Startle Epilepsy disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Orphanet: ⁵⁸ Startle epilepsy is a rare neurologic disease characterized by frequent and spontaneous epileptic seizures (frequently with symmetrical or asymmetrical tonic features) triggered by a normal startle in response to a sudden and unexpected somatosensory (most frequently auditory) stimulus. Falls are common and can be traumatic. In most cases, the disease is associated with spastic hemi-, di-, or tetraplegia and intellectual disability.

MalaCards based summary: Startle Epilepsy is related to reflex epilepsy and audiogenic seizures. Affiliated tissues include cortex and brain.

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Related Diseases for Startle Epilepsy

Diseases related to Startle Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)

#	Related Disease	Score
1	reflex epilepsy	11.1
2	audiogenic seizures	11.1
3	epilepsy	10.5
4	visual epilepsy	10.3
5	hemiplegia	10.1
6	ehlers-danlos syndrome, arthrochalasia type, 1	10.0
7	down syndrome	10.0
8	hyperekplexia	10.0
9	cerebral palsy	10.0
10	encephalitis	10.0
11	herpes simplex encephalitis	10.0
12	myoclonus	10.0
13	neonatal hypoxic and ischemic brain injury	10.0
14	aspartylglucosaminuria	9.9
15	papillon-lefevre syndrome	9.9
16	polymicrogyria, bilateral perisylvian, x-linked	9.9
17	schuurs-hoeijmakers syndrome	9.9
18	lennox-gastaut syndrome	9.9
19	porencephaly	9.9
20	polymicrogyria	9.9
21	asphyxia neonatorum	9.9
22	status epilepticus	9.9
23	encephalomalacia	9.9
24	focal epilepsy	9.9
25	gastric antral vascular ectasia	9.9
26	hemangioma	9.9
27	early myoclonic encephalopathy	9.9
28	learning disability	9.9
29	bacterial meningitis	9.9
30	pacs1 neurodevelopmental disorder	9.9
31	encephalopathy	9.9
32	febrile seizures	9.9
33	nmda receptor encephalitis	9.9
34	myoclonic epilepsy of infancy	9.9

Graphical network of the top 20 diseases related to Startle Epilepsy:

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Symptoms & Phenotypes for Startle Epilepsy

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Drugs & Therapeutics for Startle Epilepsy

Search Clinical Trials, NIH Clinical Center for Startle Epilepsy

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Genetic Tests for Startle Epilepsy

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Anatomical Context for Startle Epilepsy

Organs/tissues related to Startle Epilepsy:

MalaCards : Cortex, Brain

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Publications for Startle Epilepsy

Articles related to Startle Epilepsy:

(show top 50) (show all 59)

