Aliases & Classifications for Stomatitis

MalaCards integrated aliases for Stomatitis:

Name: Stomatitis 12 73 54 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:9637
MeSH 44 D013280
NCIt 50 C26887
SNOMED-CT 67 95361005
ICD10 32 K12.1
UMLS 70 C0038362

Summaries for Stomatitis

Disease Ontology : 12 A mouth disease that is characterized by inflammation of the mouth and lips.

MalaCards based summary : Stomatitis is related to aphthous stomatitis and pharyngitis, and has symptoms including oral mucosal blisters, enanthema and oral manifestations. An important gene associated with Stomatitis is VDI (Vesicular Stomatitis Virus Defective Interfering Particle Suppression), and among its related pathways/superpathways are Innate Immune System and Measles. The drugs Ethanol and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and myeloid, and related phenotypes are hematopoietic system and immune system

Wikipedia : 73 Stomatitis is inflammation of the mouth and lips. It refers to any inflammatory process affecting the... more...

Related Diseases for Stomatitis

Diseases related to Stomatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 567)
# Related Disease Score Top Affiliating Genes
1 aphthous stomatitis 32.9 TNF IL6 CSF2
2 pharyngitis 31.6 TNF IL6 CSF2
3 mouth disease 31.2 IL6 DDX58 ATG5 ATG12
4 measles 31.0 TNF IL6 DDX58 ADAR
5 encephalitis 31.0 TNF RSAD2 IL6 DDX58
6 gingivitis 31.0 TNF IL6 CSF3
7 lymphocytic choriomeningitis 30.8 IL6 DDX58 ADAR
8 severe acute respiratory syndrome 30.8 TNF IL6 DDX58
9 plague 30.7 TNF IL6 DDX58
10 avian influenza 30.7 TNF IL6 DDX58
11 hepatitis c virus 30.7 RSAD2 LDLR DDX58 ATG5
12 influenza 30.6 TNF RSAD2 NUP98 IL6 IFITM3 IFITM2
13 exanthem 30.5 TNF IL6 CSF3 CSF2
14 chikungunya 30.5 TNF RSAD2 IL6 DDX58 BST2
15 crimean-congo hemorrhagic fever 30.4 TNF IL6 DDX58
16 herpangina 30.4 TNF IL6 DDX58
17 yellow fever 30.4 RSAD2 IL6 DDX58
18 hantavirus hemorrhagic fever with renal syndrome 30.3 TNF IL6 DDX58
19 erythema nodosum 30.3 TNF IL6 CSF2
20 cyclic neutropenia 30.2 TNF CSF3 CSF2
21 west nile virus 30.2 RSAD2 IFITM3 IFITM2 DDX58
22 bacterial infectious disease 30.2 TNF IL6 CSF3 CSF2
23 behcet syndrome 30.2 TNF IL6 IFNA2 CSF2
24 hepatitis c 30.2 TNF RSAD2 IFNA2 DDX58
25 granulocytopenia 30.1 TNF CSF3 CSF2
26 osteomyelitis 30.1 TNF IL6 CSF3
27 diarrhea 30.1 TNF IL6 IFNA2 CSF3
28 dengue virus 30.1 TNF RSAD2 IFITM3 IFITM2 DDX58
29 gastroenteritis 30.0 TNF IL6 CSF3 CSF2
30 meningitis 30.0 TNF IL6 CSF3 CSF2
31 bronchiolitis 30.0 TNF IL6 CSF2
32 japanese encephalitis 30.0 TNF RSAD2 DDX58
33 rubella 30.0 TNF IL6 DDX58
34 viral infectious disease 30.0 TNF IL6 IFNA2 DDX58
35 hemorrhagic disease 29.9 TNF IL6 DDX58 CSF3
36 dysentery 29.9 TNF IL6 IFNA2
37 smallpox 29.9 TNF CSF3 CSF2
38 mucositis 29.9 FGF7 DPYD CSF3 CSF2
39 pyoderma 29.8 TNF IFNA2 CSF3
40 leprosy 3 29.8 TNF IL6 CSF2
41 aspergillosis 29.7 TNF IL6 CSF3 CSF2
42 chronic mucocutaneous candidiasis 29.7 TNF IL6 CSF3 CSF2
43 bacterial pneumonia 29.7 TNF IL6 CSF3
44 common cold 29.6 TNF IL6 IFNA2 CSF2
45 skin disease 29.6 TP63 TNF IL6 FGF7 DDX58 CSF2
46 acquired immunodeficiency syndrome 29.6 TNF IL6 IFNA2 CSF2
47 deficiency anemia 29.6 TNF IL6 IFNA2 CSF3 CSF2
48 pyoderma gangrenosum 29.6 TNF IFNA2 CSF3
49 cellulitis 29.5 TNF IL6 CSF3 CSF2
50 herpes zoster 29.5 TNF IFNA2 DPYD

Graphical network of the top 20 diseases related to Stomatitis:



Diseases related to Stomatitis

Symptoms & Phenotypes for Stomatitis

UMLS symptoms related to Stomatitis:


oral mucosal blisters; enanthema; oral manifestations; burning mucosal; oral pain; sore roof of mouth (symptom)

MGI Mouse Phenotypes related to Stomatitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.73 ADAR ATG5 CSF2 CSF3 DDX58 DPYD
2 immune system MP:0005387 9.47 ADAR ATG5 CSF2 CSF3 DDX58 DPYD

Drugs & Therapeutics for Stomatitis

Drugs for Stomatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 313)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4 64-17-5 702
2
Levoleucovorin Approved, Investigational Phase 4 68538-85-2 149436
3
Pemetrexed Approved, Investigational Phase 4 150399-23-8, 137281-23-3 60843 446556
4
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
5
Racepinephrine Approved Phase 4 329-65-7 838
6
Sodium citrate Approved, Investigational Phase 4 68-04-2
7
Hexetidine Approved, Investigational Phase 4 141-94-6
8
Ofloxacin Approved Phase 4 82419-36-1 4583
9
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
10
Morphine Approved, Investigational Phase 4 57-27-2 5288826
11
tannic acid Approved Phase 4 1401-55-4
12
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
13
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
14
Amifostine Approved, Investigational Phase 4 20537-88-6 2141
15
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
16
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
17
Promethazine Approved, Investigational Phase 4 60-87-7 4927
18
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
19
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
20
Povidone Approved Phase 4 9003-39-8 131751496
21
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
22
Simethicone Approved Phase 4 8050-81-5
23
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
24
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
25
Castor oil Approved, Investigational, Nutraceutical, Vet_approved Phase 4 8001-79-4
26
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
27
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
28 Acidophilus Phase 4
29 Anti-Infective Agents, Local Phase 4
30 Vitamin B9 Phase 4
31 Vitamin B Complex Phase 4
32 Folate Phase 4
33 Ionophores Phase 4
34 Folic Acid Antagonists Phase 4
35
Bilirubin Phase 4 635-65-4 5280352
36 N-Methylaspartate Phase 4
37 Sodium hypochlorite Phase 4
38 Castor Phase 4
39 Epinephryl borate Phase 4
40 Eusol Phase 4
41 Disinfectants Phase 4
42 Citrate Phase 4
43 Ether Phase 4
44 Anti-Infective Agents Phase 4
45 Anti-Bacterial Agents Phase 4
46 Cytochrome P-450 Enzyme Inhibitors Phase 4
47 Analgesics Phase 4
48 Anesthetics Phase 4
49 Narcotics Phase 4
50 Analgesics, Opioid Phase 4

Interventional clinical trials:

(show top 50) (show all 258)
# Name Status NCT ID Phase Drugs
1 Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer Unknown status NCT01876407 Phase 4
2 Efficacy of Two Different Oral Hygiene Regimens on the Incidence and Severity of Oral Mucositis in Patients Receiving Hematopoietic Stem Cell Transplantation - A Randomized Controlled Trial Unknown status NCT02662374 Phase 4 .02% Chlorohexidine Gluconate;3% Sodium Bicarbonate;Nystatin 10000U/ml;Supersaturated Calcium Phosphate
3 A Randomized Study on the Effects of Lactobacillus Brevis CD2 in the Prevention of Radio and Chemotherapy Induced Oral Mucositis in Head and Neck Cancer Patients. Unknown status NCT01707641 Phase 4
4 Open-Label Single-Arm Phase IV Study of Pemetrexed in Taiwanese Patients With Advanced Non-Small Cell Lung Cancer Who Have Had Prior Chemotherapy Completed NCT00380718 Phase 4 pemetrexed
5 Photodynamic Therapy Against Candida Spp. in Complete Denture Wearers: a Randomized Clinical Trial Completed NCT02642900 Phase 4 Nystatin 100.000 units
6 Clinical Evaluation of an Experimental Solution Based on Ricinus Communis Compared to Sodium Hypochlorite for Denture Cleansing Completed NCT02407834 Phase 4
7 Local Administration of Morphine: An Evaluation of the Analgesic Effect at Stomatitis in Children Completed NCT00357942 Phase 4 morphine solution for injection;Placebo;morphine mouthwash;Placebo
8 Evaluation of the Efficacy of a Hexetidine- and Chlorobutanol-based Mouthwash in the Symptomatic Treatment of Oral Lesions Due to Removable Prostheses: a Prospective, Randomized, Triple-blind Controlled Clinical Trial Completed NCT01115049 Phase 4 chlorobutanol, hexetidine;Chlorhexidine
9 A Randomized, Double-blind Study to Evaluate the Efficacy of MuGard Mucoadhesive Oral Wound Rinse for the Amelioration of Oral Mucositis in Subjects Receiving Chemoradiation Therapy for the Treatment of Cancers of the Head and Neck Completed NCT01283906 Phase 4
10 Clinical Study of the Effects of Compound Kushen Injection on Radiation-induced Oral Mucositis in Head and Neck Cancer Patients. Recruiting NCT04204382 Phase 4 Levofloxacin Injection;Compound Kushen Injection(CKI)
11 A Comparison of Oral Controlled-release Morphine With Transdermal Fentanyl in Nasopharyngeal Cancer Patients With Moderate or Severe Oral Mucositis Pain Induced by Chemoradiotherapy Not yet recruiting NCT04292990 Phase 4 Fentanyl;Morphine
12 Prospective, Open-label, Randomized, Control Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine Suspended NCT01288625 Phase 4 Amifostine
13 An Adaptive Design, Single-Blind, Randomized, Controlled Study Investigating Polyvinylpyrrolidone (PVP) and Sodium Hyaluronate-Containing Oral Gel (Gelclair®) in Comparison to Viscous Lidocaine, Diphenhydramine, and Aluminum-magnesium Hydroxide/Simethicone Antacid Suspension Mouthwash ("Magic Mouthwash") for the Management of Oral Mucositis Associated With High Dose Chemotherapy and Methotrexate in Allogeneic Stem Cell Transplant Recipients Terminated NCT03490396 Phase 4
14 The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients Unknown status NCT01099891 Phase 3 rhEGF;Placebo
15 A Multinational, Multicenter, Double-Blind, Placebo-Controlled, Randomized, Phase III Clinical Trial to Determine the Efficacy and Safety of IB-367 Rinse in Reducing the Severity of Oral Mucositis in Patients Receiving Radiotherapy for Head and Neck Malignancy Unknown status NCT00022373 Phase 3 iseganan HCl oral solution
16 Evaluation of Low-energy Laser Therapy for Prevention and Reduction of Severity of Oral Mucositis in Children "Mucositis Laser 1" Unknown status NCT01007617 Phase 2, Phase 3
17 A Pilot Study on the Efficacy of Lactobacillus Brevis CD2 Lozenges in Preventing Oral Mucositis by High-dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplantation Unknown status NCT02085694 Phase 2, Phase 3 Lactobacillus brevis CD2
18 Laser Therapy Prevents Mucositis Oral in Patients Undergoing to Chemotherapy for Bone Marrow Transplantation? A Randomized Clinical Trial. Unknown status NCT02020928 Phase 3
19 A Double-Blind, Randomized, Vehicle-Controlled Study Comparing the Safety and Efficacy of Benzydamine HCl 0.15% Oral Rinse Including a Separate Open-Label Standard of Care Arm in Subjects With Radiation-Induced Mucositis Completed NCT00051441 Phase 3 Benzydamine Hydrochloride 0.15% Oral Rinse
20 Phase III Randomized Double-blind Cross-over Trial of Caphosol® Versus NaCl 0.9% in the Relief of Oral Mucositis in Renal Cell Carcinoma, Hepatocellular Carcinoma, and Gastrointestinal Stromal Tumor Patients Receiving Targeted Therapy Completed NCT01265810 Phase 3
21 Laser Therapy Associated With Photodynamic Therapy in the Treatment of Oral Mucositis Induced by Chemotherapy in Young Patients: Randomized Blind Clinical Trial Completed NCT02555501 Phase 3
22 Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic in Elderly People Completed NCT02818803 Phase 3 Miconazole
23 Effectiveness of Topical Hyaluronic Acid Versus Chlorhexidine Mouthwashes in the Treatment of Recurrent Aphthous Stomatitis: A Randomized Clinical Trial Completed NCT04265001 Phase 3 Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
24 Prevention of Recurrent Aphthous Stomatitis Using Vitamins Completed NCT00527306 Phase 3
25 Evaluating the Effectiveness of Topical Morphine Compared With a Routine Mouthwash in Managing Cancer Treatment-induced Mucositis in Patients With Head and Neck Cancer in Isfahan Completed NCT01837446 Phase 2, Phase 3 2% morphine solution;Magnesium aluminum hydroxide;2% viscous lidocaine;Diphenhydramine
26 A Phase 3, Randomized, Double-blind, Placebo-controlled Trial of Recombinant Human Keratinocyte Growth Factor for Reduction of Mucositis in Patients With Hematologic Malignancies Undergoing Total Body Irradiation and High-dose Chemotherapy With Autologous PBPC Transplantation Completed NCT00041665 Phase 3 Recombinant Human Keratinocyte Growth Factor
27 LAMPO: Multicenter Randomized Double-blind Controlled Trial to Evaluate the Efficacy of Laser Therapy for Treatment of Oral Mucositis Induced by Chemotherapy in Children Completed NCT02762019 Phase 3
28 A Randomized,Controlled Clinical Trial on the Efficacy and Safety of Chining Decoction in the Treatment of Radiation Stomatitis. Completed NCT02303197 Phase 3 ChiNing decoction
29 A Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Palifermin (Recombinant Human Keratinocyte Growth Factor) for Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer Receiving 5-FU and Leucovorin as Adjuvant Therapy Completed NCT00393822 Phase 2, Phase 3 palifermin;placebo
30 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Adjuvant Radiotherapy and Chemotherapy(RT/CT) Completed NCT00131638 Phase 3 Placebo;Palifermin
31 Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Radiotherapy With Concurrent Chemotherapy (RT/CT) Completed NCT00101582 Phase 3 Placebo;palifermin;cisplatin chemotherapy
32 Evaluation of Oral Care to Prevent Oral Mucositis in Estrogen Receptor Positive Metastatic Breast Cancer Patients Treated With Everolimus: Phase III Randomized Control Trial Completed NCT02376985 Phase 3 Everolimus
33 A Randomized, Blinded, Active-control Trial of Palifermin (rHuKGF) to Evaluate Oral Mucositis in Subjects With Hematologic Malignancies Undergoing Fractionated Total Body Irradiation (fTBI) and High Dose Chemotherapy With Autologous Peripheral Blood Progenitor Cell (PBPC) Transplantation Completed NCT00109031 Phase 3 palifermin;Cyclophosphamide;Etoposide;Placebo
34 A Comparison of Acute Oral Mucositis Between Morning and Afternoon Radiotherapy in Patients Receiving Radiation Treatment for Cancer of the Head and Neck Completed NCT00004234 Phase 3
35 A Randomized, Double-Blind, Placebo Controlled Trial Evaluating the Impact of Nystatin on the Development of Oral Irritation in Patients Receiving High Dose Intravenous Interleukin-2 Completed NCT00001812 Phase 3 Nystatin
36 Phase III Trial of Low-level Laser Therapy to Prevent Induced Oral Mucositis in Head and Neck Cancer Patients Submitted to Concurrent Chemoradiation Completed NCT01439724 Phase 3
37 Khon Kaen University Ethics Committee in Human Research Completed NCT02536781 Phase 2, Phase 3 Anthocyanin;Placebo
38 A Randomized Double-Blind Study of Doxepin Rinse Versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy Completed NCT01156142 Phase 3 doxepin hydrochloride
39 Effect of Ascorbic Acid Oral Supplementation in Assessing the Severity of Oral Mucositis in Chemo-radiation Therapy of Head and Neck Cancers. Completed NCT02868151 Phase 2, Phase 3 Ascorbic Acid;Zinc acetate
40 A Double-Blind, Randomized, Placebo-controlled Study of Two Different Schedules of Palifermin for Reduction in Severity of Oral Mucositis in Subjects With Multiple Myeloma Receiving Melphalan Followed by Autologous Blood Stem Cell Transplantation Completed NCT00434161 Phase 3 Palifermin before only;Placebo;Palifermin before and after
41 A Phase II/III Blinded Randomized Trial to Determine the Efficacy of Low Energy Diode Laser Therapy (650 nm or 780 nm) to Prevent Oral Mucositis Following Bone Marrow Transplantation Completed NCT00024037 Phase 2, Phase 3
42 Randomized Cross-over Study of Curcumin for Prevention of Oral Mucositis in Children Receiving Doxorubicin Based Chemotherapy. Completed NCT00475683 Phase 3
43 A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer Completed NCT00615420 Phase 3
44 Evaluate Safety and Tolerability and Compare Absorption/Distribution Kinetics of a Single 100 Mcg Dose of Fentanyl Sublingual Spray (Fentanyl SL Spray) in Cancer Subjects With or Without Oral Mucositis Completed NCT00956254 Phase 3 Fentanyl sublingual spray
45 A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy Completed NCT02229539 Phase 3 doxepin hydrochloride oral solution;DLA (diphenhydramine, lidocaine and antacids) rinse
46 A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation Completed NCT01305200 Phase 3 supersaturated calcium phosphate rinse
47 Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation : a Randomized Double Blind Multicenter Prospective Phase III Trial Completed NCT02696408 Phase 3
48 Clinical Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis as Adjunctive Therapy in Non-surgical Treatment of Periimplant Mucositis: a Randomized Controlled Trial Completed NCT04187222 Phase 3
49 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase III Clinical Study to Assess the Efficacy and Safety of SBG on Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT00790322 Phase 3 SBG
50 A Phase 2b/3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Comparing the Efficacy and Safety of Clonidine Mucoadhesive Buccal Tablet to Placebo to Prevent Chemoradiotherapy-induced Severe Oral Mucositis in Patients With Oropharyngeal Cancer Recruiting NCT04648020 Phase 2, Phase 3 Clonidine HCl Mucoadhesive Buccal Tablet;Placebo Mucoadhesive Buccal Tablet

