MCID: STR005
MIFTS: 28

Stork Bite

Categories: Cardiovascular diseases

Aliases & Classifications for Stork Bite

MalaCards integrated aliases for Stork Bite:

Name: Stork Bite 12 15
Salmon Patch Nevus 12
Unna's Nevus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5806

Summaries for Stork Bite

MalaCards based summary : Stork Bite, also known as salmon patch nevus, is related to taylor's syndrome and breast angiosarcoma. An important gene associated with Stork Bite is RASA1 (RAS P21 Protein Activator 1), and among its related pathways/superpathways are ERK Signaling and Developmental Biology. Affiliated tissues include skin, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 73 Naevus flammeus nuchae, or colloquially stork bite, is a congenital capillary malformation present in... more...

Related Diseases for Stork Bite

Diseases related to Stork Bite via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 taylor's syndrome 10.3 SYNGAP1 RASA1
2 breast angiosarcoma 10.2 PROX1 FLT4
3 hemifacial spasm 10.2 VEGFA FLT4
4 kaposiform hemangioendothelioma 10.2 PROX1 FLT4
5 capillary lymphangioma 10.1 PROX1 FLT4
6 lymphangiosarcoma 10.1 PROX1 FLT4
7 intramuscular hemangioma 10.1 TEK PROX1
8 chylothorax, congenital 10.1 PROX1 FLT4
9 nodular regenerative hyperplasia 10.1 NOTCH2 JAG1
10 lymphangitis 10.1 PROX1 FLT4
11 gorham's disease 10.1 VEGFA FLT4
12 capillary malformations, congenital 10.0
13 nevus flammeus of nape of neck 10.0
14 venous malformations, multiple cutaneous and mucosal 10.0 TEK SYNGAP1 RASA1
15 angiokeratoma circumscriptum 10.0 VEGFA TEK
16 cardiofaciocutaneous syndrome 1 10.0 SYNGAP1 RASA1 NRAS
17 arteriovenous malformation 10.0 VEGFA TEK RASA1
18 deafness, autosomal recessive 71 10.0 PROX1 JAG1
19 lymphangioma 10.0 VEGFA PROX1 FLT4
20 malignant astrocytoma 10.0 VEGFA RASA1 PROM1 NES
21 spondylocostal dysostosis 3, autosomal recessive 10.0 RBPJ NOTCH2 JAG1
22 hajdu-cheney syndrome 10.0 RBPJ NOTCH2 JAG1
23 pyogenic granuloma 10.0 TEK NRAS
24 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 10.0 RBPJ NOTCH2 JAG1
25 alagille syndrome 1 9.9 RBPJ NOTCH2 JAG1
26 cardiovascular organ benign neoplasm 9.9 VEGFA SYNGAP1 RASA1 FLT4
27 patent ductus arteriosus 1 9.9 VEGFA NOTCH2 JAG1
28 adams-oliver syndrome 9.9 RBPJ NOTCH2 JAG1
29 spinal disease 9.9 VEGFA PROM1 NES
30 neurofibromatosis, type i 9.9 SYNGAP1 RASA1 NRAS
31 pilocytic astrocytoma 9.9 PROM1 NRAS NES
32 arteriovenous malformations of the brain 9.9 VEGFA TEK SYNGAP1 RASA1
33 central nervous system cancer 9.8 VEGFA PROM1 NES
34 klippel-trenaunay-weber syndrome 9.8 TEK SYNGAP1 RASA1 FLT4
35 gliosarcoma 9.8 VEGFA PROM1 NRAS NES
36 angiosarcoma 9.7 VEGFA TEK PROX1 FLT4
37 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 9.7 VEGFA NES MOG
38 capillary disease 9.6 VEGFA TEK PROX1 PROM1 FLT4
39 tetralogy of fallot 9.6 VEGFA RBPJ NOTCH2 JAG1 FLT4
40 medulloblastoma 9.4 VEGFA PROM1 NRAS NOTCH2 NES JAG1
41 hemangioma 9.4 VEGFA TEK PROX1 PROM1 JAG1 FLT4
42 capillary hemangioma 9.4 VEGFA TEK SYNGAP1 RASA1 PROX1 PROM1
43 nervous system disease 9.3 VEGFA PROM1 NES MOG

Graphical network of the top 20 diseases related to Stork Bite:



Diseases related to Stork Bite

Symptoms & Phenotypes for Stork Bite

GenomeRNAi Phenotypes related to Stork Bite according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.4 NRAS
2 Decreased viability GR00221-A-2 9.4 REL
3 Decreased viability GR00221-A-3 9.4 NRAS RASA1 REL TEK
4 Decreased viability GR00221-A-4 9.4 RASA1 REL
5 Decreased viability GR00301-A 9.4 REL
6 Decreased viability GR00381-A-1 9.4 RASA1
7 Decreased viability GR00386-A-1 9.4 RASA1
8 Decreased viability GR00402-S-2 9.4 TEK
9 Decreased mitotic index GR00110-A-0 8.65 REL

MGI Mouse Phenotypes related to Stork Bite:

46 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.34 JAG1 MOG NRAS OSTF1 PHGDH PROM1
2 cardiovascular system MP:0005385 10.33 FLT4 JAG1 NOTCH2 NRAS PHGDH PROM1
3 growth/size/body region MP:0005378 10.32 FLT4 JAG1 MOG NOTCH2 NRAS PHGDH
4 cellular MP:0005384 10.31 JAG1 MOG NOTCH2 NRAS PHGDH PROM1
5 mortality/aging MP:0010768 10.22 FLT4 JAG1 NOTCH2 NRAS PHGDH PROM1
6 embryo MP:0005380 10.19 FLT4 JAG1 NOTCH2 NRAS PHGDH RASA1
7 digestive/alimentary MP:0005381 10.16 FLT4 JAG1 NOTCH2 NRAS PROX1 RASA1
8 craniofacial MP:0005382 10.07 JAG1 NOTCH2 NRAS PHGDH RASA1 RBPJ
9 nervous system MP:0003631 10.07 ALCAM JAG1 MOG NOTCH2 PHGDH PROM1
10 integument MP:0010771 10.06 FLT4 JAG1 NOTCH2 NRAS RBPJ REL
11 muscle MP:0005369 10.02 FLT4 JAG1 MOG NOTCH2 PROX1 RASA1
12 liver/biliary system MP:0005370 9.98 FLT4 JAG1 NOTCH2 NRAS PROX1 REL
13 neoplasm MP:0002006 9.8 NOTCH2 NRAS PHGDH PROM1 RBPJ VEGFA
14 no phenotypic analysis MP:0003012 9.7 FLT4 JAG1 NOTCH2 NRAS PROM1 RASA1
15 normal MP:0002873 9.65 FLT4 JAG1 NOTCH2 NRAS PROM1 PROX1
16 vision/eye MP:0005391 9.4 ALCAM JAG1 MOG NOTCH2 NRAS OSTF1

Drugs & Therapeutics for Stork Bite

Search Clinical Trials , NIH Clinical Center for Stork Bite

Genetic Tests for Stork Bite

Anatomical Context for Stork Bite

MalaCards organs/tissues related to Stork Bite:

40
Skin

Publications for Stork Bite

Articles related to Stork Bite:

# Title Authors PMID Year
1
Small Macule on the Eyelid: Stork Bite or Something Else? 61
31122648 2020
2
Can you catch Ebola from a stork bite? Inductive reasoning influences generalization of perceived zoonosis risk. 61
29117192 2017
3
Capillary malformations: a classification using specific names for specific skin disorders. 61
25864701 2015
4
Histopathologic findings in Unna's nevus suggest it is a tardive congenital nevus. 61
19033929 2008
5
Unna's and Miescher's nevi: two different types of intradermal nevus: hypothesis concerning their histogenesis. 61
17414435 2007
6
[Diagnosis at a glance: It is only a stork bite]. 61
16805199 2006
7
Erythema occipitalis traumaticum and stork bite. 61
8190673 1994
8
Familial medial telangiectatic nevus: variant of nevus flammeus--port-wine stain. 61
8479968 1993
9
Is there an association between hemangioma and syndromes with dysmorphic features? 61
1956746 1991
10
Familial nevus flammeus of the forehead and Unna's nevus. 61
3978851 1985

Variations for Stork Bite

Expression for Stork Bite

Search GEO for disease gene expression data for Stork Bite.

Pathways for Stork Bite

Pathways related to Stork Bite according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.62 VEGFA TEK SYNGAP1 RBPJ RASA1 NRAS
2
Show member pathways
13.28 VEGFA TEK SYNGAP1 RBPJ RASA1 NRAS
3
Show member pathways
12.7 VEGFA TEK RBPJ NRAS NOTCH2 JAG1
4 12.62 VEGFA NRAS NOTCH2 JAG1 FLT4
5 12.54 VEGFA TEK RASA1 NRAS FLT4
6
Show member pathways
12.41 TEK REL RASA1 NRAS
7
Show member pathways
12.4 VEGFA REL RASA1 NRAS
8
Show member pathways
12.35 VEGFA TEK SYNGAP1 REL RASA1 NRAS
9 11.99 RBPJ PROM1 NOTCH2 JAG1
10
Show member pathways
11.93 RBPJ NOTCH2 JAG1
11
Show member pathways
11.91 SYNGAP1 RASA1 NRAS
12
Show member pathways
11.88 SYNGAP1 RASA1 NRAS
13 11.78 VEGFA PROX1 PROM1 NES ALCAM
14
Show member pathways
11.65 VEGFA RASA1 FLT4
15 11.41 RBPJ NOTCH2 JAG1
16 11.3 TEK PROX1 NOTCH2 JAG1 FLT4
17 11.21 VEGFA NRAS FLT4
18 10.98 RBPJ NOTCH2 JAG1
19 10.92 VEGFA PROM1 NOTCH2 NES MOG
20 10.84 VEGFA JAG1
21 10.79 VEGFA JAG1
22
Show member pathways
10.74 VEGFA FLT4

GO Terms for Stork Bite

Biological processes related to Stork Bite according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.98 VEGFA TEK PROX1 NOTCH2 NES JAG1
2 positive regulation of cell proliferation GO:0008284 9.97 VEGFA RBPJ PROX1 NOTCH2 FLT4
3 negative regulation of apoptotic process GO:0043066 9.93 VEGFA TEK RASA1 NOTCH2 FLT4
4 MAPK cascade GO:0000165 9.88 TEK SYNGAP1 RASA1 NRAS
5 positive regulation of MAPK cascade GO:0043410 9.8 VEGFA TEK FLT4
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.8 VEGFA TEK NOTCH2 FLT4
7 Notch signaling pathway GO:0007219 9.79 RBPJ NOTCH2 JAG1
8 angiogenesis GO:0001525 9.72 VEGFA TEK RBPJ JAG1 FLT4
9 hemopoiesis GO:0030097 9.69 RBPJ NOTCH2 JAG1
10 inflammatory response to antigenic stimulus GO:0002437 9.65 RBPJ NOTCH2
11 positive regulation of neural precursor cell proliferation GO:2000179 9.65 PROX1 NES
12 negative regulation of cell-matrix adhesion GO:0001953 9.64 RASA1 JAG1
13 neuronal stem cell population maintenance GO:0097150 9.64 PROX1 JAG1
14 myeloid dendritic cell differentiation GO:0043011 9.63 RBPJ NOTCH2
15 vascular endothelial growth factor signaling pathway GO:0038084 9.62 VEGFA FLT4
16 pulmonary valve morphogenesis GO:0003184 9.61 NOTCH2 JAG1
17 endothelial cell differentiation GO:0045446 9.61 PROX1 JAG1
18 retina morphogenesis in camera-type eye GO:0060042 9.6 PROX1 PROM1
19 lymphangiogenesis GO:0001946 9.59 PROX1 FLT4
20 lymph vessel development GO:0001945 9.58 PROX1 FLT4
21 positive regulation of protein kinase C signaling GO:0090037 9.56 VEGFA FLT4
22 morphogenesis of an epithelial sheet GO:0002011 9.55 NOTCH2 JAG1
23 sprouting angiogenesis GO:0002040 9.54 VEGFA TEK FLT4
24 glomerular visceral epithelial cell development GO:0072015 9.52 NOTCH2 JAG1
25 hepatocyte proliferation GO:0072574 9.48 PROX1 NOTCH2
26 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 9.46 VEGFA RBPJ
27 positive regulation of endothelial cell migration GO:0010595 9.46 VEGFA TEK PROX1 FLT4
28 cell fate determination GO:0001709 9.43 PROX1 NOTCH2 JAG1
29 ciliary body morphogenesis GO:0061073 9.4 NOTCH2 JAG1
30 Notch signaling involved in heart development GO:0061314 9.13 RBPJ NOTCH2 JAG1
31 positive regulation of endothelial cell proliferation GO:0001938 9.02 VEGFA TEK PROX1 NRAS FLT4

Sources for Stork Bite

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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