/biliary system MP:0005370 9.72 ESR1 FTH1 IDS PROS1 PTGS2
8 reproductive system MP:0005389 9.43 BMP2 BMP7 ESR1 GDF5 IDS PTGS2
9 skeleton MP:0005390 9.17 BMP2 BMP7 ESR1 GDF5 IDS MMP3

Drugs & Therapeutics for Spondylolisthesis

Drugs for Spondylolisthesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 90)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
2
Parathyroid hormone Approved, Investigational Phase 4 9002-64-6
3
Teriparatide Approved, Investigational Phase 4 52232-67-4 16133850
4
Bupivacaine Approved, Investigational Phase 4,Not Applicable,Early Phase 1 38396-39-3, 2180-92-9 2474
5
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
6
Pregabalin Approved, Illicit, Investigational Phase 4,Not Applicable 148553-50-8 5486971
7
Calcium Approved, Nutraceutical Phase 4,Phase 2,Not Applicable 7440-70-2 271
8 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
9 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
10 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Early Phase 1
11 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
12 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1
13 Calcium, Dietary Phase 4,Phase 2,Not Applicable
14
s 1 (combination) Phase 4,Phase 1,Phase 2,Not Applicable,Early Phase 1
15 Narcotics Phase 4,Phase 3,Not Applicable
16 Excitatory Amino Acids Phase 4
17 Excitatory Amino Acid Antagonists Phase 4
18 Analgesics, Opioid Phase 4,Phase 3,Not Applicable
19 Anesthetics, General Phase 4,Not Applicable
20 Anesthetics, Intravenous Phase 4
21 Anesthetics, Dissociative Phase 4
22 Bone Density Conservation Agents Phase 4
23 Hormones Phase 4
24 Anti-Anxiety Agents Phase 4
25 Tranquilizing Agents Phase 4
26 Psychotropic Drugs Phase 4
27 calcium channel blockers Phase 4
28 Anticonvulsants Phase 4
29 Anesthetics, Local Phase 4,Phase 3,Phase 2
30 Pharmaceutical Solutions Phase 4
31
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3,Early Phase 1 113775-47-6 5311068 68602
32
Racepinephrine Approved Phase 3,Not Applicable 329-65-7 838
33
Epinephrine Approved, Vet_approved Phase 3,Not Applicable 51-43-4 5816
34
Morphine Approved, Investigational Phase 3,Not Applicable 57-27-2 5288826
35
Ropivacaine Approved Phase 3,Phase 2 84057-95-4 175805 71273
36 Adrenergic Agonists Phase 2, Phase 3,Phase 3,Early Phase 1
37 Adrenergic alpha-Agonists Phase 2, Phase 3,Phase 3,Early Phase 1
38 Adrenergic Agents Phase 2, Phase 3,Phase 3,Early Phase 1
39 Adrenergic alpha-2 Receptor Agonists Phase 2, Phase 3,Early Phase 1
40 Analgesics, Non-Narcotic Phase 2, Phase 3,Early Phase 1
41 Hypnotics and Sedatives Phase 2, Phase 3,Early Phase 1
42 Epinephryl borate Phase 3,Not Applicable
43 Sympathomimetics Phase 3
44 Bronchodilator Agents Phase 3
45 Respiratory System Agents Phase 3
46 Anti-Asthmatic Agents Phase 3
47 Mydriatics Phase 3
48 Vasoconstrictor Agents Phase 3
49 Autonomic Agents Phase 3
50 Adrenergic beta-Agonists Phase 3

Interventional clinical trials:

