MCID: SPT005
MIFTS: 50

Spotted Fever

Categories: Infectious diseases, Rare diseases, Skin diseases

Aliases & Classifications for Spotted Fever

Summaries for Spotted Fever

Disease Ontology : 12 A primary bacterial infectious disease that results in infection, located in endothelial cell of artery or located in endothelial cell of vein, has material basis in Rickettsia, which is transmitted by ticks and mites. The infection has symptom fever, has symptom headache, has symptom fatigue, has symptom muscle aches, and has symptom maculopapular or petechial rash. A distinctive eschar (blackened or crusted skin) may develop at the site of a tick bite.

MalaCards based summary : Spotted Fever, also known as spotted fevers, is related to astrakhan spotted fever and flinders island spotted fever. An important gene associated with Spotted Fever is HTRA1 (HtrA Serine Peptidase 1), and among its related pathways/superpathways are ERK Signaling and PEDF Induced Signaling. The drugs carbamide peroxide and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and endothelial, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 74 A spotted fever is a type of tick-borne disease which presents on the skin. They are all caused by... more...

Related Diseases for Spotted Fever

Diseases related to Spotted Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 524)
# Related Disease Score Top Affiliating Genes
1 astrakhan spotted fever 34.3 CD40LG CCL5
2 flinders island spotted fever 34.2 CS AFF2
3 spotted fever rickettsiosis 33.9 TNF IL10 IFNG IDO1 CTLA4 CCL5
4 japanese spotted fever 33.5 PPP1R14A CD40LG AFF2
5 queensland tick typhus 33.1 PLEKHG4 CS
6 israeli tick typhus 32.9 PPP1R14A PLEKHG4
7 rocky mountain spotted fever 32.1 SPTBN2 PPP1R14A PLEKHG4 CS CD40LG AFF2
8 african tick-bite fever 32.1 VWF TNF IL10 IFNG CS CD40LG
9 boutonneuse fever 31.1 THBD SPTBN2 PPP1R14A PLEKHG4 CS CD40LG
10 exanthem 31.0 TNF IL10 F2 CTLA4 CD40LG
11 indian tick typhus 31.0 PPP1R14A PLEKHG4 CD40LG AFF2
12 disseminated intravascular coagulation 30.9 VWF TNF THBD IL10 F2
13 pulmonary edema 30.7 TNF IL10 F2
14 endemic typhus 30.6 SPTBN2 PPP1R14A PLEKHG4 HTRA1 CS AFF2
15 ehrlichiosis 30.6 IL10 CD40LG CASP3
16 vasculitis 30.6 VWF TNF THBD CTLA4 CD40LG
17 conjunctivitis 30.6 TNF IL10 IFNG CXCL9
18 appendicitis 30.5 TNF IL10 IFNG
19 arthritis 30.5 TNF IL10 IFNG CTLA4 CCL5
20 adult respiratory distress syndrome 30.5 TNF THBD IL10 F2
21 meningoencephalitis 30.5 TNF IL10 CD40LG CCL5
22 toxic shock syndrome 30.4 TNF IL10 IFNG CD40LG
23 dengue disease 30.3 TNF CD40LG CCL5
24 common cold 30.2 TNF IL10 CCL5
25 uveitis 30.2 TNF IL10 IFNG CXCL10 CTLA4
26 q fever 30.2 TNF IL10 IFNG CXCL9 CD40LG CCL5
27 pericarditis 30.2 TNF IFNG CD40LG
28 japanese encephalitis 30.2 TNF CXCL10 CCL5
29 bacterial meningitis 30.2 TNF IL10 IFNG
30 keratitis, hereditary 30.2 TNF IL10 CXCL9
31 respiratory failure 30.2 TNF THBD IL10 F2 CXCL10 CCL5
32 leptospirosis 30.2 TNF IL10 IFNG F2 CD40LG
33 reactive arthritis 30.1 TNF IL10 IFNG
34 visceral leishmaniasis 30.1 TNF IL10 IFNG CXCL9
35 bronchopneumonia 30.1 TNF IL10 CD40LG
36 alopecia 30.1 TNF IFNG HTRA1 CTLA4
37 scrub typhus 30.1 TNF IL10 IFNG IDO1 CD40LG AFF2
38 aseptic meningitis 30.1 TNF IL10 IFNG CD40LG
39 purpura 30.0 VWF TNF THBD IL10 F2 CD40LG
40 hemophagocytic lymphohistiocytosis 30.0 TNF IL10 IFNG CTLA4
41 typhoid fever 30.0 TNF IFNG HTRA1 F2 CD40LG
42 measles 30.0 TNF IFNG CD40LG CCL5
43 myocarditis 29.9 TNF IL10 IFNG CTLA4 CD40LG CASP3
44 meningitis 29.9 TNF IL10 IFNG CD40LG CCL5
45 proteasome-associated autoinflammatory syndrome 1 29.9 TNF IL10 IFNG CXCL10 CCL5
46 orchitis 29.9 TNF IL10 CD40LG
47 panuveitis 29.9 TNF IL10 CD40LG
48 bacterial infectious disease 29.8 TNF IL10 IFNG CXCL9 CD40LG
49 lymphadenitis 29.8 TNF IL10 IFNG CXCL9 CASP3
50 thrombophlebitis 29.8 VWF F2 CD40LG

