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MCID: STM007
MIFTS: 49

Stomatitis

Categories: Oral diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Stomatitis

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MalaCards integrated aliases for Stomatitis:

Name: Stomatitis 12 74 54 43 15 17 71

Classifications:

MalaCards categories:
Anatomical: Oral diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:9637
MeSH 43 D013280
NCIt 49 C26887
SNOMED-CT 67 61170000 95361005
ICD10 32 K12.1
UMLS 71 C0038362
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Summaries for Stomatitis

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MalaCards based summary : Stomatitis is related to chikungunya and hepatitis c virus, and has symptoms including enanthema, oral mucosal blisters and oral manifestations. An important gene associated with Stomatitis is LDLR (Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Morphine and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include breast, t cells and lung, and related phenotype is immune system.

Wikipedia : 74 Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

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Related Diseases for Stomatitis

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Diseases related to Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 514)
# Related Disease Score Top Affiliating Genes
1 chikungunya 30.5 RSAD2 DDX58 BST2
2 hepatitis c virus 30.4 RSAD2 LDLR EIF2AK2 DDX58 BST2 ATG5
3 influenza 30.3 RSAD2 NUP98 IFITM3 IFITM2 EIF2AK2 DDX58
4 west nile virus 30.3 RSAD2 IFITM3 IFITM2 DDX58
5 dengue virus 30.2 RSAD2 IFITM3 IFITM2 DDX58
6 hepatitis c 30.1 RSAD2 LDLR IFNA2 EIF2AK2 DDX58
7 mucositis 30.1 FGF7 CSF3 CSF2
8 rift valley fever 30.1 IFITM3 IFITM2 EIF2AK2
9 granulocytopenia 29.9 CSF3 CSF2
10 common cold 29.8 LDLR IFNA2 CSF2
11 skin disease 29.6 TP63 FGF7 DDX58 CSF2 ADAR
12 chronic myelomonocytic leukemia 29.1 NUP98 CSF3 CSF2
13 aphthous stomatitis 12.7
14 denture stomatitis 12.6
15 ulcerative stomatitis 12.6
16 sutton disease 2 12.2
17 noma 11.8
18 hand, foot and mouth disease 11.7
19 ariboflavinosis 11.5
20 glucagonoma 11.5
21 angular cheilitis 11.5
22 necrotizing ulcerative gingivitis 11.5
23 marshall syndrome 11.4
24 methylmalonic aciduria and homocystinuria, cblf type 11.2
25 oral candidiasis 10.9
26 pharyngitis 10.8
27 cervical adenitis 10.6
28 vaccinia 10.5
29 herpes simplex 10.5
30 mouth disease 10.5
31 gingivitis 10.5
32 rabies 10.5
33 lichen planus 10.5
34 helix syndrome 10.5
35 candidiasis 10.4
36 glossitis 10.4
37 human immunodeficiency virus type 1 10.4
38 pinguecula 10.4 TP63 LDLR
39 newcastle disease 10.4
40 dermatitis 10.4
41 measles 10.4
42 oral lichen planus 10.4
43 aicardi-goutieres syndrome 10.3 RSAD2 DDX58 BST2 ADAR
44 microphthalmia with limb anomalies 10.3 RSAD2 EIF2AK2 DDX58 BST2
45 encephalitis 10.3
46 exanthem 10.3
47 neutropenia 10.3
48 cheilitis 10.3
49 periodontitis 10.3
50 human t-cell leukemia virus type 2 10.3 CSF2 ADAR

Graphical network of the top 20 diseases related to Stomatitis:



Diseases related to Stomatitis
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Symptoms & Phenotypes for Stomatitis

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UMLS symptoms related to Stomatitis:


enanthema, oral mucosal blisters, oral manifestations, burning mucosal, oral pain, sore roof of mouth (symptom)

MGI Mouse Phenotypes related to Stomatitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.4 ADAR ATG5 CSF2 CSF3 DDX58 EIF2AK2
Sources