#	Title	Authors	PMID	Year
1	Intractable startle epilepsy in Schuurs - Hoeijmakers syndrome. ⁶²	Ohta K...Maegaki Y	35770753	2022
2	Startle Epilepsy Triggered By Maternal Cough. ⁶²	Savage MC...Ebrahimi-Fakhari D	34192791	2021
3	Reflex Epilepsy. ⁶²	Hanif S...Musick ST	34221545	2021
4	Reduced chain length in myelin sphingolipids and poorer motor coordination in mice deficient in the fatty acid elongase Elovl1. ⁶²	Isokawa M...Kihara A	32123819	2019
5	Postherpetic Anti-N-methyl-D-aspartate Receptor Encephalitis after Hemispherotomy in a Patient with Intractable Startle Epilepsy. ⁶²	Erkent I...Saygi S	28938499	2018
6	Electroclinical and cytogenetic features of epilepsy in cri-du-chat syndrome. ⁶²	Nakagami Y...Inoue Y	26576006	2015
7	A case of startle epilepsy associated with IL1RAPL1 gene deletion. ⁶²	Dinopoulos A...Papaevangelou V	24950661	2014
8	The pivotal role of the supplementary motor area in startle epilepsy as demonstrated by SEEG epileptogenicity maps. ⁶²	Job AS...Kahane P	24902865	2014
9	Noninvasive treatment alternative for intractable startle epilepsy. ⁶²	Klinkenberg S...Brokx J	25667869	2014
10	Corpus callosotomy in a patient with startle epilepsy. ⁶²	Gomez NG...Centeno R	23531553	2013
11	Seizure-free after surgery in a patient with non-lesional startle epilepsy: a case report. ⁶²	Sun YP...Wang YP	23141145	2012
12	Surgical treatment in startle epilepsy. ⁶²	Tian H...Zhou W	22824695	2012
13	Hemispherectomy in pediatric patients with epilepsy: a study of 45 cases with special emphasis on epileptic syndromes. ⁶²	Caraballo R...Pomata H	21947090	2011
14	Adult onset startle epilepsy. ⁶²	Moseley BD...Shin C	22675038	2011
15	Functional neuroimaging in startle epilepsy: involvement of a mesial frontoparietal network. ⁶²	Fernandez S...Carreno M	21770921	2011
16	Startle syndromes. ⁶²	Bhidayasiri R...Truong DD	21496599	2011
17	Clinical and electrophysiological characteristics of startle epilepsy in childhood. ⁶²	Yang Z...Chang X	20071222	2010
18	A hemispherotomy for intractable startle epilepsy characterized by infantile hemiplegia and drop attacks. ⁶²	Anan M...Baba H	19766495	2009
19	A clinical and magnetoencephalography study of MRI-negative startle epilepsy. ⁶²	Garcia-Morales I...Gil-Nagel A	19635686	2009
20	Startle epilepsy associated with gait-induced seizures: Pathomechanism analysis using EEG, MEG, and PET studies. ⁶²	Saeki K...Kaneko Y	19400869	2009
21	Startle epilepsy associated with infantile hemiplegia (SEIH): video-polygraphic features and long-term outcome. ⁶²	d'Orsi G...Coppola G	19809941	2009
22	The efficacy and tolerability of Levetiracetam as an add-on therapy in patients with startle epilepsy. ⁶²	Gurses C...Gokyigit A	18486495	2008
23	Startle and its disorders. ⁶²	Meinck HM	17336782	2006
24	Proven startle-provoked epileptic seizures in childhood: semiologic and electrophysiologic variability. ⁶²	Tibussek D...Schmitt B	16822252	2006
25	The movement disorders of Coffin-Lowry syndrome. ⁶²	Stephenson JB...Zuberi SM	15668049	2005
26	Intractable reflex audiogenic epilepsy successfully treated by peri-insular hemispherotomy. ⁶²	Martinez-Manas R...Deonna T	15324827	2004
27	Startle epilepsy complicating aspartylglucosaminuria. ⁶²	Labate A...Quattrone A	15036433	2004
28	[Hemiparetic cerebral palsy and startle epilepsy]. ⁶²	Caraballo R...Fejerman N	14752709	2004
29	Reflex myoclonic epilepsy in infancy: a benign age-dependent idiopathic startle epilepsy. ⁶²	Zafeiriou D...Kontopoulos E	12875957	2003
30	[The association between post anoxic encephalopathy and startle epilepsy]. ⁶²	Pardal-aern ndez JM...Lopez-Agreda JM	12080514	2002
31	Startle response: epileptic or non-epileptic? The case for "flash" SMA reflex seizures. ⁶²	Cokar O...Genton P	11313216	2001
32	Postoperative seizure outcome after corpus callosotomy in reflex epilepsy. ⁶²	Kwan SY...Su MS	10746422	2000
33	A case of startle epilepsy and SSMA seizures documented with subdural recordings. ⁶²	Serles W...Baumgartner C	10403230	1999
34	Epidemiology of epilepsy in childhood: a cohort of 440 consecutive patients. ⁶²	Kramer U...Harel S	9492091	1998
35	Startle epilepsy with infantile hemiplegia: report of two cases improved by surgery. ⁶²	Oguni H...Shimizu H	9578019	1998
36	Reflex partial seizures of sensorimotor cortex (including cortical reflex myoclonus and startle epilepsy). ⁶²	Vignal JP...Reutens DC	9385423	1998
37	Vomiting attack with ACTH and ADH discharge improves startle epilepsy. ⁶²	Hayashi M...Maruki K	8805177	1996
38	Startle epilepsy presenting as drop attacks: a case report. ⁶²	Lin YY...Chang KP	8548670	1995
39	From the jumping Frenchmen of Maine to post-traumatic stress disorder: the startle response in neuropsychiatry. ⁶²	Howard R...Ford R	1410093	1992
40	Startle epilepsy--a case report. ⁶²	Agrawal P...Malik SC	1743747	1991
41	[The startle response and epilepsy]. ⁶²	Graf M...Wimmer G	2111612	1990
42	Startle disorders of man: hyperekplexia, jumping and startle epilepsy. ⁶²	Andermann F...Andermann E	3064625	1988
43	Excessive startle syndromes: startle disease, jumping, and startle epilepsy. ⁶²	Andermann F...Andermann E	3511629	1986
44	Sustained myoclonus in a woman with startle epilepsy. ⁶²	Bejar JM...Ziegler DK	4037744	1985
45	[Startle epilepsy: review of the literature and case report]. ⁶²	Conde Lopez V...Franco Martin MA	4025029	1985
46	Startle-induced epileptic seizures. ⁶²	Aguglia U...Gastaut H	6510379	1984
47	Startle epilepsy: a clinical study. ⁶²	Saenz-Lope E...Masdeu JC	6465864	1984
48	Hyperekplexia: a syndrome of pathological startle responses. ⁶²	Saenz-Lope E...Chacon Pena JR	6424556	1984
49	The "startle disease" in brain-damaged patients: report of a case. ⁶²	Baier WK	6894024	1980
50	Startle epilepsy complicating Down syndrome during adulthood. ⁶²	Gimenez-Roldan S...Martin M	6444792	1980

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Genes for Startle Epilepsy

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Variations for Startle Epilepsy

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Expression for Startle Epilepsy

Search GEO for disease gene expression data for Startle Epilepsy.

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Pathways for Startle Epilepsy

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GO Terms for Startle Epilepsy

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Sources for Startle Epilepsy

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MCID: STR070 MIFTS: 14	Startle Epilepsy Categories: Neuronal diseases, Rare diseases	Data Licensing For inquiries, contact: [email protected]
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