Subacute Lymphocytic Thyroiditis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Subacute Lymphocytic Thyroiditis

MalaCards integrated aliases for Subacute Lymphocytic Thyroiditis:

Name: Subacute Lymphocytic Thyroiditis ¹² ¹⁵ ⁷¹

Classifications:

MalaCards categories:
Anatomical: Endocrine diseases Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7187

NCIt ⁴⁹ C35829

SNOMED-CT ⁶⁷ 18018005

UMLS ⁷¹ C1306804

Sources

Summaries for Subacute Lymphocytic Thyroiditis

MalaCards based summary : Subacute Lymphocytic Thyroiditis is related to graves disease 1 and thyroid carcinoma. An important gene associated with Subacute Lymphocytic Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are Allograft rejection and Thyroxine (Thyroid Hormone) Production. Affiliated tissues include thyroid, t cells and liver, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : ⁷⁴ Subacute lymphocytic thyroiditis is a form of thyroiditis. Subacute lymphocytic thyroiditis may occur at... more...

Sources

Related Diseases for Subacute Lymphocytic Thyroiditis

Diseases related to Subacute Lymphocytic Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)

#	Related Disease	Score	Top Affiliating Genes
1	graves disease 1	30.2	TSHR TPO TG
2	thyroid carcinoma	30.1	TSHR TPO TG
3	hyperthyroidism	29.2	TSHR TPO TG CRP
4	thyroiditis	29.2	TSHR TPO TG IL2 IFNA1
5	hypothyroidism	27.8	TSHR TPO TG IL2 IFNA1 CRP
6	acute thyroiditis	10.5	TPO TG
7	mechanical strabismus	10.5	TPO TG
8	familial thyroid dyshormonogenesis	10.5	TPO TG
9	nonencapsulated sclerosing carcinoma	10.5	TPO TG
10	goiter, multinodular 1, with or without sertoli-leydig cell tumors	10.4	TPO TG
11	transient congenital hypothyroidism	10.4	TSHR TPO
12	hashimoto encephalopathy	10.4	TSHR TPO
13	postsurgical hypothyroidism	10.4	TSHR TG
14	athyreosis	10.4	TSHR TG
15	neonatal thyrotoxicosis	10.4	TSHR TG
16	thyroid gland anaplastic carcinoma	10.3	TPO TG
17	papillary thyroid microcarcinoma	10.3	TSHR TG
18	benign struma ovarii	10.3	TSHR TG
19	struma ovarii	10.3	TSHR TG
20	iodine hypothyroidism	10.3	TSHR TPO TG
21	thyroid crisis	10.3	TSHR TPO TG
22	toxic diffuse goiter	10.3	TSHR TPO TG
23	endemic goiter	10.3	TSHR TPO TG
24	hypothyroidism, congenital, nongoitrous, 2	10.3	TSHR TPO TG
25	plummer's disease	10.3	TSHR TPO TG
26	nontoxic goiter	10.3	TSHR TPO TG
27	alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity	10.3	TSHR TPO TG
28	myxedema	10.3	TSHR TPO TG
29	congenital hypothyroidism	10.2	TSHR TPO TG
30	differentiated thyroid carcinoma	10.2	TSHR TPO TG
31	follicular adenoma	10.2	TSHR TPO TG
32	diabetes mellitus, insulin-dependent, 20	10.2	TPO TG
33	papillary carcinoma	10.2	TSHR TPO TG
34	hypothyroidism, congenital, nongoitrous, 1	10.2	TSHR TG
35	vitiligo-associated multiple autoimmune disease susceptibility 1	10.1	TPO TG IL2
36	thyroid gland disease	10.1	TSHR TPO TG
37	suppurative thyroiditis	10.0	TG CRP
38	thyroid lymphoma	10.0	TG PICALM FAS
39	red cell aplasia	10.0	IL2 IFNA1
40	pericoronitis	10.0	TCF21 CRP
41	autoimmune disease of endocrine system	10.0	TSHR TPO TG IL2
42	chronic orbital inflammation	9.9	TSHR CRP
43	external ear disease	9.9	UNK CRP
44	otitis externa	9.9	UNK CRP
45	paralytic ileus	9.9	TCF21 CRP
46	uremic pruritus	9.9	IL2 CRP
47	thyroid cancer, nonmedullary, 1	9.9
48	thyroid gland papillary carcinoma	9.9
49	thyroid tumor	9.9
50	stevens-johnson syndrome/toxic epidermal necrolysis	9.9	IL2 FAS

Graphical network of the top 20 diseases related to Subacute Lymphocytic Thyroiditis:

Sources

Symptoms & Phenotypes for Subacute Lymphocytic Thyroiditis

MGI Mouse Phenotypes related to Subacute Lymphocytic Thyroiditis:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	growth/size/body region	MP:0005378	10.11	CHD7 FAS FLNB IL2 PDE10A PICALM
2	hematopoietic system	MP:0005397	10.1	BIRC3 CHD7 CR2 FAS FLNB IL2
3	homeostasis/metabolism	MP:0005376	10.1	BIRC3 CHD7 CR2 CRP FAS FLNB
4	endocrine/exocrine gland	MP:0005379	10.01	CHD7 FAS IL2 TCF21 TG TPO
5	immune system	MP:0005387	9.97	BIRC3 CHD7 CR2 CRP FAS FLNB
6	limbs/digits/tail	MP:0005371	9.43	CHD7 FAS FLNB TG TPO TSHR
7	mortality/aging	MP:0010768	9.36	BIRC3 CHD7 CR2 FAS FLNB IL2