Graphical network of the top 20 diseases related to Spotted Fever:



Diseases related to Spotted Fever

Symptoms & Phenotypes for Spotted Fever

GenomeRNAi Phenotypes related to Spotted Fever according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.77 BAX CASP3 CD40LG F2 IL10 PLEKHG4
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.77 BAX CASP3 CD40LG F2 IL10 PLEKHG4

MGI Mouse Phenotypes related to Spotted Fever:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.21 CASP3 CD40LG CTLA4 CXCL10 F2 HTRA1
2 hematopoietic system MP:0005397 10.18 BAX CASP3 CCL5 CD40LG CTLA4 CXCL10
3 homeostasis/metabolism MP:0005376 10.13 BAX CASP3 CD40LG CS CTLA4 CXCL10
4 immune system MP:0005387 10.07 BAX CASP3 CCL5 CD40LG CTLA4 CXCL10
5 digestive/alimentary MP:0005381 10.01 CASP3 CTLA4 F2 IFNG IL10 THBD
6 nervous system MP:0003631 9.9 BAX CASP3 CD40LG CXCL10 F2 IFNG
7 respiratory system MP:0005388 9.56 BAX CASP3 CTLA4 F2 IFNG IL10
8 skeleton MP:0005390 9.32 BAX CASP3 CD40LG CTLA4 F2 HTRA1

Drugs & Therapeutics for Spotted Fever

Drugs for Spotted Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
carbamide peroxide Approved 124-43-6
2 Immunologic Factors
3 Protective Agents
4 Insect Repellents
5 Eucalyptus
6 Antibiotics, Antitubercular
7 Anti-Infective Agents
8 Antitubercular Agents
9 Anti-Bacterial Agents
10 Antibodies
11 Immunoglobulins
12 Immunoglobulin G
13 Immunoglobulin A
14 Immunoglobulin M

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Laboratory Diagnosis of of Rickettsial and Rickettsia-like Diseases Unknown status NCT01137175
2 Phase I Study for Positive IgM Antibody Detection in New Diagnostic Test Kit for for Acute Phase Infection Unknown status NCT01646411
3 A Single Group Trial to Determine the Complete Protection Time of an Insect Repellent Formulation Containing 30% Citriodiol® (Oil of Lemon Eucalyptus) Against Three Species of Ticks. Completed NCT03708120
4 The Impact of C-reactive Protein Testing on Antibiotic Prescription in Febrile Patients Attending Primary Care in Low-resource Settings Completed NCT02758821
5 Background Seroprevalence of Rickettsial Infections in Myanmar Not yet recruiting NCT03847870
6 Lyme Test Indication Combinations (LyTIC) Study Terminated NCT03201042

