MCID: SPN020
MIFTS: 51

Spondylosis

Categories: Bone diseases, Neuronal diseases

Aliases & Classifications for Spondylosis

MalaCards integrated aliases for Spondylosis:

Name: Spondylosis 12 44 15 73
Spondylogenic Compression of Thoracic Spinal Cord 12
Spondylogenic Compression of Lumbar Spinal Cord 12
Thoracic or Lumbar Spondylosis with Myelopathy 12
Lumbosacral Spondylosis Without Myelopathy 12
Lumbar Spondylosis with Myelopathy 12
Spondylosis with Myelopathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2247
ICD10 33 M47 M47.9
ICD9CM 35 721.9
MeSH 44 D055009
UMLS 73 C0038019

Summaries for Spondylosis

Disease Ontology : 12 An bone structure disease that involves degeneration between vertebra located in vertebral column.

MalaCards based summary : Spondylosis, also known as spondylogenic compression of thoracic spinal cord, is related to head injury and osteoporosis. An important gene associated with Spondylosis is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways/superpathways are Parathyroid hormone synthesis, secretion and action and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. The drugs Dexamethasone and Pregabalin have been mentioned in the context of this disorder. Affiliated tissues include vertebral column, spinal cord and bone, and related phenotypes are growth/size/body region and cardiovascular system

Wikipedia : 76 Spondylosis is a broad term meaning degeneration of the spinal column from any cause. In the more narrow... more...

Related Diseases for Spondylosis

Diseases related to Spondylosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 head injury 30.5 ENO2 S100B
2 osteoporosis 26.3 ESR1 HMGCR IL1B KL PTH VDR
3 spondylosis, cervical 12.1
4 central cord syndrome 11.2
5 cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 11.1
6 cervicitis 11.0
7 barre-lieou syndrome 10.9
8 spastic paraplegia 25 10.9
9 intracranial cysts 10.7 ENO2 S100B
10 bednar tumor 10.7 ENO2 S100B
11 epithelioid malignant peripheral nerve sheath tumor 10.7 ENO2 S100B
12 middle cerebral artery infarction 10.7 ENO2 S100B
13 ossifying fibromyxoid tumor 10.7 ENO2 S100B
14 melanotic neuroectodermal tumor 10.7 ENO2 S100B
15 pineocytoma 10.7 ENO2 S100B
16 papillary ependymoma 10.7 ENO2 S100B
17 subependymal giant cell astrocytoma 10.7 ENO2 S100B
18 clear cell adenoma 10.7 PTH S100B
19 granular cell tumor 10.7 ENO2 S100B
20 meningeal melanocytoma 10.6 ENO2 S100B
21 olfactory neuroblastoma 10.6 ENO2 S100B
22 cerebral primitive neuroectodermal tumor 10.6 ENO2 S100B
23 traumatic brain injury 10.6 ENO2 S100B
24 cloacogenic carcinoma 10.6 ENO2 PTH
25 optic nerve glioma 10.6 ENO2 S100B
26 acute mountain sickness 10.5 ENO2 S100B
27 extraosseous ewing's sarcoma 10.5 ENO2 S100B
28 calciphylaxis 10.5 PTH VDR
29 hypercalcemia, infantile, 1 10.5 PTH VDR
30 pilomatrixoma 10.5 ENO2 S100B
31 campylobacteriosis 10.5 IL1B VDR
32 cervical clear cell adenocarcinoma 10.5 ENO2 ESR1
33 syringoma 10.4 ESR1 S100B
34 mixed cell type cancer 10.4 ENO2 ESR1
35 brain injury 10.4 ENO2 S100B
36 vulvar vestibulitis syndrome 10.4 ESR1 IL1B
37 secondary hyperparathyroidism of renal origin 10.4 PTH VDR
38 parathyroid gland disease 10.4 PTH VDR
39 ganglioglioma 10.4 ENO2 S100B
40 renal osteodystrophy 10.4 PTH VDR
41 hidradenocarcinoma 10.4 ESR1 S100B
42 endometrial disease 10.4 ESR1 IL1B
43 vaginitis 10.3 ESR1 IL1B
44 secondary progressive multiple sclerosis 10.3 ENO2 S100B
45 idiopathic hypercalciuria 10.3 IL1B VDR
46 protrusio acetabuli 10.3 ESR1 VDR
47 endometritis 10.3 ESR1 IL1B
48 neurilemmoma 10.3 ENO2 S100B
49 prostatitis 10.2 IL1B VDR
50 uterine anomalies 10.2 ESR1 IL1B

