Structural Brain Anomalies with Impaired Intellectual Development and Craniosynostosis (BAIDCS)

External Ids:

OMIM 56 618736

OMIM : ⁵⁶ Patients with BAIDCS have small head circumference with abnormalities in brain anatomy including variable deficiency of the corpus callosum (including agenesis), abnormal conformation of the ventricles and posterior fossa, hypoplasia of both cerebellar hemispheres, colpocephaly, and partial rhombencephalosynapsis (absence of the cerebellar vermis with fusion of the cerebellar hemispheres). Intellectual development is moderately to severely impaired. Bicoronal synostosis, scoliosis, and tethered cord may be present (Twigg et al., 2015; Vandervore et al., 2018). Craniosynostosis-6 (CRS6; 616602) is an allelic disorder. (618736)

MalaCards based summary : Structural Brain Anomalies with Impaired Intellectual Development and Craniosynostosis, also known as baidcs, is related to craniosynostosis 6. An important gene associated with Structural Brain Anomalies with Impaired Intellectual Development and Craniosynostosis is ZIC1 (Zic Family Member 1). Affiliated tissues include brain and cerebellum.

Clinical features from OMIM:

618736

Search Clinical Trials , NIH Clinical Center for Structural Brain Anomalies with Impaired Intellectual Development and Craniosynostosis

Search GEO for disease gene expression data for Structural Brain Anomalies with Impaired Intellectual Development and Craniosynostosis.