(show top 50) (show all 174)
# Name Status NCT ID Phase Drugs
1 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
2 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
3 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
4 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Completed NCT01292252 Phase 4
5 Post-Market Surveillance Study of the TM Ardis Interbody Fusion System Completed NCT02429908 Phase 4
6 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
7 Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation Completed NCT00000410 Phase 4
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
10 Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Recruiting NCT03745040 Phase 4 Liposomal bupivacaine
11 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
12 BIO4 Clinical Case Study: Cervical Spine Active, not recruiting NCT03077204 Phase 4
13 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
14 Efficacy of Using Solum IV and BMC With GFC in TLIF Withdrawn NCT03223701 Phase 4
15 The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis Unknown status NCT01618435 Phase 3
16 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Unknown status NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
17 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
18 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
19 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
20 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
21 Peri-Incisional Drug Injection in Lumbar Spine Surgery Recruiting NCT03513445 Phase 3 Morphine;Epinephrine;naropin
22 Prospective, Multi-center Study to Assess Posterolateral Fusion Using FIBERGRAFT Enrolling by invitation NCT03884283 Phase 3
23 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
24 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
25 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
26 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
27 Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow Unknown status NCT01335243 Phase 2
28 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
29 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
30 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
31 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
32 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
33 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Active, not recruiting NCT03100032 Phase 1, Phase 2
34 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
35 Phase 2a Study on Allogeneic Osteoblastic Cells Implantation in Lumbar Spinal Fusion Active, not recruiting NCT02205138 Phase 2 ALLOB® cells with ceramic scaffold
36 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
37 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
38 Supine vs. Upright Weight Bearing MRI in the Evaluation of Patients With Lumbar Spondylolisthesis Unknown status NCT02958241 Not Applicable
39 Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression Unknown status NCT01338766 Not Applicable
40 InterFuse® S and T for the Treatment of Scoliosis, Spondylolisthesis and Degenerative Disc Disease (DDD) Unknown status NCT02659722
41 Prospective Study of Minimally Invasive Spine Surgery Unknown status NCT01045473
42 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379 Not Applicable
43 Post-market Study of the TOPS™ System Unknown status NCT02234154 Not Applicable
44 Post-market Study of the TOPS™ System Unknown status NCT01933607 Not Applicable
45 Post-market Surveillance Study of FLXfit™ TLIF Interbody Fusion Device Unknown status NCT02805985 Not Applicable
46 A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP® Unknown status NCT02225444
47 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
48 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
49 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284 Not Applicable
50 Pre-surgery Physiotherapy for Patients With Specific Low Back Pain Unknown status NCT02454400 Not Applicable

Search NIH Clinical Center for Spondylolisthesis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Spondylolisthesis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Spondylolisthesis:
MPCs, mesenchymal precursor cells for bone fusion
Embryonic/Adult Cultured Cells Related to Spondylolisthesis:
Mesenchymal Precursor Cells (STRO-3 selected) PMIDs: 24438940 20528753

Cochrane evidence based reviews: spondylolisthesis

Genetic Tests for Spondylolisthesis

Anatomical Context for Spondylolisthesis

MalaCards organs/tissues related to Spondylolisthesis:

42
Bone, Bone Marrow, Testes, Spinal Cord, Colon

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylolisthesis:

20
Set Of Vertebrae

Publications for Spondylolisthesis

Articles related to Spondylolisthesis:

(show top 50) (show all 1979)
# Title Authors Year
1
Succesful management of a giant anterior sacral meningocele associated with low-dysplastic spondylolisthesis from single posterior approach: case report. ( 31009790 )
2019
2
The progression of osteoarthritis of the hip increases degenerative lumbar spondylolisthesis and causes the change of spinopelvic alignment. ( 30976139 )
2019
3
Isthmic spondylolisthesis and interspinous process device. Hype, hope, or contraindication? ( 30964157 )
2019
4
Spondylolisthesis with an uncommon congenital deformity of L4-L5 vertebral fusion treated by OLIF: a case report. ( 30974268 )
2019
5
Decompression Versus Fusion for Grade I Degenerative Spondylolisthesis: A Meta-Analysis. ( 30984494 )
2019
6
EFFECTS OF SAGITTAL BALANCE DIFFERENCES ON SPONDYLOLISTHESIS. ( 30988660 )
2019
7
Restoration of normal pelvic balance from surgical reduction in high-grade spondylolisthesis. ( 30989359 )
2019
8
Does minimally invasive fusion technique influence surgical outcomes in isthmic spondylolisthesis? ( 30265165 )
2019
9
HISTORY OF DEGENERATIVE SPONDYLOLISTHESIS: FROM ANATOMICAL DESCRIPTION TO SURGICAL MANAGEMENT. ( 30951729 )
2019
10
Accuracy of Robot-Assisted Percutaneous Pedicle Screw Placement for Treatment of Lumbar Spondylolisthesis: A Comparative Cohort Study. ( 30946733 )
2019
11
Clinical, Functional, and Radiologic Outcome of Single- and Double-Level Transforaminal Lumbar Interbody Fusion in Patients with Low-Grade Spondylolisthesis. ( 30937032 )
2019
12
Development of a machine learning algorithm predicting discharge placement after surgery for spondylolisthesis. ( 30919114 )
2019
13
Criteria for surgical reduction in high-grade lumbosacral spondylolisthesis based on quality of life measures. ( 30915579 )
2019
14
Ultrasound-guided bilateral lumbar erector spinae plane block for postoperative analgesia after spondylolisthesis correction surgery. ( 30903940 )
2019
15
Direction-changeable cage reduces X-ray exposure in treating isthmic lumbar spondylolisthesis: a retrospective study. ( 30899406 )
2019
16
Spinal sagittal alignment and trapezoidal deformity in patients with degenerative cervical spondylolisthesis. ( 30899028 )
2019
17
Interbody bone graft via transdiscal screw holes as a treatment for high-grade spondylolisthesis. ( 30876991 )
2019
18
Corrigendum to: Obese Patients Benefit, but do not Fare as Well as Nonobese Patients, Following Lumbar Spondylolisthesis Surgery: An Analysis of the Quality Outcomes Database. ( 30860265 )
2019
19
Erratum. Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database. ( 30835714 )
2019
20
Stable Spondylolisthesis: Should Management Change Based on Presence of Facet Cysts? ( 30807364 )
2019
21
Comparative analysis of decompression versus decompression and fusion for surgical management of lumbar spondylolisthesis. ( 30794979 )
2019
22
Lumbar Interbody Fusions for Degenerative Spondylolisthesis: Review of Techniques, Indications, and Outcomes. ( 30775212 )
2019
23
rhBMP in lumber fusion for lumbar spondylolisthesis: A systematic review and meta-analysis. ( 30745112 )
2019
24
Transpedicular lag screw placement in traumatic cervical spondylolisthesis: Case report and systematic review of the literature. ( 30737091 )
2019
25
Sacro-iliac joint fusion system for high-grade Spondylolisthesis using "Reverse Bohlman technique": a technical report and overview of the literature. ( 30684713 )
2019
26
Failure to maintain segmental lordosis during TLIF for one-level degenerative spondylolisthesis negatively affects clinical outcome 5 years postoperatively: a prospective cohort of 57 patients. ( 30680634 )
2019
27
Comprehensive non-surgical treatment decreased the need for spine surgery in patients with spondylolisthesis: Three-year results. ( 30664502 )
2019
28
Radiographic analysis of minimally invasive transforaminal lumbar interbody fusion versus conventional open surgery on sagittal lumbar-pelvic alignment for degenerative spondylolisthesis. ( 30660874 )
2019
29
Self-Image and Health-Related Quality of Life Three Decades After Fusion In Situ for High-Grade Isthmic Spondylolisthesis. ( 30660224 )
2019
30
Surgical Treatment of Developmental Spondylolisthesis: Contemporary Series With a Two-Surgeon Team. ( 30660222 )
2019
31
A Radiological Study of the Association of Facet Joint Tropism and Facet Angulation With Degenerative Spondylolisthesis. ( 30653904 )
2019
32
Corrigendum to "Stand-alone anterior lumbar interbody fusion for treatment of degenerative spondylolisthesis" [J Clin Neurosci 22(10) (2015) 1619-1624]. ( 30621905 )
2019
33
Decompression alone versus decompression with instrumental fusion the NORDSTEN degenerative spondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial. ( 30611229 )
2019
34
A novel technique for stabilization of high-grade spondylolisthesis with transvertebral fusion without reduction. ( 30470650 )
2019
35
Minimally Invasive Versus Traditional Open Transforaminal Lumbar Interbody Fusion for the Treatment of Single-Level Spondylolisthesis Grades 1 and 2: A Systematic Review and Meta-Analysis. ( 30414524 )
2019
36
High Sacral Endplate Inclination Vector Forces Are Associated with Pars Fracture-Mediated Lumbosacral Spondylolisthesis. ( 30391597 )
2019
37
Perioperative Effects Associated With the Surgical Treatment of Degenerative Spondylolisthesis: Interbody Versus No Interbody. ( 30334823 )
2019
38
The Relationship of Facet Joint Orientation and Tropism with Lumbar Disc Herniation and Degenerative Spondylolisthesis in the Lower Lumbar Spine. ( 30326694 )
2019
39
Age-related changes in axial and sagittal orientation of the facet joints: Comparison with changes in degenerative spondylolisthesis. ( 30318428 )
2019
40
The impact of surgical reduction of high-grade lumbosacral spondylolisthesis on proximal femoral angle and quality of life. ( 30296577 )
2019
41
Degenerative Lumbar Spondylolisthesis: Biochemical Aspects and Evaluation of Stabilization Surgery Extent in Terms of Adjacent Segment Disease Theory. ( 30278292 )
2019
42
Long-term outcome after spinal fusion for isthmic spondylolisthesis in adults. ( 30142456 )
2019
43
Long-Term Costs of Maximum Nonoperative Treatments in Patients With Symptomatic Lumbar Stenosis or Spondylolisthesis that Ultimately Required Surgery: A 5-Year Cost Analysis. ( 30130337 )
2019
44
Evaluation of foraminal cross-sectional area in lumbar spondylolisthesis using kinematic MRI. ( 30054742 )
2019
45
Increased Proportion of Fusion Surgery for Degenerative Lumbar Spondylolisthesis and Changes in Reoperation Rate: A Nationwide Cohort Study With a Minimum 5-Year Follow-up. ( 30028778 )
2019
46
Does Systemic Administration of Parathyroid Hormone After Noninstrumented Spinal Fusion Surgery Improve Fusion Rates and Fusion Mass in Elderly Patients Compared to Placebo in Patients With Degenerative Lumbar Spondylolisthesis? ( 30005049 )
2019
47
Expectations for Postoperative Improvement in Health-Related Quality of Life in Young Patients With Lumbosacral Spondylolisthesis: A Prospective Cohort Study. ( 30005048 )
2019
48
Does Surgically Managed Grade I Degenerative Lumbar Spondylolisthesis Require Fusion? ( 29975202 )
2019
49
Natural History of Cervical Degenerative Spondylolisthesis. ( 29952882 )
2019
50
Artificial Intelligence for the Treatment of Lumbar Spondylolisthesis. ( 31078239 )
2019

