MCID: SPN020
MIFTS: 51

Spondylosis

Categories: Bone diseases, Neuronal diseases

Aliases & Classifications for Spondylosis

MalaCards integrated aliases for Spondylosis:

Name: Spondylosis 12 44 15 73
Spondylogenic Compression of Thoracic Spinal Cord 12
Spondylogenic Compression of Lumbar Spinal Cord 12
Thoracic or Lumbar Spondylosis with Myelopathy 12
Lumbosacral Spondylosis Without Myelopathy 12
Lumbar Spondylosis with Myelopathy 12
Spondylosis with Myelopathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2247
ICD10 33 M47 M47.9
ICD9CM 35 721.9
MeSH 44 D055009
SNOMED-CT 68 8847002
UMLS 73 C0038019

Summaries for Spondylosis

Disease Ontology : 12 An bone structure disease that involves degeneration between vertebra located in vertebral column.

MalaCards based summary : Spondylosis, also known as spondylogenic compression of thoracic spinal cord, is related to head injury and osteoporosis. An important gene associated with Spondylosis is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways/superpathways are Parathyroid hormone synthesis, secretion and action and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. The drugs Dexamethasone and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and brain, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 76 Spondylosis is the degeneration of the spinal column from any cause. In the more narrow sense it refers... more...

Related Diseases for Spondylosis

Diseases related to Spondylosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 head injury 30.0 ENO2 S100B
2 osteoporosis 28.7 ESR1 HMGCR IL1B KL PTH VDR
3 spondylosis, cervical 12.2
4 central cord syndrome 11.4
5 cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 11.3
6 spastic paraplegia 25 11.1
7 osteoarthritis 10.3
8 radiculopathy 10.3
9 syringomyelia 10.3
10 intracranial cysts 10.2 ENO2 S100B
11 bednar tumor 10.2 ENO2 S100B
12 epithelioid malignant peripheral nerve sheath tumor 10.2 ENO2 S100B
13 ossifying fibromyxoid tumor 10.2 ENO2 S100B
14 middle cerebral artery infarction 10.2 ENO2 S100B
15 pineocytoma 10.2 ENO2 S100B
16 papillary ependymoma 10.2 ENO2 S100B
17 clear cell adenoma 10.2 PTH S100B
18 granular cell tumor 10.2 ENO2 S100B
19 subependymal giant cell astrocytoma 10.2 ENO2 S100B
20 meningeal melanocytoma 10.2 ENO2 S100B
21 connective tissue benign neoplasm 10.2 ENO2 PTH
22 cerebral primitive neuroectodermal tumor 10.2 ENO2 S100B
23 hyperostosis 10.2
24 dysphagia 10.2
25 traumatic brain injury 10.2 ENO2 S100B
26 brain injury 10.2 ENO2 S100B
27 cloacogenic carcinoma 10.2 ENO2 PTH
28 olfactory neuroblastoma 10.2 ENO2 S100B
29 acute mountain sickness 10.2 ENO2 S100B
30 spondylolisthesis 10.2
31 spinal cord injury 10.2
32 extraosseous ewing's sarcoma 10.2 ENO2 S100B
33 calciphylaxis 10.2 PTH VDR
34 optic nerve glioma 10.2 ENO2 S100B
35 hypercalcemia, infantile, 1 10.2 PTH VDR
36 campylobacteriosis 10.1 IL1B VDR
37 cervical clear cell adenocarcinoma 10.1 ENO2 ESR1
38 syringoma 10.1 ESR1 S100B
39 pilomatrixoma 10.1 ENO2 S100B
40 vulvar vestibulitis syndrome 10.1 ESR1 IL1B
41 multiple sclerosis 10.1
42 diffuse idiopathic skeletal hyperostosis 10.1
43 secondary hyperparathyroidism of renal origin 10.1 PTH VDR
44 ganglioglioma 10.1 ENO2 S100B
45 parathyroid gland disease 10.1 PTH VDR
46 hidradenocarcinoma 10.1 ESR1 S100B
47 endometrial disease 10.1 ESR1 IL1B
48 vaginitis 10.1 ESR1 IL1B
49 renal osteodystrophy 10.1 PTH VDR
50 extrapulmonary tuberculosis 10.1 IL1B VDR

Comorbidity relations with Spondylosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Spondylosis:



Diseases related to Spondylosis

Symptoms & Phenotypes for Spondylosis

MGI Mouse Phenotypes related to Spondylosis:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.13 ENO2 ESR1 HELLS HMGCR HTRA1 IL1B
2 cardiovascular system MP:0005385 10.04 ESR1 HTRA1 IL1B KL PTH VDR
3 homeostasis/metabolism MP:0005376 10.02 ESR1 HELLS HMGCR IL1B KL PTH
4 craniofacial MP:0005382 9.95 ENO2 IL1B KL PTH VDR WRN
5 hematopoietic system MP:0005397 9.95 ESR1 HELLS IL1B KL PTH VDR
6 endocrine/exocrine gland MP:0005379 9.93 ESR1 HELLS KL PTH VDR WRN
7 immune system MP:0005387 9.87 ESR1 HELLS IL1B KL PTH VDR
8 integument MP:0010771 9.8 ESR1 HELLS IL1B KL S100B VDR
9 limbs/digits/tail MP:0005371 9.63 ESR1 HELLS KL PTH VDR WRN
10 mortality/aging MP:0010768 9.56 ESR1 HELLS HMGCR IL1B KL PTH
11 skeleton MP:0005390 9.23 ESR1 HELLS HTRA1 IL1B KL PTH

Drugs & Therapeutics for Spondylosis

Drugs for Spondylosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 115)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 50-02-2 5743
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 1177-87-3
3
Teriparatide Approved, Investigational Phase 4 52232-67-4 16133850
4
Pregabalin Approved, Illicit, Investigational Phase 4,Not Applicable 148553-50-8 5486971
5
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
6
Triamcinolone Approved, Vet_approved Phase 4,Not Applicable 124-94-7 31307
7
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
8
Bupivacaine Approved, Investigational Phase 4,Not Applicable 2180-92-9, 38396-39-3 2474
9
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
10 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable
11 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
12 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable
13 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
14 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable
15 BB 1101 Phase 4,Phase 2,Not Applicable
16 Hormones Phase 4,Phase 3,Not Applicable
17 Bone Density Conservation Agents Phase 4
18 Calcium, Dietary Phase 4
19 Psychotropic Drugs Phase 4
20 calcium channel blockers Phase 4
21 Anti-Anxiety Agents Phase 4
22 Anticonvulsants Phase 4
23 Tranquilizing Agents Phase 4
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
25 Hormone Antagonists Phase 4,Phase 3,Not Applicable
26 Immunosuppressive Agents Phase 4,Not Applicable
27 Anti-Arrhythmia Agents Phase 4
28 Anesthetics, Local Phase 4,Phase 3,Phase 2
29 glucocorticoids Phase 4,Phase 3,Not Applicable
30 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
31 Diuretics, Potassium Sparing Phase 4
32 Immunologic Factors Phase 4,Not Applicable
33 Sodium Channel Blockers Phase 4
34 triamcinolone acetonide Phase 4,Not Applicable
35 Triamcinolone hexacetonide Phase 4,Not Applicable
36 Triamcinolone diacetate Phase 4,Not Applicable
37 Anesthetics, General Phase 4,Not Applicable
38 Anesthetics, Dissociative Phase 4
39 Excitatory Amino Acid Antagonists Phase 4
40 Narcotics Phase 4,Phase 3,Phase 2,Not Applicable
41 Anesthetics, Intravenous Phase 4,Not Applicable
42 Excitatory Amino Acids Phase 4
43 Analgesics, Opioid Phase 4,Phase 3,Phase 2,Not Applicable
44 Pharmaceutical Solutions Phase 4,Not Applicable
45 Autonomic Agents Phase 4,Phase 3,Not Applicable
46 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Not Applicable
47 Antiemetics Phase 4,Phase 3,Not Applicable
48 Gastrointestinal Agents Phase 4,Phase 3,Not Applicable
49 HIV Protease Inhibitors Phase 4
50
protease inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 194)
# Name Status NCT ID Phase Drugs
1 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Completed NCT01292252 Phase 4
2 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
3 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
4 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
5 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
6 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
7 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
10 BIO4 Clinical Case Study: Cervical Spine Active, not recruiting NCT03077204 Phase 4
11 Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection Enrolling by invitation NCT03166761 Phase 4 Dexamethasone;Triamcinolone Acetonide
12 Liposomal Bupivacaine in One-level Instrumented Posterior Spinal Fusion Not yet recruiting NCT03745040 Phase 4 Liposomal bupivacaine
13 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
14 Efficacy of Using Solum IV and BMC With GFC in TLIF Withdrawn NCT03223701 Phase 4
15 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Unknown status NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
16 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
17 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
18 The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Completed NCT00506558 Phase 3
19 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
20 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
21 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
22 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Recruiting NCT03327272 Phase 3 Methylprednisolone;Saline
23 Peri-Incisional Drug Injection in Lumbar Spine Surgery Not yet recruiting NCT03513445 Phase 3 Morphine;Epinephrine;naropin
24 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
25 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
26 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
27 Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain Completed NCT00587626 Phase 2
28 Effect of Cervical Collar in Cervical Radicular Pain. Completed NCT00395798 Phase 2
29 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
30 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
31 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
32 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
33 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
34 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
35 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
36 Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery Terminated NCT02276911 Phase 2 Ibuprofen
37 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
38 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
39 Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory Unknown status NCT02199405 Not Applicable
40 Diabetes and Glycosylation in Cervical Spondylosis Unknown status NCT02758899
41 Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant Unknown status NCT02819089 Not Applicable Dexmedetomidine
42 Baxter: Actifuse SHAPE vs DBX in ACC Unknown status NCT02005081 Not Applicable
43 Decompressive Cervical Surgery and Hypertension Unknown status NCT02016768
44 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284 Not Applicable
45 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
46 Balance Chiropractic Therapy for Cervical Spondylotic Radiculopathy Unknown status NCT02705131 Not Applicable
47 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
48 Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study Unknown status NCT02873182 Not Applicable
49 Supine vs. Upright Weight Bearing MRI in the Evaluation of Patients With Lumbar Spondylolisthesis Unknown status NCT02958241 Not Applicable
50 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379 Not Applicable

Search NIH Clinical Center for Spondylosis

Cochrane evidence based reviews: spondylosis

Genetic Tests for Spondylosis

Anatomical Context for Spondylosis

MalaCards organs/tissues related to Spondylosis:

41
Spinal Cord, Bone, Brain, Bone Marrow, Heart, Kidney, Prostate

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylosis:

19
Vertebral Column

Publications for Spondylosis

Articles related to Spondylosis:

(show top 50) (show all 790)
# Title Authors Year
1
Effectiveness of percutaneous neuromuscular electrical stimulation for neck pain relief in patients with cervical spondylosis. ( 29952946 )
2018
2
Diagnosis and Incidence of Spondylosis and Cervical Disc Disorders in the University Clinical Hospital in Olsztyn, in Years 2011-2015. ( 29770333 )
2018
3
What is the superior surgical strategy for bi-level cervical spondylosis-anterior cervical disc replacement or anterior cervical decompression and fusion?: A meta-analysis from 11 studies. ( 29595628 )
2018
4
Change in Low Back Movement Patterns After Neurosurgical Intervention for Lumbar Spondylosis. ( 29482826 )
2018
5
Clinical Effects of Posterior Longitudinal Ligament Removal and Wide Anterior Cervical Corpectomy for Spondylosis. ( 29510291 )
2018
6
Wet cupping therapy improves local blood perfusion and analgesic effects in patients with nerve-root type cervical spondylosis. ( 29340888 )
2018
7
Prevalence of and risk factors for Modic change in patients with symptomatic cervical spondylosis: an observational study. ( 29491718 )
2018
8
Modified Laminoplasty for Degenerative Cervical Spondylosis: The Technique of Floating Laminoplasty. ( 29643725 )
2018
9
Risk of acute coronary syndrome in patients with cervical spondylosis. ( 29518745 )
2018
10
Reply to "Use of radiologic indicators to predict difficult laryngoscopy in patients with cervical spondylosis". ( 29675834 )
2018
11
Atypical symptoms in patients with cervical spondylosis: Comparison of the treatment effect of different surgical approaches. ( 29768345 )
2018
12
Myelopathy after cervical disc arthroplasty due to progression of spondylosis at the index level: case report. ( 29393833 )
2018
13
Exploration about changes of IL-10, NF-I_B and MMP-3 in a rat model of cervical spondylosis. ( 29197741 )
2018
14
Changes and significance of inflammatory cytokines in a rat model of cervical spondylosis. ( 29387194 )
2018
15
Alterations in Cortical Thickness and Subcortical Volume are Associated With Neurological Symptoms and Neck Pain in Patients With Cervical Spondylosis. ( 29548020 )
2018
16
Risk factors for non-fusion segment disease after anterior cervical spondylosis surgery: a retrospective study with long-term follow-up of 171 patients. ( 29394936 )
2018
17
Association between Cervical Spondylosis and Migraine: A Nationwide Retrospective Cohort Study. ( 29587400 )
2018
18
Use of radiological indicators to predict difficult laryngoscopy in patients with cervical spondylosis. ( 29708587 )
2018
19
The effectiveness of anterior cervical decompression and fusion for the relief of dizziness in patients with cervical spondylosis: a multicentre prospective cohort study. ( 29305455 )
2018
20
Ossification of posterior longitudinal ligament and cervical spondylosis: Same cause - Same treatment. ( 29755229 )
2018
21
Apparent C8-T1 radiculopathy with hand weakness due to mid-cervical spondylosis. ( 29097135 )
2018
22
The Influence of Depression on Health Care Expenditures Among Adults with Spondylosis, Intervertebral Disc Disorders, and Other Back Problems in the United States. ( 30445578 )
2018
23
Association of Depression and Cervical Spondylosis: A Nationwide Retrospective Propensity Score-Matched Cohort Study. ( 30366474 )
2018
24
A Convenient Non-harm Cervical Spondylosis Intelligent Identity method based on Machine Learning. ( 30479349 )
2018
25
Difference of dynamic morphometric changes between in patients with ossification of posterior longitudinal ligament and patients with cervical spondylosis: Assessed by Cervical dynamic MRI. ( 30528528 )
2018
26
The Option of Motion Preservation in Cervical Spondylosis: Cervical Disc Arthroplasty Update. ( 30545210 )
2018
27
Role of hybrid construct in cervical spondylosis. ( 30545645 )
2018
28
Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. ( 29354237 )
2018
29
Radiologic indicators for prediction of difficult laryngoscopy in patients with cervical spondylosis. ( 29388207 )
2018
30
Comparison of sagittal parameters for anterior cervical discectomy and fusion, hybrid surgery, and total disc replacement for three levels of cervical spondylosis. ( 29550690 )
2018
31
Resting-State Functional Magnetic Resonance Imaging Connectivity of the Brain Is Associated with Altered Sensorimotor Function in Patients with Cervical Spondylosis. ( 30092474 )
2018
32
A Hybrid Dynamic Stabilization and Fusion System in Multilevel Lumbar Spondylosis. ( 30126265 )
2018
33
Association of Arrhythmia in Patients with Cervical Spondylosis: A Nationwide Population-Based Cohort Study. ( 30142924 )
2018
34
Risk of posterior circulation stroke in patients with cervical spondylosis: A nationwide, population-based study. ( 30172083 )
2018
35
Clinical efficacy of glucosamine hydrochloride tablets in the treatment of cervical spondylosis. ( 30203748 )
2018
36
Clinical effect of cervical paravertebral nerve block combined with Mailuoning and Angelica sinensis in treatment of nerve-root type cervical spondylosis. ( 30203752 )
2018
37
The prevalence and associated factors of symptomatic cervical Spondylosis in Chinese adults: a community-based cross-sectional study. ( 30205836 )
2018
38
Cervical instability in cervical spondylosis patients : Significance of the radiographic index method for evaluation. ( 30255359 )
2018
39
Motor neurone disease-associated neck pain misdiagnosed as cervical spondylosis: A case report and literature review. ( 30257805 )
2018
40
Expert's comment concerning Grand Rounds case entitled "Double crush syndrome caused by cervical spondylosis and vertebral artery loop" by Young Joon Rho et al. (Eur Spine J; 2017: doi:10.1007/s00586-017-5064-0). ( 30382425 )
2018
41
Comparison of high-intensity laser therapy and combination of ultrasound treatment and transcutaneous nerve stimulation in patients with cervical spondylosis: a randomized controlled trial. ( 30443883 )
2018
42
Reliability and validity of CODA motion analysis system for measuring cervical range of motion in patients with cervical spondylosis and anterior cervical fusion. ( 29285065 )
2017
43
Comments for radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 28761504 )
2017
44
Surgical interventions for cervical spondylosis due to ossification of posterior longitudinal ligament: A meta-analysis. ( 28816942 )
2017
45
Complications and Mortality Following One to Two-Level Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 80 Years of Age. ( 28441681 )
2017
46
Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents. ( 28061494 )
2017
47
Vertical spinal instability and cervical spondylosis: Is it focal or multisegmental? ( 29021665 )
2017
48
The association between multiple sclerosis and spondylosis: When and why. ( 28629570 )
2017
49
Clinical and Radiological Analysis of Bryan Cervical Artificial Disc Replacement for "Skip" Multi-Segment Cervical Spondylosis: Long-Term Follow-Up Results. ( 29101314 )
2017
50
Comparison between zero-profile spacer and plate with cage in the treatment of single level cervical spondylosis. ( 29171978 )
2017

Variations for Spondylosis

Expression for Spondylosis

Search GEO for disease gene expression data for Spondylosis.

Pathways for Spondylosis

GO Terms for Spondylosis

Cellular components related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ENO2 HTRA1 IL1B KL PTH S100B

Biological processes related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.43 HMGCR KL WRN
2 negative regulation of MAP kinase activity GO:0043407 9.37 HMGCR IL1B
3 positive regulation of bone mineralization GO:0030501 9.32 KL PTH
4 response to vitamin D GO:0033280 9.16 IL1B PTH
5 response to ethanol GO:0045471 9.13 HMGCR IL1B PTH
6 mammary gland branching involved in pregnancy GO:0060745 8.62 ESR1 VDR

Molecular functions related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 8.96 ESR1 VDR
2 vitamin D binding GO:0005499 8.62 KL VDR

Sources for Spondylosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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