Comorbidity relations with Spondylosis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Spondylosis:



Diseases related to Spondylosis

Symptoms & Phenotypes for Spondylosis

MGI Mouse Phenotypes related to Spondylosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.1 ENO2 ESR1 KL HELLS PTH HMGCR
2 cardiovascular system MP:0005385 10.02 IL1B ESR1 KL PTH HTRA1 VDR
3 homeostasis/metabolism MP:0005376 9.97 IL1B ESR1 KL HELLS PTH HMGCR
4 craniofacial MP:0005382 9.93 IL1B ENO2 KL PTH VDR WRN
5 endocrine/exocrine gland MP:0005379 9.91 ESR1 KL HELLS PTH VDR WRN
6 hematopoietic system MP:0005397 9.91 IL1B ESR1 KL HELLS PTH VDR
7 immune system MP:0005387 9.8 IL1B ESR1 KL HELLS PTH VDR
8 integument MP:0010771 9.7 ESR1 KL HELLS S100B IL1B VDR
9 limbs/digits/tail MP:0005371 9.43 ESR1 KL HELLS PTH VDR WRN
10 skeleton MP:0005390 9.23 ESR1 KL HELLS PTH HTRA1 IL1B

Drugs & Therapeutics for Spondylosis

Drugs for Spondylosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 50-02-2 5743
2
Pregabalin Approved, Illicit, Investigational Phase 4,Not Applicable 148553-50-8 5486971
3
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
4
Triamcinolone Approved, Vet_approved Phase 4,Not Applicable 124-94-7 31307
5
Ketamine Approved, Vet_approved Phase 4,Phase 2 6740-88-1 3821
6
Menthol Approved Phase 4,Not Applicable 2216-51-5 16666
7
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
8 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable
9 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable
10 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
11 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
12 Hormones Phase 4,Phase 3,Not Applicable
13 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Not Applicable
14 BB 1101 Phase 4,Phase 2,Not Applicable
15 Dexamethasone acetate Phase 4,Phase 2,Not Applicable 1177-87-3
16 Anti-Anxiety Agents Phase 4
17 Anticonvulsants Phase 4
18 calcium channel blockers Phase 4
19 Calcium, Dietary Phase 4
20 Psychotropic Drugs Phase 4
21 Tranquilizing Agents Phase 4
22 Anesthetics, Local Phase 4,Phase 2
23 Anti-Arrhythmia Agents Phase 4
24 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
25 Diuretics, Potassium Sparing Phase 4
26 glucocorticoids Phase 4,Phase 3,Not Applicable
27 Hormone Antagonists Phase 4,Phase 3,Not Applicable
28 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
29 Immunosuppressive Agents Phase 4,Not Applicable
30 Sodium Channel Blockers Phase 4
31 triamcinolone acetonide Phase 4,Not Applicable
32 Triamcinolone diacetate Phase 4,Not Applicable
33 Triamcinolone hexacetonide Phase 4,Not Applicable
34 Analgesics, Opioid Phase 4,Not Applicable
35 Anesthetics, Dissociative Phase 4
36 Anesthetics, General Phase 4,Not Applicable
37 Anesthetics, Intravenous Phase 4,Not Applicable
38 Excitatory Amino Acid Antagonists Phase 4
39 Excitatory Amino Acids Phase 4
40 Narcotics Phase 4,Phase 2,Not Applicable
41 Antiemetics Phase 4,Phase 3,Not Applicable
42 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Not Applicable
43 Autonomic Agents Phase 4,Phase 3,Not Applicable
44 Gastrointestinal Agents Phase 4,Phase 3,Not Applicable
45 HIV Protease Inhibitors Phase 4
46
protease inhibitors Phase 4
47
Dexmedetomidine Approved, Vet_approved Phase 2, Phase 3,Not Applicable 113775-47-6 68602 5311068
48
Methylprednisolone Approved, Vet_approved Phase 3,Not Applicable 83-43-2 6741
49
Prednisolone Approved, Vet_approved Phase 3,Not Applicable 50-24-8 5755
50 Adrenergic Agents Phase 2, Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 182)
# Name Status NCT ID Phase Drugs
1 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
2 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
3 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
4 Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia Completed NCT01325493 Phase 4 Ketamine;Normal Saline
5 Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis Completed NCT00000409 Phase 4
6 BIO4 Clinical Case Study: Cervical Spine Recruiting NCT03077204 Phase 4
7 Effect of Pregabalin on Immediate Post-operative and Longterm Pain Recruiting NCT02464813 Phase 4 Pregabalin;Sugar pill;Oxycodone
8 Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis Recruiting NCT01921530 Phase 4
9 Minuteman Spinal Fusion Implant Versus Surgical Decompression for Lumbar Spinal Stenosis Recruiting NCT01455805 Phase 4
10 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
11 Particulate Corticosteroid Versus Non-particulate Corticosteroid for Sacroiliac Joint Injection Enrolling by invitation NCT03166761 Phase 4 Dexamethasone;Triamcinolone Acetonide
12 Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device Terminated NCT00095095 Phase 4
13 Efficacy of Using Solum IV and BMC With GFC in TLIF Withdrawn NCT03223701 Phase 4
14 Total Facet Arthroplasty System®(TFAS®) Clinical Trial Unknown status NCT00418197 Phase 3
15 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
16 The CSM Trial: A Multicenter Study Comparing Ventral to Dorsal Surgery for Cervical Spondylotic Myelopathy Completed NCT00506558 Phase 3
17 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
18 Greenwich Lumbar Stenosis SLIP Study Completed NCT00109213 Phase 3
19 Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis Completed NCT00405691 Phase 3
20 Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion Recruiting NCT02854904 Phase 2, Phase 3 Dexmedetomidine intervention;Placebo
21 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Not yet recruiting NCT03327272 Phase 3 Methylprednisolone;Saline
22 Peri-Incisional Drug Injection in Lumbar Spine Surgery Not yet recruiting NCT03513445 Phase 3 Morphine;Epinephrine;naropin
23 A Clinical Study of the Dynesys(R) Spinal System Terminated NCT00759057 Phase 3
24 Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798902 Phase 1, Phase 2
25 Pilot Study to Assess Safety/Prelimary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery Unknown status NCT00798239 Phase 1, Phase 2
26 Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain Completed NCT00587626 Phase 2
27 Effect of Cervical Collar in Cervical Radicular Pain. Completed NCT00395798 Phase 2
28 Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Completed NCT01106417 Phase 2
29 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Completed NCT01097486 Phase 2
30 Safety and Preliminary Efficacy Study of NeoFuse in Subjects Requiring Lumbar Interbody Fusion Completed NCT00996073 Phase 2
31 Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF) Completed NCT00549913 Phase 1, Phase 2
32 Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery Recruiting NCT02276911 Phase 2 Ibuprofen
33 Safety and Preliminary Effectiveness of NVD-001 for the Treatment of Low Grade Degenerative Lumbar Spondylolisthesis Recruiting NCT03100032 Phase 1, Phase 2
34 Transverse Abdominis Plane Block for Anterior Approach Spine Surgery Recruiting NCT02884440 Phase 2 TAP block ropivacaine;TAP block placebo;General anesthesia
35 Safety Study of Mesenchymal Stem Cells and Spinal Fusion Active, not recruiting NCT01552707 Phase 1, Phase 2
36 CopiOs Posterolateral Fusion Procedure Terminated NCT01123850 Phase 2
37 Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion Withdrawn NCT00810212 Phase 1, Phase 2
38 Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory Unknown status NCT02199405 Not Applicable
39 Diabetes and Glycosylation in Cervical Spondylosis Unknown status NCT02758899
40 Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant Unknown status NCT02819089 Not Applicable Dexmedetomidine
41 Baxter: Actifuse SHAPE vs DBX in ACC Unknown status NCT02005081 Not Applicable
42 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion Unknown status NCT01292252 Not Applicable
43 Efficacy Study of Acupuncture to Treat Spinal Pain Unknown status NCT01909284 Not Applicable
44 Physical Therapy Management in Degenerative Lumbar Diseases and Osteoporosis Unknown status NCT01703403
45 Balance Chiropractic Therapy for Cervical Spondylotic Radiculopathy Unknown status NCT02705131 Not Applicable
46 Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain Unknown status NCT01918943
47 Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine Unknown status NCT01224379 Not Applicable
48 Post-market Study of the TOPS™ System Unknown status NCT02234154 Not Applicable
49 Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Unknown status NCT02171169
50 Post-market Study of the TOPS™ System Unknown status NCT01933607 Not Applicable