Sources

Drugs & Therapeutics for Subacute Lymphocytic Thyroiditis

Search Clinical Trials , NIH Clinical Center for Subacute Lymphocytic Thyroiditis

Sources

Genetic Tests for Subacute Lymphocytic Thyroiditis

Sources

Anatomical Context for Subacute Lymphocytic Thyroiditis

MalaCards organs/tissues related to Subacute Lymphocytic Thyroiditis:

⁴⁰

Thyroid, T Cells, Liver

Sources

Publications for Subacute Lymphocytic Thyroiditis

Articles related to Subacute Lymphocytic Thyroiditis:

(show all 11)

#	Title	Authors	PMID	Year
1	Painless thyroiditis associated to thyroid carcinoma: role of initial ultrasonography evaluation. ⁶¹	Valentini RB...Meyer EL	26421671	2016
2	Subacute lymphocytic thyroiditis after lobectomy in a patient with papillary thyroid carcinoma: a case report. ⁶¹	Choi YS...Kim JH	23286248	2013
3	Thyroiditis. ⁶¹	Bindra A...Braunstein GD	16734054	2006
4	[Prevalence of autoimmunological disorders of the thyroid in children in the Białystok population]. ⁶¹	Kretowski A...Kinalska I	17338121	2006
5	[Kikuchi's disease: a case report and literature review]. ⁶¹	Lozano Parras MA...Espinos Perez D	12831299	2003
6	Thyroiditis: differential diagnosis and management. ⁶¹	Slatosky J...Wahba H	10706157	2000
7	Clinical, laboratory, and scintigraphic manifestations of subacute and chronic thyroiditis. ⁶¹	Intenzo CM...Green P	8386991	1993
8	[Painful lymphocytic subacute thyroiditis]. ⁶¹	Cortazar A...Beitia JJ	1552759	1992
9	The various presentations of thyroiditis. Diagnostic considerations. ⁶¹	Hamburger JI	3511814	1986
10	Thyroiditis: a clinical update. ⁶¹	Hay ID	3906289	1985
11	Subacute thyroiditis. ⁶¹	Volpe R	7033979	1981

Sources

Genes for Subacute Lymphocytic Thyroiditis

Genes related to Subacute Lymphocytic Thyroiditis (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TG	Thyroglobulin	Protein Coding	6.34	DISEASES inferred ¹⁵
2	FLNB	Filamin B	Protein Coding	5.8	DISEASES inferred ¹⁵
3	TPO	Thyroid Peroxidase	Protein Coding	5.64	DISEASES inferred ¹⁵
4	TCF21	Transcription Factor 21	Protein Coding	5.35	DISEASES inferred ¹⁵
5	UNK	Unk Zinc Finger	Protein Coding	4.59	DISEASES inferred ¹⁵
6	PDE10A	Phosphodiesterase 10A	Protein Coding	4.57	DISEASES inferred ¹⁵
7	PICALM	Phosphatidylinositol Binding Clathrin Assembly Protein	Protein Coding	4.36	DISEASES inferred ¹⁵
8	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	3.88	DISEASES inferred ¹⁵
9	CHD7	Chromodomain Helicase DNA Binding Protein 7	Protein Coding	3.86	DISEASES inferred ¹⁵
10	BIRC3	Baculoviral IAP Repeat Containing 3	Protein Coding	3.77	DISEASES inferred ¹⁵
11	IL2	Interleukin 2	Protein Coding	3.74	DISEASES inferred ¹⁵
12	CYP2B6	Cytochrome P450 Family 2 Subfamily B Member 6	Protein Coding	3.73	DISEASES inferred ¹⁵
13	CR2	Complement C3d Receptor 2	Protein Coding	3.68	DISEASES inferred ¹⁵
14	FAS	Fas Cell Surface Death Receptor	Protein Coding	3.38	DISEASES inferred ¹⁵
15	CRP	C-Reactive Protein	Protein Coding	3.35	DISEASES inferred ¹⁵
16	IFNA1	Interferon Alpha 1	Protein Coding	3.28	DISEASES inferred ¹⁵

Sources

Variations for Subacute Lymphocytic Thyroiditis

Sources

Expression for Subacute Lymphocytic Thyroiditis

Search GEO for disease gene expression data for Subacute Lymphocytic Thyroiditis.

Sources

Pathways for Subacute Lymphocytic Thyroiditis

Pathways related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Allograft rejection ¹ ³⁶ Show member pathways Antigen processing and presentation ³⁶ Asthma ³⁶ Autoimmune thyroid disease ³⁶ CTL Mediated Apoptosis ⁶³ Graft-versus-host disease ³⁶ Intestinal immune network for IgA production ³⁶ THC Differentiation Pathway ⁶³ Type I diabetes mellitus ³⁶ Viral myocarditis ³⁶	12.17	TSHR TPO TG IL2 IFNA1 FAS
2	Thyroxine (Thyroid Hormone) Production ¹	9.58	TSHR TPO TG

Sources

GO Terms for Subacute Lymphocytic Thyroiditis

Biological processes related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone biosynthetic process	GO:0042446	8.96	TPO TG
2	B cell differentiation	GO:0030183	8.8	TSHR IFNA1 CR2

Molecular functions related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	low-density lipoprotein particle receptor binding	GO:0050750	8.62	PICALM CRP

Sources

Sources for Subacute Lymphocytic Thyroiditis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia