Stomatitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: STM007 MIFTS: 52	Stomatitis Categories: Oral diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Download Expand all tables

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Aliases & Classifications for Stomatitis

MalaCards integrated aliases for Stomatitis:

Name: Stomatitis ¹² ⁷⁶ ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Oral diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the digestive system

Diseases of oral cavity, salivary glands and jaws

Stomatitis and related lesions

Other forms of stomatitis

External Ids:

Disease Ontology ¹² DOID:9637

ICD10 ³³ K12.1

MeSH ⁴⁴ D013280

NCIt ⁵⁰ C26887

SNOMED-CT ⁶⁸ 155660009 196527002 61170000 more

UMLS ⁷³ C0038362

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Summaries for Stomatitis

MalaCards based summary : Stomatitis is related to measles and chikungunya, and has symptoms including enanthema, oral manifestations and oral pain. An important gene associated with Stomatitis is LDLR (Low Density Lipoprotein Receptor), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ephedrine and Pseudoephedrine have been mentioned in the context of this disorder. Affiliated tissues include bone, t cells and lung, and related phenotype is immune system.

Wikipedia : ⁷⁶ Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

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Related Diseases for Stomatitis

Diseases related to Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 201)

#	Related Disease	Score	Top Affiliating Genes
1	measles	30.3	ADAR DDX58 EIF2AK2
2	chikungunya	30.1	BST2 DDX58 RSAD2
3	influenza	30.0	DDX58 EIF2AK2 IFITM2 IFITM3 RSAD2
4	hepatitis	29.9	DDX58 EIF2AK2 IFNA2 LDLR
5	hepatitis c	29.7	DDX58 EIF2AK2 IFNA2 LDLR
6	hepatitis c virus	28.7	ADAR ATG5 BST2 DDX58 EIF2AK2 HNRNPK
7	aphthous stomatitis	12.4
8	periodic fever, aphthous stomatitis, pharyngitis and adenitis	12.4
9	denture stomatitis	12.3
10	ulcerative stomatitis	12.3
11	sutton disease 2	11.9
12	noma	11.4
13	hand, foot and mouth disease	11.2
14	angular cheilitis	11.2
15	necrotizing ulcerative gingivitis	11.2
16	glucagonoma	11.2
17	methylmalonic aciduria and homocystinuria, cblf type	10.9
18	pharyngitis	10.5
19	oral candidiasis	10.4
20	cervicitis	10.4
21	cervical adenitis	10.3
22	dengue virus	10.3	DDX58 IFITM2 IFITM3 RSAD2
23	west nile virus	10.3	DDX58 IFITM2 IFITM3 RSAD2
24	mucositis	10.1
25	engraftment syndrome	10.0	CSF2 CSF3
26	viral infectious disease	10.0	DDX58 EIF2AK2 IFNA2
27	lichen planus	10.0
28	glossitis	10.0
29	trichosporonosis	10.0	CSF2 CSF3
30	aging	10.0
31	encephalitis	10.0
32	oral lichen planus	10.0
33	celiac disease 1	9.9
34	gingivitis	9.9
35	periodontitis	9.9
36	herpes simplex	9.9
37	anxiety	9.9
38	leukemia	9.9
39	cheilitis	9.9
40	adenocarcinoma	9.9
41	uvulitis	9.9
42	human t-cell leukemia virus type 2	9.9	ADAR CSF2
43	vaccinia	9.9
44	pancreatitis	9.9
45	felty syndrome	9.8	CSF2 CSF3
46	human immunodeficiency virus type 1	9.8
47	tonsillitis	9.8
48	prostatitis	9.8
49	central nervous system disease	9.8
50	neuronitis	9.8

Graphical network of the top 20 diseases related to Stomatitis:

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Symptoms & Phenotypes for Stomatitis

UMLS symptoms related to Stomatitis:

enanthema, oral manifestations, oral pain, burning mucosal, sore roof of mouth (symptom), oral mucosal blisters

MGI Mouse Phenotypes related to Stomatitis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system	MP:0005387	9.36	ADAR ATG5 CSF2 CSF3 DDX58 EIF2AK2

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Drugs & Therapeutics for Stomatitis

Drugs for Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 432)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Ephedrine