Search NIH Clinical Center for Spotted Fever

Genetic Tests for Spotted Fever

Anatomical Context for Spotted Fever

MalaCards organs/tissues related to Spotted Fever:

40
Testes, Skin, Endothelial, Salivary Gland, T Cells, Kidney, Liver

Publications for Spotted Fever

Articles related to Spotted Fever:

(show top 50) (show all 3273)
# Title Authors PMID Year
1
Detection of a novel spotted fever group rickettsia in Amblyomma parvum ticks (Acari: Ixodidae) from Argentina. 61 54
17768597 2007
2
Emerging tick-borne pathogens in the Nordic countries: A clinical and laboratory follow-up study of high-risk tick-bitten individuals. 61
31631052 2020
3
A rickettsia infection from Saudi Arabia. 61
31689527 2020
4
Diversity of Rickettsia in Ticks Collected in Abruzzi and Molise Regions (Central Italy). 61
31847276 2019
5
Japanese spotted fever. 61
31851356 2019
6
Community-based prevention of epidemic Rocky Mountain spotted fever among minority populations in Sonora, Mexico, using a One Health approach. 61
31819997 2019
7
Clinical case of spotted fever group rickettsiae. 61
31541702 2019
8
Spatial and temporal trends of Mediterranean spotted fever in Spain, 2005-2015. 61
31839472 2019
9
Fatal Brazilian Spotted Fever Associated with Dogs and Amblyomma aureolatum Ticks, Brazil, 2013. 61
31742533 2019
10
Distribution and Ecological Drivers of Spotted Fever Group Rickettsia in Asia. 61
30993545 2019
11
Seroprevalence of spotted fever group rickettsiae in canines along the United States-Mexico border. 61
31441594 2019
12
Hospital based serological evidence of rickettsial diseases and assessment diagnostic tests of pyrexia of unknown origin. 61
31805833 2019
13
Human Parasitism by Amblyomma parkeri Ticks Infected with Candidatus Rickettsia paranaensis, Brazil. 61
31742531 2019
14
Insight into diversity of bacteria belonging to the order Rickettsiales in 9 arthropods species collected in Serbia. 61
31822714 2019
15
Epidemiological aspects of Rickettsia parkeri in the Atlantic forest biome of Espírito Santo state, Brazil. 61
31707006 2019
16
Exposure of dogs to Rickettsia spp. in Costa Rica: Risk factors for PCR-positive ectoparasites and seropositivity. 61
31489383 2019
17
Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever. 61
31516114 2019
18
In vitro evaluation of minimum inhibitory concentration of several antibacterial agents against Rickettsia japonica using a plaque reduction assay system. 61
31186196 2019
19
A Metabolic Dependency for Host Isoprenoids in the Obligate Intracellular Pathogen Rickettsia parkeri Underlies a Sensitivity to the Statin Class of Host-Targeted Therapeutics. 61
31722991 2019
20
Spotted fever group rickettsiae canine serosurveillance near the US-Mexico border in California. 61
31769616 2019
21
Knowledge and prevention of tickborne diseases among Hispanic and non-Hispanic residents of Maryland and Virginia. 61
31478316 2019
22
Prevalence of Spotted Fever Group Rickettsia in North-Eastern Poland. 61
31496338 2019
23
An optimized five-color/seven-parameter flow cytometry panel for immunophenotyping guinea pig peripheral blood lymphocytes. 61
31682796 2019
24
First description of Coxiella burnetii and Rickettsia spp. infection and molecular detection of piroplasma co-infecting horses in Xinjiang Uygur Autonomous Region, China. 61
31759172 2019
25
Case report: A patient coinfected by Borrelia burgdorferi sensu lato and spotted fever group Rickettsiae in Urumqi, China. 61
31725662 2019
26
