MCID: STL001
MIFTS: 38

St. Louis Encephalitis

Categories: Infectious diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for St. Louis Encephalitis

MalaCards integrated aliases for St. Louis Encephalitis:

Name: St. Louis Encephalitis 12 58 15 17
Encephalitis, St. Louis 44 70
Neuroinvasive St. Louis Encephalitis Virus Infection 12
Saint Louis Encephalitis 58

Characteristics:

Orphanet epidemiological data:

58
st. louis encephalitis
Inheritance: Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare neurological diseases
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:10845
ICD9CM 34 062.3
MeSH 44 D004674
SNOMED-CT 67 10429004
ICD10 32 A83.3
MESH via Orphanet 45 D004674
ICD10 via Orphanet 33 A83.3
UMLS via Orphanet 71 C0014060
Orphanet 58 ORPHA83484
UMLS 70 C0014060

Summaries for St. Louis Encephalitis

Disease Ontology : 12 A viral infectious disease that results in inflammation located in brain, has material basis in St. Louis encephalitis virus, which is transmitted by Culex mosquitoes. The infection has symptom headache, has symptom high fever, has symptom neck stiffness, has symptom stupor, has symptom disorientation, has symptom coma, has symptom tremors, has symptom convulsions and has symptom spastic paralysis.

MalaCards based summary : St. Louis Encephalitis, also known as encephalitis, st. louis, is related to eastern equine encephalitis and dengue disease, and has symptoms including headache, coma and tremors. An important gene associated with St. Louis Encephalitis is PRNT (Prion Locus LncRNA, Testis Expressed), and among its related pathways/superpathways are Interferon Pathway and all-trans-Retinoic Acid Mediated Apoptosis. Affiliated tissues include brain, salivary gland and kidney.

Wikipedia : 73 Saint Louis encephalitis is a disease caused by the mosquito-borne Saint Louis encephalitis virus. Saint... more...

Related Diseases for St. Louis Encephalitis

Diseases related to St. Louis Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 eastern equine encephalitis 30.5 IFNA1 ERVW-1
2 dengue disease 29.7 IFNA1 ERVW-1
3 encephalitis 11.4
4 west nile virus 10.9
5 western equine encephalitis 10.8
6 japanese encephalitis 10.7
7 dengue virus 10.5
8 yellow fever 10.5
9 meningoencephalitis 10.4
10 poliomyelitis 10.4
11 murray valley encephalitis 10.4
12 aseptic meningitis 10.4
13 shipyard eye 10.4
14 keratoconjunctivitis 10.4
15 triiodothyronine receptor auxiliary protein 10.3
16 la crosse encephalitis 10.2
17 tick-borne encephalitis 10.2
18 louping ill 10.2
19 rabies 10.2
20 vascular disease 10.2
21 viral infectious disease 10.2
22 venezuelan equine encephalitis 10.2
23 stomatitis 10.2
24 leukemia, chronic lymphocytic 10.1
25 ataxia and polyneuropathy, adult-onset 10.1
26 west nile encephalitis 10.1
27 neuroblastoma 10.1
28 viral hemorrhagic fever 10.1
29 meningitis and encephalitis 10.1
30 ocular motor apraxia 10.1
31 malaria 10.1
32 ifap syndrome 2 10.1
33 chikungunya 10.1
34 exanthem 10.1
35 mumps 10.1
36 hydrocephalus 10.1
37 sarcoma 10.1
38 cauda equina syndrome 10.1
39 allergic disease 10.1
40 status epilepticus 10.1
41 vaccinia 10.1
42 central nervous system disease 10.1
43 spindle cell sarcoma 10.1
44 polyradiculopathy 10.1
45 viral encephalitis 10.1
46 cerebrovascular disease 10.1
47 subacute thyroiditis 10.1
48 thyroiditis 10.1
49 cataract 10.1
50 measles 10.1

Graphical network of the top 20 diseases related to St. Louis Encephalitis:



Diseases related to St. Louis Encephalitis

Symptoms & Phenotypes for St. Louis Encephalitis

Symptoms:

12
  • headache
  • coma
  • tremors
  • disorientation
  • convulsions
  • neck stiffness
  • high fever
  • stupor
  • spastic paralysis

Drugs & Therapeutics for St. Louis Encephalitis

Search Clinical Trials , NIH Clinical Center for St. Louis Encephalitis

Cochrane evidence based reviews: encephalitis, st. louis

Genetic Tests for St. Louis Encephalitis

Anatomical Context for St. Louis Encephalitis

The Foundational Model of Anatomy Ontology organs/tissues related to St. Louis Encephalitis:

19
Brain

MalaCards organs/tissues related to St. Louis Encephalitis:

40
Brain, Salivary Gland, Kidney, Thymus, Pituitary

Publications for St. Louis Encephalitis

Articles related to St. Louis Encephalitis:

(show top 50) (show all 829)
# Title Authors PMID Year
1
Type I interferons are essential while type II interferon is dispensable for protection against St. Louis encephalitis virus infection in the mouse brain. 61
33410731 2021
2
Pathogenesis and shedding of Usutu virus in juvenile chickens. 61
33769213 2021
3
The abundance of Culex mosquito vectors for West Nile Virus and other flaviviruses: A time-series analysis of rainfall and temperature dependence in Singapore. 61
33254953 2021
4
A Review of the Control of Aedes aegypti (Diptera: Culicidae) in the Continental United States. 61
32829398 2021
5
Gonoactivity of Culex (Culex) (Diptera: Culicidae) Mosquitoes During Winter in Temperate Argentina. 61
33479774 2021
6
Serologic Survey of Mosquito-Borne Viruses in Hunter-Harvested White-Tailed Deer (Odocoileus virginianus), New York State. 61
33350367 2020
7
Diagnostic Approach for Arboviral Infections in the United States. 61
32938736 2020
8
Serological Evidence of West Nile Virus Infection in White-Tailed Deer in Central Texas. 61
32746746 2020
9
Autochthonous circulation of Saint Louis encephalitis and West Nile viruses in the Province of La Rioja, Argentina. 61
33176955 2020
10
Culex interfor and Culex saltanensis (Diptera: Culicidae) are susceptible and competent to transmit St. Louis encephalitis virus (Flavivirus: Flaviviridae) in central Argentina. 61
32722771 2020
11
Erratum to: Culex interfor and Culex saltanensis (Diptera: Culicidae) are susceptible and competent to transmit St. Louis encephalitis virus (Flavivirus: Flaviviridae) in central Argentina. 61
32844201 2020
12
Transmission of West Nile and five other temperate mosquito-borne viruses peaks at temperatures between 23°C and 26°C. 61
32930091 2020
13
Comparison of Characteristics of Patients with West Nile Virus or St. Louis Encephalitis Virus Neuroinvasive Disease During Concurrent Outbreaks, Maricopa County, Arizona, 2015. 61
32251616 2020
14
Assessment of Immunoglobulin M Enzyme-Linked Immunosorbent Assay Ratios to Identify West Nile Virus and St. Louis Encephalitis Virus Infections During Concurrent Outbreaks of West Nile Virus and St. Louis Encephalitis Virus Diseases, Arizona 2015. 61
32315576 2020
15
Interactions between the imperiled West Indian manatee, Trichechus manatus, and mosquitoes (Diptera: Culicidae) in Everglades National Park, Florida, USA. 61
32737372 2020
16
Identification and characterization of long noncoding RNAs and their association with acquisition of blood meal in Culex quinquefasciatus. 61
32621332 2020
17
Human Gene Sequences in SARS-CoV-2 and Other Viruses. 61
32503822 2020
18
Movement of St. Louis encephalitis virus in the Western United States, 2014- 2018. 61
32520944 2020
19
Mosquito Iridescent Virus: New Records from Nature and Infections Using Strelkovimermis spiculatus (Mermithidae) as a Vector Under Laboratory Conditions. 61
31903519 2020
20
Specific diagnostic method for St. Louis encephalitis virus using a non-structural protein as the antigen. 61
31846411 2020
21
Surveillance of a kdr Resistance Mutation in Culex pipiens (Diptera: Culicidae) and Culex quinquefasciatus in California. 61
31742344 2020
22
West Nile Virus and Other Domestic Nationally Notifiable Arboviral Diseases - United States, 2018. 61
31393865 2019
23
Description and phylogeny of the mitochondrial genome of Sabethes chloropterus, Sabethes glaucodaemon and Sabethes belisarioi (Diptera: Culicidae). 61
29581026 2019
24
Vector Competence for West Nile Virus and St. Louis Encephalitis Virus (Flavivirus) of Three Tick Species of the Genus Amblyomma (Acari: Ixodidae). 61
30887949 2019
25
Bloodmeal Host Selection of Culex quinquefasciatus (Diptera: Culicidae) in Las Vegas, Nevada, United States. 61
30668743 2019
26
Evaluation of a new West Nile virus nucleic acid test for screening of blood donations. 61
30427542 2019
27
Molecular characterization of viruses associated with encephalitis in São Paulo, Brazil. 61
30640927 2019
28
Serological evidence of arboviruses and coccidia infecting horses in the Amazonian region of Brazil. 61
31830142 2019
29
Larvicidal Activity of Synthesized Silver Nanoparticles from Curcuma zedoaria Essential Oil against Culex quinquefasciatus. 61
30641859 2019
30
Reemergence of St. Louis Encephalitis Virus in the Americas. 61
30457961 2018
31
Comparative studies of stenogamous behaviour in the mosquito Culex pipiens complex. 61
29856079 2018
32
First detection of Mansonia titillans (Diptera: Culicidae) infected with St. Louis encephalitis virus (Flaviviridae: Flavivirus) and Bunyamwera serogroup (Peribunyaviridae: Orthobunyavirus) in Argentina. 61
30408293 2018
33
St. Louis Encephalitis Virus Disease in the United States, 2003-2017. 61
30182919 2018
34
West Nile Virus and Other Nationally Notifiable Arboviral Diseases - United States, 2017. 61
30335737 2018
35
North American Culex pipiens and Culex quinquefasciatus are competent vectors for Usutu virus. 61
30118480 2018
36
Serological evidence of widespread exposure of Grenada fruit bats to chikungunya virus. 61
29575672 2018
37
Scented Sugar Baits Enhance Detection of St. Louis Encephalitis and West Nile Viruses in Mosquitoes in Suburban California. 61
29718284 2018
38
DNA barcoding of five Japanese encephalitis mosquito vectors (Culex fuscocephala, Culex gelidus, Culex tritaeniorhynchus, Culex pseudovishnui and Culex vishnui). 61
29625090 2018
39
Evaluation of Argentinean Bird Species as Amplifying Hosts for St. Louis Encephalitis Virus (Flavivirus, Flaviviridae). 61
29761767 2018
40
Human and Equine Infection with Alphaviruses and Flaviviruses in Panamá during 2010: A Cross-Sectional Study of Household Contacts during an Encephalitis Outbreak. 61
29737271 2018
41
Mosquito control with green nanopesticides: towards the One Health approach? A review of non-target effects. 61
28755145 2018
42
False-Positive Monospot in a Returning Traveler with Dengue Fever. 61
29514339 2018
43
The jungle book of neuropsychology: Disentangling the influence of feral childhood from adult brain injury in order to provide effective rehabilitation. 61
29214905 2018
44
Heterogeneous distribution of Culex pipiens, Culex quinquefasciatus and their hybrids along the urbanisation gradient. 61
29198600 2018
45
Environmental stochasticity and intraspecific competition influence the population dynamics of Culex quinquefasciatus (Diptera: Culicidae). 61
29482608 2018
46
West Nile and St. Louis encephalitis viral genetic determinants of avian host competence. 61
29447156 2018
47
Sampling Design and Mosquito Trapping for Surveillance of Arboviral Activity. 61
28986827 2018
48
West Nile Virus and Other Nationally Notifiable Arboviral Diseases - United States, 2016. 61
29324725 2018
49
A Serological Protein Microarray for Detection of Multiple Cross-Reactive Flavivirus Infections in Horses for Veterinary and Public Health Surveillance. 61
27633257 2017
50
St. Louis encephalitis virus possibly transmitted through blood transfusion-Arizona, 2015. 61
28905395 2017

