MCID: STT044
MIFTS: 11

Statin Toxicity

Categories: Rare diseases

Aliases & Classifications for Statin Toxicity

MalaCards integrated aliases for Statin Toxicity:

Name: Statin Toxicity 59

Classifications:



External Ids:

Orphanet 59 ORPHA413696

Summaries for Statin Toxicity

MalaCards based summary : Statin Toxicity is related to hepatitis and viral hepatitis. The drugs Atorvastatin Calcium and Hydroxymethylglutaryl-CoA Reductase Inhibitors have been mentioned in the context of this disorder.

Related Diseases for Statin Toxicity

Diseases related to Statin Toxicity via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hepatitis 9.6
2 viral hepatitis 9.6

Symptoms & Phenotypes for Statin Toxicity

Drugs & Therapeutics for Statin Toxicity

Drugs for Statin Toxicity (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Atorvastatin Calcium Phase 4 134523-03-8
2 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
3 Hypolipidemic Agents Phase 4
4 Anticholesteremic Agents Phase 4
5 Lipid Regulating Agents Phase 4
6 Antimetabolites Phase 4
7 Calcium, Dietary Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Association Between Systemic Exposure of Atorvastatin and Metabolites and Atorvastatin-induced Myotoxicity Completed NCT00120055 Phase 4 Atorvastatin (Lipitor)

Search NIH Clinical Center for Statin Toxicity

Genetic Tests for Statin Toxicity

Anatomical Context for Statin Toxicity

Publications for Statin Toxicity

Articles related to Statin Toxicity:

# Title Authors Year
1
Efficiency of hepatocyte pretreatment with coenzyme Q10 against statin toxicity. ( 24535294 )
2014
2
Statin toxicity from macrolide antibiotic coprescription. ( 24126654 )
2013
3
Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. ( 23778904 )
2013
4
Statin toxicity from macrolide antibiotic coprescription. ( 24126655 )
2013
5
Transporter pharmacogenetics and statin toxicity. ( 19890253 )
2010
6
Statin toxicity: a situation that mimics viral hepatitis. ( 16300170 )
2005
7
Reversal of statin toxicity to human lymphocytes in tissue culture. ( 14682607 )
2003

Variations for Statin Toxicity

Expression for Statin Toxicity

Search GEO for disease gene expression data for Statin Toxicity.

Pathways for Statin Toxicity

GO Terms for Statin Toxicity

Sources for Statin Toxicity

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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