Aliases & Classifications for Stomatitis

MalaCards integrated aliases for Stomatitis:

Name: Stomatitis 12 74 54 44 15 17 71


External Ids:

Disease Ontology 12 DOID:9637
MeSH 44 D013280
NCIt 50 C26887
SNOMED-CT 67 95361005
ICD10 32 K12.1
UMLS 71 C0038362

Summaries for Stomatitis

Disease Ontology : 12 A mouth disease that is characterized by inflammation of the mouth and lips.

MalaCards based summary : Stomatitis is related to aphthous stomatitis and pharyngitis, and has symptoms including oral mucosal blisters, enanthema and oral manifestations. An important gene associated with Stomatitis is VDI (Vesicular Stomatitis Virus Defective Interfering Particle Suppression), and among its related pathways/superpathways are Innate Immune System and Toll-like Receptor Signaling Pathway. The drugs Ethanol and Pemetrexed have been mentioned in the context of this disorder. Affiliated tissues include breast, t cells and bone marrow, and related phenotypes are hematopoietic system and immune system

Wikipedia : 74 Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

Related Diseases for Stomatitis

Diseases related to Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 728)
# Related Disease Score Top Affiliating Genes
1 aphthous stomatitis 33.0 TNF IL6 IL1B CSF2
2 pharyngitis 31.6 TNF IL6 IL1B CSF2
3 glossitis 31.4 TNF IL6 IL1B
4 lichen planus 31.3 TNF IL6 IL1B
5 newcastle disease 31.2 TNF EIF2AK2 DDX58
6 mouth disease 31.2 IL6 DDX58 ATG5 ATG12
7 vaccinia 31.2 TNF IL6 EIF2AK2 CSF2
8 candidiasis 31.1 TNF IL6 IL1B CSF2
9 gingivitis 31.1 TNF IL6 IL1B CSF3
10 familial mediterranean fever 31.1 TNF IL6 IL1B
11 tonsillitis 31.0 TNF IL6 IL1B
12 encephalitis 31.0 TNF RSAD2 IL6 IL1B DDX58
13 severe acute respiratory syndrome 31.0 TNF IL6 IL1B DDX58
14 esophagitis 31.0 TNF IL6 IL1B
15 measles 30.9 TNF IL6 IL1B EIF2AK2 DDX58 ADAR
16 mucositis 30.9 IL1B CSF3 CSF2
17 lymphocytic choriomeningitis 30.9 IL6 DDX58 ADAR
18 avian influenza 30.8 TNF IL6 DDX58
19 plague 30.7 TNF IL6 IL1B DDX58
20 burning mouth syndrome 30.7 TNF IL6 IL1B
21 dermatitis 30.7 TNF IL6 IL1B CSF2
22 viral encephalitis 30.7 TNF IL6 IL1B
23 urethritis 30.7 TNF IL6 IL1B
24 immune deficiency disease 30.6 TNF IL6 IL1B EIF2AK2 CSF2 BST2
25 mumps 30.6 TNF IL6 IL1B EIF2AK2
26 hepatitis c virus 30.6 RSAD2 LDLR EIF2AK2 DDX58 ATG5
27 uveitis 30.6 TNF IL6 IL1B IFNA2
28 crohn's disease 30.5 TNF IL6 IL1B CSF2
29 exanthem 30.5 TNF IL6 IL1B CSF3 CSF2
30 crimean-congo hemorrhagic fever 30.5 TNF IL6 DDX58
31 graft-versus-host disease 30.5 TNF IL6 IL1B
32 herpangina 30.5 TNF IL6 IL1B DDX58
33 chikungunya 30.5 TNF RSAD2 IL6 IL1B DDX58 BST2
34 yellow fever 30.4 RSAD2 IL6 IL1B DDX58
35 laryngitis 30.4 TNF IL6 IL1B
36 influenza 30.4 TNF RSAD2 NUP98 IL6 IL1B IFITM3
37 cervicitis 30.4 TNF IL6 IL1B
38 atrophic gastritis 30.4 TNF IL6 IL1B
39 hantavirus hemorrhagic fever with renal syndrome 30.4 TNF IL6 DDX58
40 periodic fever, familial, autosomal dominant 30.4 TNF IL6 IL1B
41 spondylitis 30.3 TNF IL6 IL1B
42 duodenal ulcer 30.3 TNF IL6 IL1B
43 erythema nodosum 30.3 TNF IL6 IL1B CSF2
44 behcet syndrome 30.3 TNF IL6 IL1B IFNA2 CSF2
45 west nile virus 30.2 RSAD2 IFITM3 IFITM2 DDX58
46 osteomyelitis 30.2 TNF IL6 IL1B CSF3
47 cyclic neutropenia 30.2 TNF IL1B CSF3 CSF2
48 toxoplasmosis 30.2 TNF IL6 IL1B
49 periodontitis, chronic 30.2 IL6 IL1B
50 bacterial infectious disease 30.2 TNF IL6 IL1B CSF3 CSF2

Graphical network of the top 20 diseases related to Stomatitis:

Diseases related to Stomatitis

Symptoms & Phenotypes for Stomatitis

UMLS symptoms related to Stomatitis:

oral mucosal blisters, enanthema, oral manifestations, burning mucosal, oral pain, sore roof of mouth (symptom)

MGI Mouse Phenotypes related to Stomatitis:

# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.93 ADAR ATG5 CSF2 CSF3 DDX58 EIF2AK2
2 immune system MP:0005387 9.8 ADAR ATG5 CSF2 CSF3 DDX58 EIF2AK2
3 neoplasm MP:0002006 9.17 CSF2 DDX58 EIF2AK2 IL1B IL6 TNF

Drugs & Therapeutics for Stomatitis

Drugs for Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 305)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Ethanol Approved Phase 4 64-17-5 702
Pemetrexed Approved, Investigational Phase 4 150399-23-8, 137281-23-3 446556 60843
Levoleucovorin Approved, Investigational Phase 4 68538-85-2 149436
Racepinephrine Approved Phase 4 329-65-7 838
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
Sodium citrate Approved, Investigational Phase 4 68-04-2
Hexetidine Approved, Investigational Phase 4 141-94-6
Ofloxacin Approved Phase 4 82419-36-1 4583
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
Morphine Approved, Investigational Phase 4 57-27-2 5288826
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
tannic acid Approved Phase 4 1401-55-4
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
Amifostine Approved, Investigational Phase 4 20537-88-6 2141
Diphenhydramine Approved, Investigational Phase 4 147-24-0, 58-73-1 3100
Promethazine Approved, Investigational Phase 4 60-87-7 4927
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
Povidone Approved Phase 4 9003-39-8 131751496
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
Simethicone Approved Phase 4 8050-81-5
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
Castor oil Approved, Investigational, Nutraceutical, Vet_approved Phase 4 8001-79-4
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
28 Anti-Infective Agents, Local Phase 4
29 Ionophores Phase 4
30 Vitamin B Complex Phase 4
31 Folate Phase 4
32 Vitamin B9 Phase 4
33 Folic Acid Antagonists Phase 4
Bilirubin Phase 4 635-65-4 5280352
35 N-Methylaspartate Phase 4
36 Disinfectants Phase 4
37 Epinephryl borate Phase 4
38 Eusol Phase 4
39 Castor Phase 4
40 Sodium hypochlorite Phase 4
41 Citrate Phase 4
42 Ether Phase 4
43 Anti-Infective Agents Phase 4
44 Anti-Bacterial Agents Phase 4
45 Cytochrome P-450 Enzyme Inhibitors Phase 4
46 Anesthetics Phase 4
47 Analgesics Phase 4
48 Narcotics Phase 4
49 Analgesics, Opioid Phase 4
50 Anesthetics, General Phase 4

Interventional clinical trials:

(show top 50) (show all 254)
# Name Status NCT ID Phase Drugs
1 Efficacy of Two Different Oral Hygiene Regimens on the Incidence and Severity of Oral Mucositis in Patients Receiving Hematopoietic Stem Cell Transplantation - A Randomized Controlled Trial Unknown status NCT02662374 Phase 4 .02% Chlorohexidine Gluconate;3% Sodium Bicarbonate;Nystatin 10000U/ml;Supersaturated Calcium Phosphate
2 Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer Unknown status NCT01876407 Phase 4
3 A Randomized Study on the Effects of Lactobacillus Brevis CD2 in the Prevention of Radio and Chemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients. Unknown status NCT01707641 Phase 4
4 Open-Label Single-Arm Phase IV Study of Pemetrexed in Taiwanese Patients With Advanced Non-Small Cell Lung Cancer Who Have Had Prior Chemotherapy Completed NCT00380718 Phase 4 pemetrexed
5 Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers: a Randomized Clinical Trial Completed NCT02642900 Phase 4 Nystatin 100.000 units
6 Clinical Evaluation of an Experimental Solution Based on Ricinus Communis Compared to Sodium Hypochlorite for Denture Cleansing Completed NCT02407834 Phase 4
7 Local Administration of Morphine: An Evaluation of the Analgesic Effect at Stomatitis in Children Completed NCT00357942 Phase 4 morphine solution for injection;Placebo;morphine mouthwash;Placebo
8 A Randomized, Double-blind Study to Evaluate the Efficacy of MuGard Mucoadhesive Oral Wound Rinse for the Amelioration of Oral Mucositis in Subjects Receiving Chemoradiation Therapy for the Treatment of Cancers of the Head and Neck Completed NCT01283906 Phase 4
9 Evaluation of the Efficacy of a Hexetidine- and Chlorobutanol-based Mouthwash in the Symptomatic Treatment of Oral Lesions Due to Removable Prostheses: a Prospective, Randomized, Triple-blind Controlled Clinical Trial Completed NCT01115049 Phase 4 chlorobutanol, hexetidine;Chlorhexidine
10 Clinical Study of the Effects of Compound Kushen Injection on Radiation-induced Oral Mucositis in Head and Neck Cancer Patients. Recruiting NCT04204382 Phase 4 Levofloxacin injection;Compound kushen injection
11 A Comparison of Oral Controlled-release Morphine With Transdermal Fentanyl in Nasopharyngeal Cancer Patients With Moderate or Severe Oral Mucositis Pain Induced by Chemoradiotherapy Not yet recruiting NCT04292990 Phase 4 Fentanyl;Morphine
12 Prospective, Open-label, Randomized, Control Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine Suspended NCT01288625 Phase 4 Amifostine
13 An Adaptive Design, Single-Blind, Randomized, Controlled Study Investigating Polyvinylpyrrolidone (PVP) and Sodium Hyaluronate-Containing Oral Gel (Gelclair®) in Comparison to Viscous Lidocaine, Diphenhydramine, and Aluminum-magnesium Hydroxide/Simethicone Antacid Suspension Mouthwash ("Magic Mouthwash") for the Management of Oral Mucositis Associated With High Dose Chemotherapy and Methotrexate in Allogeneic Stem Cell Transplant Recipients Terminated NCT03490396 Phase 4
14 The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients Unknown status NCT01099891 Phase 3 rhEGF;Placebo
15 A Pilot Study on the Efficacy of Lactobacillus Brevis CD2 Lozenges in Preventing Oral Mucositis by High-dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation Unknown status NCT02085694 Phase 2, Phase 3 Lactobacillus brevis CD2
16 Laser Therapy Prevents Mucositis Oral in Patients Undergoing to Chemotherapy for Bone Marrow Transplantation? A Randomized Clinical Trial. Unknown status NCT02020928 Phase 3
17 A Multinational, Multicenter, Double-Blind, Placebo-Controlled, Randomized, Phase III Clinical Trial to Determine the Efficacy and Safety of IB-367 Rinse in Reducing the Severity of Oral Mucositis in Patients Receiving Radiotherapy for Head and Neck Malignancy Unknown status NCT00022373 Phase 3 iseganan HCl oral solution
18 Evaluation of Low-energy Laser Therapy for Prevention and Reduction of Severity of Oral Mucositis in Children "Mucositis Laser 1" Unknown status NCT01007617 Phase 2, Phase 3
19 Phase III Randomized Double-blind Cross-over Trial of Caphosol® Versus NaCl 0.9% in the Relief of Oral Mucositis in Renal Cell Carcinoma, Hepatocellular Carcinoma, and Gastrointestinal Stromal Tumor Patients Receiving Targeted Therapy Completed NCT01265810 Phase 3
20 A Double-Blind, Randomized, Vehicle-Controlled Study Comparing the Safety and Efficacy of Benzydamine HCl 0.15% Oral Rinse Including a Separate Open-Label Standard of Care Arm in Subjects With Radiation-Induced Mucositis Completed NCT00051441 Phase 3 Benzydamine Hydrochloride 0.15% Oral Rinse
21 Laser Therapy Associated With Photodynamic Therapy in the Treatment of Oral Mucositis Induced by Chemotherapy in Young Patients: Randomized Blind Clinical Trial Completed NCT02555501 Phase 3
22 Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic in Elderly People Completed NCT02818803 Phase 3 Miconazole
23 Prevention of Recurrent Aphthous Stomatitis Using Vitamins Completed NCT00527306 Phase 3
24 Effectiveness of Topical Hyaluronic Acid Versus Chlorhexidine Mouthwashes in the Treatment of Recurrent Aphthous Stomatitis: A Randomized Clinical Trial Completed NCT04265001 Phase 3 Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
25 A Phase 3, Randomized, Double-blind, Placebo-controlled Trial of Recombinant Human Keratinocyte Growth Factor for Reduction of Mucositis in Patients With Hematologic Malignancies Undergoing Total Body Irradiation and High-dose Chemotherapy With Autologous PBPC Transplantation Completed NCT00041665 Phase 3 Recombinant Human Keratinocyte Growth Factor
26 Evaluating the Effectiveness of Topical Morphine Compared With a Routine Mouthwash in Managing Cancer Treatment-induced Mucositis in Patients With Head and Neck Cancer in Isfahan Completed NCT01837446 Phase 2, Phase 3 2% morphine solution;Magnesium aluminum hydroxide;2% viscous lidocaine;Diphenhydramine
27 LAMPO: Multicenter Randomized Double-blind Controlled Trial to Evaluate the Efficacy of Laser Therapy for Treatment of Oral Mucositis Induced by Chemotherapy in Children Completed NCT02762019 Phase 3
28 A Randomized,Controlled Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis. Completed NCT02303197 Phase 3 ChiNing decoction
29 Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation : a Randomized Double Blind Multicenter Prospective Phase III Trial Completed NCT02696408 Phase 3
30 A Double-Blind, Randomized, Placebo-controlled Study of Two Different Schedules of Palifermin for Reduction in Severity of Oral Mucositis in Subjects With Multiple Myeloma Receiving Melphalan Followed by Autologous Blood Stem Cell Transplantation Completed NCT00434161 Phase 3 Palifermin before only;Placebo;Palifermin before and after
31 A Comparison of Acute Oral Mucositis Between Morning and Afternoon Radiotherapy in Patients Receiving Radiation Treatment for Cancer of the Head and Neck Completed NCT00004234 Phase 3
32 Phase III Trial of Low-level Laser Therapy to Prevent Induced Oral Mucositis in Head and Neck Cancer Patients Submitted to Concurrent Chemoradiation Completed NCT01439724 Phase 3
33 A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer Completed NCT00615420 Phase 3
34 A Randomized Double-Blind Study of Doxepin Rinse Versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy Completed NCT01156142 Phase 3 doxepin hydrochloride
35 A Phase II/III Blinded Randomized Trial to Determine the Efficacy of Low Energy Diode Laser Therapy (650 nm or 780 nm) to Prevent Oral Mucositis Following Bone Marrow Transplantation Completed NCT00024037 Phase 2, Phase 3
36 Khon Kaen University Ethics Committee in Human Research Completed NCT02536781 Phase 2, Phase 3 Anthocyanin;Placebo
37 Effect of Ascorbic Acid Oral Supplementation in Assessing the Severity of Oral Mucositis in Chemo-radiation Therapy of Head and Neck Cancers. Completed NCT02868151 Phase 2, Phase 3 Ascorbic Acid;Zinc acetate
38 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Adjuvant Radiotherapy and Chemotherapy(RT/CT) Completed NCT00131638 Phase 3 Placebo;Palifermin
39 A Randomized, Blinded, Active-control Trial of Palifermin (rHuKGF) to Evaluate Oral Mucositis in Subjects With Hematologic Malignancies Undergoing Fractionated Total Body Irradiation (fTBI) and High Dose Chemotherapy With Autologous Peripheral Blood Progenitor Cell (PBPC) Transplantation Completed NCT00109031 Phase 3 palifermin;Cyclophosphamide;Etoposide;Placebo
40 A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse
41 A Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Palifermin (Recombinant Human Keratinocyte Growth Factor) for Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer Receiving 5-FU and Leucovorin as Adjuvant Therapy Completed NCT00393822 Phase 2, Phase 3 palifermin;placebo
42 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Radiotherapy With Concurrent Chemotherapy (RT/CT) Completed NCT00101582 Phase 3 Placebo;palifermin;cisplatin chemotherapy
43 A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2 Completed NCT00001812 Phase 3 Nystatin
44 Evaluate Safety and Tolerability and Compare Absorption/Distribution Kinetics of a Single 100 Mcg Dose of Fentanyl Sublingual Spray (Fentanyl SL Spray) in Cancer Subjects With or Without Oral Mucositis Completed NCT00956254 Phase 3 Fentanyl sublingual spray
45 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase III Clinical Study to Assess the Efficacy and Safety of SBG on Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT00790322 Phase 3 SBG
46 Randomized Cross-over Study of Curcumin for Prevention of Oral Mucositis in Children Receiving Doxorubicin Based Chemotherapy. Completed NCT00475683 Phase 3
47 Clinical Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis as Adjunctive Therapy in Non-surgical Treatment of Periimplant Mucositis: a Randomized Controlled Trial Completed NCT04187222 Phase 3
48 Evaluation of Oral Care to Prevent Oral Mucositis in Estrogen Receptor Positive Metastatic Breast Cancer Patients Treated With Everolimus: Phase III Randomized Control Trial Completed NCT02376985 Phase 3 Everolimus
49 A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy Completed NCT02229539 Phase 3 doxepin hydrochloride oral solution;DLA (diphenhydramine, lidocaine and antacids) rinse
50 A Phase 2b/3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Clonidine Mucoadhesive Buccal Tablet to Placebo to Prevent Chemoradiotherapy-induced Severe Oral Mucositis in Patients With Oropharyngeal Cancer Recruiting NCT04648020 Phase 2, Phase 3 Clonidine HCl Mucoadhesive Buccal Tablet;Placebo Mucoadhesive Buccal Tablet

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS 71 / NDF-RT 51 :

carbamide peroxide

Cochrane evidence based reviews: stomatitis

Genetic Tests for Stomatitis

Anatomical Context for Stomatitis

MalaCards organs/tissues related to Stomatitis:

Breast, T Cells, Bone Marrow, Myeloid, Skin, Prostate, Colon

Publications for Stomatitis

Articles related to Stomatitis:

(show top 50) (show all 14807)
# Title Authors PMID Year
A phase I and pharmacokinetic study of OSI-7904L, a liposomal thymidylate synthase inhibitor in combination with oxaliplatin in patients with advanced colorectal cancer. 61 54
17520255 2008
DPYD*2A mutation: the most common mutation associated with DPD deficiency. 54 61
17165084 2007
Phase II trial of pralatrexate (10-propargyl-10-deazaaminopterin, PDX) in patients with unresectable malignant pleural mesothelioma. 61 54
17409804 2007
First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. 54 61
15550581 2004
Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy. 54 61
15539918 2004
Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients. 54 61
12352929 2002
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. 54 61
10473079 1999
Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy. 61 54
9007910 1997
High dose busulphan/cyclophosphamide for autologous bone marrow transplantation is associated with minimal non-hemopoietic toxicity. 61 54
7524888 1994
Everolimus after failure of one prior VEGF-targeted therapy in metastatic renal cell carcinoma: Final results of the MARC-2 trial. 61
33070307 2021
Suitability of two rapid lateral flow immunochromatographic assays for predicting SARS-CoV-2 neutralizing activity of sera. 61
33236799 2021
Lassa-VSV chimeric virus targets and destroys human and mouse ovarian cancer by direct oncolytic action and by initiating an anti-tumor response. 61
33453650 2021
Colchicine in the treatment of refractory aphthous ulcerations: Review of the literature and two case reports. 61
33603888 2021
Expression of porcine interferon-α and its bioactivity analysis in vitro and in vivo. 61
33051705 2021
A phase I trial of temsirolimus and erlotinib in patients with refractory solid tumors. 61
33159216 2021
Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells. 61
33558862 2021
Comprehensive and systemic optimization for improving the yield of SARS-CoV-2 spike pseudotyped virus. 61
33521163 2021
Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection. 61
32441445 2021
Metal-Protein Nanoparticles Facilitate Anti-VSV and H1N1 Viruses Through the Coordinative Actions on Innate Immune Responses and METTL14. 61
33522144 2021
Efficacy and toxicity of pegylated liposomal doxorubicin as therapy for recurrent ovarian cancer in relation to the number of previous chemotherapy regimens: Comparison with gemcitabine. 61
33145906 2021
Association between serum zinc levels and recurrent aphthous stomatitis: a meta-analysis with trial sequential analysis. 61
33409687 2021
Children and Adults with PFAPA Syndrome: Similarities and Divergences in a Real-Life Clinical Setting. 61
33315168 2021
Oral manifestations of COVID-19: Brief review. 61
33590976 2021
The comparison of FOLFOX regimens with different doses of 5-FU for the adjuvant treatment of colorectal cancer: a multicenter study. 61
33586012 2021
Everolimus in adult tuberous sclerosis complex patients with epilepsy: Too late for success? A retrospective study. 61
33534134 2021
Stomatitis associated with osimertinib in advanced lung cancer treatment: Characterization and implications for management. 61
33353757 2021
Oral manifestations of celiac disease in French children. 61
33341334 2021
No Evidence of rVSV-Ebola Virus Vaccine Replication or Dissemination in the Sand Fly Phlebotomus papatasi. 61
33534737 2021
Aphthous stomatitis in a man with psoriatic arthritis. 61
33607089 2021
Anti-poliovirus activity of Nerium oleander aqueous extract. 61
30908090 2021
Long-term response to afatinib in an elderly patient with uncommon epidermal growth factor receptor mutation-positive lung adenocarcinoma. 61
33533191 2021
Vibrational Spectroscopic Detection of a Single Virus by Mid-Infrared Photothermal Microscopy. 61
33596049 2021
The antimicrobial and antibiofilm properties of allicin against Candida albicans and Staphylococcus aureus - A therapeutic potential for denture stomatitis. 61
33551624 2021
Safety and Quality-of-Life Data from an Italian Expanded Access Program of Lenvatinib for Treatment of Thyroid Cancer. 61
32907501 2021
Tupaia guanylate-binding protein 1 interacts with vesicular stomatitis virus phosphoprotein and represses primary transcription of the viral genome. 61
33271385 2021
Inhibition of glioma using a novel non-neurotoxic vesicular stomatitis virus. 61
33524950 2021
Near-Complete Genome Sequences of Vesicular Stomatitis Virus Isolates from the 2020 Outbreak in Kansas. 61
33602738 2021
Recent advances in the aetiology of recurrent aphthous stomatitis (RAS). 61
33574180 2021
Lifetime prevalence of recurrent aphthous stomatitis and its related factors in Northern Iranian population: The PERSIAN Guilan Cohort Study. 61
33030579 2021
Benefits of the Involvement of Dentists in Managing Oral Complications Among Patients With Oral Cavity and Oropharyngeal Cancer: An Analysis of Claims Data. 61
33555929 2021
Quantifying Absolute Neutralization Titers against SARS-CoV-2 by a Standardized Virus Neutralization Assay Allows for Cross-Cohort Comparisons of COVID-19 Sera. 61
33593976 2021
Effectiveness of denture microwave disinfection for treatment of denture stomatitis: A systematic review and meta-analysis. 61
33022878 2021
Physicomechanical, optical, and antifungal properties of polymethyl methacrylate modified with metal methacrylate monomers. 61
33581867 2021
A phase 1b trial of prexasertib in combination with chemoradiation in patients with locally advanced head and neck squamous cell carcinoma. 61
33577866 2021
Computational and Experimental Studies Reveal That Thymoquinone Blocks the Entry of Coronaviruses Into In Vitro Cells. 61
33532909 2021
Oral Paracoccidioidomycosis affecting women: A systematic review. 61
33031605 2021
Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment. 61
33593882 2021
Phytochemicals and biological properties of Annona coriacea Mart. (Annonaceae): A systematic review from 1971 to 2020. 61
33484716 2021
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants. 61
33567448 2021
In silico trials predict that combination strategies for enhancing vesicular stomatitis oncolytic virus are determined by tumor aggressivity. 61
33608375 2021

Variations for Stomatitis

Expression for Stomatitis

Search GEO for disease gene expression data for Stomatitis.

Pathways for Stomatitis

Pathways related to Stomatitis according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
Show member pathways
Show member pathways
Show member pathways
Show member pathways
Show member pathways
Show member pathways
Show member pathways
Show member pathways
12.55 TNF IFNA2 DDX58 ATG5 ATG12
10 12.39 TNF IL1B CSF2 ATG5 ATG12
Show member pathways
12.38 IL6 IFNA2 CSF3 CSF2
Show member pathways
12.32 TNF IL6 IL1B CSF3 CSF2
Show member pathways
14 12.23 TNF IL6 IL1B IFNA2
15 12.23 TNF IL6 IL1B IFNA2 ATG5 ATG12
Show member pathways
Show member pathways
Show member pathways
19 11.99 TNF IL6 IFNA2 CSF3 CSF2
20 11.97 TNF IL6 IL1B CSF2
21 11.94 IL6 IL1B ATG5 ATG12
22 11.92 TNF IL6 IL1B CSF2
23 11.9 TNF IL6 IL1B CSF3 CSF2
24 11.87 TNF IL6 IL1B CSF2
Show member pathways
11.74 TNF IL6 IL1B
26 11.74 TNF IL6 IL1B
27 11.72 TNF IL6 IL1B IFNA2 CSF2
Show member pathways
11.68 TNF IL6 IL1B CSF2
29 11.63 TNF IL6 IL1B CSF3 CSF2
30 11.6 TNF IL6 IL1B
31 11.57 TNF IL6 IL1B CSF3
32 11.53 IL6 IL1B CSF3 CSF2
33 11.49 TNF IL6 IL1B
34 11.49 TNF IL6 IL1B CSF3 CSF2
35 11.39 IL1B IFNA2 EIF2AK2
36 11.39 TNF IL6 IL1B
37 11.36 TNF IL6 IL1B
38 11.31 TNF IL6 IL1B
39 11.3 TNF IL6 IL1B
Show member pathways
41 11.12 TNF IL6 IL1B CSF3 CSF2
42 10.77 IL6 IL1B

GO Terms for Stomatitis

Cellular components related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Atg12-Atg5-Atg16 complex GO:0034274 8.62 ATG5 ATG12