Minimal Duration of Tick Attachment Sufficient for Transmission of Infectious Rickettsia rickettsii (Rickettsiales: Rickettsiaceae) by Its Primary Vector Dermacentor variabilis (Acari: Ixodidae): Duration of Rickettsial Reactivation in the Vector Revisited. 61
31687749 2019
27
Molecular Detection of Rickettsia felis and Rickettsia bellii in Mosquitoes. 61
31306085 2019
28
Detection of Antibodies to Spotted Fever Group Rickettsiae and Arboviral Coinfections in Febrile Individuals in 2014-2015 in Southern Coastal Ecuador. 61
31549616 2019
29
[Investigation and research on ticks carrying spotted fever group rickettsia in the border area of Tumen River Basin]. 61
31683400 2019
30
Integrated tick control on a farm with the presence of capybaras in a Brazilian spotted fever endemic region. 61
31778531 2019
31
The Dynamics of Ticks and Capybaras in a Residential Park Area in Southeastern Brazil: Implications for the Risk of Rickettsia rickettsii Infection. 61
31135286 2019
32
Japanese Spotted Fever with Hemophagocytic Lymphohistiocytosis. 61
31645532 2019
33
Two for the price of one: Co-infection with Rickettsia bellii and spotted fever group Rickettsia in Amblyomma (Acari: Ixodidae) ticks recovered from wild birds in Brazil. 61
31402227 2019
34
Rapid and Highly Sensitive DNA Flow Technology Platform to Detect Tick-Borne Bacterial Pathogens in Clinical Samples. 61
31638480 2019
35
[Spotted fever in Argentina. Description of two clinical cases]. 61
30928146 2019
36
Serosurvey of Rickettsia spp. in cats from a Brazilian spotted fever-endemic area. 61
31721931 2019
37
Diagnosis of spotted fever group Rickettsia infections: the Asian perspective. 61
31587667 2019
38
COYOTES (CANIS LATRANS) IN ARIZONA, USA, EXHIBIT IMMUNE AND GENETIC EVIDENCE OF RICKETTSIAL INFECTIONS. 61
31658430 2019
39
Serological evidence of Borrelia circulation among blood donors in the São Paulo state, Brazil. 61
31468639 2019
40
Expanding Recognition of Rickettsia parkeri Rickettsiosis in Southern Arizona, 2016-2017. 61
31638478 2019
41
Molecular Detection of Spotted Fever Group Rickettsiae (Rickettsiales: Rickettsiaceae) in Dermacentor variabilis (Acari: Ixodidae) Collected Along the Platte River in South Central Nebraska. 61
31576408 2019
42
Integrated tick control on a farm with the presence of capybaras in a Brazilian spotted fever endemic region. 61
31800889 2019
43
Molecular epidemiology and phylogeny of spotted fever group Rickettsia in camels (Camelus dromedarius) and their infesting ticks from Tunisia. 61
31626722 2019
44
A human case of spotted fever caused by Rickettsia parkeri strain Atlantic rainforest and its association to the tick Amblyomma ovale. 61
31604442 2019
45
A putative novel strain of Ehrlichia infecting Amblyomma tigrinum associated with Pampas fox (Lycalopex gymnocercus) in Esteros del Iberá ecoregion, Argentina. 61
31711730 2019
46
A novel TaqMan assay to detect Rickettsia 364D, the etiologic agent of Pacific Coast tick fever. 61
31666366 2019
47
Prevalence and molecular characterization of Rickettsia spp. in questing ticks from north-western Spain. 61
31655926 2019
48
Phenology of Amblyomma sculptum in a degraded area of Atlantic rainforest in north-eastern Brazil. 61
31331735 2019
49
Multistate Survey of American Dog Ticks (Dermacentor variabilis) for Rickettsia Species. 61
30942664 2019
50
HLA-B27 spondyloarthritis and spotted fever rickettsiosis: case-based review. 61
31134290 2019

Variations for Spotted Fever

Expression for Spotted Fever

Search GEO for disease gene expression data for Spotted Fever.