Search NIH Clinical Center for Stomatitis

Inferred drug relations via UMLS 70 / NDF-RT 51 :


carbamide peroxide
Sucralfate

Cochrane evidence based reviews: stomatitis

Genetic Tests for Stomatitis

Anatomical Context for Stomatitis

MalaCards organs/tissues related to Stomatitis:

40
T Cells, Bone Marrow, Myeloid, Prostate, Colon, Breast, Endothelial

Publications for Stomatitis

Articles related to Stomatitis:

(show top 50) (show all 14952)
# Title Authors PMID Year
1
A phase I and pharmacokinetic study of OSI-7904L, a liposomal thymidylate synthase inhibitor in combination with oxaliplatin in patients with advanced colorectal cancer. 61 54
17520255 2008
2
DPYD*2A mutation: the most common mutation associated with DPD deficiency. 61 54
17165084 2007
3
Phase II trial of pralatrexate (10-propargyl-10-deazaaminopterin, PDX) in patients with unresectable malignant pleural mesothelioma. 54 61
17409804 2007
4
First-line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of a phase II study with a simplified biweekly schedule. 54 61
15550581 2004
5
Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy. 61 54
15539918 2004
6
Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients. 61 54
12352929 2002
7
Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil. 54 61
10473079 1999
8
Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy. 54 61
9007910 1997
9
High dose busulphan/cyclophosphamide for autologous bone marrow transplantation is associated with minimal non-hemopoietic toxicity. 54 61
7524888 1994
10
High dose of vesicular stomatitis virus-vectored Ebola virus vaccine causes vesicular disease in swine without horizontal transmission. 61
33719915 2021
11
Antimicrobial TiO2 nanocomposite coatings for surfaces, dental and orthopaedic implants. 61
33642937 2021
12
Composition's effect of Origanum Syriacum essential oils in the antimicrobial activities for the treatment of denture stomatitis. 61
32808051 2021
13
Biological and technical complications in root cap-retained overdentures after 3-15 years in situ: a retrospective clinical study. 61
32895768 2021
14
Treatment of oral fungal infections using photodynamic therapy: Systematic review and meta-analysis. 61
33797857 2021
15
Evaluation of the effect of probiotic lozenges in the treatment of recurrent aphthous stomatitis: a randomized, controlled clinical trial. 61
32820431 2021
16
Novel combination therapy of hydroxychloroquine and topical tacrolimus for chronic ulcerative stomatitis. 61
32970835 2021
17
Characterization of pseudotyped vesicular stomatitis virus bearing the heartland virus envelope glycoprotein. 61
33561699 2021
18
New Adjuvant Drug for Lung Cancer. 61
33755621 2021
19
The role of Mediterranean fever gene variants in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome. 61
33051715 2021
20
Comparison of patients' diagnoses in a dermatology outpatient clinic during the COVID-19 pandemic period and pre-pandemic period. 61
33332694 2021
21
FDA Approval Summary: Alpelisib Plus Fulvestrant for Patients with HR-positive, HER2-negative, PIK3CA-mutated, Advanced or Metastatic Breast Cancer. 61
33168657 2021
22
Everolimus after failure of one prior VEGF-targeted therapy in metastatic renal cell carcinoma: Final results of the MARC-2 trial. 61
33070307 2021
23
Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease. 61
33789012 2021
24
Suitability of two rapid lateral flow immunochromatographic assays for predicting SARS-CoV-2 neutralizing activity of sera. 61
33236799 2021
25
New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models. 61
33795383 2021
26
Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods. 61
33139905 2021
27
Antifungal property of acrylic denture soft liner containing silver nanoparticles synthesized in situ. 61
33524431 2021
28
Fibrin Biopolymer Incorporated with Antimicrobial Agents: A Proposal for Coating Denture Bases. 61
33810381 2021
29
Efficacy of Toluidine Blue-Mediated Antimicrobial Photodynamic Therapy on Candida spp. A Systematic Review. 61
33806003 2021
30
Effect of local hygiene protocols on denture-related stomatitis, biofilm, microbial load, and odor: A randomized controlled trial. 61
33736863 2021
31
Comparison of Antifungal Efficacy of Zataria Multiflora and Nystatin for Treatment of Denture Stomatitis: A Randomized Clinical Trial. 61
33681424 2021
32
Phytotherapy in the management of denture stomatitis: A systematic review and meta-analysis of randomized controlled trials. 61
33751681 2021
33
Isolation and Characterization of Cross-Reactive Human Monoclonal Antibodies That Potently Neutralize Australian Bat Lyssavirus Variants and Other Phylogroup 1 Lyssaviruses. 61
33804519 2021
34
Altered tonsillar toll-like receptor (TLR)-1 and TLR-2 expression levels between periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), and group A beta-hemolytic streptococcal (GAβHS) recurrent tonsillitis patients. 61
33725589 2021
35
Pistacia atlantica Desf. roots extract: LC-ESI-MS Analysis, antioxidant activity and gastroprotective effect on experimentally-induced ultrastructural gastric ulcers in mice. 61
33688798 2021
36
Geographic distribution and genetic characterization of poxviruses from human infections in Georgia, 2009-2014. 61
33745070 2021
37
Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes. 61
33653890 2021
38
Salivary irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients. 61
33755963 2021
39
Histoplasma stomatitis unveiled: Not all opportunistic infections get better after initiation of antiretroviral therapy. 61
33768869 2021
40
Serum levels of vitamin D in patients with recurrent aphthous stomatitis. 61
33754499 2021
41
Successful measures to prevent the spread of bovine papular stomatitis in a dairy farm. 61
33310999 2021
42
Decrease in treatment intensity predicts worse outcome in patients with locally advanced head and neck squamous cell carcinoma undergoing radiochemotherapy. 61
32671728 2021
43
Oral and pulmonary necrobacillosis in a juvenile reticulated giraffe. 61
33446090 2021
44
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination. 61
33684176 2021
45
Zebrafish as an animal model for the antiviral RNA interference pathway. 61
33507144 2021
46
Expression of porcine interferon-α and its bioactivity analysis in vitro and in vivo. 61
33051705 2021
47
Chemogenetic ON and OFF switches for RNA virus replication. 61
33649317 2021
48
Sensitive detection of integrated and free transcripts in chimeric antigen receptor T-cell manufactured cell products using droplet digital polymerase chain reaction. 61
33715950 2021
49
The engineered MARCH8-resistant VSV glycoprotein enhances lentiviral vector transduction. 61
33678011 2021
50
Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion. 61
33665226 2021

