Strongyloidiasis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: STR008 MIFTS: 51	Strongyloidiasis Categories: Gastrointestinal diseases, Infectious diseases, Neuronal diseases, Oral diseases, Rare diseases, Respiratory diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Expand all tables

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Aliases & Classifications for Strongyloidiasis

MalaCards integrated aliases for Strongyloidiasis:

Name: Strongyloidiasis ¹² ⁷⁴ ⁵² ⁵⁸ ⁵⁴ ³ ⁴³ ¹⁵ ¹⁷ ⁷¹ ³²

Disseminated Strongyloidiasis ¹² ⁷¹ ³²

Anguilluliasis ⁵⁸ ⁷¹

Infection by Strongyloides ¹²

Threadworm Infection ⁵²

Anguillulosis ⁵⁸

Enterobiasis ⁷¹

Characteristics:

Orphanet epidemiological data:

⁵⁸

strongyloidiasis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Neuronal diseases Skin diseases Respiratory diseases Gastrointestinal diseases Oral diseases

See all MalaCards categories (disease lists)

ICD10: ³² ³³

Certain infectious and parasitic diseases

Helminthiases

Strongyloidiasis

Cutaneous strongyloidiasis

Disseminated strongyloidiasis

Intestinal strongyloidiasis

Strongyloidiasis, unspecified

Orphanet: ⁵⁸

Rare infectious diseases

External Ids:

Disease Ontology ¹² DOID:10955

ICD9CM ³⁴ 127.2

MeSH ⁴³ D013322

NCIt ⁴⁹ C128398

SNOMED-CT ⁶⁷ 1214006

ICD10 ³² B78 B78.7 B78.9

MESH via Orphanet ⁴⁴ D013322

ICD10 via Orphanet ³³ B78.0 B78.1 B78.7 more

UMLS via Orphanet ⁷² C0038463 C0085810

Orphanet ⁵⁸ ORPHA76

EFO ¹⁷ EFO_0007501

UMLS ⁷¹ C0038463 C0085810 C0086227 more

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Summaries for Strongyloidiasis

CDC : ³ Strongyloidiasis is a disease caused by a nematode, or a roundworm, in the genus Strongyloides. Though there are over 40 species within this genus that can infect birds, reptiles, amphibians, livestock and other primates, Strongyloides stercoralis is the primary species that accounts for human disease. It sometimes infects primates, dogs and cats, and some dog and primate infecting strains have been shown to be capable of causing human infection. We do not know if cat-infecting strains can infect humans or not. The larvae are small; the longest reach about 600 µm in length-making them very difficult to see with the naked eye.

MalaCards based summary : Strongyloidiasis, also known as disseminated strongyloidiasis, is related to meningitis and schistosomiasis, and has symptoms including fever and pruritus. An important gene associated with Strongyloidiasis is IL5 (Interleukin 5), and among its related pathways/superpathways are TGF-Beta Pathway and Cytokine Signaling in Immune system. The drugs Albendazole and Diethylcarbamazine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are hematopoietic system and immune system

Disease Ontology : ¹² A parasitic helminthiasis infectious disease that involves infection of the intestine, lungs, skin and central nervous system with nematode Strongyloides stercoralis.

NIH Rare Diseases : ⁵² Strongyloidiasis is a parasitic disease caused by the roundworm Strongyloides stercoralis (S. stercoralis). People catch the infection when they come in contact with soil contaminated with the worms. While there are often no symptoms, abdominal pain, cough, diarrhea, rash, unintentional weight loss and vomiting may occur. The infection is treated with anti-worm medications such as ivermectin . Strongyloidiasis is found in tropical and subtropical areas, but can also be found in temperate regions, including the southern United States.

Wikipedia : ⁷⁴ Strongyloidiasis is a human parasitic disease caused by the nematode called Strongyloides stercoralis,... more...

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Related Diseases for Strongyloidiasis

Diseases related to Strongyloidiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 395)

#	Related Disease	Score	Top Affiliating Genes
1	meningitis	31.2	IL5 IL13 IFNG
2	schistosomiasis	30.9	IL5 IL13 IGHE IFNG
3	urticaria	30.9	IL5 IL13 IGHE
4	filariasis	30.7	LGALS3BP IL5 IGHE IFNG
5	hypereosinophilic syndrome	30.6	IL5 IL3 IL13 IGHE IFNG CCL11
6	toxocariasis	30.6	IL5 IGHE EPGN
7	diarrhea	30.5	TGFB1 IL5 IL3 IL13 IFNG
8	respiratory failure	30.4	IL5 IL13 IGHE CD4 CCL11
9	cystoisosporiasis	30.3	MT-CO1 CD4
10	lung disease	30.3	TGFB1 IL5 IL13 IFNG
11	t-cell lymphoblastic leukemia/lymphoma	30.3	IL5 IL3 CD7 CD4
12	trichuriasis	30.3	STH IL13 EPGN
13	norwegian scabies	30.2	IL5 CD4
14	allergic bronchopulmonary aspergillosis	30.2	IL5 IGHE IFNG
15	dermatitis	30.2	IL5 IL13 IGHE IFNG CCL11
16	necatoriasis	30.2	IL5 EPGN
17	intestinal tuberculosis	30.1	IFNG CD4
18	nocardiosis	30.1	IFNG CD4
19	giardiasis	30.1	TGFB1 STH CD79A CD4
20	bronchitis	30.1	IL5 IL13 IGHE CCL11
21	ancylostomiasis	30.1	MT-CO1 EPGN
22	drug allergy	30.1	IL5 IGHE CD4
23	leishmaniasis	30.1	TGFB1 IL5 IL13 IFNG
24	echinococcosis	30.1	MT-CO1 IL5 IGHE IFNG
25	immune deficiency disease	30.0	IL13 IFNG CD79A CD4
26	loiasis	30.0	STH IL5 IL13
27	bronchiolitis obliterans	30.0	TGFB1 IL13 IFNG
28	cryptococcosis	30.0	IL13 IFNG CD4
29	cryptosporidiosis	30.0	IFNG CD79A CD4 CCL11
30	ige responsiveness, atopic	30.0	IL5 IL13 IGHE IFNG
31	chagas disease	30.0	TGFB1 IFNG CD4
32	ascaris lumbricoides infection	29.9	STH IL5 IL13 IFNG EPGN
33	lung abscess	29.9	IFNG CD4
34	autoimmune disease	29.9	TGFB1 IL5 IL13 IFNG CD79A
35	pneumonia	29.9	IL5 IL13 IFNG CCL11
36	bronchiolitis	29.9	IL5 IL13 IFNG CCL11
37	pulmonary disease, chronic obstructive	29.9	TGFB1 IL5 IL13 CD4 CCL11
38	enterobiasis	29.9	STH MT-CO1 EPGN
39	toxoplasmosis	29.8	TGFB1 IL5 IFNG CD79A
40	folliculitis	29.8	IL5 IFNG CD4 CCL11
41	gastroenteritis	29.8	IL5 IL3 IFNG CCL11
42	cystic echinococcosis	29.7	MT-CO1 IGHE IFNG
43	pancytopenia	29.7	IL3 IFNG CD7 CD4
44	fascioliasis	29.7	MT-CO1 IFNG EPGN
45	conjunctivitis	29.7	IL5 IL13 IGHE IFNG CCL11
46	cysticercosis	29.6	STH MT-CO1 IGHE CD4
47	trichinosis	29.5	IL5 IL3 IL13 CD4
48	taeniasis	29.4	STH MT-CO1 CD4
49	t-cell adult acute lymphocytic leukemia	29.4	LTV1 HBZ CD7 CD4
50	inflammatory bowel disease	29.2	TGFB1 IL5 IL3 IL13 IFNG CCL11

