MCID: STL001
MIFTS: 42

St. Louis Encephalitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for St. Louis Encephalitis

MalaCards integrated aliases for St. Louis Encephalitis:

Name: St. Louis Encephalitis 12 60 3 15 17
Encephalitis, St. Louis 45 74
Neuroinvasive St. Louis Encephalitis Virus Infection 12
Saint Louis Encephalitis 60

Characteristics:

Orphanet epidemiological data:

60
st. louis encephalitis
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:



External Ids:

Disease Ontology 12 DOID:10845
ICD9CM 36 062.3
MeSH 45 D004674
SNOMED-CT 69 10429004
ICD10 34 A83.3
MESH via Orphanet 46 D004674
ICD10 via Orphanet 35 A83.3
UMLS via Orphanet 75 C0014060
Orphanet 60 ORPHA83484
UMLS 74 C0014060

Summaries for St. Louis Encephalitis

CDC : 3 Saint Louis encephalitis (SLE) is a viral disease spread to people by the bite of an infected mosquito. Most people infected with SLE virus have no apparent illness. Initial symptoms of those who become ill include fever, headache, nausea, vomiting, and tiredness. Severe neuroinvasive disease (often involving encephalitis, an inflammation of the brain) occurs more commonly in older adults. In rare cases, long-term disability or death can result. There are no vaccines to prevent nor medications to treat SLE. Care is based on symptoms. You can reduce your risk of infection with SLE virus by using insect repellent, wearing long-sleeved shirts and long pants, and taking steps to control mosquitoes indoors and outdoors.

MalaCards based summary : St. Louis Encephalitis, also known as encephalitis, st. louis, is related to murray valley encephalitis and encephalitis, and has symptoms including headache, coma and disorientation. An important gene associated with St. Louis Encephalitis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways is all-trans-Retinoic Acid Mediated Apoptosis. Affiliated tissues include brain, brain and thyroid.

Disease Ontology : 12 A viral infectious disease that results in inflammation located in brain, has material basis in St. Louis encephalitis virus, which is transmitted by Culex mosquitoes. The infection has symptom headache, has symptom high fever, has symptom neck stiffness, has symptom stupor, has symptom disorientation, has symptom coma, has symptom tremors, has symptom convulsions and has symptom spastic paralysis.

Wikipedia : 77 Saint Louis encephalitis is a disease caused by the mosquito borne Saint Louis encephalitis virus. Saint... more...

Related Diseases for St. Louis Encephalitis

Diseases related to St. Louis Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 murray valley encephalitis 30.2 ERVW-1 SNORA73B
2 encephalitis 11.4
3 west nile virus 10.7
4 yellow fever 10.5
5 dengue virus 10.4
6 eastern equine encephalitis 10.4
7 shipyard eye 10.4
8 keratoconjunctivitis 10.4
9 poliomyelitis 10.3
10 louping ill 10.2
11 western equine encephalitis 10.2
12 rabies 10.2
13 venezuelan equine encephalitis 10.2
14 stomatitis 10.2
15 noonan syndrome 3 10.1
16 conjunctival disease 10.1 IFNA2 RNASE3
17 malaria 10.1
18 cataract 10.1
19 dengue disease 10.1
20 chikungunya 10.1
21 tick-borne encephalitis 10.1
22 japanese encephalitis 10.1
23 sarcoma 10.1
24 cauda equina syndrome 10.1
25 vascular disease 10.1
26 vaccinia 10.1
27 polyradiculopathy 10.1
28 subacute thyroiditis 10.1
29 thyroiditis 10.1
30 influenza 10.1
31 vernal conjunctivitis 10.0 POMC RNASE3
32 common cold 10.0 IFNA2 RNASE3
33 rhinitis 9.9 POMC RNASE3
34 noonan syndrome 1 9.4 CFAP410 ERVW-1 RNASE1

Graphical network of the top 20 diseases related to St. Louis Encephalitis:



Diseases related to St. Louis Encephalitis

Symptoms & Phenotypes for St. Louis Encephalitis

Symptoms:

12
  • headache
  • coma
  • disorientation
  • tremors
  • stupor
  • spastic paralysis
  • neck stiffness
  • convulsions
  • high fever

Drugs & Therapeutics for St. Louis Encephalitis

Search Clinical Trials , NIH Clinical Center for St. Louis Encephalitis

Cochrane evidence based reviews: encephalitis, st. louis

Genetic Tests for St. Louis Encephalitis

Anatomical Context for St. Louis Encephalitis

The Foundational Model of Anatomy Ontology organs/tissues related to St. Louis Encephalitis:

20
Brain

MalaCards organs/tissues related to St. Louis Encephalitis:

42
Brain, Thyroid, Testes, Kidney, Pituitary, Salivary Gland, Eye

Publications for St. Louis Encephalitis

Articles related to St. Louis Encephalitis:

(show top 50) (show all 427)
# Title Authors Year
1
Vector Competence for West Nile Virus and St. Louis Encephalitis Virus (Flavivirus) of Three Tick Species of the Genus Amblyomma (Acari: Ixodidae). ( 30887949 )
2019
2
First detection of Mansonia titillans (Diptera: Culicidae) infected with St. Louis encephalitis virus (Flaviviridae: Flavivirus) and Bunyamwera serogroup (Peribunyaviridae: Orthobunyavirus) in Argentina. ( 30408293 )
2018
3
Reemergence of St. Louis Encephalitis Virus in the Americas. ( 30457961 )
2018
4
St. Louis Encephalitis Virus Disease in the United States, 2003-2017. ( 30182919 )
2018
5
Evaluation of Argentinean Bird Species as Amplifying Hosts for St. Louis Encephalitis Virus (Flavivirus, Flaviviridae). ( 29761767 )
2018
6
Scented Sugar Baits Enhance Detection of St. Louis Encephalitis and West Nile Viruses in Mosquitoes in Suburban California. ( 29718284 )
2018
7
West Nile and St. Louis encephalitis viral genetic determinants of avian host competence. ( 29447156 )
2018
8
St. Louis encephalitis virus possibly transmitted through blood transfusion-Arizona, 2015. ( 28905395 )
2017
9
Diagnosis of Fatal Human Case of St. Louis Encephalitis Virus Infection by Metagenomic Sequencing, California, 2016. ( 28930022 )
2017
10
Neuroinvasive St. Louis Encephalitis Virus Infection in Solid Organ Transplant Recipients. ( 28452107 )
2017
11
Mutagen resistance and mutation restriction of St. Louis encephalitis virus. ( 28284278 )
2017
12
Toxicity of ar-curcumene and epi-β-bisabolol from Hedychium larsenii (Zingiberaceae) essential oil on malaria, chikungunya and St. Louis encephalitis mosquito vectors. ( 27918946 )
2017
13
Widespread Detection of Antibodies to Eastern Equine Encephalitis, West Nile, St. Louis Encephalitis, and Turlock Viruses in Various Species of Wild Birds from Across the United States. ( 27162269 )
2016
14
Reemergence of St. Louis Encephalitis Virus, California, 2015. ( 27869600 )
2016
15
Activity Patterns of St. Louis Encephalitis and West Nile Viruses in Free Ranging Birds during a Human Encephalitis Outbreak in Argentina. ( 27564679 )
2016
16
Astrocyte response to St. Louis encephalitis virus. ( 26975980 )
2016
17
Surveillance for Western Equine Encephalitis, St. Louis Encephalitis, and West Nile Viruses Using Reverse Transcription Loop-Mediated Isothermal Amplification. ( 26807734 )
2016
18
Concurrent Outbreaks of St. Louis Encephalitis Virus and West Nile Virus Disease - Arizona, 2015. ( 26656306 )
2015
19
Exploring Genomic, Geographic and Virulence Interactions among Epidemic and Non-Epidemic St. Louis Encephalitis Virus (Flavivirus) Strains. ( 26312485 )
2015
20
Multiplex qRT-PCR for the Detection of Western Equine Encephalomyelitis, St. Louis Encephalitis, and West Nile Viral RNA in Mosquito Pools (Diptera: Culicidae). ( 26334826 )
2015
21
St. Louis Encephalitis virus mosquito vectors dynamics in three different environments in relation to remotely sensed environmental conditions. ( 25792419 )
2015
22
First genome sequence of St. Louis encephalitis virus (SLEV) isolated from a human in Brazil. ( 25740285 )
2015
23
Genetic determinants of differential oral infection phenotypes of West Nile and St. Louis encephalitis viruses in Culex spp. mosquitoes. ( 25157120 )
2014
24
West Nile and st. Louis encephalitis viruses antibodies surveillance in captive and free-ranging birds of prey from Argentina. ( 25106849 )
2014
25
West Nile and St. Louis encephalitis viruses. ( 25015498 )
2014
26
St. Louis encephalitis virus infection in woman, Peru. ( 24655897 )
2014
27
Consequences of in vitro host shift for St. Louis encephalitis virus. ( 24643879 )
2014
28
Seroprevalence of St. Louis encephalitis virus and West Nile virus (Flavivirus, Flaviviridae) in horses, Uruguay. ( 24490165 )
2013
29
Provenance and geographic spread of St. Louis encephalitis virus. ( 23760463 )
2013
30
Transmission of endemic St Louis encephalitis virus strains by local Culex quinquefasciatus populations in Cordoba, Argentina. ( 23474474 )
2013
31
Structure of the St. Louis encephalitis virus postfusion envelope trimer. ( 23115296 )
2013
32
Effects of virus dose and extrinsic incubation temperature on vector competence of Culex nigripalpus (Diptera: Culicidae) for St. Louis encephalitis virus. ( 23270182 )
2012
33
Serological detection of St. Louis encephalitis virus and West Nile virus in equines from Santa Fe, Argentina. ( 22666870 )
2012
34
Molecular evidence of St. Louis encephalitis virus infection in patients in Buenos Aires, Argentina. ( 22608840 )
2012
35
Silent circulation of St. Louis encephalitis virus prior to an encephalitis outbreak in Cordoba, Argentina (2005). ( 22303490 )
2012
36
Structural gene (prME) chimeras of St Louis encephalitis virus and West Nile virus exhibit altered in vitro cytopathic and growth phenotypes. ( 21940408 )
2012
37
Seroconversion for West Nile and St. Louis encephalitis viruses among sentinel horses in Colombia. ( 22241119 )
2011
38
Immunoglobulin G subclasses in antibody responses to St. Louis encephalitis virus infections. ( 21688106 )
2011
39
Temporal and spatial alterations in mutant swarm size of St. Louis encephalitis virus in mosquito hosts. ( 21215334 )
2011
40
Evaluation of widely used diagnostic tests to detect West Nile virus infections in horses previously infected with St. Louis encephalitis virus or dengue virus type 2. ( 21346058 )
2011
41
Mosquito fauna inhabiting water bodies in the urban environment of Córdoba city, Argentina, following a St. Louis encephalitis outbreak. ( 21175948 )
2010
42
Vertical transmission of St. Louis encephalitis virus in Culex quinquefasciatus (Diptera: Culicidae) in Córdoba, Argentina. ( 20426683 )
2010
43
High throughput quantitative colorimetric microneutralization assay for the confirmation and differentiation of West Nile Virus and St. Louis encephalitis virus. ( 20207881 )
2010
44
Evolution and dispersal of St. Louis encephalitis virus in the Americas. ( 18708161 )
2009
45
Severe winter freezes enhance St. Louis encephalitis virus amplification and epidemic transmission in peninsular Florida. ( 19960704 )
2009
46
Experimental passage of St. Louis encephalitis virus in vivo in mosquitoes and chickens reveals evolutionarily significant virus characteristics. ( 19924238 )
2009
47
Effect of sequential exposure on infection and dissemination rates for West Nile and St. Louis encephalitis viruses in Culex quinquefasciatus. ( 19492941 )
2009
48
Comparative thermostability of West Nile, St. Louis encephalitis, and western equine encephalomyelitis viruses during heat inactivation for serologic diagnostics. ( 19407138 )
2009
49
Isolation of genotype V St. Louis encephalitis virus in Florida. ( 19331744 )
2009
50
A duplex real-time reverse transcriptase polymerase chain reaction assay for the detection of St. Louis encephalitis and eastern equine encephalitis viruses. ( 18715737 )
2008