Variations for St. Louis Encephalitis

Expression for St. Louis Encephalitis

Search GEO for disease gene expression data for St. Louis Encephalitis.

Pathways for St. Louis Encephalitis

Pathways related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.91 IFNA8 IFNA1
2 10.3 IFNA8 IFNA1

GO Terms for St. Louis Encephalitis

Cellular components related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Schaffer collateral - CA1 synapse GO:0098685 9.26 NTNG2 NTNG1
2 anchored component of plasma membrane GO:0046658 9.16 NTNG2 NTNG1
3 laminin complex GO:0043256 8.96 NTNG2 NTNG1
4 anchored component of presynaptic active zone membrane GO:0099029 8.62 NTNG2 NTNG1

Biological processes related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 9.56 IFNA8 IFNA1
2 modulation of chemical synaptic transmission GO:0050804 9.55 NTNG2 NTNG1
3 type I interferon signaling pathway GO:0060337 9.54 IFNA8 IFNA1
4 humoral immune response GO:0006959 9.52 IFNA8 IFNA1
5 substrate adhesion-dependent cell spreading GO:0034446 9.51 NTNG2 NTNG1
6 regulation of neuron projection development GO:0010975 9.49 NTNG2 NTNG1
7 tissue development GO:0009888 9.48 NTNG2 NTNG1
8 response to exogenous dsRNA GO:0043330 9.46 IFNA8 IFNA1
9 B cell proliferation GO:0042100 9.43 IFNA8 IFNA1
10 T cell activation involved in immune response GO:0002286 9.4 IFNA8 IFNA1
11 synaptic membrane adhesion GO:0099560 9.37 NTNG2 NTNG1
12 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.32 IFNA8 IFNA1
13 natural killer cell activation involved in immune response GO:0002323 9.26 IFNA8 IFNA1
14 regulation of neuron migration GO:2001222 9.16 NTNG2 NTNG1
15 basement membrane assembly GO:0070831 8.96 NTNG2 NTNG1
16 regulation of neuron projection arborization GO:0150011 8.62 NTNG2 NTNG1

Molecular functions related to St. Louis Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor binding GO:0005126 8.96 IFNA8 IFNA1
2 type I interferon receptor binding GO:0005132 8.62 IFNA8 IFNA1

Sources for St. Louis Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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