Variations for Stomatitis

Expression for Stomatitis

Search GEO for disease gene expression data for Stomatitis.

Pathways for Stomatitis

Pathways related to Stomatitis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 TNF RSAD2 NUP98 IL6 IFNA2 IFITM3
2
Show member pathways
12.71 TNF RSAD2 NUP98 IL6 IFNA2 DDX58
3 12.69 TNF IL6 IFNA2 DDX58 BST2
4
Show member pathways
12.55 TNF RSAD2 NUP98 IL6 IFNA2 IFITM3
5
Show member pathways
12.43 TNF IFNA2 DDX58 ATG5 ATG12
6
Show member pathways
12.3 IL6 IFNA2 CSF3 CSF2
7 12.29 TNF CSF2 ATG5 ATG12
8
Show member pathways
12.25 RSAD2 NUP98 IFNA2 IFITM3 IFITM2 DDX58
9
Show member pathways
12.22 TNF IL6 CSF3 CSF2
10 12.13 TNF IL6 IFNA2 ATG5 ATG12
11 11.87 TNF IL6 IFNA2 CSF3 CSF2
12 11.82 TNF IL6 CSF3 CSF2
13
Show member pathways
11.82 TNF RSAD2 IL6 IFNA2 IFITM3 IFITM2
14 11.76 TNF IL6 CSF2
15
Show member pathways
11.76 IL6 CSF3 CSF2
16 11.66 TNF IL6 IFNA2 CSF2
17
Show member pathways
11.55 TNF IL6 CSF2
18 11.45 TNF IL6 FGF7
19 11.45 TNF IL6 FGF7 CSF3 CSF2
20 11.43 TNF IL6 CSF3
21 11.42 TNF IL6 CSF3 CSF2
22 11.4 IL6 CSF3 CSF2
23 11.13 TNF IL6 CSF3 CSF2
24
Show member pathways
11.05 IFNA2 DDX58 ADAR
25 10.92 TNF IL6 FGF7 CSF3 CSF2

GO Terms for Stomatitis

Cellular components related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Atg12-Atg5-Atg16 complex GO:0034274 8.62 ATG5 ATG12

Biological processes related to Stomatitis according to GeneCards Suite gene sharing:

(show all 30)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 10.08 TP63 TNF NUP98 IL6 IFNA2 FGF7
2 innate immune response GO:0045087 10.04 RSAD2 IFITM3 IFITM2 DDX58 BST2 ADAR
3 immune system process GO:0002376 10.04 RSAD2 IFITM3 IFITM2 DDX58 BST2 ATG5
4 positive regulation of gene expression GO:0010628 10.01 TNF LDLR IL6 FGF7 DDX58 CSF2
5 immune response GO:0006955 9.99 TNF IL6 IFITM3 IFITM2 CSF3 CSF2
6 cytokine-mediated signaling pathway GO:0019221 9.95 TNF IL6 IFNA2 CSF3 CSF2
7 viral process GO:0016032 9.95 RSAD2 NUP98 LDLR DDX58 ATG5 ATG12
8 cellular response to lipopolysaccharide GO:0071222 9.88 TNF IL6 CSF3 CSF2
9 positive regulation of DNA-binding transcription factor activity GO:0051091 9.83 TNF IL6 DDX58 CSF3
10 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.82 IL6 FGF7 CSF3
11 positive regulation of interleukin-6 production GO:0032755 9.82 TNF IL6 DDX58
12 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.81 TNF IL6 CSF3
13 positive regulation of interleukin-8 production GO:0032757 9.77 TNF IL6 DDX58
14 humoral immune response GO:0006959 9.76 TNF IL6 IFNA2
15 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 TNF IL6 IFNA2 CSF2
16 negative regulation of viral genome replication GO:0045071 9.72 TNF RSAD2 IFITM3 IFITM2 BST2
17 response to interferon-gamma GO:0034341 9.65 IFITM3 IFITM2 BST2
18 positive regulation of neuroinflammatory response GO:0150078 9.63 TNF IL6
19 positive regulation of podosome assembly GO:0071803 9.63 TNF CSF2
20 negative regulation of viral entry into host cell GO:0046597 9.63 IFNA2 IFITM3 IFITM2
21 type I interferon signaling pathway GO:0060337 9.63 RSAD2 IFNA2 IFITM3 IFITM2 BST2 ADAR
22 negative regulation of lipid storage GO:0010888 9.62 TNF IL6
23 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.62 RSAD2 IL6
24 autophagy of nucleus GO:0044804 9.61 ATG5 ATG12
25 vascular endothelial growth factor production GO:0010573 9.61 TNF IL6
26 C-terminal protein lipidation GO:0006501 9.56 ATG5 ATG12
27 response to interferon-alpha GO:0035455 9.56 IFITM3 IFITM2 BST2 ADAR
28 response to interferon-beta GO:0035456 9.54 IFITM3 IFITM2 BST2
29 response to virus GO:0009615 9.5 TNF RSAD2 IFITM3 IFITM2 DDX58 BST2
30 defense response to virus GO:0051607 9.23 RSAD2 IL6 IFNA2 IFITM3 IFITM2 DDX58

Molecular functions related to Stomatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 IL6 FGF7 CSF3 CSF2
2 cytokine activity GO:0005125 9.02 TNF IL6 IFNA2 CSF3 CSF2

Sources for Stomatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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