MCID: STP007
MIFTS: 22

Staphylococcal Scarlet Fever

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Staphylococcal Scarlet Fever

MalaCards integrated aliases for Staphylococcal Scarlet Fever:

Name: Staphylococcal Scarlet Fever 59 55
Staphylococcal Toxic Shock Syndrome 72

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

ICD10 via Orphanet 34 A38
Orphanet 59 ORPHA36235
UMLS 72 C3714602

Summaries for Staphylococcal Scarlet Fever

MalaCards based summary : Staphylococcal Scarlet Fever, also known as staphylococcal toxic shock syndrome, is related to scarlet fever and exanthem. An important gene associated with Staphylococcal Scarlet Fever is EDNRA (Endothelin Receptor Type A). The drugs Clindamycin and Clavulanate have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and monocytes.

Related Diseases for Staphylococcal Scarlet Fever

Diseases related to Staphylococcal Scarlet Fever via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 scarlet fever 10.7
2 exanthem 10.3
3 toxic shock syndrome 10.3
4 allergic hypersensitivity disease 10.1
5 uveitis 10.1
6 otitis externa 10.1
7 anterior uveitis 10.1
8 staphylococcal toxic shock syndrome 10.1

Graphical network of the top 20 diseases related to Staphylococcal Scarlet Fever:



Diseases related to Staphylococcal Scarlet Fever

Symptoms & Phenotypes for Staphylococcal Scarlet Fever

Drugs & Therapeutics for Staphylococcal Scarlet Fever

Drugs for Staphylococcal Scarlet Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
2
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
3
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
4
Rifampicin Approved Phase 4 13292-46-1 5381226 5458213
5
Proline Approved, Nutraceutical Phase 4 147-85-3 145742
6
Imidacloprid Vet_approved Phase 4 105827-78-9 86418
7 Antibodies Phase 4
8 Anti-Bacterial Agents Phase 4
9 Pharmaceutical Solutions Phase 4
10 Anti-Infective Agents Phase 4
11 Clindamycin palmitate Phase 4
12 Amoxicillin-Potassium Clavulanate Combination Phase 4
13 Immunologic Factors Phase 4
14 gamma-Globulins Phase 4
15 Immunoglobulins Phase 4
16 Antibiotics, Antitubercular Phase 4
17 Clindamycin phosphate Phase 4
18 Immunoglobulins, Intravenous Phase 4
19 Rho(D) Immune Globulin Phase 4
20 beta-Lactamase Inhibitors Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Children: a Multicentre European Randomized Controlled Trial Not yet recruiting NCT02899702 Phase 4 PRIVIGEN (CSL Behring);Albumin

Search NIH Clinical Center for Staphylococcal Scarlet Fever

Genetic Tests for Staphylococcal Scarlet Fever

Anatomical Context for Staphylococcal Scarlet Fever

MalaCards organs/tissues related to Staphylococcal Scarlet Fever:

41
Skin, T Cells, Monocytes, Breast, B Cells, Testes, Bone

Publications for Staphylococcal Scarlet Fever

Articles related to Staphylococcal Scarlet Fever:

(show top 50) (show all 213)
# Title Authors PMID Year
1
Toxin involvement in staphylococcal scalded skin syndrome. 9 38
9431380 1997
2
An Elusive Case of Mycosis Fungoides: Case Report and Review of the Literature. 38
31388911 2019
3
Staphylococcal scarlet fever associated with staphylococcal enterotoxin M in an elderly patient. 38
31096050 2019
4
[Staphylococcal toxic shock syndrome should be considered in the event of diffuse erythema with fever and shock]. 38
30691878 2019
5
Molecular Typing and Variations in Amount of tst Gene Expression of TSST-1-Producing Clinical Staphylococcus aureus Isolates. 38
31275293 2019
6
[Intravenous immunoglobulin therapy in non-menstrual staphylococcal toxic shock syndrome]. 38
29050863 2018
7
Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom. 38
29350159 2018
8
Erratum: Intense, flu-like symptoms in women using menstrual devices: always think of staphylococcal Toxic Shock Syndrome. 38
28721224 2017
9
Intense, flu-like symptoms in women using menstrual devices: always think of staphylococcal Toxic Shock Syndrome. 38
28580155 2017
10
[Staphylococcal toxic shock syndrome at a chronic hemodialysis]. 38
28979632 2017
11
HLA-DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model. 38
27863161 2017
12
Fatal endocarditis with methicilin-sensible Staphylococcus aureus and major complications: rhabdomyolysis, pericarditis, and intracerebral hematoma: A case report and review of the literature. 38
27741135 2016
13
Acute encephalopathy with biphasic seizures and late reduced diffusion associated with staphylococcal toxic shock syndrome caused by burns. 38
27117386 2016
14
Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature. 38
29967859 2016
15
Safety, tolerability, and immunogenicity of a recombinant toxic shock syndrome toxin (rTSST)-1 variant vaccine: a randomised, double-blind, adjuvant-controlled, dose escalation first-in-man trial. 38
27296693 2016
16
Nosocomial Staphylococcal Toxic Shock. Case Report. 38
29967853 2016
17
Lactobacilli require physical contact to reduce staphylococcal TSST-1 secretion and vaginal epithelial inflammatory response. 38
27060097 2016
18
The Management of Staphylococcal Toxic Shock Syndrome. A Case Report. 38
29967843 2016
19
Staphylococcal Toxic Shock Syndrome Caused by an Intravaginal Product. A Case Report. 38
29967837 2016
20
Unusual staphylococcal toxic shock syndrome presenting as a scarlet-like fever. 38
26543563 2015
21
Staphylococcal Purpura Fulminans: Report of a Case. 38
25099358 2015
22
A fatal case of staphylococcal toxic shock syndrome. 38
26265799 2015
23
Evidence of staphylococcal toxic shock syndrome caused by MRSA in a mother-newborn pair. 38
25260039 2015
24
Neutralization of staphylococcal enterotoxin B by an aptamer antagonist. 38
25624325 2015
25
[Severe burns related to steam inhalation therapy]. 38
24768268 2015
26
Staphylococcal toxic shock syndrome caused by tampon use. 38
25692047 2015
27
[Staphylococcal toxic shock syndrome after breast surgery]. 38
24636869 2014
28
Staphylococcal toxic shock syndrome: superantigen-mediated enhancement of endotoxin shock and adaptive immune suppression. 38
24816557 2014
29
The impact of Staphylococcus aureus-associated molecular patterns on staphylococcal superantigen-induced toxic shock syndrome and pneumonia. 38
25024509 2014
30
Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome. 38
24423010 2014
31
Vaccination with plasmid DNA encoding a mutant toxic shock syndrome toxin-1 ameliorates toxin-induced lethal shock in mice. 38
23985881 2013
32
Images in clinical medicine. Staphylococcal toxic shock syndrome. 38
23984732 2013
33
Skin findings of Staphylococcus aureus toxin-mediated infection in relation to toxin encoding genes. 38
23446443 2013
34
Clinical features and etiology of adult patients with Fever and rash. 38
23197907 2012
35
Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. 38
22431984 2012
36
Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30. 38
22919639 2012
37
Scarlet fever caused by community-associated methicillin-resistant Staphylococcus aureus. 38
21813926 2011
38
[Staphylococcal toxic shock syndrome in a 5 year-old child]. 38
21470720 2011
39
Staphylococcal toxic shock syndrome 2000-2006: epidemiology, clinical features, and molecular characteristics. 38
21860665 2011
40
Toxigenic status of Staphylococcus aureus isolated from bovine raw milk and Minas frescal cheese in Brazil. 38
21219740 2010
41
Staphylococcal toxic shock syndrome: mechanisms and management. 38
21308522 2010
42
Toxic shock syndrome toxin-1 (TSST-1) antibody levels in Japanese children. 38
20036064 2010
43
Use of recombinant human activated protein C in nonmenstrual staphylococcal toxic shock syndrome. 38
21253349 2010
44
TLR2 signalling: At the crossroads of commensalism, invasive infections and toxic shock syndrome by Staphylococcus aureus. 38
20363358 2010
45
Staphylococcal toxic shock syndrome, superantigenicity, and hypersensitivity. 38
20367234 2010
46
Staphylococcus aureus exotoxins are present in vivo in tampons. 38
20335433 2010
47
Staphylococcal toxic shock syndrome presenting as acute respiratory distress and cor pulmonale. 38
20196940 2010
48
Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. 38
19911998 2009
49
Panton-Valentine leukocidin is associated with exacerbated skin manifestations and inflammatory response in children with community-associated staphylococcal scarlet fever. 38
19725782 2009
50
Evaluation of surveillance methods for staphylococcal toxic shock syndrome. 38
19402965 2009

Variations for Staphylococcal Scarlet Fever

Expression for Staphylococcal Scarlet Fever

Search GEO for disease gene expression data for Staphylococcal Scarlet Fever.

Pathways for Staphylococcal Scarlet Fever

GO Terms for Staphylococcal Scarlet Fever

Sources for Staphylococcal Scarlet Fever

3 CDC
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10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
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44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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