Drugs & Therapeutics for Stomatitis

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Drugs for Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 383)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Morphine Approved, Investigational Phase 4 57-27-2 5288826
2
Ethanol Approved Phase 4 64-17-5 702
3
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
4
Racepinephrine Approved Phase 4 329-65-7 838
5
Hexetidine Approved, Investigational Phase 4 141-94-6
6
Sodium citrate Approved, Investigational Phase 4 68-04-2
7
Pemetrexed Approved, Investigational Phase 4 150399-23-8, 137281-23-3 446556 60843
8
Cefpirome Approved Phase 4 84957-29-9 5479539
9
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
10
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
11
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
12
Polyestradiol phosphate Approved Phase 4 28014-46-2
13
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
14
Hydroxocobalamin Approved Phase 4 13422-51-0 11953898 15589840
15
leucovorin Approved Phase 4 58-05-9 6006 143
16
Silicon Approved, Investigational Phase 4 7440-21-3 4082203
17
Amifostine Approved, Investigational Phase 4 20537-88-6 2141
18
Diphenhydramine Approved, Investigational Phase 4 147-24-0, 58-73-1 3100
19
Promethazine Approved, Investigational Phase 4 60-87-7 4927
20
Histamine Approved, Investigational Phase 4 51-45-6 774
21
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
22
Aluminum hydroxide Approved, Investigational Phase 4 21645-51-2
23
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
24
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
25
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
26
Povidone Approved Phase 4 9003-39-8
27
Simethicone Approved Phase 4 8050-81-5
28
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
29
Castor oil Approved, Investigational, Nutraceutical, Vet_approved Phase 4 8001-79-4
30
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
31
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
32
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
33
Cyanocobalamin Approved, Nutraceutical Phase 4 68-19-9 44176380
34
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
35
Pyridoxine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 65-23-6 1054
36
Cobalamin Experimental Phase 4 13408-78-1 6857388
37 Calcium, Dietary Phase 4
38 Ionophores Phase 4
39 Anti-Infective Agents, Local Phase 4
40 Disinfectants Phase 4
41 Chlorhexidine gluconate Phase 4
42 Sodium hypochlorite Phase 4
43 Eusol Phase 4
44 Castor Phase 4
45 Epinephryl borate Phase 4
46 Ether Phase 4
47 Citrate Phase 4
48 Folic Acid Antagonists Phase 4
49 N-Methylaspartate Phase 4
50
Bilirubin Phase 4 635-65-4, 69853-43-6 5280352 21252250

Interventional clinical trials:

(show top 50) (show all 304)
# Name Status NCT ID Phase Drugs
1 Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer Unknown status NCT01876407 Phase 4
2 A Randomized Study on the Effects of Lactobacillus Brevis CD2 in the Prevention of Radio and Chemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients. Unknown status NCT01707641 Phase 4
3 Efficacy of Two Different Oral Hygiene Regimens on the Incidence and Severity of Oral Mucositis in Patients Receiving Hematopoietic Stem Cell Transplantation - A Randomized Controlled Trial Unknown status NCT02662374 Phase 4 .02% Chlorohexidine Gluconate;3% Sodium Bicarbonate;Nystatin 10000U/ml;Supersaturated Calcium Phosphate
4 Local Administration of Morphine: An Evaluation of the Analgesic Effect at Stomatitis in Children Completed NCT00357942 Phase 4 morphine solution for injection;Placebo;morphine mouthwash;Placebo
5 Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers: a Randomized Clinical Trial Completed NCT02642900 Phase 4 Nystatin 100.000 units
6 A Randomized, Double-blind Study to Evaluate the Efficacy of MuGard Mucoadhesive Oral Wound Rinse for the Amelioration of Oral Mucositis in Subjects Receiving Chemoradiation Therapy for the Treatment of Cancers of the Head and Neck Completed NCT01283906 Phase 4
7 Clinical Evaluation of an Experimental Solution Based on Ricinus Communis Compared to Sodium Hypochlorite for Denture Cleansing Completed NCT02407834 Phase 4
8 Evaluation of the Efficacy of a Hexetidine- and Chlorobutanol-based Mouthwash in the Symptomatic Treatment of Oral Lesions Due to Removable Prostheses: a Prospective, Randomized, Triple-blind Controlled Clinical Trial Completed NCT01115049 Phase 4 chlorobutanol, hexetidine;Chlorhexidine
9 Open-Label Single-Arm Phase IV Study of Pemetrexed in Taiwanese Patients With Advanced Non-Small Cell Lung Cancer Who Have Had Prior Chemotherapy Completed NCT00380718 Phase 4 pemetrexed
10 Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration Completed NCT00280514 Phase 4 cefpirome and moxifloxacin administration
11 Clinical Study of the Effects of Compound Kushen Injection on Radiation-induced Oral Mucositis in Head and Neck Cancer Patients. Recruiting NCT04204382 Phase 4 Levofloxacin injection;Compound kushen injection
12 Celiac Disease and Vitamin Status: Evaluation of the Effect of Supplementation With a Probiotic (VIVOMIXX®) on Vitamin B6, B12, 25'OH D, Folic Acid and Omocystein Levels, Metabolic and Inflammatory Status, and Gut Microbiota Metabolomics in a Cohoort of Celiac Patients Recruiting NCT04160767 Phase 4 Probiotic Vivomixx
13 Prospective, Open-label, Randomized, Control Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine Suspended NCT01288625 Phase 4 Amifostine
14 An Adaptive Design, Single-Blind, Randomized, Controlled Study Investigating Polyvinylpyrrolidone (PVP) and Sodium Hyaluronate-Containing Oral Gel (Gelclair®) in Comparison to Viscous Lidocaine, Diphenhydramine, and Aluminum-magnesium Hydroxide/Simethicone Antacid Suspension Mouthwash ("Magic Mouthwash") for the Management of Oral Mucositis Associated With High Dose Chemotherapy and Methotrexate in Allogeneic Stem Cell Transplant Recipients Terminated NCT03490396 Phase 4
15 Ketorolac for Analgesia followiNG Autologous Breast RecOnstructiOn Withdrawn NCT03007381 Phase 4 Ketorolac Tromethamine;Normal Saline
16 The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients Unknown status NCT01099891 Phase 3 rhEGF;Placebo