Graphical network of the top 20 diseases related to Strongyloidiasis:

Sources

Symptoms & Phenotypes for Strongyloidiasis

UMLS symptoms related to Strongyloidiasis:

fever, pruritus

MGI Mouse Phenotypes related to Strongyloidiasis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	9.65	CCL11 CD4 CD7 CD79A EPGN HBZ
2	immune system	MP:0005387	9.36	CCL11 CD4 CD7 CD79A EPGN IFNG

Sources

Drugs & Therapeutics for Strongyloidiasis

Drugs for Strongyloidiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Albendazole

Approved, Vet_approved

Phase 3

54965-21-8

2082

Synonyms:

((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle

((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French]

(5-(propylthio)-1H-Benzimidazol-2-yl)carbamate methyl ester

(5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester

(5-(propylthio)-1H-Benzimidazol-2-yl)carbamic acid methyl ester

(5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester

(5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester

[5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester

[5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester

5-(propylthio)-2-carbomethoxyaminobenzimidazole

5-(propylthio)-2-Carbomethoxyaminobenzimidazole

5-(Propylthio)-2-carbomethoxyaminobenzimidazole

54965-21-8

A4673_FLUKA

A4673_SIGMA

AB00052377

AC-015

AC1L1CVL

AC1Q2YKD

AKOS000540882

Albendazol

Albendazol [INN-Spanish]

albendazole

Albendazole

Albendazole (JAN/USP/INN)

Albendazole [USAN:INN:BAN:JAN]

Albendazole armstrong brand

Albendazole Armstrong Brand

Albendazole diba brand

Albendazole Diba Brand

Albendazole fustery brand

Albendazole Fustery Brand

Albendazole hormona brand

Albendazole Hormona Brand

Albendazole liferpal brand

Albendazole Liferpal Brand

Albendazole monohydrochloride

Albendazole Monohydrochloride

Albendazole Noe-Socopharm Brand

Albendazole noé-socopharm brand

Albendazole pfizer brand

Albendazole Pfizer Brand

Albendazole sanicoopa brand

Albendazole Sanicoopa Brand

Albendazole valdecasas brand

Albendazole Valdecasas Brand

Albendazolum

Albendazolum [INN-Latin]

Albendoral

Albenza

Albenza (TN)