Approved

Phase 4,Phase 1,Phase 2

299-42-3

9294

Pseudoephedrine

Approved

Phase 4,Phase 1,Phase 2

90-82-4

7028

Miconazole

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

22916-47-8

4189

Morphine

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

57-27-2

5288826

Docetaxel

Approved, Investigational

Phase 4,Phase 3,Phase 2

114977-28-5

148124

Nystatin

Approved, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1

1400-61-9

11953884

Zinc

Approved, Investigational

Phase 4,Phase 2,Phase 3,Early Phase 1

7440-66-6

23994

Lenograstim

Approved, Investigational

Phase 4,Phase 3,Phase 2

135968-09-1

Methylene blue

Approved, Investigational

Phase 4,Phase 3

61-73-4

Infliximab

Approved

Phase 4,Phase 2,Phase 1

170277-31-3

Everolimus

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

159351-69-6

6442177

Tacrolimus

Approved, Investigational

Phase 4,Phase 3,Phase 2

104987-11-3

445643 439492

Chlorhexidine

Approved, Vet_approved

Phase 4,Phase 2,Not Applicable

55-56-1

9552079 2713

Melphalan

Approved

Phase 4,Phase 3,Phase 2,Not Applicable

148-82-3

4053 460612

Ethanol

Approved

Phase 4,Phase 2,Phase 1

64-17-5

702

Epinephrine

Approved, Vet_approved

Phase 4,Phase 1

51-43-4

5816

Pemetrexed

Approved, Investigational

Phase 4,Phase 3

150399-23-8, 137281-23-3

446556 60843

Sirolimus

Approved, Investigational

Phase 4,Phase 3,Phase 2,Not Applicable

53123-88-9

5284616 6436030 46835353

Hexetidine

Approved, Investigational

Phase 4

141-94-6

Racepinephrine

Approved

Phase 4,Phase 1

329-65-7

838

Iron

Approved

Phase 4

7439-89-6

23925

Deferasirox

Approved, Investigational

Phase 4

201530-41-8

5493381

Amifostine

Approved, Investigational

Phase 4,Phase 2

20537-88-6

2141

leucovorin

Approved, Nutraceutical

Phase 4,Phase 2,Phase 3,Phase 1

58-05-9

143 6006

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

59-30-3

6037

Vitamin C

Approved, Nutraceutical

Phase 4,Phase 2,Phase 3

50-81-7

5785 54670067

Citric Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 3

77-92-9

311

Castor oil

Approved, Investigational, Nutraceutical, Vet_approved

Phase 4

8001-79-4

Bilirubin

Phase 4,Phase 2

635-65-4

5280352

Analgesics

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Respiratory System Agents

Phase 4,Phase 2,Phase 1,Not Applicable

Central Nervous System Depressants

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Adjuvants, Immunologic

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Micronutrients

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Folic Acid Antagonists

Phase 4,Phase 2,Phase 3,Phase 1

Mitogens

Phase 4,Phase 3,Phase 2,Phase 1

Gastrointestinal Agents

Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1

Narcotics

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Nasal Decongestants

Phase 4,Phase 1,Phase 2

Tetrahydrozoline

Phase 4

Analgesics, Opioid

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

N-Methylaspartate

Phase 4,Phase 3,Phase 2

Dermatologic Agents

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

Trace Elements

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Nucleic Acid Synthesis Inhibitors

Phase 4,Phase 2,Phase 3

Ophthalmic Solutions

Phase 4

Vasoconstrictor Agents

Phase 4,Phase 1,Phase 2

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Vitamin B Complex

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 405)

#	Name	Status	NCT ID	Phase	Drugs
1	Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer	Unknown status	NCT01876407	Phase 4
2	Oral Hygiene Regimen in Patients on HCT	Unknown status	NCT02662374	Phase 4	.02% Chlorohexidine Gluconate;3% Sodium Bicarbonate;Nystatin 10000U/ml;Supersaturated Calcium Phosphate
3	A Study to Evaluate the Efficacy of MuGard for the Amelioration of Oral Mucositis in Head and Neck Cancer Patients	Completed	NCT01283906	Phase 4
4	Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy	Completed	NCT00357942	Phase 4	morphine solution for injection;Placebo;morphine mouthwash;Placebo
5	Effectiveness of Hygiene Solutions on Denture Biofilm	Completed	NCT02407834	Phase 4
6	PROMPT - Palifermin in Reduction of Oral Mucositis in PBSC Transplantation	Completed	NCT00352703	Phase 4	Kepivance (Palifermin)
7	Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers	Completed	NCT02642900	Phase 4	Nystatin 100.000 units
8	Hexetidine and Chlorobutanol for Lesions Due to Prostheses	Completed	NCT01115049	Phase 4	chlorobutanol, hexetidine;Chlorhexidine
9	A Clinical Trial of Patients With Solid Tumours Receiving Granulocyte Colony Stimulating Factor as Primary Prophylaxis for Chemotherapy-induced Neutropenia, in a Docetaxel Based Regimen	Completed	NCT01107756	Phase 4	LENOGRASTIM (GRANOGYTE 34)
10	Chemotherapy for Patients With Non-Small Cell Lung Cancer	Completed	NCT00380718	Phase 4	pemetrexed
11	Oral Zinc Therapy for the Prevention of Mucositis	Completed	NCT00449592	Phase 4	Zinc;Placebo
12	Safety Study of MK-3641 and MK-7243 Co-administered in Adult Participants With Ragweed and Grass Pollen Induced Allergic Rhinitis (P08607, MK-3641-006)	Completed	NCT02256553	Phase 4	Rescue Medication
13	Study Evaluating A Planned Transition From Tacrolimus To Sirolimus In Kidney Transplant Recipients	Completed	NCT00895583	Phase 4	Tacrolimus;Sirolimus;Tacrolimus
14	Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery	Completed	NCT00688636	Phase 4	infliximab;placebo
15	Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye	Completed	NCT01488396	Phase 4	0.05%cyclosporin eye drop
16	Gelclair at Conditioning or After Oral Mucositis Diagnosed vs. Magic Mouth Wash in Stem Cell Transplant Recipients	Recruiting	NCT03490396	Phase 4
17	Effect of Lactobacillus Brevis CD2 in Prevention of Radio-chemotherapy Induced Oral Mucositis in Head and Neck Cancer	Recruiting	NCT01707641	Phase 4
18	A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients	Recruiting	NCT02948699	Phase 4
19	Safety Study of Crushed Deferasirox Film Coated Tablets in Pediatric Patients With Transfusional Hemosiderosis	Recruiting	NCT03372083	Phase 4	Deferasirox
20	G-CSF in the Treatment of Toxic Epidermal Necrolysis	Recruiting	NCT02739295	Phase 4	recombinant granulocyte - colony stimulating factor;NaCl 0.9%
21	Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older	Active, not recruiting	NCT02514174	Phase 4	Afatinib
22	Prospective Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine	Suspended	NCT01288625	Phase 4	Amifostine
23	Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3)	Terminated	NCT02695290	Phase 4	Afatinib
24	The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients	Unknown status	NCT01099891	Phase 3	rhEGF;Placebo
25	Low-energy Laser Therapy for Prevention of Oral Mucositis in Children	Unknown status	NCT01007617	Phase 2, Phase 3
26	Lactobacillus Brevis CD2 Preventing Oral Mucositis	Unknown status	NCT02085694	Phase 2, Phase 3	Lactobacillus brevis CD2
27	Palifermin for Patients Receiving Hematopoietic Stem Cell Transplantation	Unknown status	NCT02313792	Phase 3	Palifermin
28	Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer	Unknown status	NCT00022373	Phase 3	iseganan HCl oral solution
29	Laser Therapy Prevents Mucositis Oral in Chemotherapy for Bone Marrow Transplantation?	Unknown status	NCT02020928	Phase 3
30	Oral Glutamine and Mucositis of Head and Neck Cancer Patients Undergoing Radiation	Unknown status	NCT02282839	Phase 3
31	Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults	Unknown status	NCT02173756	Phase 3	morphine gel;placebo gel
32	The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcome	Unknown status	NCT02506231	Phase 2, Phase 3	Folinic acid;Placebo
33	The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus	Unknown status	NCT01083420	Phase 3	Minocycline;Dexamethasone
34	Traumeel for Post-Tonsillectomy Pain	Unknown status	NCT00410332	Phase 3	Traumeel S;Placebo
35	COX-2 Inhibitor With Concurrent Chemoradiation in Locally Advanced Head & Neck Carcinoma	Unknown status	NCT00603759	Phase 3	celecoxib;placebo
36	Safety and Efficacy Study of Ara-c at 18 gm/m2 Versus 12 gm/m2 for 3 Cycles Each in AML Consolidation	Unknown status	NCT01615757	Phase 3	Ara-c;Ara-c
37	Laser for Oral Mucositis in Pediatric Onco-hematology	Completed	NCT02762019	Phase 3
38	Prevention of Recurrent Aphthous Stomatitis Using Vitamins	Completed	NCT00527306	Phase 3
39	Low-level Laser Therapy to Prevent Oral Mucositis in Head and Neck Patients	Completed	NCT01439724	Phase 3
40	Low-level Laser Therapy on Inflammatory Mediators During Chemotherapy-induced Oral Mucositis	Completed	NCT02050373	Phase 3
41	Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis	Completed	NCT02303197	Phase 3	ChiNing decoction
42	Oral Mucositis and Laser Therapy Associated With Photodynamic Therapy	Completed	NCT02555501	Phase 3
43	Safety & Efficacy Study of Benzydamine Oral Rinse for the Treatment of Oral Mucositis (Mouth Sores) Resulting From Radiation Therapy for Cancer of the Oral Cavity, Oropharynx, or Nasopharynx	Completed	NCT00051441	Phase 3	Benzydamine Hydrochloride 0.15% Oral Rinse
44	Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer	Completed	NCT00101582	Phase 3	Placebo;palifermin;cisplatin chemotherapy
45	Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy	Completed	NCT02229539	Phase 3	doxepin hydrochloride oral solution;DLA (diphenhydramine, lidocaine and antacids) rinse
46	Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer	Completed	NCT01837446	Phase 2, Phase 3	2% morphine solution;Magnesium aluminum hydroxide;2% viscous lidocaine;Diphenhydramine
47	Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)	Completed	NCT00109031	Phase 3	palifermin;Cyclophosphamide;Etoposide;Placebo
48	A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer	Completed	NCT00393822	Phase 2, Phase 3	palifermin;placebo
49	A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer	Completed	NCT00131638	Phase 3	Placebo;Palifermin
50	Curcumin for Prevention of Oral Mucositis in Children Chemotherapy	Completed	NCT00475683	Phase 3