Search NIH Clinical Center for Spondylosis

Cochrane evidence based reviews: spondylosis

Genetic Tests for Spondylosis

Anatomical Context for Spondylosis

The Foundational Model of Anatomy Ontology organs/tissues related to Spondylosis:

19
Vertebral Column

MalaCards organs/tissues related to Spondylosis:

41
Spinal Cord, Bone, Bone Marrow, Testes, Brain, Cortex, Dorsal Root Ganglion

Publications for Spondylosis

Articles related to Spondylosis:

(show top 50) (show all 646)
# Title Authors Year
1
Effectiveness of percutaneous neuromuscular electrical stimulation for neck pain relief in patients with cervical spondylosis. ( 29952946 )
2018
2
Diagnosis and Incidence of Spondylosis and Cervical Disc Disorders in the University Clinical Hospital in Olsztyn, in Years 2011-2015. ( 29770333 )
2018
3
What is the superior surgical strategy for bi-level cervical spondylosis-anterior cervical disc replacement or anterior cervical decompression and fusion?: A meta-analysis from 11 studies. ( 29595628 )
2018
4
Change in Low Back Movement Patterns After Neurosurgical Intervention for Lumbar Spondylosis. ( 29482826 )
2018
5
Clinical Effects of Posterior Longitudinal Ligament Removal and Wide Anterior Cervical Corpectomy for Spondylosis. ( 29510291 )
2018
6
Wet cupping therapy improves local blood perfusion and analgesic effects in patients with nerve-root type cervical spondylosis. ( 29340888 )
2018
7
Prevalence of and risk factors for Modic change in patients with symptomatic cervical spondylosis: an observational study. ( 29491718 )
2018
8
Modified Laminoplasty for Degenerative Cervical Spondylosis: The Technique of Floating Laminoplasty. ( 29643725 )
2018
9
Risk of acute coronary syndrome in patients with cervical spondylosis. ( 29518745 )
2018
10
Atypical symptoms in patients with cervical spondylosis: Comparison of the treatment effect of different surgical approaches. ( 29768345 )
2018
11
Myelopathy after cervical disc arthroplasty due to progression of spondylosis at the index level: case report. ( 29393833 )
2018
12
Exploration about changes of IL-10, NF-I_B and MMP-3 in a rat model of cervical spondylosis. ( 29197741 )
2018
13
Changes and significance of inflammatory cytokines in a rat model of cervical spondylosis. ( 29387194 )
2018
14
Alterations in Cortical Thickness and Subcortical Volume are Associated With Neurological Symptoms and Neck Pain in Patients With Cervical Spondylosis. ( 29548020 )
2018
15
Risk factors for non-fusion segment disease after anterior cervical spondylosis surgery: a retrospective study with long-term follow-up of 171 patients. ( 29394936 )
2018
16
Association between Cervical Spondylosis and Migraine: A Nationwide Retrospective Cohort Study. ( 29587400 )
2018
17
Use of radiological indicators to predict difficult laryngoscopy in patients with cervical spondylosis. ( 29708587 )
2018
18
The effectiveness of anterior cervical decompression and fusion for the relief of dizziness in patients with cervical spondylosis: a multicentre prospective cohort study. ( 29305455 )
2018
19
Ossification of posterior longitudinal ligament and cervical spondylosis: Same cause - Same treatment. ( 29755229 )
2018
20
Apparent C8-T1 radiculopathy with hand weakness due to mid-cervical spondylosis. ( 29097135 )
2018
21
Comparison of sagittal parameters for anterior cervical discectomy and fusion, hybrid surgery, and total disc replacement for three levels of cervical spondylosis. ( 29550690 )
2018
22
Novel Genetic Variants Associated with Lumbar Spondylosis in Koreans : A Genome-Wide Association Study. ( 29354237 )
2018
23
Radiologic indicators for prediction of difficult laryngoscopy in patients with cervical spondylosis. ( 29388207 )
2018
24
Reliability and validity of CODA motion analysis system for measuring cervical range of motion in patients with cervical spondylosis and anterior cervical fusion. ( 29285065 )
2017
25
Comments for radiological study of C3-C4 level surgical cases of cervical spondylosis. ( 28761504 )
2017
26
Surgical interventions for cervical spondylosis due to ossification of posterior longitudinal ligament: A meta-analysis. ( 28816942 )
2017
27