Albenza, Eskazole, Zentel, Andazol, Albendazole

Armstrong brand OF albendazole

Armstrong Brand of Albendazole

BAS 00439961

BB_SC-1386

Bendapar

BIDD:GT0615

Bilutac

BIM-0051849.0001

BPBio1_000038

BRD-K79131256-001-04-7

BSPBio_000034

BSPBio_002548

C01779

CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER

Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester

CAS-54965-21-8

CHEBI:16664

CHEBI:506787

CHEMBL1483

ChemDiv1_000190

ChemDivAM_000003

CID2082

CPD000036735

D00134

D015766

DB00518

Diba brand OF albendazole

Diba Brand of Albendazole

Digezanol

Disthelm

Disthelm, mediamix V

Disthelm, Mediamix V

DivK1c_000704

EINECS 259-414-7

Endoplus

Eskazole

Fustery brand OF albendazole

Fustery Brand of Albendazole

Gascop

HMS1568B16

HMS1922K04

HMS2090G19

HMS2093K13

HMS502D06

HMS587I14

Hormona brand OF albendazole

Hormona Brand of Albendazole

HSDB 7444

I01-0380

IDI1_000704

InChI=1/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

KBio1_000704

KBio2_002012

KBio2_004580

KBio2_007148

KBioGR_000801

KBioSS_002012

Liferpal brand OF albendazole

Liferpal Brand of Albendazole

LS-50618

Lurdex

Mediamix V disthelm

Mediamix V Disthelm

methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate

methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate

methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate

Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate

methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate

Methyl 5-(propylthio)-2-benzimidazolecarbamate

Methyl 5-(propyl-thio)-2-benzimidazolecarbamate

methyl N-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate

methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate

Methyl-5-[propylthio]-2-benzimidazole carbamate

Metiazol

MLS000069722

MolPort-000-726-929

MolPort-000-760-571

MolPort-001-932-918

Monohydrochloride, albendazole

Monohydrochloride, Albendazole

NCGC00016876-01

NCGC00016876-02

NCGC00022896-03

NCGC00022896-04

NCGC00022896-05

NCGC00022896-06

NCGC00022896-07

NINDS_000704

Noe Socopharm Brand of Albendazole

Noé socopharm brand OF albendazole

Noe-Socopharm Brand of Albendazole

Noé-socopharm brand OF albendazole

NSC 220008

NSC220008

O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate

O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate

O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamic acid

Oprea1_429292

Oprea1_585016

Oprea1_640007

Pfizer brand OF albendazole

Pfizer Brand of Albendazole

Prestwick_675

Prestwick0_000247

Prestwick1_000247

Prestwick2_000247

Prestwick3_000247

Proftril

S1640_Selleck

SAM002589939

Sanicoopa brand OF albendazole

Sanicoopa Brand of Albendazole

SK And F 62979

SK And F62979

SK And F-62979

SK&F 62979

SK&F62979

SK&F-62979

SKF 62979

SKF62979

SKF-62979

Smith Kline & French Brand of Albendazole

SmithKline beecham brand OF albendazole

SmithKline Beecham Brand of Albendazole

SMR000036735

SPBio_002253

Spectrum_001532

SPECTRUM1503903

Spectrum4_000201

Spectrum5_001567

STK387550

STL046130

STOCK2S-67946

TL8003543

UNII-F4216019LN

V Disthelm, mediamix

V Disthelm, Mediamix

Valbazen

Valdecasas brand OF albendazole

Valdecasas Brand of Albendazole

VU0239747-6

Zental

Zentel

ZINC17146904

Diethylcarbamazine

Approved, Investigational, Vet_approved

Phase 3

90-89-1

3052

Synonyms:

12672-34-3

1642-54-2 (citrate (1:1))

1-Diethylcarbamyl-4-methylpiperazine

4-23-00-00225 (Beilstein Handbook Reference)

5348-97-0

5348-97-0 (mono-hydrochloride)

8028-18-0

84L

90-89-1

AB00053457

AC1L1F2E

AI3-19612

AKOS003268016

Aventis brand OF diethylcarbamazine citrate

Bitirazine

BPBio1_000208

BRD-K45542189-048-05-6

BRN 0143029

BSPBio_000188

BSPBio_002179

C07968

Camin

Camin (TN)

Caracide

Carbamazine

Carbilazine

Caricide

CHEMBL684

CID3052

Citrate, diethylcarbamazine

Cypip

D07825

DB00711

Decacide

Diaethylcarbamazinum

Diethyl carbamazine

Diethylcarbamazin

diethylcarbamazine

Diethylcarbamazine

Diéthylcarbamazine

Diethylcarbamazine (INN)

Diethylcarbamazine [INN:BAN]

Diethylcarbamazine citrate

Diethylcarbamazine citrate (1:1)

Diethylcarbamazine citrate (1:2)

Diethylcarbamazine L-tartrate (1:1)

Diethylcarbamazine maleate

Diethylcarbamazine monohydrochloride

Diethylcarbamazine phosphate (1:1)

Diethylcarbamazinum

Diethylcarbamazinum [INN-Latin]

Dietilcarbamazina

Dietilcarbamazina [INN-Spanish]

Ditrazine base

Ditrazine Base

DivK1c_000548

EINECS 202-023-3

Ethodryl

FR-1031

Hetrazan

IDI1_000548

KBio1_000548

KBio2_001418

KBio2_003986

KBio2_006554

KBio3_001399

KBioGR_001081

KBioSS_001418

Loxuran

LS-110688

Luxuran

Maleate, diethylcarbamazine

MolPort-001-788-448

Monohydrochloride, diethylcarbamazine

N,N-Diethyl-4-methyl-1-piperazinecarboxamide

N,N-diethyl-4-methylpiperazine-1-carboxamide

NCGC00178778-01

NCGC00178778-02

NINDS_000548

Notezine

NSC1364

Prestwick0_000284

Prestwick1_000284

Prestwick2_000284

Prestwick3_000284

Spatonin

SPBio_001203

SPBio_002407

Spectrum_000938

Spectrum2_001022

Spectrum3_000390

Spectrum4_000511

Spectrum5_000877

UNII-V867Q8X3ZD

Azithromycin

Approved

Phase 3

83905-01-5

447043 55185

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Ivermectin

Approved, Investigational, Vet_approved

Phase 2, Phase 3

70288-86-7

6474909

Synonyms:

(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside

71827-03-7

AB00513813

AC1MJ4GR

AC1N7O27

BPBio1_000322

BRD-K24652731-001-02-7

BSPBio_000292

CHEMBL341047

CID11957587

CID4330618

CID6321424

CID6419971

CID6427057

EU-0100693

FT-0082656

HMS1568O14

HMS2089M09

I 8898

I8898_SIGMA

Ivermectin

IVERMECTIN

Ivermectina

Ivermectine

Ivermectinum

Lopac0_000693

MK-933

MLS001333247

MLS001333248

MLS002153248

MolPort-006-394-715

NCGC00094047-01

NCGC00094047-02

NCGC00094047-03

Prestwick_516

Prestwick2_000156

Prestwick3_000156

S1351_Selleck

SMR000857211

Nitazoxanide

Approved, Investigational, Vet_approved

Phase 2, Phase 3

55981-09-4

41684

Synonyms:

(2-((5-Nitro-2-thiazolyl)carbamoyl)phenyl)acetat

[2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate

2-(Acetolyloxy)-N-(5-nitro-2-thiazolyl)benzamide

2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate

2-Acetyloxy-N-[(5-nitro-2-thiazolyl)]benzamide

55981-09-4

AC-1302

AC1L26A1

AC1Q5NVY

Alinia

Alinia (TN)

AZT + Nitazoxanide

azt+ nitazoxanide

BRN 1225475

C12H9N3O5S

CHEMBL1401

CID41684

Colufase

Columbia brand 1 OF nitazoxanide

Columbia brand 2 OF nitazoxanide

Columbia brand 3 OF nitazoxanide

CPD000466367

Cryptaz

D02486

Daxon

Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide

DB00507

EINECS 259-931-8

FT-0082459

Heliton

HMS2051L04

I14-6011

LS-144176

MLS000759492

MLS001424074

MolPort-002-042-244

N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester)