Variations for Spondylolisthesis

Expression for Spondylolisthesis

Search GEO for disease gene expression data for Spondylolisthesis.

Pathways for Spondylolisthesis

GO Terms for Spondylolisthesis

Cellular components related to Spondylolisthesis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 BMP2 BMP7 FTH1 GDF5 MMP3 PROS1

Biological processes related to Spondylolisthesis according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.91 BMP2 FTH1 IVD PTGS2
2 negative regulation of cell proliferation GO:0008285 9.84 BMP2 BMP7 FTH1 PTGS2
3 regulation of apoptotic process GO:0042981 9.71 BMP2 BMP7 ESR1 GDF5
4 response to estradiol GO:0032355 9.7 BMP7 ESR1 PTGS2
5 positive regulation of neuron differentiation GO:0045666 9.67 BMP2 BMP7 GDF5
6 BMP signaling pathway GO:0030509 9.65 BMP2 BMP7 GDF5
7 cartilage development GO:0051216 9.63 BMP2 BMP7 GDF5
8 steroid hormone mediated signaling pathway GO:0043401 9.62 BMP7 ESR1
9 positive regulation of cell death GO:0010942 9.62 BMP7 PTGS2
10 positive regulation of cell differentiation GO:0045597 9.61 BMP2 BMP7
11 positive regulation of epithelial to mesenchymal transition GO:0010718 9.6 BMP2 BMP7
12 bone mineralization GO:0030282 9.59 BMP2 PTGS2
13 epithelial to mesenchymal transition GO:0001837 9.58 BMP2 BMP7
14 cellular response to BMP stimulus GO:0071773 9.57 BMP2 BMP7
15 positive regulation of bone mineralization GO:0030501 9.56 BMP2 BMP7
16 response to vitamin D GO:0033280 9.55 BMP7 PTGS2
17 mesenchymal cell differentiation GO:0048762 9.51 BMP2 BMP7
18 cell development GO:0048468 9.5 BMP2 BMP7 GDF5
19 regulation of branching involved in prostate gland morphogenesis GO:0060687 9.43 BMP7 ESR1
20 regulation of MAPK cascade GO:0043408 9.43 BMP2 BMP7 GDF5
21 mesenchyme development GO:0060485 9.37 BMP2 BMP7
22 SMAD protein signal transduction GO:0060395 9.33 BMP2 BMP7 GDF5
23 chondrocyte differentiation GO:0002062 9.28 BMP2
24 positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 9.13 BMP2 BMP7 GDF5
25 negative regulation of cell cycle GO:0045786 8.8 BMP2 BMP7 PTGS2

Molecular functions related to Spondylolisthesis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 BMP2 BMP7 GDF5
2 growth factor activity GO:0008083 9.33 BMP2 BMP7 GDF5
3 BMP receptor binding GO:0070700 8.96 BMP2 BMP7
4 transforming growth factor beta receptor binding GO:0005160 8.8 BMP2 BMP7 GDF5

Sources for Spondylolisthesis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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