Pathways for Spotted Fever

Pathways related to Spotted Fever according to GeneCards Suite gene sharing:

(show all 40)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.8 TNF PPP1R14A IL10 CXCL9 CXCL10 CD40LG
2
Show member pathways
13.56 TNF PPP1R14A IL10 IFNG F2 CXCL9
3
Show member pathways
13.38 TNF IL10 CXCL9 CXCL10 CD40LG CCL5
4
Show member pathways
13.27 VWF TNF SPTBN2 IL10 IFNG CXCL10
5
Show member pathways
13.26 TNF IL10 CXCL9 CXCL10 CD40LG CCL5
6
Show member pathways
12.99 TNF IL10 IFNG CXCL9 CXCL10 CCL5
7
Show member pathways
12.8 TNF IFNG CXCL10 CCL5 CASP3 BAX
8 12.76 TNF IFNG CCL5 CASP3 BAX
9
Show member pathways
12.69 TNF IL10 IFNG CXCL9 CTLA4 CD40LG
10
Show member pathways
12.58 TNF IL10 IFNG CTLA4 CD40LG
11
Show member pathways
12.5 TNF IL10 IFNG F2 CXCL9 BAX
12
Show member pathways
12.3 TNF IFNG CXCL10 CASP3
13
Show member pathways
12.3 TNF IFNG F2 CCL5
14
Show member pathways
12.29 TNF IL10 CXCL9 CXCL10 CCL5
15 12.27 TNF F2 CASP3 BAX
16 12.22 TNF CD40LG CASP3 BAX
17
Show member pathways
12.21 TNF IL10 IFNG CD40LG CASP3
18 12.18 TNF IL10 IFNG CASP3 BAX
19 12.17 TNF IFNG CASP3 BAX
20 12.07 TNF IL10 IFNG IDO1 CXCL10 CTLA4
21 12 TNF IFNG CXCL10 CASP3
22 11.96 TNF CXCL10 CCL5 CASP3
23 11.89 TNF IL10 IFNG CASP3
24 11.88 TNF THBD CASP3 BAX
25 11.84 TNF IFNG CTLA4 CCL5
26 11.76 TNF IL10 IFNG
27 11.73 TNF IL10 CASP3
28 11.72 TNF THBD IL10 IFNG
29
Show member pathways
11.63 TNF IFNG CD40LG
30 11.53 TNF IFNG BAX
31 11.5 TNF IFNG BAX
32
Show member pathways
11.43 TNF IFNG CTLA4 CD40LG CASP3
33 11.37 IFNG CXCL9 CXCL10
34 11.37 TNF IL10 IFNG CD40LG
35 11.31 TNF IL10 CXCL10 CCL5
36 11.3 TNF CASP3 BAX
37 11.24 TNF IL10 IFNG
38 11.13 TNF IL10 IFNG IDO1
39 10.95 TNF IL10 IFNG CXCL9 CXCL10 CCL5
40 10.88 TNF IL10 CXCL9 CXCL10 CD40LG CCL5

GO Terms for Spotted Fever

Cellular components related to Spotted Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.85 VWF TNF IL10 IFNG HTRA1 F2
2 external side of plasma membrane GO:0009897 9.43 TNF F2 CXCL9 CXCL10 CTLA4 CD40LG
3 extracellular space GO:0005615 9.36 TNF THBD SPTBN2 IL10 IFNG HTRA1