Variations for St. Louis Encephalitis

Expression for St. Louis Encephalitis

Search GEO for disease gene expression data for St. Louis Encephalitis.

Pathways for St. Louis Encephalitis

Pathways related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.26 IFNA2 IFNA8

GO Terms for St. Louis Encephalitis

Cellular components related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 IFNA2 IFNA8 POMC RNASE1 RNASE3

Biological processes related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.69 IFNA2 IFNA8 POMC
2 cytokine-mediated signaling pathway GO:0019221 9.61 IFNA2 IFNA8 POMC
3 B cell differentiation GO:0030183 9.49 IFNA2 IFNA8
4 type I interferon signaling pathway GO:0060337 9.48 IFNA2 IFNA8
5 humoral immune response GO:0006959 9.46 IFNA2 IFNA8
6 defense response to virus GO:0051607 9.43 IFNA2 IFNA8 RNASE1
7 RNA phosphodiester bond hydrolysis GO:0090501 9.4 RNASE1 RNASE3
8 B cell proliferation GO:0042100 9.37 IFNA2 IFNA8
9 response to exogenous dsRNA GO:0043330 9.32 IFNA2 IFNA8
10 T cell activation involved in immune response GO:0002286 9.16 IFNA2 IFNA8
11 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 8.96 IFNA2 IFNA8
12 natural killer cell activation involved in immune response GO:0002323 8.62 IFNA2 IFNA8

Molecular functions related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endonuclease activity GO:0004519 9.26 RNASE1 RNASE3
2 ribonuclease activity GO:0004540 9.16 RNASE1 RNASE3
3 cytokine receptor binding GO:0005126 8.96 IFNA2 IFNA8
4 type I interferon receptor binding GO:0005132 8.62 IFNA2 IFNA8

Sources for St. Louis Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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