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MCID: SBC005
MIFTS: 25

Subacute Lymphocytic Thyroiditis

Categories: Endocrine diseases, Immune diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Subacute Lymphocytic Thyroiditis

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MalaCards integrated aliases for Subacute Lymphocytic Thyroiditis:

Name: Subacute Lymphocytic Thyroiditis 12 15 71

Classifications:

MalaCards categories:
Anatomical: Endocrine diseases Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:7187
NCIt 49 C35829
SNOMED-CT 67 361126006
UMLS 71 C1306804
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Summaries for Subacute Lymphocytic Thyroiditis

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MalaCards based summary : Subacute Lymphocytic Thyroiditis is related to graves disease 1 and thyroid carcinoma. An important gene associated with Subacute Lymphocytic Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are Allograft rejection and 4-1BB Pathway. Affiliated tissues include thyroid, and related phenotypes are growth/size/body region and hematopoietic system

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Related Diseases for Subacute Lymphocytic Thyroiditis

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Diseases related to Subacute Lymphocytic Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 102)
# Related Disease Score Top Affiliating Genes
1 graves disease 1 30.2 TSHR TPO TG
2 thyroid carcinoma 30.2 TSHR TPO TG
3 hyperthyroidism 30.1 TSHR TPO TG
4 thyroiditis 29.8 TSHR TPO TG IL2
5 hypothyroidism 29.4 TSHR TPO TG IL2 CHD7
6 acute thyroiditis 10.5 TPO TG
7 mechanical strabismus 10.5 TPO TG
8 familial thyroid dyshormonogenesis 10.5 TPO TG
9 nonencapsulated sclerosing carcinoma 10.5 TPO TG
10 postsurgical hypothyroidism 10.5 TPO TG
11 goiter, multinodular 1, with or without sertoli-leydig cell tumors 10.5 TPO TG
12 transient congenital hypothyroidism 10.4 TSHR TPO
13 hashimoto encephalopathy 10.4 TSHR TPO
14 athyreosis 10.4 TSHR TG
15 neonatal thyrotoxicosis 10.4 TSHR TG
16 papillary thyroid microcarcinoma 10.3 TSHR TG
17 struma ovarii 10.3 TSHR TG
18 thyroid lymphoma 10.3 TPO TG PICALM
19 goiter 10.3 TSHR TPO TG
20 iodine hypothyroidism 10.3 TSHR TPO TG
21 thyroid crisis 10.3 TSHR TPO TG
22 toxic diffuse goiter 10.3 TSHR TPO TG
23 hypothyroidism, congenital, nongoitrous, 1 10.3 TSHR TG
24 endemic goiter 10.3 TSHR TPO TG
25 plummer's disease 10.3 TSHR TPO TG
26 nontoxic goiter 10.3 TSHR TPO TG
27 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.3 TSHR TPO TG
28 myxedema 10.3 TSHR TPO TG
29 subacute thyroiditis 10.3 TSHR TPO TG
30 hyperthyroxinemia 10.3 TSHR TPO TG
31 hypothyroidism, congenital, nongoitrous, 2 10.3 TSHR TPO TG
32 exophthalmos 10.3 TSHR TPO TG
33 congenital hypothyroidism 10.3 TSHR TPO TG
34 thyroid gland follicular carcinoma 10.3 TSHR TPO TG
35 differentiated thyroid carcinoma 10.2 TSHR TPO TG
36 dendritic cell thymoma 10.2 TG CD4
37 follicular adenoma 10.2 TSHR TPO TG
38 orbital disease 10.2 TSHR TG
39 papillary carcinoma 10.2 TSHR TPO TG
40 thyroid gland anaplastic carcinoma 10.2 TSHR TPO TG
41 invasive malignant thymoma 10.2 TSHR CD4
42 diabetes mellitus, insulin-dependent, 20 10.1 TPO TG
43 skin sarcoidosis 10.1 IL2 CD4
44 abacavir allergy 10.1 CYP2B6 CD4
45 superficial basal cell carcinoma 10.1 IL2 CD4
46 t-cell immunodeficiency with thymic aplasia 10.1 CHD7 CD4
47 oral tuberculosis 10.0 IL2 CD4
48 farmer's lung 10.0 IL2 CD4
49 lobomycosis 10.0 CR2 CD4
50 scleral disease 10.0 IL2 CD4

Graphical network of the top 20 diseases related to Subacute Lymphocytic Thyroiditis:



Diseases related to Subacute Lymphocytic Thyroiditis
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Symptoms & Phenotypes for Subacute Lymphocytic Thyroiditis

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MGI Mouse Phenotypes related to Subacute Lymphocytic Thyroiditis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.15 CD4 CHD7 FAS FLNB IL2 PDE10A
2 hematopoietic system MP:0005397 10.13 BIRC3 CD4 CHD7 CR2 FAS FLNB
3 homeostasis/metabolism MP:0005376 10.1 BIRC3 CD4 CHD7 CR2 FAS FLNB
4 endocrine/exocrine gland MP:0005379 10.06 CD4 CHD7 FAS IL2 TCF21 TG
5 digestive/alimentary MP:0005381 9.98 CD4 CHD7 FAS IL2 TCF21 TG
6 immune system MP:0005387 9.97 BIRC3 CD4 CHD7 CR2 FAS FLNB
7 limbs/digits/tail MP:0005371 9.43 CHD7 FAS FLNB TG TPO TSHR
8 mortality/aging MP:0010768 9.4 BIRC3 CD4 CHD7 CR2 FAS FLNB
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Drugs & Therapeutics for Subacute Lymphocytic Thyroiditis

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Search Clinical Trials , NIH Clinical Center for Subacute Lymphocytic Thyroiditis

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Genetic Tests for Subacute Lymphocytic Thyroiditis

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Anatomical Context for Subacute Lymphocytic Thyroiditis

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MalaCards organs/tissues related to Subacute Lymphocytic Thyroiditis:

40
Thyroid
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Publications for Subacute Lymphocytic Thyroiditis

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Articles related to Subacute Lymphocytic Thyroiditis:

(show all 11)
# Title Authors PMID Year
1
Painless thyroiditis associated to thyroid carcinoma: role of initial ultrasonography evaluation. 61
26421671 2016
2
Subacute lymphocytic thyroiditis after lobectomy in a patient with papillary thyroid carcinoma: a case report. 61
23286248 2013
3
Thyroiditis. 61
16734054 2006
4
[Prevalence of autoimmunological disorders of the thyroid in children in the Białystok population]. 61
17338121 2006
5
[Kikuchi's disease: a case report and literature review]. 61
12831299 2003
6
Thyroiditis: differential diagnosis and management. 61
10706157 2000
7
Clinical, laboratory, and scintigraphic manifestations of subacute and chronic thyroiditis. 61
8386991 1993
8
[Painful lymphocytic subacute thyroiditis]. 61
1552759 1992
9
The various presentations of thyroiditis. Diagnostic considerations. 61
3511814 1986
10
Thyroiditis: a clinical update. 61
3906289 1985
11
Subacute thyroiditis. 61
7033979 1981
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Variations for Subacute Lymphocytic Thyroiditis

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Expression for Subacute Lymphocytic Thyroiditis

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Search GEO for disease gene expression data for Subacute Lymphocytic Thyroiditis.
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Pathways for Subacute Lymphocytic Thyroiditis

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Pathways related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Allograft rejection 1 36
Show member pathways
 12.17 TSHR TPO TG IL2 FAS CD4
2
4-1BB Pathway 63
Show member pathways
 12.05 FAS CR2 CD4 BIRC3
3
Thyroxine (Thyroid Hormone) Production 1
9.58 TSHR TPO TG
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GO Terms for Subacute Lymphocytic Thyroiditis

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Cellular components related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.02 TSHR TPO PICALM FAS CD4

Biological processes related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thyroid hormone generation GO:0006590 9.16 TPO TG
2 hormone biosynthetic process GO:0042446 8.96 TPO TG
3 T cell differentiation GO:0030217 8.8 IL2 CHD7 CD4

Molecular functions related to Subacute Lymphocytic Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 8.8 TPO HBB CYP2B6
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Sources for Subacute Lymphocytic Thyroiditis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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