MCID: SBC007
MIFTS: 42

Subacute Thyroiditis

Categories: Endocrine diseases

Aliases & Classifications for Subacute Thyroiditis

MalaCards integrated aliases for Subacute Thyroiditis:

Name: Subacute Thyroiditis 12 37 15 73
Subacute Granulomatous Thyroiditis 12
De Quervain's Thyroiditis 12
Granulomatous Thyroiditis 12
Giant-Cell Thyroiditis 12
Thyroiditis, Subacute 44
Thyroiditis Subacute 55

Classifications:



External Ids:

Disease Ontology 12 DOID:7165
ICD10 33 E06.1
ICD9CM 35 245.1
MeSH 44 D013968
SNOMED-CT 68 38727009
KEGG 37 H01647
UMLS 73 C0040149

Summaries for Subacute Thyroiditis

MalaCards based summary : Subacute Thyroiditis, also known as subacute granulomatous thyroiditis, is related to subacute lymphocytic thyroiditis and thyroiditis. An important gene associated with Subacute Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are Allograft rejection and Aldosterone synthesis and secretion. The drugs Xylometazoline and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include thyroid, pituitary and bone, and related phenotype is immune system.

Wikipedia : 76 Subacute thyroiditis is a form of thyroiditis that can be a cause of both thyrotoxicosis and... more...

Related Diseases for Subacute Thyroiditis

Diseases in the Thyroiditis family:

Acute Thyroiditis Subacute Thyroiditis

Diseases related to Subacute Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 subacute lymphocytic thyroiditis 32.9 TG TPO
2 thyroiditis 31.1 SERPINA7 TG TPO TSHR
3 temporal arteritis 30.2 CRP IL6
4 graves' disease 30.1 SERPINA7 TG TPO TSHR
5 typhoid fever 29.7 CRP IL6
6 hypothyroidism 29.7 SERPINA7 SHBG TG TPO TSHR
7 papillary carcinoma 29.6 TG TPO TSHR
8 chlamydia 29.5 CRP IL6
9 goiter 29.5 SERPINA7 TG TPO TSHR
10 graves disease 1 29.4 SERPINA7 TG TPO TSHR
11 hashimoto thyroiditis 29.3 TG TPO TSHR
12 thyroid cancer, nonmedullary, 2 29.3 TG TPO TSHR
13 hyperthyroidism 29.3 SERPINA6 SERPINA7 SHBG TG TPO TSHR
14 dyshormonogenic goiter 10.2 SERPINA7 TG
15 thyroid crisis 10.2 SERPINA7 TG
16 suppurative thyroiditis 10.2 CRP TG
17 pulmonary aspergilloma 10.2 CRP TG
18 euthyroid sick syndrome 10.2 IL6 SERPINA7
19 cold agglutinin disease 10.2 CRP IL6
20 benign struma ovarii 10.2 TG TSHR
21 struma ovarii 10.2 TG TSHR
22 cryopyrin-associated periodic syndrome 10.2 CRP IL6
23 athyreosis 10.2 TG TSHR
24 acute cholangitis 10.2 CRP IL6
25 uremic pruritus 10.2 CRP IL6
26 postsurgical hypothyroidism 10.2 TG TSHR
27 hypoadrenalism 10.2 SHBG TG
28 neutrophilia, hereditary 10.2 CRP IL6
29 spinal disease 10.2 CRP IL6
30 viral pneumonia 10.2 CRP IL6
31 multicentric castleman disease 10.2 CRP IL6
32 castleman disease 10.2 CRP IL6
33 relapsing polychondritis 10.2 CRP IL6
34 central nervous system vasculitis 10.2 CRP IL6
35 intussusception 10.2 CRP IL6
36 louse-borne relapsing fever 10.1 CRP IL6
37 cecal disease 10.1 CRP IL6
38 pyelitis 10.1 CRP IL6
39 ischemic heart disease 10.1 CRP IL6
40 mesenteric lymphadenitis 10.1 CRP IL6
41 papillary thyroid microcarcinoma 10.1 TG TSHR
42 viral meningitis 10.1 CRP IL6
43 mycoplasma pneumoniae pneumonia 10.1 CRP IL6
44 hypersensitivity reaction type iii disease 10.1 CRP IL6
45 intermittent explosive disorder 10.1 CRP IL6
46 intermediate coronary syndrome 10.1 CRP IL6
47 exophthalmos 10.1 TG TSHR
48 systolic heart failure 10.1 CRP IL6
49 prediabetes syndrome 10.1 CRP IL6
50 acute cystitis 10.1 CRP IL6

Graphical network of the top 20 diseases related to Subacute Thyroiditis:



Diseases related to Subacute Thyroiditis

Symptoms & Phenotypes for Subacute Thyroiditis

MGI Mouse Phenotypes related to Subacute Thyroiditis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.1 CRP IL6 SERPINA6 TG TPO TSHR

Drugs & Therapeutics for Subacute Thyroiditis

Drugs for Subacute Thyroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
4 Antineoplastic Agents, Hormonal Phase 4
5 Anti-Inflammatory Agents Phase 4
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
7 Hormone Antagonists Phase 4
8 glucocorticoids Phase 4
9 Hormones Phase 4
10 Antibodies
11 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Short-term Prednisone to Treat STA Study(SPTSS) Completed NCT01837433 Phase 4 Prednisone 1 week;Prednisone 6 weeks
2 Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis Unknown status NCT02287363

Search NIH Clinical Center for Subacute Thyroiditis

Cochrane evidence based reviews: thyroiditis, subacute

Genetic Tests for Subacute Thyroiditis

Anatomical Context for Subacute Thyroiditis

MalaCards organs/tissues related to Subacute Thyroiditis:

41
Thyroid, Pituitary, Bone, T Cells, Lymph Node, Heart, Pancreas

Publications for Subacute Thyroiditis

Articles related to Subacute Thyroiditis:

(show top 50) (show all 410)
# Title Authors Year
1
Transiently Altered Distribution of F-18 FDG in a Patient with Subacute Thyroiditis. ( 29391918 )
2018
2
Subacute thyroiditis in a patient with psoriasis treated with a tumor necrosis factor-I+ inhibitor. ( 29460956 )
2018
3
Putting All the Pieces Together: Clinical, Macroscopic and Microscopic Characteristics of Subacute Thyroiditis. ( 29427032 )
2018
4
Amyloid goiter mimicking subacute thyroiditis on clinical and imaging findings: A case report. ( 29315620 )
2018
5
A Case of Thyrotoxicosis due to Simultaneous Occurrence of Subacute Thyroiditis and Graves' Disease. ( 30510812 )
2018
6
Occurrence of Subacute Thyroiditis following Influenza Vaccination. ( 30294587 )
2018
7
Sustained ventricular tachycardia caused by subacute thyroiditis. ( 30182396 )
2018
8
Prevalence of papillary thyroid cancer in subacute thyroiditis patients may be higher than it is presumed: retrospective analysis of 137 patients. ( 30210035 )
2018
9
TNF-alpha is upregulated in subacute thyroiditis and stimulates expression of miR-155-5p in thyroid follicle cells. ( 30399324 )
2018
10
Fever of Unknown Origin as a Sole Presentation of Subacute Thyroiditis in an Elderly Patient: A Case Report with Literature Review. ( 30498605 )
2018
11
18F-FDG PET/CT imaging of atypical subacute thyroiditis in thyrotoxicosis: A case report. ( 28746199 )
2017
12
Lesson of the month 1: Subacute thyroiditis: a rare cause of fever of unknown origin. ( 28148588 )
2017
13
Subacute thyroiditis causing thyrotoxic crisis; a case report with literature review. ( 28399492 )
2017
14
Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis. ( 27688010 )
2017
15
Mean Platelet Volume and Platelet Count are Elevated in Patients with Subacute Thyroiditis. ( 28879723 )
2017
16
Fine-Needle Aspiration of De Quervain's Thyroiditis (Subacute Granulomatous Thyroiditis): A Cytological Review of 20 Cases. ( 28969133 )
2017
17
Subacute Thyroiditis-An Often Overlooked Sonographic Diagnosis: Report of 3 Cases. ( 27022173 )
2016
18
Subacute thyroiditis in psoriatic arthritis treated by adalimumab. ( 27825573 )
2016
19
Subacute thyroiditis following seasonal influenza vaccination. ( 26809709 )
2016
20
Acute transverse myelitis and subacute thyroiditis associated with dengue viral infection: A case report and literature review. ( 27703498 )
2016
21
Sonographic Characteristics and Interval Changes of Subacute Thyroiditis. ( 27302899 )
2016
22
Dengue Fever Presenting Atypically with Viral Conjunctivitis and Subacute Thyroiditis. ( 27376214 )
2016
23
Increased pertechnetate and radioiodine uptake in the thyroid gland with subacute thyroiditis and concurrent Graves' disease. ( 26929941 )
2016
24
Painful thyroid nodule, a misleading presentation of subacute thyroiditis. ( 27537984 )
2016
25
Differentiating Graves' disease from subacute thyroiditis using ratio of serum free triiodothyronine to free thyroxine. ( 27570620 )
2016
26
Concurrent Onset of Subacute Thyroiditis and Gravesx^ Disease. ( 27524225 )
2016
27
Co-occurrence of subacute granulomatous thyroiditis and papillary microcarcinoma. ( 27405083 )
2016
28
Cytomegalovirus subacute thyroiditis in a patient treated by infliximab for psoriatic arthritis. ( 26184533 )
2015
29
Drug-Induced Hypersensitivity Syndrome Followed by Subacute Thyroiditis. ( 26351424 )
2015
30
A rare case showing subacute thyroiditis-like symptoms with amyloid goiter after anti-tumor necrosis factor therapy. ( 25969738 )
2015
31
A case of granulomatosis with polyangiitis preceded by subacute thyroiditis. ( 25838901 )
2015
32
Sonographic features of thyroid nodules that may help distinguish clinically atypical subacute thyroiditis from thyroid malignancy. ( 25792585 )
2015
33
Presence of Thyroid-Stimulating Hormone Receptor Antibodies in a Patient with Subacute Thyroiditis followed by Hypothyroidism and Later Graves' Disease with Ophthalmopathy: A Case Report. ( 26558237 )
2015
34
Acute hepatitis E virus infection and association with a subacute thyroiditis. ( 25536654 )
2015
35
Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis. ( 26073499 )
2015
36
Suspicious sonographic and cytological findings in patients with subacute thyroiditis: Two case reports. ( 25350937 )
2014
37
Localized subacute thyroiditis presenting as a painful hot nodule. ( 24397799 )
2014
38
Diagnosis of de quervain's subacute thyroiditis via sensor-navigated (124)Iodine PET/ultrasound ( (124)I-PET/US) fusion. ( 25060209 )
2014
39
Chinese herbal medicine for subacute thyroiditis: a systematic review of randomized controlled trials. ( 24992749 )
2014
40
Subacute thyroiditis: clinical presentation and long term outcome. ( 24803929 )
2014
41
Subacute thyroiditis metamorphosing into Gravesa89 disease. ( 24749146 )
2014
42
A novel treatment for subacute thyroiditis: administration of a mixture of lidocaine and dexamethasone using an insulin pen. ( 24943704 )
2014
43
Papillary thyroid cancer case masked by subacute thyroiditis. ( 25465609 )
2014
44
Subacute thyroiditis masquerading giant cell arteritis. ( 25174157 )
2014
45
Follow-up of a case of subacute thyroiditis with uncommon thyroid 99mTc uptake. ( 24343637 )
2013
46
Visual vignette. Subacute thyroiditis. ( 23425654 )
2013
47
Quick recovery of myocardium damage in a case of subacute thyroiditis. ( 22459018 )
2013
48
Subacute thyroiditis presenting as acute psychosis: a case report and literature review. ( 23526704 )
2013
49
Pyrexia of unknown origin--an uncommon presentation of subacute thyroiditis. ( 24003577 )
2013
50
Ultrasound findings of subacute thyroiditis: a single institution retrospective review. ( 23969266 )
2013

Variations for Subacute Thyroiditis

Expression for Subacute Thyroiditis

Search GEO for disease gene expression data for Subacute Thyroiditis.

Pathways for Subacute Thyroiditis

GO Terms for Subacute Thyroiditis

Cellular components related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 CRP IL6 SERPINA6 SERPINA7 TPO
2 extracellular region GO:0005576 9.1 CRP IL6 SERPINA6 SERPINA7 SHBG TG

Biological processes related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.16 CRP IL6
2 hormone biosynthetic process GO:0042446 8.96 TG TPO
3 negative regulation of lipid storage GO:0010888 8.62 CRP IL6

Molecular functions related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 8.62 SERPINA6 SHBG

Sources for Subacute Thyroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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