MCID: STR017
MIFTS: 25

Sternum Cancer

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Sternum Cancer

MalaCards integrated aliases for Sternum Cancer:

Name: Sternum Cancer 12 15
Malignant Sternal Neoplasm 12 73
Neoplasm of Sternum 12 73
Malignant Sternal Tumor 12
Sternal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5090
NCIt 50 C6730 C8408
SNOMED-CT 68 126559003

Summaries for Sternum Cancer

Disease Ontology : 12 A bone cancer and neoplasm of chest wall and sternal disorder that is located in the sternum.

MalaCards based summary : Sternum Cancer, also known as malignant sternal neoplasm, is related to extragonadal nonseminomatous germ cell tumor and corpus luteum cyst. An important gene associated with Sternum Cancer is VIM (Vimentin), and among its related pathways/superpathways is B Cell Development Pathways. Affiliated tissues include the sternum and bone.

Related Diseases for Sternum Cancer

Diseases related to Sternum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 extragonadal nonseminomatous germ cell tumor 10.5 AFP SMUG1
2 corpus luteum cyst 10.5 AFP SMUG1
3 extragonadal germ cell cancer 10.5 AFP SMUG1
4 glomangiomyoma 10.5 CD34 VIM
5 oculomotor nerve paralysis 10.4 AFP SMUG1
6 adenomatoid tumor 10.4 AFP VIM
7 third cranial nerve disease 10.4 AFP SMUG1
8 endometrial small cell carcinoma 10.4 AFP SMUG1
9 tibial adamantinoma 10.4 CD34 SMUG1
10 nodular hidradenoma 10.4 FUT4 VIM
11 mediastinal cancer 10.4 AFP SMUG1
12 spleen angiosarcoma 10.4 CD34 SMUG1
13 breast leiomyosarcoma 10.4 CD34 SMUG1
14 bone epithelioid hemangioma 10.4 CD34 SMUG1
15 mature teratoma 10.4 AFP SMUG1
16 extraosseous osteosarcoma 10.4 CD34 SMUG1
17 endodermal sinus tumor 10.4 AFP VIM
18 senile angioma 10.4 CD34 VIM
19 malignant pineal area germ cell neoplasm 10.4 AFP CD34
20 eccrine adenocarcinoma 10.4 CD34 SMUG1
21 hemidystonia 10.4 SMUG1 VIM
22 liver inflammatory pseudotumor 10.3 AFP CD34
23 pericardial mesothelioma 10.3 SMUG1 VIM
24 lymphangiosarcoma 10.3 CD34 SMUG1
25 liver angiosarcoma 10.2 CD34 VIM
26 malignant biphasic mesothelioma 10.2 AFP FUT4
27 reticulum cell sarcoma 10.2 TNFRSF8 VIM
28 mixed germ cell cancer 10.2 AFP FUT4
29 ovarian embryonal carcinoma 10.2 AFP TNFRSF8
30 secretory meningioma 10.2 FUT4 VIM
31 adult lymphoma 10.2 SMUG1 TNFRSF8
32 intratubular embryonal carcinoma 10.2 AFP TNFRSF8
33 paraphimosis 10.1 CD34 TNFRSF8
34 glomangioma 10.1 CD34 VIM
35 extragonadal seminoma 10.1 AFP TNFRSF8
36 peliosis hepatis 10.1 AFP SMUG1 VIM
37 pulmonary artery leiomyosarcoma 10.1 CD68 SMUG1
38 germ cell and embryonal cancer 10.0 AFP FUT4
39 epidural neoplasm 10.0 FUT4 TNFRSF8
40 brain sarcoma 10.0 CD68 SMUG1
41 dermatofibrosarcoma protuberans 10.0 CD34 VIM
42 lung lymphoma 10.0 SMUG1 TNFRSF8
43 lactocele 10.0 CD68 SMUG1
44 granular cell tumor 10.0 CD68 VIM
45 mediastinal malignant lymphoma 10.0 FUT4 TNFRSF8
46 liposarcoma 10.0 CD34 VIM
47 dendritic cell tumor 9.9 CD68 VIM
48 liver sarcoma 9.9 AFP CD68
49 retina lymphoma 9.9 CD34 CD68
50 extracutaneous mastocytoma 9.9 CD34 CD68

Graphical network of the top 20 diseases related to Sternum Cancer:



Diseases related to Sternum Cancer

Symptoms & Phenotypes for Sternum Cancer

Drugs & Therapeutics for Sternum Cancer

Search Clinical Trials , NIH Clinical Center for Sternum Cancer

Genetic Tests for Sternum Cancer

Anatomical Context for Sternum Cancer

The Foundational Model of Anatomy Ontology organs/tissues related to Sternum Cancer:

19
The Sternum

MalaCards organs/tissues related to Sternum Cancer:

41
Bone

Publications for Sternum Cancer

Articles related to Sternum Cancer:

# Title Authors Year
1
Plasmacytoma--a rare sternal tumor. ( 24368859 )
2014
2
[Sternal tumor and its surgical excision and reconstruction]. ( 4474237 )
1974

Variations for Sternum Cancer

Expression for Sternum Cancer

Search GEO for disease gene expression data for Sternum Cancer.

Pathways for Sternum Cancer

Pathways related to Sternum Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.35 CD34 TNFRSF8

GO Terms for Sternum Cancer

Cellular components related to Sternum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 FUT4

Biological processes related to Sternum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron projection development GO:0010977 8.96 TNFRSF8 VIM
2 SMAD protein signal transduction GO:0060395 8.62 AFP VIM

Sources for Sternum Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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