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MCID: STR007
MIFTS: 26

Stress Polycythemia

Categories: Blood diseases, Rare diseases
Genes Related diseases Publications Pathways
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Aliases & Classifications for Stress Polycythemia

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MalaCards integrated aliases for Stress Polycythemia:

Name: Stress Polycythemia 12 20 58 15 71
Polycythemia, Emotional 12
Stress Erythrocytosis 58
Gaisboeck's Syndrome 20
Gaisbock's Syndrome 12
Pseudopolycythaemia 20
Pseudopolycythemia 20
Gaisbock Syndrome 58

Characteristics:

Orphanet epidemiological data:

58
gaisbock syndrome
Age of onset: Adult;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Blood diseases
See all MalaCards categories (disease lists)
ICD10: 32 33
Orphanet: 58  
Rare haematological diseases


External Ids:

Disease Ontology 12 DOID:2838
NCIt 50 C27174
SNOMED-CT 67 191371001
ICD10 32 D75.1
ICD10 via Orphanet 33 D75.1
UMLS via Orphanet 72 C0541719 C2242785
Orphanet 58 ORPHA90041
UMLS 71 C0541719
Sources

Summaries for Stress Polycythemia

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MalaCards based summary : Stress Polycythemia, also known as polycythemia, emotional, is related to peripheral nervous system disease and neuropathy. An important gene associated with Stress Polycythemia is EPO (Erythropoietin), and among its related pathways/superpathways are HIF-1 signaling pathway and HIF-1-alpha transcription factor network. Related phenotype is normal.

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Related Diseases for Stress Polycythemia

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Diseases related to Stress Polycythemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 peripheral nervous system disease 29.5 EPO BDNF ALB
2 neuropathy 29.4 EPO BDNF ALB
3 polycythemia 10.2
4 esophagus carcinoma in situ 10.1 LDHA EPO
5 hypertensive encephalopathy 10.1 EPO ALB
6 renal artery disease 10.1 EPO ALB
7 miliary tuberculosis 10.1 EPO ALB
8 calciphylaxis 10.1 EPO ALB
9 analbuminemia 10.1 EPO ALB
10 red cell aplasia 10.1 EPO ALB
11 vitamin metabolic disorder 10.1 EPO ALB
12 hemosiderosis 10.1 EPO ALB
13 pure red-cell aplasia 10.1 EPO ALB
14 hypersplenism 10.1 EPO ALB
15 renal hypertension 10.1 EPO ALB
16 blood protein disease 10.1 EPO ALB
17 parathyroid gland disease 10.1 EPO ALB
18 secondary hyperparathyroidism 10.1 EPO ALB
19 hyperparathyroidism 10.1 EPO ALB
20 prolapse of urethra 10.1 LDHA ALB
21 thrombocytosis 10.0 EPO ALB
22 autonomic neuropathy 10.0 EPO ALB
23 uremia 10.0 EPO ALB
24 porphyria cutanea tarda 10.0 EPO ALB
25 porphyria 10.0 EPO ALB
26 hemoglobinopathy 10.0 EPO ALB
27 microvascular complications of diabetes 1 10.0 EPO ALB
28 iron deficiency anemia 10.0 GHRL EPO
29 functional gastric disease 10.0 GHRL ALB
30 hypothyroidism 10.0
31 myopathy 10.0
32 cardiac arrest 10.0 EPO ALB
33 apnea, obstructive sleep 10.0 GHRL ALB
34 peripheral vascular disease 10.0 EPO ALB
35 bone marrow cancer 10.0 EPO ALB
36 acquired immunodeficiency syndrome 9.9 EPO ALB
37 traumatic brain injury 9.9 EPO BDNF
38 non-alcoholic steatohepatitis 9.9 GHRL ALB
39 encephalomalacia 9.9 EPO BDNF
40 blood platelet disease 9.9 EPO ALB
41 hyperthyroidism 9.9 GHRL ALB
42 sexual disorder 9.9 BDNF ALB
43 neurogenic bladder 9.9 BDNF ALB
44 phenylketonuria 9.9 GHRL ALB
45 pain agnosia 9.9 BDNF ALB
46 agnosia 9.9 BDNF ALB
47 meningoencephalitis 9.9 BDNF ALB
48 ectodermal dysplasia 1, hypohidrotic, x-linked 9.9 BDNF ALB
49 cranial nerve disease 9.9 BDNF ALB
50 secondary progressive multiple sclerosis 9.9 BDNF ALB

Graphical network of the top 20 diseases related to Stress Polycythemia:



Diseases related to Stress Polycythemia
Sources

Symptoms & Phenotypes for Stress Polycythemia

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MGI Mouse Phenotypes related to Stress Polycythemia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.02 ALB BDNF EPO GHRL LDHA
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Drugs & Therapeutics for Stress Polycythemia

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Search Clinical Trials , NIH Clinical Center for Stress Polycythemia

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Genetic Tests for Stress Polycythemia

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Anatomical Context for Stress Polycythemia

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Publications for Stress Polycythemia

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Articles related to Stress Polycythemia:

(show all 18)
# Title Authors PMID Year
1
Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats. 61
24215938 2014
2
Measurement of blood volume and red cell mass: re-examination of 51Cr and 125I methods. 61
8931957 1996
3
Subclavian steal phenomenon associated with stress polycythemia. A case report. 61
7661388 1995
4
[Blood viscosity and cerebral blood flow in aged]. 61
8331818 1993
5
Thromboembolic complications of polycythemia: polycythemia vera versus smokers' polycythemia. 61
8445747 1993
6
[Evaluation of a one step sandwich enzymeimmunoassay for serum erythropoietin--serum erythropoietin values in polycythemia vera and related hematological disorders]. 61
8355412 1993
7
Severe ischemic process in a young man with central retinal vein occlusion. 61
3255872 1988
8
Burst-promoting activity in anemia and polycythemia. 61
3958512 1986
9
Stress polycythemia. 61
3837011 1985
10
Stress polycythemia. 61
3997770 1985
11
[Hematological study on stress erythrocytosis in the aged (author's transl)]. 61
529543 1979
12
Stress polycythemia--a pathophysiologic study. 61
165576 1975
13
"Stress" polycythemia and hypertension. 61
4406823 1974
14
Alcohol and stress erythrocytosis. 61
4121622 1973
15
Alcohol--a cause of stress erythrocytosis? 61
4121847 1973
16
[Pathology of pseudopolycythemia (stress erythrocytosis)]. 61
5672988 1968
17
Stress polycythemia. 61
6025191 1967
18
Stress erythrocytosis. 61
13032198 1953
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Variations for Stress Polycythemia

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Expression for Stress Polycythemia

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Search GEO for disease gene expression data for Stress Polycythemia.
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Pathways for Stress Polycythemia

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Pathways related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
HIF-1 signaling pathway 36
11.29 LDHA EPO
2
HIF-1-alpha transcription factor network 1
10.97 LDHA EPO
3
HIF1Alpha Pathway 63
10.69 LDHA EPO
4
Photodynamic therapy-induced HIF-1 survival signaling 1
10.19 LDHA EPO
Sources

GO Terms for Stress Polycythemia

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Cellular components related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 GHRL EPO BDNF ALB

Biological processes related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.43 GHRL EPO ALB
2 positive regulation of neuron projection development GO:0010976 9.37 EPO BDNF
3 response to nutrient GO:0007584 9.32 LDHA EPO
4 positive regulation of synapse assembly GO:0051965 9.16 GHRL BDNF
5 response to electrical stimulus GO:0051602 8.96 GHRL EPO
6 response to estrogen GO:0043627 8.8 LDHA GHRL EPO

Molecular functions related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GHRL EPO
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Sources for Stress Polycythemia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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