MCID: STR007
MIFTS: 27

Stress Polycythemia

Categories: Blood diseases, Rare diseases

Aliases & Classifications for Stress Polycythemia

MalaCards integrated aliases for Stress Polycythemia:

Name: Stress Polycythemia 12 52 58 15 71
Polycythemia, Emotional 12
Stress Erythrocytosis 58
Gaisboeck's Syndrome 52
Gaisbock's Syndrome 12
Pseudopolycythaemia 52
Pseudopolycythemia 52
Gaisbock Syndrome 58

Characteristics:

Orphanet epidemiological data:

58
gaisbock syndrome
Age of onset: Adult;

Classifications:

Orphanet: 58  
Rare haematological diseases


External Ids:

Disease Ontology 12 DOID:2838
NCIt 49 C27174
SNOMED-CT 67 36874002
ICD10 32 D75.1
ICD10 via Orphanet 33 D75.1
UMLS via Orphanet 72 C0541719 C2242785
Orphanet 58 ORPHA90041
UMLS 71 C0541719

Summaries for Stress Polycythemia

MalaCards based summary : Stress Polycythemia, also known as polycythemia, emotional, is related to polycythemia and ataxia and polyneuropathy, adult-onset. An important gene associated with Stress Polycythemia is EPO (Erythropoietin), and among its related pathways/superpathways are HIF-1 signaling pathway and HIF-1-alpha transcription factor network. Affiliated tissues include lung, and related phenotypes are homeostasis/metabolism and cardiovascular system

Related Diseases for Stress Polycythemia

Diseases related to Stress Polycythemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 polycythemia 10.2
2 ataxia and polyneuropathy, adult-onset 10.2
3 hypothyroidism 10.2
4 myopathy 10.2
5 peripheral nervous system disease 10.2
6 neuropathy 10.2
7 esophagus carcinoma in situ 9.9 LDHA EPO
8 thrombosis 9.9
9 iron deficiency anemia 9.8 GHRL EPO
10 folic acid deficiency anemia 9.7 EPO CYGB
11 epiglottis cancer 9.7 EPO CYGB
12 acquired polycythemia 9.7 EPO CYGB
13 splenic sequestration 9.6 EPO CYGB
14 sleep apnea 9.6 GHRL EPO
15 blood platelet disease 9.5 EPO CYGB
16 nutritional deficiency disease 9.4 GHRL EPO CYGB
17 deficiency anemia 9.3 GHRL EPO CYGB

Graphical network of the top 20 diseases related to Stress Polycythemia:



Diseases related to Stress Polycythemia

Symptoms & Phenotypes for Stress Polycythemia

MGI Mouse Phenotypes related to Stress Polycythemia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.8 CYGB DLL1 EHD4 EPO GHRL LDHA
2 cardiovascular system MP:0005385 9.72 CYGB DLL1 EHD4 EPO LDHA
3 muscle MP:0005369 9.46 CYGB DLL1 EPO MAP3K10
4 normal MP:0002873 9.35 DLL1 EPO GHRL LDHA MAP3K10
5 renal/urinary system MP:0005367 8.92 CYGB DLL1 EHD4 MAP3K10

Drugs & Therapeutics for Stress Polycythemia

Search Clinical Trials , NIH Clinical Center for Stress Polycythemia

Genetic Tests for Stress Polycythemia

Anatomical Context for Stress Polycythemia

MalaCards organs/tissues related to Stress Polycythemia:

40
Lung

Publications for Stress Polycythemia

Articles related to Stress Polycythemia:

(show all 19)
# Title Authors PMID Year
1
Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats. 61
24215938 2014
2
[Acute superior mesenteric artery thrombosis due to stress erythrocytosis]. 61
8642774 1996
3
Measurement of blood volume and red cell mass: re-examination of 51Cr and 125I methods. 61
8931957 1996
4
Subclavian steal phenomenon associated with stress polycythemia. A case report. 61
7661388 1995
5
Thromboembolic complications of polycythemia: polycythemia vera versus smokers' polycythemia. 61
8445747 1993
6
[Blood viscosity and cerebral blood flow in aged]. 61
8331818 1993
7
[Evaluation of a one step sandwich enzymeimmunoassay for serum erythropoietin--serum erythropoietin values in polycythemia vera and related hematological disorders]. 61
8355412 1993
8
Severe ischemic process in a young man with central retinal vein occlusion. 61
3255872 1988
9
Burst-promoting activity in anemia and polycythemia. 61
3958512 1986
10
Stress polycythemia. 61
3837011 1985
11
Stress polycythemia. 61
3997770 1985
12
[Hematological study on stress erythrocytosis in the aged (author's transl)]. 61
529543 1979
13
Stress polycythemia--a pathophysiologic study. 61
165576 1975
14
"Stress" polycythemia and hypertension. 61
4406823 1974
15
Alcohol and stress erythrocytosis. 61
4121622 1973
16
Alcohol--a cause of stress erythrocytosis? 61
4121847 1973
17
[Pathology of pseudopolycythemia (stress erythrocytosis)]. 61
5672988 1968
18
Stress polycythemia. 61
6025191 1967
19
Stress erythrocytosis. 61
13032198 1953

Variations for Stress Polycythemia

Expression for Stress Polycythemia

Search GEO for disease gene expression data for Stress Polycythemia.

Pathways for Stress Polycythemia

Pathways related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 LDHA EPO
2 10.97 LDHA EPO
3 10.69 LDHA EPO
4 10.19 LDHA EPO

GO Terms for Stress Polycythemia

Biological processes related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to nutrient GO:0007584 9.32 LDHA EPO
2 positive regulation of sprouting angiogenesis GO:1903672 9.26 GHRL DLL1
3 response to electrical stimulus GO:0051602 9.16 GHRL EPO
4 response to hypoxia GO:0001666 9.13 LDHA EPO CYGB
5 response to estrogen GO:0043627 8.8 LDHA GHRL EPO

Molecular functions related to Stress Polycythemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GHRL EPO

Sources for Stress Polycythemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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