GAS
MCID: STR035
MIFTS: 23

Streptococcal Group a Invasive Disease (GAS)

Categories: Rare diseases

Aliases & Classifications for Streptococcal Group a Invasive Disease

MalaCards integrated aliases for Streptococcal Group a Invasive Disease:

Name: Streptococcal Group a Invasive Disease 52
Gas 52 42
Group a Streptococcal Infection 52
Group a Streptococcal Disease 52

Classifications:



Summaries for Streptococcal Group a Invasive Disease

MedlinePlus : 42 Everyone has gas. Most people pass gas 13 to 21 times a day. Passing gas through the mouth is called belching or burping. Passing gas through the anus is called flatulence. Most of the time gas does not have an odor. The odor comes from bacteria in the large intestine that release small amounts of gases that contain sulfur. Gas in the digestive tract comes from two sources: air that you swallow and the breakdown of undigested food by bacteria in the large intestine. Certain foods may cause gas. Foods that produce gas in one person may not cause gas in another. You can reduce the amount of gas you have by Drinking lots of water and non-fizzy drinks Eating more slowly so you swallow less air when you eat Avoiding milk products if you have lactose intolerance Medicines can help reduce gas or the pain and bloating caused by gas. If your symptoms still bother you, see your health care provider. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Streptococcal Group a Invasive Disease, also known as gas, is related to fasciitis and toxic shock syndrome. The drugs Vaccines and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and testes.

Wikipedia : 74 A group A streptococcal infection is an infection with group A streptococcus (GAS). Streptococcus... more...

Related Diseases for Streptococcal Group a Invasive Disease

Diseases in the Streptococcal Group a Invasive Disease family:

Streptococcal Group B Invasive Disease

Diseases related to Streptococcal Group a Invasive Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 fasciitis 10.4
2 toxic shock syndrome 10.4
3 necrotizing fasciitis 10.4
4 streptococcal toxic-shock syndrome 10.4
5 pharyngitis 10.3
6 exanthem 10.3
7 endometritis 10.3
8 tic disorder 10.3
9 rheumatic fever 10.2
10 obsessive-compulsive disorder 10.2
11 bacterial infectious disease 10.2
12 tonsillitis 10.2
13 acute kidney failure 10.2
14 chickenpox 10.2
15 necrotizing soft tissue infection 10.2
16 rheumatic fever-related antigen 10.1
17 cellulitis 10.1
18 purpura fulminans 10.1
19 erysipelas 10.1
20 adult respiratory distress syndrome 10.1
21 acute proliferative glomerulonephritis 10.1
22 purpura 10.1
23 reactive arthritis 10.1
24 compartment syndrome 10.1
25 gilles de la tourette syndrome 10.0
26 allergic hypersensitivity disease 10.0
27 diarrhea 10.0
28 peritonitis 10.0
29 myoclonus 10.0
30 glomerulonephritis 10.0
31 septic arthritis 10.0
32 impetigo 10.0
33 alcohol dependence 9.9
34 atrial standstill 1 9.9
35 optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy 9.9
36 attention deficit-hyperactivity disorder 9.9
37 ocular motor apraxia 9.9
38 hypocalcemia, autosomal dominant 1 9.9
39 dermatitis, atopic 9.9
40 streptococcus, group a, severity of infection by 9.9
41 complement factor h deficiency 9.9
42 kawasaki disease 9.9
43 cyanosis, transient neonatal 9.9
44 chorea, childhood-onset, with psychomotor retardation 9.9
45 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.9
46 deficiency anemia 9.9
47 chorioamnionitis 9.9
48 hemorrhagic cystitis 9.9
49 mastoiditis 9.9
50 ectopic pregnancy 9.9

Graphical network of the top 20 diseases related to Streptococcal Group a Invasive Disease:



Diseases related to Streptococcal Group a Invasive Disease

Symptoms & Phenotypes for Streptococcal Group a Invasive Disease

Drugs & Therapeutics for Streptococcal Group a Invasive Disease

Drugs for Streptococcal Group a Invasive Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 1
2 Neurotransmitter Agents Phase 1
3 Adrenergic Agonists Phase 1
4 Adrenergic beta-Agonists Phase 1
5 Adrenergic Antagonists Phase 1
6 Adrenergic beta-Antagonists Phase 1
7 Pharmaceutical Solutions Phase 1
8 Adrenergic Agents Phase 1
9 Bromoacetylalprenololmenthane Phase 1
10 Anti-Infective Agents, Local
11 Anti-Infective Agents
12 Anti-Bacterial Agents
13 Antibiotics, Antitubercular