17 A Pilot Study on the Efficacy of Lactobacillus Brevis CD2 Lozenges in Preventing Oral Mucositis by High-dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation Unknown status NCT02085694 Phase 2, Phase 3 Lactobacillus brevis CD2
18 The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus. A Randomized Controlled Trial Unknown status NCT01083420 Phase 3 Minocycline;Dexamethasone
19 A Multinational, Multicenter, Double-Blind, Placebo-Controlled, Randomized, Phase III Clinical Trial to Determine the Efficacy and Safety of IB-367 Rinse in Reducing the Severity of Oral Mucositis in Patients Receiving Radiotherapy for Head and Neck Malignancy Unknown status NCT00022373 Phase 3 iseganan HCl oral solution
20 A Randomized, Double-Blind, Placebo-Controlled Pilot Study for Evaluating the Efficacy of the Homeopathic Remedy Traumeel S on Pain Reduction Following Tonsillectomy in Adult Patients. Unknown status NCT00410332 Phase 3 Traumeel S;Placebo
21 Laser Therapy Prevents Mucositis Oral in Patients Undergoing to Chemotherapy for Bone Marrow Transplantation? A Randomized Clinical Trial. Unknown status NCT02020928 Phase 3
22 Evaluation of Low-energy Laser Therapy for Prevention and Reduction of Severity of Oral Mucositis in Children "Mucositis Laser 1" Unknown status NCT01007617 Phase 2, Phase 3
23 Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic in Elderly People Completed NCT02818803 Phase 3 Miconazole
24 Prevention of Recurrent Aphthous Stomatitis Using Vitamins Completed NCT00527306 Phase 3
25 Effect of Low-level Laser Therapy on Inflammatory Mediators Release During Chemotherapy-induced Oral Mucositis: a Randomized Preliminary Study Completed NCT02050373 Phase 3
26 A Randomized,Controlled Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis. Completed NCT02303197 Phase 3 ChiNing decoction
27 Evaluating the Effectiveness of Topical Morphine Compared With a Routine Mouthwash in Managing Cancer Treatment-induced Mucositis in Patients With Head and Neck Cancer in Isfahan Completed NCT01837446 Phase 2, Phase 3 2% morphine solution;Magnesium aluminum hydroxide;2% viscous lidocaine;Diphenhydramine
28 A Double-Blind, Randomized, Vehicle-Controlled Study Comparing the Safety and Efficacy of Benzydamine HCl 0.15% Oral Rinse Including a Separate Open-Label Standard of Care Arm in Subjects With Radiation-Induced Mucositis Completed NCT00051441 Phase 3 Benzydamine Hydrochloride 0.15% Oral Rinse
29 LAMPO: Multicenter Randomized Double-blind Controlled Trial to Evaluate the Efficacy of Laser Therapy for Treatment of Oral Mucositis Induced by Chemotherapy in Children Completed NCT02762019 Phase 3
30 A Phase 3, Randomized, Double-blind, Placebo-controlled Trial of Recombinant Human Keratinocyte Growth Factor for Reduction of Mucositis in Patients With Hematologic Malignancies Undergoing Total Body Irradiation and High-dose Chemotherapy With Autologous PBPC Transplantation Completed NCT00041665 Phase 3 Recombinant Human Keratinocyte Growth Factor
31 A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2 Completed NCT00001812 Phase 3 Nystatin
32 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase III Clinical Study to Assess the Efficacy and Safety of SBG on Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT00790322 Phase 3 SBG
33 A Randomized, Blinded, Active-control Trial of Palifermin (rHuKGF) to Evaluate Oral Mucositis in Subjects With Hematologic Malignancies Undergoing Fractionated Total Body Irradiation (fTBI) and High Dose Chemotherapy With Autologous Peripheral Blood Progenitor Cell (PBPC) Transplantation Completed NCT00109031 Phase 3 palifermin;Cyclophosphamide;Etoposide;Placebo
