MCID: SQM005
MIFTS: 24

Squamous Papillomatosis

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Squamous Papillomatosis

MalaCards integrated aliases for Squamous Papillomatosis:

Name: Squamous Papillomatosis 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:7532
NCIt 50 C9009
SNOMED-CT 68 82049002
UMLS 72 C1378340

Summaries for Squamous Papillomatosis

MalaCards based summary : Squamous Papillomatosis is related to papilloma and squamous cell papilloma. An important gene associated with Squamous Papillomatosis is IFNA2 (Interferon Alpha 2), and among its related pathways/superpathways are Jak-Stat Signaling Pathway (sino) and all-trans-Retinoic Acid Mediated Apoptosis. Affiliated tissues include trachea.

Related Diseases for Squamous Papillomatosis

Diseases related to Squamous Papillomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 papilloma 10.6
2 squamous cell papilloma 10.4
3 lymphomatoid granulomatosis 10.3 IFNA2 IFNA1
4 cryoglobulinemia, familial mixed 10.3 IFNA2 IFNA1
5 discoid lupus erythematosus 10.2 IFNA2 IFNA1
6 herpangina 10.2 IFNA2 IFNA1
7 in situ carcinoma 10.2
8 fungal esophagitis 10.1 ATP4A ATP12A
9 gastroduodenal crohn's disease 10.1 ATP4A ATP12A
10 diclofenac allergy 10.1 ATP4A ATP12A
11 neonatal candidiasis 10.1 ATP4A ATP12A
12 photoallergic dermatitis 10.1 ATP4A ATP12A
13 gastrointestinal neuroendocrine benign tumor 10.1 ATP4A ATP12A
14 aspiration pneumonitis 10.1 ATP4A ATP12A
15 toxic megacolon 10.1 ATP4A ATP12A
16 granulomatous gastritis 10.1 ATP4A ATP12A
17 gastric antral vascular ectasia 10.1 ATP4A ATP12A
18 acute laryngitis 10.1 ATP4A ATP12A
19 laryngitis 10.1 ATP4A ATP12A
20 gastric neuroendocrine neoplasm 10.1 ATP4A ATP12A
21 esophageal candidiasis 10.1 ATP4A ATP12A
22 duodenitis 10.1 ATP4A ATP12A
23 active peptic ulcer disease 10.1 ATP4A ATP12A
24 rumination disorder 10.1 ATP4A ATP12A
25 dyskinesia of esophagus 10.1 ATP4A ATP12A
26 peptic esophagitis 10.1 ATP4A ATP12A
27 capillary disease 10.1 ATP4A ATP12A
28 bile reflux 10.1 ATP4A ATP12A
29 ischemic neuropathy 10.1 ATP4A ATP12A
30 bladder calculus 10.1 ATP4A ATP12A
31 congenital disorder of deglycosylation 10.1 ATP4A ATP12A
32 anismus 10.1 ATP4A ATP12A
33 dysphagia 10.1
34 hernia, hiatus 10.1 ATP4A ATP12A
35 postsurgical hypothyroidism 10.1 ATP4A ATP12A
36 esophageal atresia/tracheoesophageal fistula 10.1 ATP4A ATP12A
37 lymphocytic colitis 10.1 ATP4A ATP12A
38 clostridium difficile colitis 10.1 ATP4A ATP12A
39 esophagitis, eosinophilic, 1 10.1 ATP4A ATP12A
40 diarrhea 1, secretory chloride, congenital 10.1 ATP4A ATP12A
41 laryngeal tuberculosis 10.1 ATP4A ATP12A
42 microscopic colitis 10.1 ATP4A ATP12A
43 chronic intestinal vascular insufficiency 10.1 ATP4A ATP12A
44 hairy cell leukemia 10.1 IFNA2 IFNA1
45 esophagus adenocarcinoma 10.0 ATP4A ATP12A
46 eosinophilic gastritis 10.0 ATP4A ATP12A
47 chronic laryngitis 10.0 ATP4A ATP12A
48 superior mesenteric artery syndrome 10.0 ATP4A ATP12A
49 esophageal varix 10.0 ATP4A ATP12A
50 pancreatic steatorrhea 10.0 ATP4A ATP12A

Graphical network of the top 20 diseases related to Squamous Papillomatosis:



Diseases related to Squamous Papillomatosis

Symptoms & Phenotypes for Squamous Papillomatosis

Drugs & Therapeutics for Squamous Papillomatosis

Search Clinical Trials , NIH Clinical Center for Squamous Papillomatosis

Genetic Tests for Squamous Papillomatosis

Anatomical Context for Squamous Papillomatosis

MalaCards organs/tissues related to Squamous Papillomatosis:

41
Trachea

Publications for Squamous Papillomatosis

Articles related to Squamous Papillomatosis:

(show all 35)
# Title Authors PMID Year
1
Diffuse Esophageal Squamous Papillomatosis Covering the Entire Esophagus. 38
29627426 2018
2
Treatment of Diffuse Esophageal Squamous Papillomatosis with Cryotherapy. 38
27694865 2016
3
Esophageal squamous papillomatosis. 38
27271553 2016
4
A Rare Cause of Dysphagia: Squamous Papillomatosis of the Esophagus. 38
26435069 2016
5
Oesophageal papillomatosis, not amenable to endoscopic therapies, treated with oesophagectomy. 38
24789149 2014
6
Endoscopic mucosal resection of esophageal squamous papillomatosis. 38
23166898 2012
7
A case of esophageal squamous papillomatosis. 38
22707902 2012
8
[Extensive squamous papillomatosis of the oesophagus with malignant transformation of squamous epithelium]. 38
22069046 2011
9
Esophageal squamous papillomatosis with dysplasia. Is there a role of balloon-based radiofrequency ablation therapy? 38
19902876 2009
10
Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient. 38
18648834 2009
11
Esophageal papillomatosis complicated by squamous cell carcinoma. 38
19543571 2009
12
'HPV vulvitis' revisited: frequent and persistent detection of novel epidermodysplasia verruciformis-associated HPV genotypes. 38
18251739 2008
13
Prevalence and genotyping of human papillomavirus infection in women with vulvodynia. 38
17653888 2007
14
Unique expression of human papilloma virus type 5 and type 16 in esophageal squamous cell carcinoma-a case report. 38
16952290 2006
15
Esophageal squamous papillomatosis. 38
16215437 2005
16
Squamous papillomatosis of the bilateral nasal cavities. 38
15942156 2005
17
Photodynamic therapy and endoscopic metal stent placement for esophageal papillomatosis associated with squamous cell carcinoma. 38
15230738 2004
18
Vulvar malignant melanoma associated with human papillomavirus DNA: report of two cases and review of literature. 38
12140440 2002
19
Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b. 38
11401080 2001
20
Treatment of recurrent conjunctival papillomatosis with mitomycin C. 38
10577537 1999
21
Vulvar and vaginal colposcopic pictures of human papillomavirus infection. 38
7664773 1995
22
Adult type squamous papillomatosis of larynx with extension to trachea and bronchial tree: a report of two cases. 38
8299046 1993
23
[Squamous papillomatosis of the left main bronchus and trachea: a case report]. 38
8361114 1993
24
Vulvar squamous papillomatosis and human papillomavirus infection. A polymerase chain reaction study. 38
8397492 1993
25
Human papillomavirus infection of the female genital tract: correlation of HPV DNA with cytologic, colposcopic, and natural history findings. 38
1319903 1992
26
Evidence of human papillomavirus deoxyribonucleic acid in vulvar squamous papillomatosis. 38
1848835 1991
27
[Vulvar pruriginous squamous papillomatosis]. 38
1965223 1990
28
Subsets of vulvodynia. 38
3050074 1988
29
Benign squamous papillomatosis: case report. 38
3428897 1987
30
Pruritic vulvar squamous papillomatosis: evidence for human papillomavirus etiology. 38
2995892 1985
31
Papillomas of the tracheobronchial tree with malignant degeneration. 38
699664 1978
32
Oesophageal papillomata in the child. 38
701985 1978
33
Malignant squamous papillomatosis of the mastoid. 38
691094 1978
34
Squamous papillomatosis of the trachea and bronchi. 38
5350717 1969
35
Squamous papillomatosis of the stomach, a new pathologic entity: report of a case. 38
14018854 1962

Variations for Squamous Papillomatosis

Expression for Squamous Papillomatosis

Search GEO for disease gene expression data for Squamous Papillomatosis.

Pathways for Squamous Papillomatosis

Pathways related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.9 IFNA2 IFNA1
2 10.26 IFNA2 IFNA1

GO Terms for Squamous Papillomatosis

Cellular components related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 IFNA2 IFNA1 ATP4A AFM

Biological processes related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.55 ATP4A ATP12A
2 B cell differentiation GO:0030183 9.54 IFNA2 IFNA1
3 type I interferon signaling pathway GO:0060337 9.52 IFNA2 IFNA1
4 humoral immune response GO:0006959 9.51 IFNA2 IFNA1
5 potassium ion import across plasma membrane GO:1990573 9.49 ATP4A ATP12A
6 response to exogenous dsRNA GO:0043330 9.48 IFNA2 IFNA1
7 B cell proliferation GO:0042100 9.46 IFNA2 IFNA1
8 ATP hydrolysis coupled proton transport GO:0015991 9.43 ATP4A ATP12A
9 T cell activation involved in immune response GO:0002286 9.4 IFNA2 IFNA1
10 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.37 IFNA2 IFNA1
11 natural killer cell activation involved in immune response GO:0002323 9.32 IFNA2 IFNA1
12 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
13 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
14 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
15 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 9.26 IFNA2 IFNA1
2 type I interferon receptor binding GO:0005132 9.16 IFNA2 IFNA1
3 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP4A ATP12A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Squamous Papillomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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