Complications and Mortality Following One to Two-Level Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 80 Years of Age. ( 28441681 )
2017
28
Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents. ( 28061494 )
2017
29
Vertical spinal instability and cervical spondylosis: Is it focal or multisegmental? ( 29021665 )
2017
30
The association between multiple sclerosis and spondylosis: When and why. ( 28629570 )
2017
31
Clinical and Radiological Analysis of Bryan Cervical Artificial Disc Replacement for "Skip" Multi-Segment Cervical Spondylosis: Long-Term Follow-Up Results. ( 29101314 )
2017
32
Comparison between zero-profile spacer and plate with cage in the treatment of single level cervical spondylosis. ( 29171978 )
2017
33
[Clinical analysis of cervical posterior internal fixation titanium plate and silk suspension internal fixation cervical spondylosis]. ( 28241724 )
2017
34
Double crush syndrome caused by cervical spondylosis and vertebral artery loop. ( 28508239 )
2017
35
Mid-term efficacy and safety of cervical disc arthroplasty versus fusion in cervical spondylosis: A systematic review and meta-analysis. ( 28357067 )
2017
36
Relationship between the small cervical vertebral body and the morbidity of cervical spondylosis. ( 28767572 )
2017
37
Effectiveness of acupuncture in the management of cervical spondylosis: a meta-analysis. ( 29254308 )
2017
38
Efficacy of cortico/cancellous composite allograft in treatment of cervical spondylosis. ( 28816974 )
2017
39
Anterior Cervical Spondylosis Surgical Interventions are Associated with Improved Lordosis and Neurological Outcomes at Latest Follow up: A Meta-analysis. ( 28667278 )
2017
40
Evaluation of a granulated formula for the nerve root type and vertebral artery type of cervical spondylosis: a multicenter, single-blind, randomized, controlled, phase a8c clinical trial. ( 29960291 )
2017
41
Patients' beliefs about diagnosis and treatment of cervical spondylosis with radiculopathy. ( 29063271 )
2017
42
Neck circumference to inter-incisor gap ratio: a new predictor of difficult laryngoscopy in cervical spondylosis patients. ( 28376741 )
2017
43
Abnormal central motor conduction at the upper but not lower limbs correlates with severe cervical spondylosis: discussion of an unexpected observation. ( 28382220 )
2017
44
Safety and Efficacy Study of an Ozone Laser Combined Therapy Using Puncture Needle in the Treatment of Patients With Cervical Spondylosis. ( 28525469 )
2017
45
ACDF vs TDR for patients with cervical spondylosis - an 8A year follow up study. ( 29183306 )
2017
46
Shikani Optical Stylet versus Macintosh Laryngoscope for Intubation in Patients Undergoing Surgery for Cervical Spondylosis: A Randomized Controlled Trial. ( 28139512 )
2017
47
Surgical treatment of multilevel cervical spondylosis in patients with or without a history of syringomyelia. ( 28190207 )
2017
48
The Effectiveness of Cervical Spondylosis Therapy with Saunders Traction Device and High-Intensity Laser Therapy: A Randomized Controlled Trial. ( 28104903 )
2017
49
Difference in prevalence of cervical spondylosis in Muslim population who perform NAMAZ > 4 time a day who perform NAMAZ infrequently. ( 27728680 )
2016
50
[Acupuncture and moxibustion based on meridian differentiation for cervical spondylosis radiculopathy:a randomized controlled trial]. ( 29231452 )
2016

Variations for Spondylosis

Expression for Spondylosis

Search GEO for disease gene expression data for Spondylosis.

Pathways for Spondylosis

GO Terms for Spondylosis

Cellular components related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ENO2 HTRA1 IL1B KL PTH S100B

Biological processes related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of MAP kinase activity GO:0043407 9.26 HMGCR IL1B
2 positive regulation of bone mineralization GO:0030501 9.16 KL PTH
3 aging GO:0007568 9.13 HMGCR KL WRN
4 mammary gland branching involved in pregnancy GO:0060745 8.62 ESR1 VDR

Molecular functions related to Spondylosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 8.96 ESR1 VDR
2 vitamin D binding GO:0005499 8.62 KL VDR

Sources for Spondylosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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