34 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Radiotherapy With Concurrent Chemotherapy (RT/CT) Completed NCT00101582 Phase 3 Placebo;palifermin;cisplatin chemotherapy
35 A Phase II/III Blinded Randomized Trial to Determine the Efficacy of Low Energy Diode Laser Therapy (650 nm or 780 nm) to Prevent Oral Mucositis Following Bone Marrow Transplantation Completed NCT00024037 Phase 2, Phase 3
36 [rVSVΔG-ZEBOV] Ebola Prevention Vaccine Evaluation in Sierra Leone Completed NCT02378753 Phase 2, Phase 3
37 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Adjuvant Radiotherapy and Chemotherapy(RT/CT) Completed NCT00131638 Phase 3 Placebo;Palifermin
38 Evaluation of Oral Care to Prevent Oral Mucositis in Estrogen Receptor Positive Metastatic Breast Cancer Patients Treated With Everolimus: Phase III Randomized Control Trial Completed NCT02376985 Phase 3 Everolimus
39 A Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Palifermin (Recombinant Human Keratinocyte Growth Factor) for Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer Receiving 5-FU and Leucovorin as Adjuvant Therapy Completed NCT00393822 Phase 2, Phase 3 palifermin;placebo
40 Evaluate Safety and Tolerability and Compare Absorption/Distribution Kinetics of a Single 100 Mcg Dose of Fentanyl Sublingual Spray (Fentanyl SL Spray) in Cancer Subjects With or Without Oral Mucositis Completed NCT00956254 Phase 3 Fentanyl sublingual spray
41 A Double-Blind, Randomized, Placebo-controlled Study of Two Different Schedules of Palifermin for Reduction in Severity of Oral Mucositis in Subjects With Multiple Myeloma Receiving Melphalan Followed by Autologous Blood Stem Cell Transplantation Completed NCT00434161 Phase 3 Palifermin before only;Placebo;Palifermin before and after
42 Phase III Trial of Low-level Laser Therapy to Prevent Induced Oral Mucositis in Head and Neck Cancer Patients Submitted to Concurrent Chemoradiation Completed NCT01439724 Phase 3
43 Khon Kaen University Ethics Committee in Human Research Completed NCT02536781 Phase 2, Phase 3 Anthocyanin;Placebo
44 Clinical Phase III Trial to Compare Treosulfan-based Conditioning Therapy With Busulfan-based Reduced-intensity Conditioning (RIC) Prior to Allogeneic Haematopoietic Stem Cell Transplantation in Patients With AML or MDS Considered Ineligible to Standard Conditioning Regimens Completed NCT00822393 Phase 3 Busulfan;Treosulfan
45 A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer Completed NCT00615420 Phase 3
46 Effect of Ascorbic Acid Oral Supplementation in Assessing the Severity of Oral Mucositis in Chemo-radiation Therapy of Head and Neck Cancers. Completed NCT02868151 Phase 2, Phase 3 Ascorbic Acid;Zinc acetate
47 Phase III Randomized Double-blind Cross-over Trial of Caphosol® Versus NaCl 0.9% in the Relief of Oral Mucositis in Renal Cell Carcinoma, Hepatocellular Carcinoma, and Gastrointestinal Stromal Tumor Patients Receiving Targeted Therapy Completed NCT01265810 Phase 3
48 A Multi-Center, Randomized, Double-blind, Placebo-controlled Study of Adalimumab for the Maintenance of Clinical Remission in Japanese Subjects With Crohn's Disease Completed NCT00445432 Phase 2, Phase 3
49 A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy Completed NCT02229539 Phase 3 doxepin hydrochloride oral solution;DLA (diphenhydramine, lidocaine and antacids) rinse
50 A Comparison of Acute Oral Mucositis Between Morning and Afternoon Radiotherapy in Patients Receiving Radiation Treatment for Cancer of the Head and Neck Completed NCT00004234 Phase 3