Biological processes related to Spotted Fever according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 10 TNF IDO1 CTLA4 CASP3 BAX
2 cytokine-mediated signaling pathway GO:0019221 9.97 TNF IL10 CXCL10 CCL5 CASP3
3 cellular response to lipopolysaccharide GO:0071222 9.91 TNF IL10 CXCL9 CXCL10
4 neutrophil chemotaxis GO:0030593 9.86 CXCL9 CXCL10 CCL5
5 chemokine-mediated signaling pathway GO:0070098 9.85 CXCL9 CXCL10 CCL5
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.84 TNF IFNG CCL5
7 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.83 F2 CXCL9 CXCL10
8 cellular response to organic cyclic compound GO:0071407 9.83 TNF CCL5 CASP3
9 response to virus GO:0009615 9.83 TNF IFNG CXCL10 CCL5
10 regulation of insulin secretion GO:0050796 9.82 TNF IFNG CCL5
11 response to glucocorticoid GO:0051384 9.82 TNF IL10 CASP3
12 apoptotic signaling pathway GO:0097190 9.81 TNF CASP3 BAX
13 positive regulation of neuron apoptotic process GO:0043525 9.8 TNF CASP3 BAX
14 inflammatory response GO:0006954 9.8 TNF IL10 IDO1 CXCL9 CXCL10 CD40LG
15 hemostasis GO:0007599 9.79 VWF THBD F2
16 extrinsic apoptotic signaling pathway GO:0097191 9.76 TNF IFNG BAX
17 negative regulation of T cell proliferation GO:0042130 9.75 IL10 IDO1 CTLA4
18 response to wounding GO:0009611 9.73 VWF F2 CASP3 BAX
19 response to lipopolysaccharide GO:0032496 9.72 THBD IL10 IDO1 CXCL10 CASP3
20 negative regulation of activated T cell proliferation GO:0046007 9.69 IDO1 CASP3
21 positive regulation of interleukin-12 production GO:0032735 9.69 IFNG IDO1 CD40LG
22 positive regulation of chemokine biosynthetic process GO:0045080 9.68 TNF IFNG
23 negative regulation of amyloid-beta clearance GO:1900222 9.68 TNF IFNG
24 negative regulation of fibrinolysis GO:0051918 9.68 THBD F2
25 positive regulation of MHC class II biosynthetic process GO:0045348 9.68 IL10 IFNG
26 response to salt stress GO:0009651 9.67 TNF BAX
27 negative regulation of T cell apoptotic process GO:0070233 9.66 IDO1 CCL5
28 negative regulation of platelet activation GO:0010544 9.66 THBD F2
29 endothelial cell apoptotic process GO:0072577 9.63 TNF IL10
30 positive regulation of T cell apoptotic process GO:0070234 9.63 IDO1 CCL5
31 leukocyte chemotaxis GO:0030595 9.63 IL10 CXCL9 CXCL10
32 negative regulation of cytokine secretion involved in immune response GO:0002740 9.61 TNF IL10
33 regulation of immunoglobulin secretion GO:0051023 9.59 TNF CD40LG
34 positive regulation of amyloid-beta formation GO:1902004 9.58 TNF IFNG CASP3
35 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.56 TNF IFNG
36 receptor biosynthetic process GO:0032800 9.55 TNF IL10
37 positive regulation of B cell apoptotic process GO:0002904 9.54 IL10 BAX
38 negative regulation of B cell proliferation GO:0030889 9.54 IL10 CTLA4 CASP3
39 positive regulation of vitamin D biosynthetic process GO:0060557 9.49 TNF IFNG
40 positive regulation of nitrogen compound metabolic process GO:0051173 9.48 TNF IFNG
41 positive regulation of JAK-STAT cascade GO:0046427 9.46 TNF IL10 F2 CCL5
42 positive regulation of release of sequestered calcium ion into cytosol GO:0051281 9.26 F2 CXCL9 CXCL10 BAX
43 immune response GO:0006955 9.23 TNF IL10 IFNG CXCL9 CXCL10 CTLA4

Molecular functions related to Spotted Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CXCL9 CXCL10 CCL5
2 cytokine activity GO:0005125 9.17 TNF IL10 IFNG CXCL9 CXCL10 CD40LG
3 CXCR3 chemokine receptor binding GO:0048248 8.96 CXCL9 CXCL10

Sources for Spotted Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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