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :

carbamide peroxide

sucralfate

Cochrane evidence based reviews: stomatitis

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Genetic Tests for Stomatitis

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Anatomical Context for Stomatitis

MalaCards organs/tissues related to Stomatitis:

⁴¹

Bone, T Cells, Lung, Eye, Bone Marrow, Kidney, Myeloid

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Publications for Stomatitis

Articles related to Stomatitis:

(show top 50) (show all 1533)

#	Title	Authors	Year
1	Stomatitis associated with mammalian target of rapamycin inhibition: A review of pathogenesis, prevention, treatment, and clinical implications for oral practice in metastatic breastA cancer. ( 29439772 )	Chambers M.S....Meiller T.F.	2018
2	Association of Serotonin Transporter Gene Polymorphism with Recurrent Aphthous Stomatitis. ( 29296268 )	Najafi S....Rezaei N.	2018
3	Fulminant presentation of oral mucosal leishmaniasis as severe stomatitis and periodontitis. ( 29380732 )	de Ruiter M.H.T....Grobusch M.P.	2018
4	Tonsillar antimicrobial peptide (AMP) expression profiles of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) patients. ( 29859567 )	Gazi U....Bahceciler N.O.	2018
5	Characterization of Herbal Antifungal Agent, <i>Origanum vulgare</i> against Oral <i>Candida</i> spp. Isolated from Patients with <i>Candida</i>-Associated Denture Stomatitis: An <i>In vitro</i> Study. ( 29962756 )	Bhat V....Balaji S.	2018
6	Prevalence and psychological stress in recurrent aphthous stomatitis among female dental students in Saudi Arabia. ( 29785161 )	Ajmal M....Al-Qarni H.	2018
7	Allergic contact stomatitis caused by propolis candies. ( 29411380 )	MartA-nez PallA!s I....Prieto Torres L.	2018
8	The association between minor recurrent aphthous stomatitis (RAS), children's poor oral condition, and underlying negativeA psychosocial habits and attitudes towards oral hygiene. ( 29653566 )	Tecco S....Gherlone E.F.	2018
9	Comorbidity of PFAPA (periodic fever, aphthous stomatitis, pharyngitis and adenitis) patients: a case control study. ( 29533751 )	Lantto U....Renko M.	2018
10	Role of laser or photodynamic therapy in treatment of denture stomatitis: A systematic review. ( 29807743 )	Davoudi A....Nosouhian S.	2018
11	An international delphi survey for the definition of the variables for the development of new classification criteria for periodic fever aphtous stomatitis pharingitis cervical adenitis (PFAPA). ( 29669569 )	Vanoni F....Hofer M.	2018
12	Severe Airflow Obstruction in a Man with Stomatitis and Lymphadenopathy. ( 29286849 )	Krishna R....Summer R.	2018
13	Vesicular stomatitis forecasting based on Google Trends. ( 29385198 )	Wang J....Niu B.	2018
14	Gastric parietal cell and thyroid autoantibodies in recurrent aphthous stomatitis patients with concomitant oral lichen planus. ( 29753458 )	Wu Y.C....Sun A.	2018
15	Immunogenicity of propagation-restricted vesicular stomatitis virus encoding Ebola virus glycoprotein in guinea pigs. ( 29869979 )	Locher S....Zimmer G.	2018
16	Identification of bacteria present in ulcerative stomatitis lesions of captive sea turtles Chelonia mydas. ( 29934703 )	Vega-Manriquez D.X....MuA+oz-TenerA-a F.A.	2018
17	Autosomal dominant deficiency of the interleukin-17F in recurrent aphthous stomatitis: Possible novel mutation in a new entity. ( 29458167 )	Zare Bidoki A....Rezaei N.	2018
18	Control of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Eliminating Envelope Protein-Positive Cells with Recombinant Vesicular Stomatitis Viruses Encoding HTLV-1 Primary Receptor. ( 29212930 )	Tezuka K....Hamaguchi I.	2018
19	Management of denture stomatitis: a narrative review. ( 29460527 )	Di Stasio D....Lucchese A.	2018
20	Cytokine gene polymorphism in denture stomatitis patients: A clinical study. ( 29423993 )	KeA9oA9lu A.C....Bilhan H.	2018
21	Mycoplasma pneumoniae-associated mucositis with severe blistering stomatitis and pneumonia successfully treated with azithromycin and infusion therapy. ( 29952018 )	Demitsu T....Jinbu Y.	2018
22	Associations of IL-1, 6, and 10 Gene Polymorphisms with Susceptibility to Recurrent Aphthous Stomatitis: Insights from a Meta-Analysis. ( 29641282 )	Chen L....Zhang J.	2018
23	Risk factors for periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: a case-control study. ( 29799086 )	Kettunen S....Renko M.	2018
24	Photodynamic inactivation of Candida ssp. on denture stomatitis. A clinical trial involving palatal mucosa and prosthesis disinfection. ( 29678677 )	de Senna A.M....Ribeiro M.S.	2018
25	Association between interleukin family gene polymorphisms and recurrent aphthous stomatitis risk. ( 29550839 )	Zhou Y....Sun M.	2018
26	Association of the nod-like receptor 3 (NLRP3) gene variability with recurrent aphthous stomatitis in the Czech population. ( 29430721 )	Slezakova S....Izakovicova Holla L.	2018
27	Porcine monocyte-derived dendritic cells can be differentially activated by vesicular stomatitis virus and its matrix protein mutants. ( 29778202 )	Sun G....Sun T.	2018
28	In Vitro Antifungal Susceptibility of <i>Candida</i> Species Isolated from Iranian Patients with Denture Stomatitis. ( 29888258 )	Mahdavi Omran S....Taghizadeh-Armaki M.	2018
29	The First International Conference on Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome. ( 29246466 )	Harel L....Marshall G.S.	2018
30	Healthy lifestyle habits benefit remission of recurrent aphthous stomatitis and RAS type ulceration. ( 29327722 )	Ge L.	2018
31	Pregnancy complicated with PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) syndrome: a case report. ( 29866074 )	Ota K....Mizunuma H.	2018
32	The role of tonsillectomy in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome; a literature review. ( 29483843 )	FA...A9ymar K.	2018
33	A polyamide inhibits replication of vesicular stomatitis virus by targeting RNA in the nucleocapsid. ( 29437970 )	Gumpper R.H....Luo M.	2018
34	Hematinic dei-8ciencies in patients with recurrent aphthous stomatitis: variations by gender and age. ( 29476670 )	Bao Z.X....Liu L.X.	2018
35	Salivary levels of TNF-I+ in patients with recurrent aphthous stomatitis: A cross-sectional study. ( 29732020 )	Chaudhuri K....Ashok L.	2018
36	Relationship between salivary calprotectin levels and recurrent aphthous stomatitis: A preliminary study. ( 29519972 )	Koray M....Saruhanoglu A.	2018
37	The Development of a Novel Diagnostic Assay That Utilizes a Pseudotyped Vesicular Stomatitis Virus for the Detection of Neutralizing Activity against Crimean-Congo Hemorrhagic Fever Virus. ( 29709967 )	Suda Y....Shimojima M.	2018
38	Examination of serum hematinics and autoantibodies is important for treatment of recurrent aphthous stomatitis. ( 29336939 )	Chiang C.P....Sun A.	2018
39	Recurrent aphtous stomatitis. ( 29332375 )	Giannetti L....Lo Muzio L.	2018
40	The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials. ( 29757706 )	Suder E....de Wit E.	2018
41	Immune Consequences of in vitro Infection of Human Peripheral Blood Leukocytes with Vesicular Stomatitis Virus. ( 29306950 )	Tomczyk T....Orzechowska B.U.	2018
42	Susceptibility of Zebrafish to Vesicular Stomatitis Virus Infection. ( 29304309 )	Guerra-Varela J....SA!nchez L.	2018
43	Analysis of Dietary Related Factors of Recurrent Aphthous Stomatitis among College Students. ( 29681971 )	Du Q....Liu S.	2018
44	Risk factors associated with clinical signs of vesicular stomatitis and seroconversion without clinical disease in Colorado horses during the 2014 outbreak. ( 29891143 )	Urie N.J....Schiltz J.J.	2018
45	Haematinic deficiencies and patient clinical profiles in Polish patients with recurrent aphthous stomatitis (RAS). ( 29499093 )	A9lebioda Z....Dorocka-Bobkowska B.	2018
46	The association between interleukin polymorphism and recurrent aphthous stomatitis: A meta-analysis. ( 29800802 )	Wu D....Zhou P.	2018
47	Polyvalent immunoglobulins with vitamin D3 and vitamin B12 in the treatment of Sjogren's syndrome in a vegetarian with stomatitis, glossodynia, xerostomia, and elevated antinuclear antibodies: Case reporta8c. ( 29231165 )	Cuny C....Woodcock B.G.	2018
48	Evidence that Enterobius vermicularis plays a causative role for PFAPA and recurrent aphthous stomatitis. ( 29856193 )	Polese L....PalA^ G.	2018
49	Evaluation and Comparison of Total Antioxidant Capacity of Saliva Between Patients with Recurrent Aphthous Stomatitis and Healthy Subjects. ( 29755602 )	Rezaei F....Soltani T.	2018
50	The severity of denture stomatitis as related to risk factors and different Candida spp. ( 29759652 )	PeriA8 M....ArsiA8 ArsenijeviA8 V.	2018