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


carbamide peroxide
Sucralfate

Cochrane evidence based reviews: stomatitis

Sources

Genetic Tests for Stomatitis

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Anatomical Context for Stomatitis

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MalaCards organs/tissues related to Stomatitis:

40
Breast, T Cells, Lung, Bone, Bone Marrow, Kidney, Skin
Sources

Publications for Stomatitis

About this section

Articles related to Stomatitis:

(show top 50) (show all 14309)
# Title Authors PMID Year
1
A phase I and pharmacokinetic study of OSI-7904L, a liposomal thymidylate synthase inhibitor in combination with oxaliplatin in patients with advanced colorectal cancer. 54 61
17520255 2008
2
DPYD*2A mutation: the most common mutation associated with DPD deficiency. 54 61
17165084 2007
3
Phase II trial of pralatrexate (10-propargyl-10-deazaaminopterin, PDX) in patients with unresectable malignant pleural mesothelioma. 54 61
17409804 2007
4
First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. 54 61
15550581 2004
5
Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy. 54 61
15539918 2004
6
Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients. 54 61
12352929 2002
7
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. 54 61
10473079 1999
8
Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy. 54 61
9007910 1997
9
High dose busulphan/cyclophosphamide for autologous bone marrow transplantation is associated with minimal non-hemopoietic toxicity. 54 61
7524888 1994
10
Glucosamine promotes hepatitis B virus replication through its dual effects in suppressing autophagic degradation and inhibiting MTORC1 signaling. 61
31204557 2020
11
Dosing and Re-Administration of Lentiviral Vector for In Vivo Gene Therapy in Rhesus Monkeys and ADA-Deficient Mice. 61
31871959 2020
12
Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9. 61
31930167 2020
13
Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome: A debate about diagnosis and treatment in children continues. 61
31866107 2020
14
The immunology of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; what can the tonsils reveal. A literature review. 61
31786522 2020
15
LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. 61
31068071 2020
16
Efficient inactivation of pseudotyped HIV-based lentiviral vectors and infectious HIV. 61
31704112 2020
17
Allergic contact stomatitis caused by (meth)acrylates in an occlusal splint. 61
31515815 2020
18
Do Heavy Metals Accumulated in Saliva Involve in the Etiopathogenesis of Recurrent Aphthous Stomatitis? 61
32030633 2020
19
Depression Symptoms and recurrent aphthous stomatitis - evidence from a population-based study in Indonesia. 61
32031742 2020
20
Serotonin transporter gene (SLC6A4) variability in patients with recurrent aphthous stomatitis. 61
31846848 2020
21
The Impact of Nicotine and Cigarette Smoke Condensate on Metabolic Activity and Biofilm Formation of Candida albicans on Acrylic Denture Material. 61
30028051 2020
22
Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection. 61
32033109 2020
23
Validation of the HADS and PSS-10 and a cross-sectional study of psychological status in patients with recurrent aphthous stomatitis. 61
31919894 2020
24
Immunopathogenesis of canine chronic ulcerative stomatitis. 61
31923271 2020
25
Safety and immunogenicity of a highly attenuated rVSVN4CT1-EBOVGP1 Ebola virus vaccine: a randomised, double-blind, placebo-controlled, phase 1 clinical trial. 61
31952923 2020
26
Immune Effects of M51R Vesicular Stomatitis Virus Treatment of Carcinomatosis From Colon Cancer. 61
31415934 2020
27
Salivary levels of IgE and ECP in patients with recurrent aphthous stomatitis. 61
31976038 2020
28
Properties of fucoidans beneficial to oral healthcare. 61
31214896 2020
29
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death. 61
31820871 2020
30
Optimized pre-clinical grade production of two novel lentiviral vector pseudotypes for lung gene delivery. 61
32000531 2020
31
Recycling endosomes attach to the trans-side of Golgi stacks in Drosophila and mammalian cells. 61
31974113 2020
32
Collective Viral Spread Mediated by Virion Aggregates Promotes the Evolution of Defective Interfering Particles. 61
31911487 2020
33
Anti-inflammatory potential of an essential oil-containing mouthwash in elderly subjects enrolled in supportive periodontal therapy: a 6-week randomised controlled clinical trial. 61
31916036 2020
34
Lesions Observed Post Mortem in Post-hatchling Loggerhead Sea Turtles (Caretta caretta) from a Head Start Programme. 61
31955806 2020
35
The Propagation and Quantification of Two Emerging Oncolytic Viruses: Vesicular Stomatitis (VSV) and Zika (ZIKV). 61
31776931 2020
36
The efficacy and toxicity of 4-day chemotherapy with methotrexate, etoposide and actinomycin D in patients with choriocarcinoma and high-risk gestational trophoblastic neoplasia. 61
31520175 2020
37
Timeliness of vesicular disease notification system in Brazilian foot-and-mouth disease surveillance programme. 61
31965759 2020
38
Safety and immunogenicity of vesicular stomatitis virus-based vaccines for Ebola virus disease. 61
31952924 2020
39
Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X™ hydro fixed-bed. 61
32006630 2020
40
A single dose of a vesicular stomatitis virus-based influenza vaccine confers rapid protection against H5 viruses from different clades. 61
31934358 2020
41
Gene variability in matrix metalloproteinases in patients with recurrent aphthous stomatitis. 61
31968135 2020
42
Probiotics for recurrent idiopathic aphthous stomatitis in adults: a placebo-controlled randomized trial. 61
31954066 2020
43
LncRNA CASC 2 is upregulated in aphthous stomatitis and predicts the recurrence. 61
31937279 2020
44
Association between the promoter region of serotonin transporter polymorphisms and recurrent aphthous stomatitis: A meta-analysis. 61
31550570 2020
45
Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. 61
31914397 2020
46
The Connector Domain of Vesicular Stomatitis Virus Large Protein Interacts with the Viral Phosphoprotein. 61
31896592 2020
47
Impact of dextran sulfate in culture media on titration of vesicular stomatitis virus. 61
31678047 2020
48
Serum prolidase and oxidative stress levels in patients with recurrent aphthous stomatitis: a prospective, controlled study. 61
31249217 2020
49
Detection and first molecular characterization of bovine papular stomatitis virus in dairy calves in Argentina. 61
31359355 2020
50
Poxviruses diagnosed in cattle from Distrito Federal, Brazil (2015-2018). 61
31971341 2020
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Variations for Stomatitis

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Expression for Stomatitis

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Search GEO for disease gene expression data for Stomatitis.
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Pathways for Stomatitis

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Pathways related to Stomatitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Innate Immune System 65
Show member pathways
 13.72 UBA52 RSAD2 NUP98 IFNA2 IFITM3 IFITM2
2
Cytokine Signaling in Immune system 65
Show member pathways
 12.88 UBA52 RSAD2 NUP98 IFNA2 IFITM3 IFITM2
3
Measles 36
Show member pathways
 12.59 RSAD2 NUP98 IFNA2 EIF2AK2 DDX58 ADAR
4
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways 65
Show member pathways
 12.51 UBA52 IFNA2 DDX58 ATG5 ATG12 ADAR
5
Immune response IFN alpha/beta signaling pathway 22
Show member pathways
 12.08 RSAD2 IFNA2 IFITM3 IFITM2 FGF7 BST2
6
Interferon gamma signaling 65
Show member pathways
 11.81 UBA52 RSAD2 NUP98 IFNA2 IFITM3 IFITM2
7
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.72 IFNA2 CSF3 CSF2
8
Lung fibrosis 1
11.43 FGF7 CSF3 CSF2
9
Pink/Parkin Mediated Mitophagy 65
Show member pathways
 11.27 UBA52 ATG5 ATG12
10
Peginterferon alpha-2a/Peginterferon alpha-2b Pathway (Hepatocyte), Pharmacodynamics 60
Show member pathways
 10.82 IFNA2 EIF2AK2 DDX58 ADAR
Sources

GO Terms for Stomatitis

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Cellular components related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phagophore assembly site membrane GO:0034045 8.96 ATG5 ATG12
2 Atg12-Atg5-Atg16 complex GO:0034274 8.62 ATG5 ATG12

Biological processes related to Stomatitis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 innate immune response GO:0045087 9.95 RSAD2 IFITM3 IFITM2 EIF2AK2 DDX58 BST2
2 immune system process GO:0002376 9.93 RSAD2 EIF2AK2 DDX58 ATG5 ADAR
3 viral process GO:0016032 9.89 RSAD2 NUP98 LDLR EIF2AK2 DDX58
4 cytokine-mediated signaling pathway GO:0019221 9.83 UBA52 IFNA2 CSF3 CSF2
5 defense response to virus GO:0051607 9.76 RSAD2 IFNA2 IFITM3 IFITM2 EIF2AK2 DDX58
6 type I interferon signaling pathway GO:0060337 9.73 RSAD2 IFNA2 IFITM3 IFITM2 BST2 ADAR
7 negative regulation of viral genome replication GO:0045071 9.72 RSAD2 IFITM3 IFITM2 EIF2AK2 BST2
8 response to interferon-gamma GO:0034341 9.63 IFITM3 IFITM2 BST2
9 negative regulation of viral entry into host cell GO:0046597 9.61 IFNA2 IFITM3 IFITM2
10 response to interferon-beta GO:0035456 9.54 IFITM3 IFITM2 BST2
11 positive regulation of keratinocyte proliferation GO:0010838 9.51 TP63 FGF7
12 response to virus GO:0009615 9.5 RSAD2 IFITM3 IFITM2 EIF2AK2 DDX58 BST2
13 C-terminal protein lipidation GO:0006501 9.48 ATG5 ATG12
14 response to interferon-alpha GO:0035455 9.02 IFITM3 IFITM2 EIF2AK2 BST2 ADAR

Molecular functions related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.09 UBA52 TP63 RSAD2 NUP98 LDLR IFNA2
2 double-stranded RNA binding GO:0003725 9.13 EIF2AK2 DDX58 ADAR
3 Atg8 ligase activity GO:0019776 8.62 ATG5 ATG12
Sources

Sources for Stomatitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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