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Group A Streptococcal Human Challenge Study: Building a Pharyngitis Model to Accelerate Vaccine Development Active, not recruiting NCT03361163 Phase 1
2 A Prospective Multi-Centre Study of the Performance of the Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Participants With Acute Pharyngitis Completed NCT03171350
3 The Hospital Based Incidence of Acute Rheumatic Fever and Rheumatic Heart Disease, Acute Post Streptococcal Glomerulonephritis and Invasive Group A Streptococcal Disease in Fiji Completed NCT00264771
4 Long Term Follow-up of Patients With Group A Streptococcal Infection Originating From the Genital Tract Completed NCT00299663
5 Genome-wide Association Study of Susceptibility to Rheumatic Heart Disease in Fiji and New Caledonia Completed NCT02188862
6 A Pilot Study of the Safety, Tolerability, and Effectiveness of Halo to Prevent Acute Upper Respiratory Disease and Respiratory Virus Infections Completed NCT02644135 Halo Oral Spray;Halo Placebo
7 Pilot Study of Strepic® Device for the Diagnosis of Group A Streptococcal Pharyngitis Recruiting NCT03777098
8 Preview Rapid Strep A Test Method Comparison Study Suspended NCT03907449
9 A Prospective Multi-Centre Study of the Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Participants With Acute Pharyngitis Withdrawn NCT03693495

Search NIH Clinical Center for Streptococcal Group a Invasive Disease

Genetic Tests for Streptococcal Group a Invasive Disease

Anatomical Context for Streptococcal Group a Invasive Disease

MalaCards organs/tissues related to Streptococcal Group a Invasive Disease:

40
Heart, Kidney, Testes, Tonsil, Skin, T Cells, Liver

Publications for Streptococcal Group a Invasive Disease

Articles related to Streptococcal Group a Invasive Disease:

(show top 50) (show all 378)
# Title Authors PMID Year
1
Clinical Application of Enhanced Recovery After Surgery in Perioperative Period of Laparoscopic Colorectal Cancer Surgery. 42
30614769 2019
2
Association between digestive symptoms and sleep disturbance: a cross-sectional community-based study. 42
30782128 2019
3
Consumption of a Fermented Milk Product Containing Bifidobacterium lactis CNCM I-2494 in Women Complaining of Minor Digestive Symptoms: Rapid Response Which Is Independent of Dietary Fibre Intake or Physical Activity. 42
30621211 2019
4
Clinical and laboratory characteristics of patients presenting to a tertiary care center emergency department with invasive group A streptococcal infections. 61
32009602 2020
5
Successful treatment of severe acute respiratory distress syndrome due to Group A streptococcus induced toxic shock syndrome in the third trimester of pregnancy-effectiveness of venoarterial extracorporeal membrane oxygenation: A case report. 61
31595595 2020
6
Group A Streptococcal Infection During Pregnancy and the Postpartum Period. 61
31917148 2020
7
A Case Study of Puerperal Group A Streptococcal Infection Complicated by Toxic Shock Syndrome. 61
31993244 2020
8
Systems immunology reveals a linked IgG3-C4 response in patients with acute rheumatic fever. 61
31742781 2020
9
Prevalence of group A Streptococcal infection in Africa to inform GAS vaccines for rheumatic heart disease: A systematic review and meta-analysis. 61
31864789 2019
10
[Acute necrotizing fasciitis complicated with multiple organ dysfunction: one case report]. 61
31898577 2019
11
Characterizing the role of tissue-type plasminogen activator in a mouse model of Group A streptococcal infection. 61
31009808 2019
12
Associations between common respiratory viruses and invasive group A streptococcal infection: A time-series analysis. 61
31237087 2019
13
Facial necrotising fasciitis following rhytidectomy. 61
31204188 2019
14
Genetics of rheumatic fever and rheumatic heart disease. 61
31519994 2019
15
Post-Streptococcal Reactive Arthritis (PSRA). 61
31393253 2019
16
Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae. 61
31373269 2019
17
A rare case of osteomyelitis of the clavicle in a child due to Group A streptococcal infection. 61
30975773 2019
18
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice. 61
30970258 2019
19
Neuropsychiatric consequences of childhood group A streptococcal infection: A systematic review of preclinical models. 61
30818033 2019
20
Orbital Inflammatory Syndrome Post Group A Streptococcal Infection - Case Series and Review of Literature. 61
29020538 2019
21
Streptococcal Serology in Acute Rheumatic Fever Patients: Findings From 2 High-income, High-burden Settings. 61
30256313 2019
22
International survey of paediatric infectious diseases consultants on the management of community-acquired pneumonia complicated by pleural empyema. 61
30051535 2019
23
Invasive group A streptococcal infection outbreaks of typeemm118 in a long-term care facility, and of type emm74 in the homeless population, Montréal, Quebec. 61
31524888 2019
24
HECT E3 Ubiquitin Ligase-Regulated Txnip Degradation Facilitates TLR2-Mediated Inflammation During Group A Streptococcal Infection. 61
31620121 2019
25
Heart transplantation outcomes for rheumatic heart disease: Analysis of international registry data. 61
30383907 2018
26
Acute Epiglottitis with Concurrent Pneumonia and Septic Shock in an Alcoholic Adult Patient. 61
30443621 2018
27
Fulminant group A streptococcal infection without gangrene in the extremities: Analysis of five autopsy cases. 61
29722472 2018
28
Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection. 61
29986727 2018
29
Recurrent invasive group A streptococcal infection with four-limb amputation in an immunocompetent child. 61
30061131 2018
30
Poststreptococcal reactive arthritis in Japan. 61
29606414 2018
31
Community outbreak of invasive group A streptococcus infection in Ontario, Canada. 61
31011300 2018
32
New Insights into the Role of Zinc Acquisition and Zinc Tolerance in Group A Streptococcal Infection. 61
29581188 2018
33
Recent patterns in antibiotic use for children with group A streptococcal infections in Japan. 61
29146149 2018
34
The role of social determinants of health in the risk and prevention of group A streptococcal infection, acute rheumatic fever and rheumatic heart disease: A systematic review. 61
29897915 2018
35
Dextromethorphan Attenuates NADPH Oxidase-Regulated Glycogen Synthase Kinase 3β and NF-κB Activation and Reduces Nitric Oxide Production in Group A Streptococcal Infection. 61
29581121 2018
36
Unusual case of suspected recurrent scarlet fever in a UK serviceman. 61
29653937 2018
37
Treatment of PANDAS and PANS: a systematic review. 61
29309797 2018
38
Paediatric acute rheumatic fever in developed countries: Neglected or negligible disease? Results from an observational study in Lombardy (Italy). 61
30094276 2018
39
Endogenous Group A Streptococcal Endophthalmitis in a Healthy 42-Year-Old Man: A Case Report. 61
30005734 2018
40
Group A Streptococcal bacteraemia. Experience at King Fahad Medical City in Riyadh, Saudi Arabia. 61
28917068 2017
41
Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection. 61
28924140 2017
42
Group A streptococci infection. A systematic clinical review exemplified by cases from an obstetric department. 61
28600919 2017
43
Group A Streptococcal Bacteremia following Streptococcal Pharyngitis in an Older Patient with Diabetes: A Case Report


. 61
28656020 2017
44
Acute Rheumatic Fever: Global Persistence of a Preventable Disease. 61
27776916 2017
45
Nonrheumatic myopericarditis post acute streptococcal pharyngitis: An uncommon cause of sore throat with ST segment elevation. 61
27939516 2017
46
Household transmission of invasive group A Streptococcus infections in England: a population-based study, 2009, 2011 to 2013. 61
28537550 2017
47
[An rare complication of scarlet fever : invasive group A streptococcal infection with streptococcal toxic shock syndrome]. 61
28387490 2017
48
Whole genome sequencing of group A Streptococcus: development and evaluation of an automated pipeline for emmgene typing. 61
28462035 2017
49
Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection. 61
28355251 2017
50
Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever. 61
27465618 2016

Variations for Streptococcal Group a Invasive Disease

Expression for Streptococcal Group a Invasive Disease

Search GEO for disease gene expression data for Streptococcal Group a Invasive Disease.

Pathways for Streptococcal Group a Invasive Disease

GO Terms for Streptococcal Group a Invasive Disease

Sources for Streptococcal Group a Invasive Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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