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MCID: SBC005
MIFTS: 27

Subacute Lymphocytic Thyroiditis

Categories: Endocrine diseases, Immune diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Subacute Lymphocytic Thyroiditis

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MalaCards integrated aliases for Subacute Lymphocytic Thyroiditis:

Name: Subacute Lymphocytic Thyroiditis 12 15 71

Classifications:

MalaCards categories:
Anatomical: Endocrine diseases Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:7187
NCIt 50 C35829
SNOMED-CT 67 361126006
UMLS 71 C1306804
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Summaries for Subacute Lymphocytic Thyroiditis

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MalaCards based summary : Subacute Lymphocytic Thyroiditis is related to graves disease 1 and thyroid carcinoma. An important gene associated with Subacute Lymphocytic Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are PAK Pathway and Allograft rejection. Affiliated tissues include thyroid, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 74 Subacute lymphocytic thyroiditis is a form of thyroiditis. Subacute lymphocytic thyroiditis may occur at... more...

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Related Diseases for Subacute Lymphocytic Thyroiditis

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Diseases related to Subacute Lymphocytic Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 134)
# Related Disease Score Top Affiliating Genes
1 graves disease 1 30.2 TSHR TPO TG
2 thyroid carcinoma 30.2 TSHR TPO TG
3 hyperthyroidism 30.2 TSHR TPO TG
4 thyroiditis 29.9 TSHR TPO TG IL2
5 hypothyroidism 29.8 TSHR TPO TG IL2
6 acute thyroiditis 10.3 TPO TG
7 mechanical strabismus 10.3 TPO TG
8 nonencapsulated sclerosing carcinoma 10.3 TPO TG
9 aspirin allergy 10.3 TPO TG
10 goiter, multinodular 1, with or without sertoli-leydig cell tumors 10.3 TPO TG
11 struma ovarii 10.3 TSHR TG
12 athyreosis 10.3 TSHR TG
13 transient congenital hypothyroidism 10.3 TSHR TPO
14 hypotropia 10.3 TSHR TPO
15 type 1 diabetes mellitus 20 10.3 TPO TG
16 papillary thyroid microcarcinoma 10.3 TSHR TG
17 dendritic cell thymoma 10.2 TG CD4
18 hyperthyroxinemia 10.2 TSHR TPO
19 anal spasm 10.2 TG CD4
20 adrenal cortical hypofunction 10.2 TPO TG
21 thyroid hormone resistance, generalized, autosomal dominant 10.2 TSHR TG
22 iodine hypothyroidism 10.1 TSHR TPO TG
23 goiter 10.1 TSHR TPO TG
24 thyroid crisis 10.1 TSHR TPO TG
25 toxic diffuse goiter 10.1 TSHR TPO TG
26 postsurgical hypothyroidism 10.1 TSHR TPO TG
27 endemic goiter 10.1 TSHR TPO TG
28 nontoxic goiter 10.1 TSHR TPO TG
29 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1 TSHR TPO TG
30 myxedema 10.1 TSHR TPO TG
31 subacute thyroiditis 10.1 TSHR TPO TG
32 exophthalmos 10.1 TSHR TPO TG
33 congenital hypothyroidism 10.1 TSHR TPO TG
34 invasive malignant thymoma 10.1 TSHR CD4
35 benign struma ovarii 10.1 TSHR TG TCF21
36 thyroid lymphoma 10.1 TG FAS
37 differentiated thyroid carcinoma 10.1 TSHR TPO TG
38 hypothyroidism, congenital, nongoitrous, 1 10.1 TSHR TG
39 follicular adenoma 10.1 TSHR TPO TG
40 papillary carcinoma 10.1 TSHR TPO TG
41 hypothyroidism, congenital, nongoitrous, 2 10.1 TSHR TG
42 thyroid gland follicular carcinoma 10.1 TSHR TPO TG
43 thyroid gland anaplastic carcinoma 10.1 TSHR TPO TG
44 skin sarcoidosis 10.1 IL2 CD4
45 metal allergy 10.1 IL2 CD4
46 gallbladder lymphoma 10.1 CR2 BIRC3
47 oral tuberculosis 10.1 IL2 CD4
48 splenic tuberculosis 10.1 IL2 CD4
49 superficial basal cell carcinoma 10.1 IL2 CD4
50 farmer's lung 10.1 IL2 CD4

Graphical network of the top 20 diseases related to Subacute Lymphocytic Thyroiditis:



Diseases related to Subacute Lymphocytic Thyroiditis
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Symptoms & Phenotypes for Subacute Lymphocytic Thyroiditis

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MGI Mouse Phenotypes related to Subacute Lymphocytic Thyroiditis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.06 BIRC3 CD4 CR2 FAS FLNB IL2
2 homeostasis/metabolism MP:0005376 10.03 BIRC3 CD4 CR2 EMP1 FAS FLNB
3 growth/size/body region MP:0005378 10.02 CD4 FAS FLNB IL2 SELL TCF21
4 endocrine/exocrine gland MP:0005379 10.01 CD4 FAS IL2 SELL TCF21 TG
5 immune system MP:0005387 9.9 BIRC3 CD4 CR2 FAS FLNB IL2
6 mortality/aging MP:0010768 9.65 BIRC3 CD4 CR2 FAS FLNB IL2
7 neoplasm MP:0002006 9.02 FAS IL2 SELL TCF21 TSHR
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Drugs & Therapeutics for Subacute Lymphocytic Thyroiditis

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Search Clinical Trials , NIH Clinical Center for Subacute Lymphocytic Thyroiditis

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Genetic Tests for Subacute Lymphocytic Thyroiditis

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Anatomical Context for Subacute Lymphocytic Thyroiditis

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MalaCards organs/tissues related to Subacute Lymphocytic Thyroiditis:

40
Thyroid
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Publications for Subacute Lymphocytic Thyroiditis

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Articles related to Subacute Lymphocytic Thyroiditis:

(show all 11)
# Title Authors PMID Year
1
Painless thyroiditis associated to thyroid carcinoma: role of initial ultrasonography evaluation. 61
26421671 2016
2
Subacute lymphocytic thyroiditis after lobectomy in a patient with papillary thyroid carcinoma: a case report. 61
23286248 2013
3
Thyroiditis. 61
16734054 2006
4
[Prevalence of autoimmunological disorders of the thyroid in children in the Białystok population]. 61
17338121 2006
5
[Kikuchi's disease: a case report and literature review]. 61
12831299 2003
6
Thyroiditis: differential diagnosis and management. 61
10706157 2000
7
Clinical, laboratory, and scintigraphic manifestations of subacute and chronic thyroiditis. 61
8386991 1993
8
[Painful lymphocytic subacute thyroiditis]. 61
1552759 1992
9
The various presentations of thyroiditis. Diagnostic considerations. 61
3511814 1986
10
Thyroiditis: a clinical update. 61
3906289 1985
11
Subacute thyroiditis. 61
7033979 1981
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Variations for Subacute Lymphocytic Thyroiditis

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Expression for Subacute Lymphocytic Thyroiditis

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Search GEO for disease gene expression data for Subacute Lymphocytic Thyroiditis.
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Pathways for Subacute Lymphocytic Thyroiditis

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Pathways related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
PAK Pathway 63
Show member pathways
 12.9 TCF21 IL2 FLNB FAS CD4
2
Allograft rejection 36 1
Show member pathways
 12.17 TSHR TPO TG IL2 FAS CD4
3
4-1BB Pathway 63
Show member pathways
 12.16 FAS CR2 CD4 BIRC3
4
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
11.56 SELL IL2 CD4
5
Dendritic Cells Developmental Lineage Pathway 64
11.2 SELL IL2 CD4
6
Cytokines and Inflammatory Response 1
10.87 IL2 CD4
7
IL12 signaling mediated by STAT4 1
10.82 IL2 CD4
8
Thyroxine (Thyroid Hormone) Production 1
9.58 TSHR TPO TG
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GO Terms for Subacute Lymphocytic Thyroiditis

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Biological processes related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.5 IL2 FAS CD4
2 immune response GO:0006955 9.46 IL2 FAS CR2 CD4
3 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.26 IL2 FAS
4 thyroid hormone generation GO:0006590 8.96 TPO TG
5 hormone biosynthetic process GO:0042446 8.62 TPO TG

Molecular functions related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glycosphingolipid binding GO:0043208 8.62 SELL IL2
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Sources for Subacute Lymphocytic Thyroiditis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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