N-(5-Nitrothiazol-2-yl)salicylamide acetate ester

NCGC00090774-01

NCI60_034935

NCIMech_000843

Nitaxozanid

Nitaxozanide

Nitazoxanid

Nitazoxanida

Nitazoxanida [INN-Spanish]

Nitazoxanide

NITAZOXANIDE

Nitazoxanide (USAN/INN)

Nitazoxanide [USAN:INN]

Nitazoxanidum

Nitazoxanidum [INN-Latin]

NSC 697855

NSC697855

NTZ

o-(N-(5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate

Oprea1_263587

Phavic-1

Romark brand 1 OF nitazoxanide

Romark brand 2 OF nitazoxanide

S1627_Selleck

Salicylamide, N-(5-nitro-2-thiazolyl)- acetate (ester)

Salicylamide, N-(5-nitro-2-thiazolyl)-, acetate (ester)

SAM001246708

SBB068315

SMR000466367

STK395664

Taenitaz

Tizoxanide glucuronide

UNII-SOA12P041N

ZINC03956788

Antiprotozoal Agents

Phase 3

Tubulin Modulators

Phase 3

Antimitotic Agents

Phase 3

Anti-Bacterial Agents

Phase 3

Antiparasitic Agents

Phase 2, Phase 3

Anti-Infective Agents

Phase 2, Phase 3

Anthelmintics

Phase 2

Milbemycin

Phase 2

Formaldehyde

Approved, Vet_approved

50-00-0

712

Synonyms:

Aldeide formica

Fannoform

Formaldehído

Formaldehyd

Formaldehyde

Formaldehyde solution

Formalin

FORMALIN

Formalina

Formaline

Formalith

Formic aldehyde

Formol

Methaldehyde

Methanal

Methyl aldehyde

Methylene glycol

Methylene oxide

Oxomethane

Oxomethylene

Oxymethylene

Paraform

Mebendazole

Approved, Vet_approved

31431-39-7

4030

Synonyms:

(5-Benzoyl-1H-benzimidazol-2-yl)-carbamate methyl ester

(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester

(5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester

(5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester

(5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester

2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester

2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI)

31431-39-7

46404_FLUKA

46404_RIEDEL

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester

5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester

AB00052203

abello Farmacia brand OF mebendazole

Abello Farmacia Brand of Mebendazole

AC-12064

AC1L1H98

AC1Q44DR

AKOS000539066

Anti worm

Anti Worm

Anti-worm

Anti-Worm

Ardeypharm brand OF mebendazole

Ardeypharm Brand of Mebendazole

Bantenol

Banworm

BAS 00341140

Besantin

BIDD:GT0087

Bio-0458

Bio-0803

Boots brand OF mebendazole

Boots Brand of Mebendazole

Boots threadworm treatment

Boots Threadworm Treatment

BPBio1_000257

BRD-K77987382-001-01-7

BRD-K77987382-001-06-6

BSPBio_000233

BSPBio_003178

Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester

Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI)

Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester

CAS-31431-39-7

CBDivE_010559

CCRIS 4479

CHEBI:6704

CHEMBL685

CID4030

CPD000036734

D00368

D008463

DB00643

Degort's brand OF mebendazole

Degort's Brand of Mebendazole

Diba brand OF mebendazole

Diba Brand of Mebendazole

DivK1c_000751

EINECS 250-635-4

Elfar brand OF mebendazole

Elfar Brand of Mebendazole

Equivurm Plus

Esteve brand OF mebendazole

Esteve Brand of Mebendazole

Healthypharm brand OF mebendazole

Healthypharm Brand of Mebendazole

HMS1536H11

HMS1568L15

HMS1921F03

HMS2090B03

HMS2092B15

HMS502F13

HSDB 3232

I06-2075

IDI1_000751

Janssen brand OF mebendazole

Janssen Brand of Mebendazole

KBio1_000751

KBio2_001778

KBio2_004346

KBio2_006914

KBio3_002398

KBioGR_000712

KBioSS_001778

Leidapharm brand OF mebendazole

Leidapharm Brand of Mebendazole

Lomper

LS-48951

M2523_FLUKA

M2523_SIGMA

Madicure

MBDZ

Mebendan

Mebendazol

Mebendazol [INN-Spanish]

mebendazole

Mebendazole

Mébendazole

Mebendazole (JAN/USP)

Mebendazole (JAN/USP/INN)

Mebendazole [USAN:INN:BAN:JAN]

Mebendazole(USAN)

MEBENDAZOLE, 99%

Mebendazolum

Mebendazolum [INN-Latin]

Mebenoazole

Mebenvet

Mebex

Mebutar

methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate

methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate

Methyl 5-benzoyl benzimidazole-2-carbamate

Methyl 5-benzoyl-2-benzimidazolecarbamate

Methyl 5-benzoyl-2-benzimidazolylcarbamate

Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate

methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate

methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate

MLS000028491

MolPort-000-765-625

MolPort-001-889-615

N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle

N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French]

N-2 (5-Benzoyl-benzimidazole) carbamate de methyle

N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French]

NCGC00016806-01

NCGC00016806-02

NCGC00021698-03

NCGC00021698-04

NCGC00021698-05

NCGC00021698-06

NINDS_000751

Norgine brand OF mebendazole

Norgine Brand of Mebendazole

Noverme

NSC 184849

NSC184849

Oprea1_278237

Oprea1_768530

Ovitelmin

Pantelmin

Pfizer brand OF mebendazole

Pfizer Brand of Mebendazole

Prestwick_310

Prestwick0_000217

Prestwick1_000217

Prestwick2_000217

Prestwick3_000217

Pripsen mebendazole

Pripsen Mebendazole

Probes1_000013

Probes2_000149

R 17,635

R 17635

R17635

R-17635

SAM002548959

SMR000036734

SPBio_001442

SPBio_002154

Spectrum_001298

SPECTRUM1501110

Spectrum2_001401

Spectrum3_001439

Spectrum4_000416

Spectrum5_001381

Sqworm

SSL Brand of Mebendazole

SSL Brand OF mebendazole

STK093862

Streger brand OF mebendazole

Streger Brand of Mebendazole

Sufil

Surfont

Taxandria brand OF mebendazole

Taxandria Brand of Mebendazole

Tedec meiji brand OF mebendazole

Tedec Meiji Brand of Mebendazole

Telmin

TimTec1_000869

TL8002405

UNII-81G6I5V05I

Vermicidin

Vermicol

Vermidil

Vermin

Vermirax

Vermox

Vermox (TN)

Verpanyl

Versid

Wormkuur

ZINC00121541

Disinfectants

Ether

Interventional clinical trials:

(show all 14)

#	Name	Status	NCT ID	Phase	Drugs
1	Randomized, Open-label, Multi Centre Phase III Clinical Trial on Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis	Completed	NCT01570504	Phase 3	Ivermectin
2	Efficacy and Safety of Ivermectin Versus Albendazole for Chronic Strongyloidiasis	Completed	NCT00765024	Phase 3	Ivermectin;ivermectin;Albendazole
3	A Cluster Randomised Trial of the Safety of Co-Administration of IDA (Ivermectin, Diethylcarbamazine and Albendazole) & Azithromycin for Integrated Treatment of Neglected Tropical Diseases	Completed	NCT03676140	Phase 3	Albendazole on Day 1;Ivermectin on Day 1;Diethylcarbamazine on day 1;Azithromycin on Day 1;Azithromycin on Day 8
4	A Comparative Study of Two Regimens of Ivermectin for the Treatment of Strongyloides Stercoralis Infection	Recruiting	NCT03605758	Phase 3	Ivermectin
5	Clinical Trial Evaluating Safety and Efficacy of Ivermectin and Nitazoxanide Combination as Adjuvant Therapy in COVID-19 Newly Diagnosed Egyptian Patients: A Tanta University Hope	Not yet recruiting	NCT04360356	Phase 2, Phase 3
6	Efficacy, Safety and Pharmacokinetics of Ascending Dosages of Moxidectin Alone and in Comparison to Ivermectin Against Strongyloidiasis Stercoralis in Adults: a Randomized Controlled Trial	Enrolling by invitation	NCT04056325	Phase 2	Moxidectin;Ivermectin;Placebo oral tablet
7	Multicenter, Double-blind, Randomized, Placebo-controlled Study to Assess the Efficacy, Safety and Tolerability of Ivermectin in Mild Virus-positive Subjects (SARS-CoV)-2 With or Without Symptoms	Not yet recruiting	NCT04407507	Phase 2	Ivermectin;Placebo
8	Community-based Approach for the Management of Soil-transmitted Helminthiasis in General and Strongyloidiasis in Particular in a Highly Endemic Area	Unknown status	NCT01308268		Ivermectin + Albendazole
9	Study of Patients With Known or Suspected Infection With Strongyloides Stercoralis	Completed	NCT00001245
10	Host Response to Infection and Treatment in Lymphatic Filarial Disease Strongyloidiasis in India	Completed	NCT00342576
11	Diagnosis of Neglected Tropical Diseases (NTDs) in Patients Presenting With Persistent Digestive Disorders (≥2 Weeks) in Côte d'Ivoire, Indonesia, Mali and Nepal	Completed	NCT02105714
12	Efficacy and Nutritional Assessment Following Albendazole and Combined Albendazole/Ivermectin Treatment for Intestinal Helminth Infections in Rural Guatemalan Schoolchildren	Completed	NCT00207753		albendazole vs. combined albendazole/ivermectin treatment
13	The Sero-prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands	Completed	NCT01080989
14	Study of Patients With Parasitic Infections of the Gastrointestinal Tract	Terminated	NCT00001162

Search NIH Clinical Center for Strongyloidiasis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :

Albendazole

Ivermectin

Mebendazole

Pyrantel

Pyrantel Pamoate

Thiabendazole

Cochrane evidence based reviews: strongyloidiasis

Sources

Genetic Tests for Strongyloidiasis

Sources

Anatomical Context for Strongyloidiasis

MalaCards organs/tissues related to Strongyloidiasis:

⁴⁰

Testes, Skin, T Cells, Lung, Eye, Kidney, Small Intestine

Sources

Publications for Strongyloidiasis

Articles related to Strongyloidiasis:

(show top 50) (show all 1897)

#	Title	Authors	PMID	Year
1	Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen. ⁶¹ ⁵⁴	Montes M...White AC	19513105	2009
2	Eosinophil-selective mediators in human strongyloidiasis. ⁶¹ ⁵⁴	Mir A...Rull S	16879311	2006
3	The mutual influence of nematode infection and allergy. ⁶¹ ⁵⁴	Negrao-Correa D...Teixeira MM	16210900	2006
4	Strongyloides ratti antigenic components recognized by IgE antibodies in immunoblotting as an additional tool for improving the immunodiagnosis in human strongyloidiasis. ⁵⁴ ⁶¹	Rodrigues RM...Costa-Cruz JM	15057354	2004
5	Heterologous antigen extract in ELISA for the detection of human IgE anti-Strongyloides stercoralis. ⁶¹ ⁵⁴	Costa-Cruz JM...Taketomi EA	14743666	2003
6	Immunoglobulin-E and anti-IgE treatment in lung disease. ⁵⁴ ⁶¹	Chitkara RK...Fick RB	11980283	2001
7	A three years follow-up of total serum IgE levels in three patients treated for strongyloidiasis. ⁶¹ ⁵⁴	Poirriez J	11802274	2001
8	Influence of human T-cell lymphocytotropic virus type 1 infection on serologic and skin tests for strongyloidiasis. ⁶¹ ⁵⁴	Porto AF...Carvalho EM	11716123	2001
9	HTLV-1 decreases Th2 type of immune response in patients with strongyloidiasis. ⁵⁴ ⁶¹	Porto AF...Carvalho EM	11589779	2001
10	L3 antigen-specific antibody isotype responses in human strongyloidiasis: correlations with larval output. ⁶¹ ⁵⁴	Atkins NS...Bundy DA	10587378	1999
11	Differentially enhanced cytokine gene expression in CD4+ and CD8+ T cells in mesenteric lymph nodes in rats infected with Nippostrongylus brasiliensis. ⁵⁴ ⁶¹	Matsuda S...Arizono N	10610496	1999
12	Interferon-gamma and interleukin-4 responses in relation to serum IgE levels in persons infected with human T lymphotropic virus type I and Strongyloides stercoralis. ⁵⁴ ⁶¹	Neva FA...Carvalho EM	9815251	1998
13	Humoral responses in human strongyloidiasis: correlations with infection chronicity. ⁵⁴ ⁶¹	Atkins NS...Bundy DA	9463683	1997
14	Total serum IgE and parasite-specific IgG and IgA antibodies in human strongyloidiasis. ⁵⁴ ⁶¹	Rossi CL...da Silva LJ	8115797	1993
15	Strongyloides stercoralis hyperinfection in a carrier of HTLV-I virus with evidence of selective immunosuppression. ⁶¹ ⁵⁴	Newton RC...Neva FA	1543206	1992
16	Regulatory T cell expansion resolves after effective strongyloidiasis treatment in subjects with HTLV-1 co-infection. ⁶¹	Hoces D...Montes M	32120049	2020
17	Diagnostic update for an unusual case: recurrent strongyloidiasis. ⁶¹	Wilkins D...Burns DS	30636686	2020
18	Strongyloides stercoralis hyperinfection syndrome presenting as mechanical ileus after short-course oral steroids for chronic obstructive pulmonary disease (COPD) exacerbation. ⁶¹	Rothe K...Slotta-Huspenina J	32087332	2020
19	The Global Prevalence of Strongyloides stercoralis Infection. ⁶¹	Buonfrate D...Bisoffi Z	32545787	2020
20	Autochthonous Human and Canine Strongyloides stercoralis Infection in Europe: Report of a Human Case in An Italian Teen and Systematic Review of the Literature. ⁶¹	Ottino L...Zammarchi L	32503315	2020
21	Case Report: Incidentally Discovered Strongyloides stercoralis Infection after Urinary Diversion. ⁶¹	Bhasin A...Flaherty JP	32228779	2020
22	Prevalence of Intestinal Parasites in a Low-Income Texas Community. ⁶¹	Singer R...Mejia R	32207401	2020
23	Phylogenetic relationships of Strongyloides species in carnivore hosts. ⁶¹	Ko PP...Nagayasu E	32502520	2020
24	Serological assays for the diagnosis of Strongyloides stercoralis infection: a systematic review and meta-analysis of diagnostic test accuracy. ⁶¹	Kalantari N...Gorgani-Firouzjaee T	32052848	2020
25	A Case-Control Study on the Association Between Intestinal Helminth Infections and Treatment Failure in Patients With Cutaneous Leishmaniasis. ⁶¹	Martinez DY...Verdonck K	32494582	2020
26	Pictorial Review of Thoracic Parasitic Diseases: A Radiologic Guide. ⁶¹	Fiorentini LF...Hochhegger B	31978430	2020
27	Performance of two serodiagnostic tests for loiasis in a Non-Endemic area. ⁶¹	Gobbi F...Bisoffi Z	32453734	2020
28	Hospitalization for Chagas disease, dengue, filariasis, leishmaniasis, schistosomiasis, strongyloidiasis, and Taenia solium taeniasis/cysticercosis, Italy, 2011-2016. ⁶¹	Tilli M...Zammarchi L	32418191	2020
29	Fatal Strongyloides stercoralis hyperinfection syndrome in an alcoholic diabetic patient from México ⁶¹	Rodriguez-Perez EG...Escandon-Vargas K	32463606	2020
30	Prevalence and risk factors of strongyloidiasis in patients with systemic lupus erythematosus in Southern Thailand. ⁶¹	Juthong S...Thongbun N	32183590	2020
31	Should We Screen HIV-Positive Migrants for Strongyloidiasis? ⁶¹	Theunissen C...Florence E	32443596	2020
32	A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin). ⁶¹	Ortiz-Martinez S...Spanish-Peruvian Chagas Htlv And Strongyloides Network	32375325	2020
33	Strongyloides stercoralis Hyper infection Syndrome. ⁶¹	Karanam L SK...Papireddy CKR	32419745	2020
34	Strongyloides stercoralis seropositivity is not associated with increased symptoms in a remote Aboriginal community. ⁶¹	Hansen M...Kearns T	32372503	2020
35	Cost-effectiveness of different strategies for screening and treatment of Strongyloides stercoralis in migrants from endemic countries to the European Union. ⁶¹	Wikman-Jorgensen PE...Requena-Mendez A	32461226	2020
36	Genomic studies on Strongyloides stercoralis in northern and western Thailand. ⁶¹	Aupalee K...Streit A	32404172	2020
37	Integrating testing for chronic strongyloidiasis within the Indigenous adult preventive health assessment system in endemic communities in the Northern Territory, Australia: An intervention study. ⁶¹	Page WA...Buettner P	32401755	2020
38	Update on the major imported helminth infections in travelers and migrants. ⁶¹	Norman FF...Lopez-Velez R	32250168	2020
39	Opportunistic tropical infections in immunosuppressed patients. ⁶¹	Shu Kurizky P...Martins Gomes C	32299676	2020
40	The Strongyloides stercoralis-hookworms association as a path to the estimation of the global burden of strongyloidiasis: A systematic review. ⁶¹	Fleitas PE...Krolewiecki AJ	32282827	2020
41	Transplant-related strongyloidiasis in solid organ transplant recipients in Saudi Arabia and the Gulf Cooperation Council countries. ⁶¹	Elzein F...Alsaeed M	31982623	2020
42	Parasitological and immunological aspects of oral and subcutaneous prednisolone treatment in rats experimentally infected with Strongyloides venezuelensis. ⁶¹	Couto BPD...Costa-Cruz JM	31958413	2020
43	Strongyloides Screening in Heart Transplant Candidates. ⁶¹	Rahman F...Taimur S	32465869	2020
44	Infection by Strongyloides stercoralis in immigrants with Chagas disease: evaluation of eosinophilia as screening method in primary care. ⁶¹	Dopico E...Vinuesa T	31845476	2020
45	Health of Special Immigrant Visa holders from Iraq and Afghanistan after arrival into the United States using Domestic Medical Examination data, 2014-2016: A cross-sectional analysis. ⁶¹	Kumar GS...Jentes ES	32231361	2020
46	[Recommendations for the screening for infectious diseases, mental health, and female genital mutilation in immigrant patients seen in Primary Care]. ⁶¹	Sequeira-Aymar E...Requena-Mendez A	31029458	2020
47	Imported Infections in Rural Mid-West United States - A Report from a Tertiary Care Center. ⁶¹	Meyer A...Christensen G	32308221	2020
48	Alcohol consumption alters anti-Strongyloides stercoralis antibodies production. ⁶¹	De Souza JN...Soares NM	31902530	2020
49	Strongyloidiasis screening in migrants living in Spain: systematic review and meta-analysis. ⁶¹	Salvador F...Molina I	31758828	2020
50	Development of immunochromatographic device as a point-of-care tool for serodiagnosis of human strongyloidiasis cases. ⁶¹	Sadaow L...Intapan PM	31758442	2020

Sources

Genes for Strongyloidiasis

Genes related to Strongyloidiasis (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	IL5	Interleukin 5	Protein Coding	17.69	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴ GeneCards inferred via : Publications (show sections)	11589779 16879311 19513105
2	IGHE	Immunoglobulin Heavy Constant Epsilon	Protein Coding	14.27	Novoseek inferred ⁵⁴ GeneCards inferred via : Publications (show sections)	11589779 11802274 8115797 (more) 14743666 11716123 15057354 10587378 11980283 16210900 10610496 1543206 9815251 9463683
3	IL13	Interleukin 13	Protein Coding	11.49	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	IFNG	Interferon Gamma	Protein Coding	11.31	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	LGALS3BP	Galectin 3 Binding Protein	Protein Coding	11.02	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	10.96	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	CD7	CD7 Molecule	Protein Coding	10.59	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	CD79A	CD79a Molecule	Protein Coding	6.66	GeneCards inferred via : Publications (show sections)
9	CD4	CD4 Molecule	Protein Coding	6.44	DISEASES inferred ¹⁵
10	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	6.31	GeneCards inferred via : Publications (show sections)
11	LTV1	LTV1 Ribosome Biogenesis Factor	Protein Coding	6.28	DISEASES inferred ¹⁵
12	STH	Saitohin	Protein Coding	6.21	DISEASES inferred ¹⁵
13	EPGN	Epithelial Mitogen	Protein Coding	6.12	DISEASES inferred ¹⁵
14	IL3	Interleukin 3	Protein Coding	6.01	DISEASES inferred ¹⁵
15	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	5.91	DISEASES inferred ¹⁵
16	HBZ	Hemoglobin Subunit Zeta	Protein Coding	5.64	DISEASES inferred ¹⁵
17	RIOK2	RIO Kinase 2	Protein Coding	5.64	DISEASES inferred ¹⁵

Sources

Variations for Strongyloidiasis

Sources

Expression for Strongyloidiasis

Search GEO for disease gene expression data for Strongyloidiasis.

Sources

Pathways for Strongyloidiasis

Pathways related to Strongyloidiasis according to GeneCards Suite gene sharing:

(show all 30)

#	Super pathways	Score	Top Affiliating Genes
1	TGF-Beta Pathway ⁶³ Show member pathways JAK-STAT Pathway ⁶³ JNK Pathway ⁶³ MAPK Family Pathway ⁶³ Regulation of eIF4 and p70S6K ⁶³ SOCS Pathway ⁶³	13.43	TGFB1 IL5 IL3 IL13 IFNG CD4
2	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	13.19	TGFB1 IL5 IL3 IL13 IGHE IFNG
3	PAK Pathway ⁶³ Show member pathways Antioxidant Action of Vitamin-C ⁶³ Epithelial Adherens Junctions ⁶³	13.18	TGFB1 IL5 IL3 IL13 CD4 CCL11
4	Pathways in cancer ³⁶	12.72	TGFB1 IL5 IL3 IL13 IFNG
5	Allograft rejection ¹ ³⁶ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	12.65	TGFB1 IL5 IL3 IL13 IFNG CD4
6	Th17 cell differentiation ³⁶ Show member pathways IL-22 Pathway ⁶³ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁶ Th1 and Th2 cell differentiation ³⁶	12.49	TGFB1 IL5 IL13 IFNG CD4
7	T cell receptor signaling pathway ³⁶ Show member pathways PD-L1 expression and PD-1 checkpoint pathway in cancer ³⁶ T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.48	TGFB1 IL5 IFNG CD4
8	Immune response Fc epsilon RI pathway ²² Show member pathways Fc epsilon RI signaling pathway ³⁶ Fc-epsilon receptor I signaling in mast cells ¹ Immune response BCR pathway ²² VEGF signaling pathway ³⁶	12.47	IL5 IL3 IL13 IGHE CD79A
9	JAK-STAT signaling pathway ³⁶ Show member pathways B-Cell Development ⁶³ IL-7 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴ Interleukin-19, 20, 22, 24 ⁶⁵ Jak/STAT Signaling Pathway ⁶⁴ Type III interferon signaling ¹	12.34	IL5 IL3 IL13 IFNG
10	IL-17 Family Signaling Pathways ⁶⁴ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁶ Interleukin-17 signaling ⁶⁵ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.21	IL5 IL13 IFNG CCL11
11	Immune response IFN alpha/beta signaling pathway ²² Show member pathways Cytokine Network ⁶³ Interferon alpha/beta signaling ⁶⁵ Regulation of IFNA signaling ⁶⁵	12.16	TGFB1 IL5 IL3 IL13 IFNG
12	Interleukin-4 and 13 signaling ⁶⁵	11.87	TGFB1 IL13 IGHE CCL11
13	Senescence and Autophagy in Cancer ¹	11.83	TGFB1 IL3 IFNG
14	IL27-mediated signaling events ¹ Show member pathways IL12 Signaling Pathway ⁶⁶ Th1 Differentiation ⁶⁴	11.82	TGFB1 IFNG CD4
15	Hematopoietic Stem Cells and Lineage-specific Markers ⁶⁴	11.78	IL5 IL3 IFNG CD79A CD4
16	Th17 Differentiation ⁶⁴ Show member pathways IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴	11.75	TGFB1 IFNG CD4
17	Hematopoietic cell lineage ³⁶	11.75	IL5 IL3 CD7 CD4
18	Glucocorticoid receptor regulatory network ¹	11.69	IL5 IL13 IFNG
19	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ¹	11.65	IL5 IL3 IFNG
20	Dendritic Cells Developmental Lineage Pathway ⁶⁴	11.63	TGFB1 IFNG CD4
21	IL4-mediated signaling events ¹	11.54	IL5 IGHE CCL11
22	Lung fibrosis ¹	11.53	TGFB1 IL5 IL13 CCL11
23	Innate Lymphoid Cells Differentiation ⁶⁴	11.46	IL5 IL13 IFNG CD7 CD4
24	Development and heterogeneity of the ILC family ¹	11.21	IL5 IL13 IFNG
25	OX40 Pathway ⁶³	11.09	IL5 IL13 IFNG
26	Th2 Differentiation ⁶⁴	11.02	IL5 IL13 IFNG CD4 CCL11
27	IL12 signaling mediated by STAT4 ¹	11	TGFB1 IL13 IFNG CD4
28	G-protein signaling_Rap2B regulation pathway ²²	10.91	TGFB1 IL5 IL3 IL13 CCL11
29	IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types ⁶⁴	10.66	TGFB1 IL5 IL13
30	Cytokines and Inflammatory Response ¹	10.56	TGFB1 IL5 IL3 IL13 IFNG CD4

Sources

GO Terms for Strongyloidiasis

Cellular components related to Strongyloidiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.56	TGFB1 LGALS3BP IL5 IL3 IL13 IFNG
2	extracellular region	GO:0005576	9.28	TGFB1 LGALS3BP IL5 IL3 IL13 IGHE
3	preribosome, small subunit precursor	GO:0030688	9.16	RIOK2 LTV1

Biological processes related to Strongyloidiasis according to GeneCards Suite gene sharing:

(show all 11)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of cell proliferation	GO:0008284	9.8	TGFB1 IL5 IL3 IFNG EPGN
2	MAPK cascade	GO:0000165	9.73	TGFB1 IL5 IL3 EPGN
3	adaptive immune response	GO:0002250	9.72	IGHE IFNG CD79A CD7 CD4
4	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	9.54	IL3 IL13 IFNG
5	cytokine-mediated signaling pathway	GO:0019221	9.5	TGFB1 IL5 IL3 IL13 IGHE CD4
6	response to vitamin D	GO:0033280	9.49	TGFB1 CD4
7	regulation of regulatory T cell differentiation	GO:0045589	9.48	TGFB1 IFNG
8	negative regulation of interleukin-17 production	GO:0032700	9.46	TGFB1 IFNG
9	positive regulation of peptidyl-tyrosine phosphorylation	GO:0050731	9.46	TGFB1 IL5 IL3 CD4
10	T cell activation	GO:0042110	9.43	TGFB1 CD7 CD4
11	immune response	GO:0006955	9.23	IL5 IL3 IL13 IGHE IFNG CD7

Molecular functions related to Strongyloidiasis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	growth factor activity	GO:0008083	9.26	TGFB1 IL5 IL3 EPGN
2	cytokine activity	GO:0005125	9.1	TGFB1 IL5 IL3 IL13 IFNG CCL11

Sources

Sources for Strongyloidiasis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia

Strongyloidiasis

Aliases & Classifications for Strongyloidiasis

MalaCards integrated aliases for Strongyloidiasis:

Characteristics:

Orphanet epidemiological data:

Classifications:

External Ids:

Summaries for Strongyloidiasis

Related Diseases for Strongyloidiasis

Diseases related to Strongyloidiasis via text searches within MalaCards or GeneCards Suite gene sharing:

Graphical network of the top 20 diseases related to Strongyloidiasis:

Symptoms & Phenotypes for Strongyloidiasis

UMLS symptoms related to Strongyloidiasis:

MGI Mouse Phenotypes related to Strongyloidiasis:

Drugs & Therapeutics for Strongyloidiasis

Drugs for Strongyloidiasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 71 / NDF-RT 50 :

Cochrane evidence based reviews: strongyloidiasis

Genetic Tests for Strongyloidiasis

Anatomical Context for Strongyloidiasis

MalaCards organs/tissues related to Strongyloidiasis:

Publications for Strongyloidiasis

Articles related to Strongyloidiasis:

Genes for Strongyloidiasis

Genes related to Strongyloidiasis (0 elite genes):

Variations for Strongyloidiasis

Expression for Strongyloidiasis

Pathways for Strongyloidiasis

Pathways related to Strongyloidiasis according to GeneCards Suite gene sharing:

GO Terms for Strongyloidiasis

Cellular components related to Strongyloidiasis according to GeneCards Suite gene sharing:

Biological processes related to Strongyloidiasis according to GeneCards Suite gene sharing:

Molecular functions related to Strongyloidiasis according to GeneCards Suite gene sharing:

Sources for Strongyloidiasis

Inferred drug relations via UMLS ⁷¹ / NDF-RT ⁵⁰ :