MCID: SQM005
MIFTS: 27

Squamous Papillomatosis

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Squamous Papillomatosis

MalaCards integrated aliases for Squamous Papillomatosis:

Name: Squamous Papillomatosis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7532
NCIt 50 C9009
SNOMED-CT 67 82049002
UMLS 70 C1378340

Summaries for Squamous Papillomatosis

MalaCards based summary : Squamous Papillomatosis is related to barrett esophagus and papilloma. An important gene associated with Squamous Papillomatosis is AFM (Afamin), and among its related pathways/superpathways are Cytoskeletal Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include breast, kidney and appendix.

Related Diseases for Squamous Papillomatosis

Diseases related to Squamous Papillomatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 356)
# Related Disease Score Top Affiliating Genes
1 barrett esophagus 29.5 KRT7 KRT20 ATP4A ATP12A
2 papilloma 10.6
3 squamous cell papilloma 10.4
4 corneal intraepithelial neoplasm 10.4 IFNA2 IFNA1
5 vagus nerve disease 10.4 ATP4A ATP12A
6 necrotizing gastritis 10.3 ATP4A ATP12A
7 scalp dermatosis 10.3 ATP4A ATP12A
8 hemangioma of intra-abdominal structure 10.3 ATP4A ATP12A
9 acquired gastric outlet stenosis 10.3 ATP4A ATP12A
10 lingual goiter 10.3 ATP4A ATP12A
11 displacement of cardia through esophageal hiatus 10.3 ATP4A ATP12A
12 lymphomatoid granulomatosis 10.3 IFNA2 IFNA1
13 follicular mucinosis 10.3 KRT15 IFNA2
14 bacterial esophagitis 10.3 ATP4A ATP12A
15 cascade stomach 10.3 ATP4A ATP12A
16 benzylpenicillin allergy 10.3 ATP4A ATP12A
17 median arcuate ligament syndrome 10.3 ATP4A ATP12A
18 afferent loop syndrome 10.3 ATP4A ATP12A
19 angiodysplasia of intestine 10.3 ATP4A ATP12A
20 angiodysplasia 10.3 ATP4A ATP12A
21 granulomatous gastritis 10.3 ATP4A ATP12A
22 laryngeal tuberculosis 10.3 ATP4A ATP12A
23 fungal esophagitis 10.3 ATP4A ATP12A
24 dieulafoy lesion 10.3 ATP4A ATP12A
25 fibroepithelial basal cell carcinoma 10.3 PHLDA1 KRT20
26 esophagus melanoma 10.3 ATP4A ATP12A
27 cefuroxime allergy 10.3 ATP4A ATP12A
28 emphysematous cholecystitis 10.3 ATP4A ATP12A
29 gastric gastrinoma 10.3 ATP4A ATP12A
30 cryoglobulinemia, familial mixed 10.3 IFNA2 IFNA1
31 superior mesenteric artery syndrome 10.3 ATP4A ATP12A
32 pneumatosis cystoides intestinalis 10.3 ATP4A ATP12A
33 chronic laryngitis 10.3 ATP4A ATP12A
34 laryngitis 10.3 ATP4A ATP12A
35 peptic ulcer perforation 10.3 ATP4A ATP12A
36 viral laryngitis 10.3 ATP4A ATP12A
37 gastroduodenal crohn's disease 10.3 ATP4A ATP12A
38 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3 ATP4A ATP12A
39 central nervous system origin vertigo 10.3 ATP4A ATP12A
40 rumination disorder 10.3 ATP4A ATP12A
41 internal hemorrhoid 10.3 ATP4A ATP12A
42 acute laryngitis 10.3 ATP4A ATP12A
43 gastroduodenitis 10.3 ATP4A ATP12A
44 chronic intestinal vascular insufficiency 10.3 ATP4A ATP12A
45 barbiturate abuse 10.3 ATP4A ATP12A
46 inverted follicular keratosis 10.3 PTGER4 PHLDA1
47 duodenal gastrinoma 10.3 ATP4A ATP12A
48 internal hordeolum 10.3 IFNA2 IFNA1
49 gastric dilatation 10.3 ATP4A ATP12A
50 gastric hemangioma 10.3 ATP4A ATP12A

Graphical network of the top 20 diseases related to Squamous Papillomatosis:



Diseases related to Squamous Papillomatosis

Symptoms & Phenotypes for Squamous Papillomatosis

Drugs & Therapeutics for Squamous Papillomatosis

Search Clinical Trials , NIH Clinical Center for Squamous Papillomatosis

Genetic Tests for Squamous Papillomatosis

Anatomical Context for Squamous Papillomatosis

MalaCards organs/tissues related to Squamous Papillomatosis:

40
Breast, Kidney, Appendix, Thymus, Liver, Lung, Thyroid

Publications for Squamous Papillomatosis

Articles related to Squamous Papillomatosis:

(show all 38)
# Title Authors PMID Year
1
Diffuse Esophageal Squamous Papillomatosis: A Rare Disease Associated with Acanthosis Nigricans and Tripe Palms. 61
33568969 2020
2
A case of esophageal carcinoma due to esophageal squamous papillomatosis. 61
32492647 2020
3
Successful Treatment of Extensive Esophageal Squamous Papillomatosis With Cryotherapy. 61
31620505 2019
4
Diffuse Esophageal Squamous Papillomatosis Covering the Entire Esophagus. 61
29627426 2018
5
Treatment of Diffuse Esophageal Squamous Papillomatosis with Cryotherapy. 61
27694865 2016
6
Esophageal squamous papillomatosis. 61
27271553 2016
7
A Rare Cause of Dysphagia: Squamous Papillomatosis of the Esophagus. 61
26435069 2016
8
Oesophageal papillomatosis, not amenable to endoscopic therapies, treated with oesophagectomy. 61
24789149 2014
9
Endoscopic mucosal resection of esophageal squamous papillomatosis. 61
23166898 2012
10
A case of esophageal squamous papillomatosis. 61
22707902 2012
11
[Extensive squamous papillomatosis of the oesophagus with malignant transformation of squamous epithelium]. 61
22069046 2011
12
Esophageal squamous papillomatosis with dysplasia. Is there a role of balloon-based radiofrequency ablation therapy? 61
19902876 2009
13
Esophageal papillomatosis complicated by squamous cell carcinoma. 61
19543571 2009
14
Surgery and topic cidofovir for nasal squamous papillomatosis in HIV+ patient. 61
18648834 2009
15
'HPV vulvitis' revisited: frequent and persistent detection of novel epidermodysplasia verruciformis-associated HPV genotypes. 61
18251739 2008
16
Prevalence and genotyping of human papillomavirus infection in women with vulvodynia. 61
17653888 2007
17
Unique expression of human papilloma virus type 5 and type 16 in esophageal squamous cell carcinoma-a case report. 61
16952290 2006
18
Esophageal squamous papillomatosis. 61
16215437 2005
19
Squamous papillomatosis of the bilateral nasal cavities. 61
15942156 2005
20
Photodynamic therapy and endoscopic metal stent placement for esophageal papillomatosis associated with squamous cell carcinoma. 61
15230738 2004
21
Vulvar malignant melanoma associated with human papillomavirus DNA: report of two cases and review of literature. 61
12140440 2002
22
Successful treatment of severe respiratory papillomatosis with intravenous cidofovir and interferon alpha-2b. 61
11401080 2001
23
Treatment of recurrent conjunctival papillomatosis with mitomycin C. 61
10577537 1999
24
Vulvar and vaginal colposcopic pictures of human papillomavirus infection. 61
7664773 1995
25
Adult type squamous papillomatosis of larynx with extension to trachea and bronchial tree: a report of two cases. 61
8299046 1993
26
[Squamous papillomatosis of the left main bronchus and trachea: a case report]. 61
8361114 1993
27
Vulvar squamous papillomatosis and human papillomavirus infection. A polymerase chain reaction study. 61
8397492 1993
28
Human papillomavirus infection of the female genital tract: correlation of HPV DNA with cytologic, colposcopic, and natural history findings. 61
1319903 1992
29
Evidence of human papillomavirus deoxyribonucleic acid in vulvar squamous papillomatosis. 61
1848835 1991
30
[Vulvar pruriginous squamous papillomatosis]. 61
1965223 1990
31
Subsets of vulvodynia. 61
3050074 1988
32
Benign squamous papillomatosis: case report. 61
3428897 1987
33
Pruritic vulvar squamous papillomatosis: evidence for human papillomavirus etiology. 61
2995892 1985
34
Papillomas of the tracheobronchial tree with malignant degeneration. 61
699664 1978
35
Oesophageal papillomata in the child. 61
701985 1978
36
Malignant squamous papillomatosis of the mastoid. 61
691094 1978
37
Squamous papillomatosis of the trachea and bronchi. 61
5350717 1969
38
Squamous papillomatosis of the stomach, a new pathologic entity: report of a case. 61
14018854 1962

Variations for Squamous Papillomatosis

Expression for Squamous Papillomatosis

Search GEO for disease gene expression data for Squamous Papillomatosis.

Pathways for Squamous Papillomatosis

Pathways related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.75 TOR1A KRT7 KRT20 EPCAM
2 11.4 MME IFNA2 CEACAM5
3 10.67 MME IFNA2 EPCAM

GO Terms for Squamous Papillomatosis

Cellular components related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.17 TOR1A MME KRT7 KRT15 EPCAM CEACAM5

Biological processes related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell activation involved in immune response GO:0002286 9.43 IFNA2 IFNA1
2 cornification GO:0070268 9.43 KRT7 KRT20 KRT15
3 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.4 IFNA2 IFNA1
4 cellular sodium ion homeostasis GO:0006883 9.37 ATP4A ATP12A
5 natural killer cell activation involved in immune response GO:0002323 9.32 IFNA2 IFNA1
6 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
7 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Squamous Papillomatosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 type I interferon receptor binding GO:0005132 9.26 IFNA2 IFNA1
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
3 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
4 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Squamous Papillomatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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