Biological processes related to Stomatitis according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 10.13 TP63 TNF NUP98 IL6 IL1B IFNA2
2 immune system process GO:0002376 10.11 RSAD2 IFITM3 IFITM2 EIF2AK2 DDX58 BST2
3 innate immune response GO:0045087 10.1 RSAD2 IFITM3 IFITM2 EIF2AK2 DDX58 BST2
4 positive regulation of gene expression GO:0010628 10.09 TNF LDLR IL6 IL1B DDX58 CSF2
5 immune response GO:0006955 10 TNF IL6 IL1B IFITM3 IFITM2 CSF3
6 cytokine-mediated signaling pathway GO:0019221 9.97 TNF IL6 IL1B IFNA2 CSF3 CSF2
7 viral process GO:0016032 9.97 RSAD2 NUP98 LDLR EIF2AK2 DDX58 ATG5
8 cellular response to lipopolysaccharide GO:0071222 9.95 TNF IL6 IL1B CSF3 CSF2
9 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.94 TNF IL6 IL1B EIF2AK2
10 positive regulation of interleukin-6 production GO:0032755 9.89 TNF IL6 IL1B DDX58
11 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.87 TNF IL6 IFNA2 CSF2
12 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.86 TNF IL6 CSF3
13 regulation of insulin secretion GO:0050796 9.85 TNF IL6 IL1B
14 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.84 TNF IL1B EIF2AK2
15 positive regulation of interleukin-8 production GO:0032757 9.84 TNF IL6 IL1B DDX58
16 humoral immune response GO:0006959 9.83 TNF IL6 IFNA2
17 positive regulation of DNA-binding transcription factor activity GO:0051091 9.83 TNF IL6 IL1B DDX58 CSF3
18 positive regulation of chemokine production GO:0032722 9.8 TNF IL6 EIF2AK2
19 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.8 TNF IL1B CSF2
20 type I interferon signaling pathway GO:0060337 9.8 RSAD2 IFNA2 IFITM3 IFITM2 BST2 ADAR
21 negative regulation of neurogenesis GO:0050768 9.78 TNF IL6 IL1B
22 response to interferon-gamma GO:0034341 9.77 IFITM3 IFITM2 BST2
23 negative regulation of viral entry into host cell GO:0046597 9.76 IFNA2 IFITM3 IFITM2
24 positive regulation of glial cell proliferation GO:0060252 9.75 TNF IL6 IL1B
25 negative regulation of viral genome replication GO:0045071 9.73 TNF RSAD2 IFITM3 IFITM2 EIF2AK2 BST2
26 positive regulation of neuroinflammatory response GO:0150078 9.7 TNF IL6 IL1B
27 positive regulation of granulocyte macrophage colony-stimulating factor production GO:0032725 9.68 IL1B DDX58
28 positive regulation of podosome assembly GO:0071803 9.68 TNF CSF2
29 regulation of establishment of endothelial barrier GO:1903140 9.68 TNF IL1B
30 negative regulation of lipid storage GO:0010888 9.67 TNF IL6
31 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.66 RSAD2 IL6
32 autophagy of nucleus GO:0044804 9.66 ATG5 ATG12
33 positive regulation of fever generation GO:0031622 9.65 TNF IL1B
34 response to interferon-beta GO:0035456 9.65 IFITM3 IFITM2 BST2
35 sequestering of triglyceride GO:0030730 9.64 TNF IL1B
36 C-terminal protein lipidation GO:0006501 9.63 ATG5 ATG12
37 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.62 TNF IL1B
38 defense response to virus GO:0051607 9.61 RSAD2 IL6 IFNA2 IFITM3 IFITM2 EIF2AK2
39 vascular endothelial growth factor production GO:0010573 9.58 TNF IL6 IL1B
40 response to interferon-alpha GO:0035455 9.55 IFITM3 IFITM2 EIF2AK2 BST2 ADAR
41 response to virus GO:0009615 9.23 TNF RSAD2 IFITM3 IFITM2 EIF2AK2 DDX58

Molecular functions related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 double-stranded RNA binding GO:0003725 9.13 EIF2AK2 DDX58 ADAR
2 cytokine activity GO:0005125 9.1 TNF IL6 IL1B IFNA2 CSF3 CSF2

Sources for Stomatitis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
70 Tocris
72 UMLS via Orphanet
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