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Genes for Stomatitis

Genes related to Stomatitis (0 elite genes):

(show all 27)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	LDLR	Low Density Lipoprotein Receptor	Protein Coding	33.16	GeneCards inferred via : Publications Proteins Functions (show sections)
2	IFNA2	Interferon Alpha 2	Protein Coding	28.09	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	7599051
3	CSF2	Colony Stimulating Factor 2	Protein Coding	27.36	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	9806514 7595716 11895067 (more) 9232612 7916041 8622096 11789420 11545238 16775647 10503860 17236223
4	TP63	Tumor Protein P63	Protein Coding	25.39	GeneCards inferred via : Publications Gene name (show sections)
5	NUP98	Nucleoporin 98	Protein Coding	25.05	GeneCards inferred via : Publications Proteins (show sections)
6	ATG5	Autophagy Related 5	Protein Coding	24.9	GeneCards inferred via : Proteins Functions (show sections)
7	ATG12	Autophagy Related 12	Protein Coding	24.9	GeneCards inferred via : Proteins Functions (show sections)
8	VDI	Vesicular Stomatitis Virus Defective Interfering Particle Suppression	Genetic Locus	24.78	GeneCards inferred via : Publications Gene name Functions (show sections)
9	ADAR	Adenosine Deaminase, RNA Specific	Protein Coding	24.37	GeneCards inferred via : Publications Functions (show sections)
10	DDX58	DExD/H-Box Helicase 58	Protein Coding	24.37	GeneCards inferred via : Publications Functions (show sections)
11	BST2	Bone Marrow Stromal Cell Antigen 2	Protein Coding	24.37	GeneCards inferred via : Publications Functions (show sections)
12	IFITM3	Interferon Induced Transmembrane Protein 3	Protein Coding	24.37	GeneCards inferred via : Publications Functions (show sections)
13	HNRNPK	Heterogeneous Nuclear Ribonucleoprotein K	Protein Coding	24.15	GeneCards inferred via : Publications Functions (show sections)
14	RSAD2	Radical S-Adenosyl Methionine Domain Containing 2	Protein Coding	14.81	GeneCards inferred via : Publications Functions (show sections)
15	AHSA1	Activator Of HSP90 ATPase Activity 1	Protein Coding	14.58	GeneCards inferred via : Publications Proteins (show sections)
16	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	14.37	GeneCards inferred via : Publications Functions (show sections)
17	IFITM2	Interferon Induced Transmembrane Protein 2	Protein Coding	14.37	GeneCards inferred via : Publications Functions (show sections)
18	CSF3	Colony Stimulating Factor 3	Protein Coding	14.22	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	7543781 9827976 10435157 (more) 10578160 15550581 7524888 11789420
19	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	14.2	GeneCards inferred via : Publications Functions (show sections)
20	IFI35	Interferon Induced Protein 35	Protein Coding	14.15	GeneCards inferred via : Publications Functions (show sections)
21	EIF3I	Eukaryotic Translation Initiation Factor 3 Subunit I	Protein Coding	14.15	GeneCards inferred via : Publications Functions (show sections)
22	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	13.32	DISEASES inferred ¹⁵ GeneCards inferred via : Functions (show sections)
23	DPYD	Dihydropyrimidine Dehydrogenase	Protein Coding	12.69	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	10473079 15820075 12352929 (more) 9007910 17165084
24	FGF7	Fibroblast Growth Factor 7	Protein Coding	12.37	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	11258848 18708365 15327889 (more) 12182998 17059384 16225371 17090603 15843784 16634706 16788155 18560408
25	MEFV	MEFV, Pyrin Innate Immunity Regulator	Protein Coding	12.29	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
26	TYMS	Thymidylate Synthetase	Protein Coding	12.05	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	16501586 17520255 15539918
27	IFNA1	Interferon Alpha 1	Protein Coding	12.02	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Stomatitis

Sources

Expression for Stomatitis

Search GEO for disease gene expression data for Stomatitis.

Sources

Pathways for Stomatitis

Pathways related to Stomatitis according to GeneCards Suite gene sharing:

(show all 11)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.79	ADAR ATG12 ATG5 BST2 CSF2 CSF3
2	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.08	ADAR BST2 CSF2 CSF3 DDX58 EIF2AK2
3	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.6	ADAR DDX58 EIF2AK2 HNRNPK IFNA2 NUP98
4	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways ⁶⁶ Show member pathways Cytosolic DNA-sensing pathway ³⁷ Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway ²² Negative regulators of RIG-I/MDA5 signaling ⁶⁶ NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 ⁶⁶ RIG-I-like Receptor Signaling ¹ RIG-I-like receptor signaling pathway ³⁷ TRAF3-dependent IRF activation pathway ⁶⁶ TRAF6 mediated IRF7 activation ⁶⁶ Virus Detection and Induction of Antiviral Signaling Pathways by RIG-I-like Receptors (RLR) ⁶⁵	12.55	ADAR ATG12 ATG5 DDX58 IFNA2 UBA52
5	Kaposi's sarcoma-associated herpesvirus infection ³⁷ Show member pathways Hepatitis B ³⁷	12.31	CSF2 DDX58 EIF2AK2 IFNA2
6	Regulation of IFNA signaling ⁶⁶ Show member pathways Cytokine Network ⁶⁴ Immune response IFN alpha/beta signaling pathway ²² Interferon alpha/beta signaling ⁶⁶ Interleukin-19, 20, 22, 24 ⁶⁶ Jak/STAT Signaling Pathway ⁶⁵ Jak-STAT signaling pathway ³⁷	12.2	ADAR BST2 CSF2 CSF3 IFI35 IFITM2
7	Hepatitis C ³⁷	11.85	DDX58 EIF2AK2 IFNA2 LDLR
8	Interferon gamma signaling ⁶⁶ Show member pathways Interferon Signaling ⁶⁶ Regulation of IFNG signaling ⁶⁶	11.85	ADAR BST2 DDX58 EIF2AK2 IFI35 IFITM2
9	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.72	CSF2 CSF3 IFNA2
10	Pink/Parkin Mediated Mitophagy ⁶⁶ Show member pathways Mitophagy ⁶⁶	11.3	ATG12 ATG5 UBA52
11	Peginterferon alpha-2a/Peginterferon alpha-2b Pathway (Hepatocyte), Pharmacodynamics ⁶¹ Show member pathways Inhibition of PKR ⁶⁶	10.92	ADAR DDX58 EIF2AK2 IFNA2

Sources

GO Terms for Stomatitis

Cellular components related to Stomatitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	phagophore assembly site membrane	GO:0034045	8.96	ATG12 ATG5
2	Atg12-Atg5-Atg16 complex	GO:0034274	8.62	ATG12 ATG5

Biological processes related to Stomatitis according to GeneCards Suite gene sharing:

(show all 19)

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of apoptotic process	GO:0043066	9.97	ADAR ATG5 EIF2AK2 HNRNPK TP63 UBA52
2	viral process	GO:0016032	9.93	DDX58 EIF2AK2 HNRNPK LDLR NUP98 RSAD2
3	immune system process	GO:0002376	9.92	ADAR ATG5 DDX58 EIF2AK2 RSAD2
4	cytokine-mediated signaling pathway	GO:0019221	9.88	CSF2 CSF3 IFNA2 UBA52
5	response to virus	GO:0009615	9.87	ADAR BST2 DDX58 EIF2AK2 IFITM2 IFITM3
6	defense response to virus	GO:0051607	9.86	ADAR BST2 DDX58 EIF2AK2 IFITM2 IFITM3
7	macroautophagy	GO:0016236	9.72	ATG12 ATG5 UBA52
8	response to interferon-gamma	GO:0034341	9.65	BST2 IFITM2 IFITM3
9	negative regulation of viral genome replication	GO:0045071	9.63	ADAR BST2 EIF2AK2 IFITM2 IFITM3 RSAD2
10	negative regulation of viral entry into host cell	GO:0046597	9.61	IFITM2 IFITM3 IFNA2
11	response to interferon-beta	GO:0035456	9.58	BST2 IFITM2 IFITM3
12	autophagy of nucleus	GO:0044804	9.57	ATG12 ATG5
13	obsolete positive regulation of transcription factor import into nucleus	GO:0042993	9.56	CSF3 DDX58
14	response to biotic stimulus	GO:0009607	9.54	IFITM2 IFITM3
15	neutrophil differentiation	GO:0030223	9.51	CSF2 CSF3
16	response to interferon-alpha	GO:0035455	9.35	ADAR BST2 EIF2AK2 IFITM2 IFITM3
17	type I interferon signaling pathway	GO:0060337	9.17	ADAR BST2 IFI35 IFITM2 IFITM3 IFNA2
18	positive regulation of transcription by RNA polymerase II	GO:0045944	10.06	CSF3 DDX58 HNRNPK NUP98 TP63 UBA52
19	innate immune response	GO:0045087	10.02	ADAR BST2 DDX58 EIF2AK2 IFITM2 IFITM3

Molecular functions related to Stomatitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein binding	GO:0005515	9.89	ADAR AHSA1 ATG12 ATG5 BST2 CSF2
2	identical protein binding	GO:0042802	9.63	BST2 DDX58 EIF2AK2 HNRNPK LDLR TP63
3	Atg8 ligase activity	GO:0019776	8.62	ATG12 ATG5

Sources

Sources for Stomatitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Stomatitis

Aliases & Classifications for Stomatitis

MalaCards integrated aliases for Stomatitis:

Classifications:

External Ids:

Summaries for Stomatitis

Related Diseases for Stomatitis

Diseases related to Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Stomatitis:

Symptoms & Phenotypes for Stomatitis

UMLS symptoms related to Stomatitis:

MGI Mouse Phenotypes related to Stomatitis:

Drugs & Therapeutics for Stomatitis

Drugs for Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 73 / NDF-RT 51 :

Cochrane evidence based reviews: stomatitis

Genetic Tests for Stomatitis

Anatomical Context for Stomatitis

MalaCards organs/tissues related to Stomatitis:

Publications for Stomatitis

Articles related to Stomatitis:

Genes for Stomatitis

Genes related to Stomatitis (0 elite genes):

Variations for Stomatitis

Expression for Stomatitis

Pathways for Stomatitis

Pathways related to Stomatitis according to GeneCards Suite gene sharing:

GO Terms for Stomatitis

Cellular components related to Stomatitis according to GeneCards Suite gene sharing:

Biological processes related to Stomatitis according to GeneCards Suite gene sharing:

Molecular functions related to Stomatitis according to GeneCards Suite gene sharing:

Sources for Stomatitis

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :