MCID: SBC007
MIFTS: 42

Subacute Thyroiditis

Categories: Endocrine diseases

Aliases & Classifications for Subacute Thyroiditis

MalaCards integrated aliases for Subacute Thyroiditis:

Name: Subacute Thyroiditis 12 38 15 17 74
Subacute Granulomatous Thyroiditis 12
De Quervain's Thyroiditis 12
Granulomatous Thyroiditis 12
Giant-Cell Thyroiditis 12
Thyroiditis, Subacute 45
Thyroiditis Subacute 56

Classifications:



External Ids:

Disease Ontology 12 DOID:7165
KEGG 38 H01647
ICD9CM 36 245.1
MeSH 45 D013968
SNOMED-CT 69 38727009
ICD10 34 E06.1
UMLS 74 C0040149

Summaries for Subacute Thyroiditis

MalaCards based summary : Subacute Thyroiditis, also known as subacute granulomatous thyroiditis, is related to subacute lymphocytic thyroiditis and thyroiditis. An important gene associated with Subacute Thyroiditis is TG (Thyroglobulin), and among its related pathways/superpathways are Allograft rejection and Aldosterone synthesis and secretion. The drugs Xylometazoline and Prednisone have been mentioned in the context of this disorder. Affiliated tissues include thyroid, bone and t cells, and related phenotype is immune system.

Wikipedia : 77 Subacute thyroiditis is a form of thyroiditis that can be a cause of both thyrotoxicosis and... more...

Related Diseases for Subacute Thyroiditis

Diseases in the Thyroiditis family:

Acute Thyroiditis Subacute Thyroiditis

Diseases related to Subacute Thyroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)
# Related Disease Score Top Affiliating Genes
1 subacute lymphocytic thyroiditis 33.0 TG TPO
2 thyroiditis 30.9 SERPINA7 TG TPO TSHR
3 thyroid crisis 30.1 SERPINA7 TG
4 graves' disease 30.0 SERPINA7 TG TPO TSHR
5 hashimoto thyroiditis 29.8 TG TPO TSHR
6 temporal arteritis 29.8 CRP IL6
7 typhoid fever 29.7 CRP IL6
8 graves disease 1 29.6 SERPINA7 TG TPO TSHR
9 goiter 29.5 SERPINA7 TG TPO TSHR
10 papillary carcinoma 29.5 TG TPO TSHR
11 chlamydia 29.4 CRP IL6
12 thyroid cancer, nonmedullary, 2 29.2 TG TPO TSHR
13 hypothyroidism 29.2 SERPINA7 SHBG TG TPO TSHR
14 hyperthyroidism 28.8 SERPINA6 SERPINA7 SHBG TG TPO TSHR
15 dyshormonogenic goiter 10.3 SERPINA7 TG
16 suppurative thyroiditis 10.3 CRP TG
17 pulmonary aspergilloma 10.3 CRP TG
18 benign struma ovarii 10.2 TG TSHR
19 struma ovarii 10.2 TG TSHR
20 athyreosis 10.2 TG TSHR
21 postsurgical hypothyroidism 10.2 TG TSHR
22 corticosteroid-binding globulin deficiency 10.2 SERPINA6 SERPINA7
23 papillary thyroid microcarcinoma 10.2 TG TSHR
24 euthyroid sick syndrome 10.2 IL6 SERPINA7
25 cold agglutinin disease 10.2 CRP IL6
26 exophthalmos 10.2 TG TSHR
27 cryopyrin-associated periodic syndrome 10.2 CRP IL6
28 acute cholangitis 10.2 CRP IL6
29 uremic pruritus 10.2 CRP IL6
30 orbital disease 10.2 CRP TSHR
31 neutrophilia, hereditary 10.2 CRP IL6
32 spinal disease 10.2 CRP IL6
33 viral pneumonia 10.2 CRP IL6
34 multicentric castleman disease 10.2 CRP IL6
35 castleman disease 10.2 CRP IL6
36 relapsing polychondritis 10.2 CRP IL6
37 central nervous system vasculitis 10.2 CRP IL6
38 intussusception 10.2 CRP IL6
39 louse-borne relapsing fever 10.2 CRP IL6
40 cecal disease 10.2 CRP IL6
41 pyelitis 10.2 CRP IL6
42 ischemic heart disease 10.2 CRP IL6
43 mesenteric lymphadenitis 10.2 CRP IL6
44 viral meningitis 10.2 CRP IL6
45 mycoplasma pneumoniae pneumonia 10.2 CRP IL6
46 hypersensitivity reaction type iii disease 10.2 CRP IL6
47 hypoadrenalism 10.2 SHBG TG
48 intermittent explosive disorder 10.2 CRP IL6
49 intermediate coronary syndrome 10.2 CRP IL6
50 systolic heart failure 10.2 CRP IL6

Graphical network of the top 20 diseases related to Subacute Thyroiditis:



Diseases related to Subacute Thyroiditis

Symptoms & Phenotypes for Subacute Thyroiditis

MGI Mouse Phenotypes related to Subacute Thyroiditis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.1 CRP IL6 SERPINA6 TG TPO TSHR

Drugs & Therapeutics for Subacute Thyroiditis

Drugs for Subacute Thyroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
2
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
3
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
4 Hormones Phase 4
5 Hormone Antagonists Phase 4
6 glucocorticoids Phase 4
7 Antineoplastic Agents, Hormonal Phase 4
8 Anti-Inflammatory Agents Phase 4
9 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
10 Immunoglobulins
11 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Short-term Prednisone to Treat STA Study(SPTSS) Completed NCT01837433 Phase 4 Prednisone 1 week;Prednisone 6 weeks
2 Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis Unknown status NCT02287363

Search NIH Clinical Center for Subacute Thyroiditis

Cochrane evidence based reviews: thyroiditis, subacute

Genetic Tests for Subacute Thyroiditis

Anatomical Context for Subacute Thyroiditis

MalaCards organs/tissues related to Subacute Thyroiditis:

42
Thyroid, Bone, T Cells, Pituitary, Lymph Node, Testes, Bone Marrow

Publications for Subacute Thyroiditis

Articles related to Subacute Thyroiditis:

(show top 50) (show all 418)
# Title Authors Year
1
Sonographic Pattern of Subacute Thyroiditis Is HLA-Dependent. ( 30728805 )
2019
2
The Risk of Recurrence of Subacute Thyroiditis Is HLA-Dependent. ( 30832406 )
2019
3
Clinical characteristics of subacute thyroiditis is different than it used to be - current state based on 15 years own material. ( 30860680 )
2019
4
Initial treatment combined with Prunella vulgaris reduced prednisolone consumption for patients with subacute thyroiditis. ( 30906749 )
2019
5
Hepcidin and Iron Homeostasis in Patients with Subacute Thyroiditis and Healthy Subjects. ( 30936776 )
2019
6
Treatment of lidocaine on subacute thyroiditis via restraining inflammatory factor expression and inhibiting pyroptosis pathway. ( 30963625 )
2019
7
Clostridium difficile colitis in the setting of subacute thyroiditis: the chicken or the egg. ( 30567894 )
2018
8
Amyloid goiter mimicking subacute thyroiditis on clinical and imaging findings: A case report. ( 29315620 )
2018
9
A Case of Thyrotoxicosis due to Simultaneous Occurrence of Subacute Thyroiditis and Graves' Disease. ( 30510812 )
2018
10
Erratum: Occurrence of Subacute Thyroiditis following Influenza Vaccination. ( 30766840 )
2018
11
Occurrence of Subacute Thyroiditis following Influenza Vaccination. ( 30294587 )
2018
12
Subacute thyroiditis in a patient with psoriasis treated with a tumor necrosis factor-α inhibitor. ( 29460956 )
2018
13
Transiently Altered Distribution of F-18 FDG in a Patient with Subacute Thyroiditis. ( 29391918 )
2018
14
Putting All the Pieces Together: Clinical, Macroscopic and Microscopic Characteristics of Subacute Thyroiditis. ( 29427032 )
2018
15
Sustained ventricular tachycardia caused by subacute thyroiditis. ( 30182396 )
2018
16
Prevalence of papillary thyroid cancer in subacute thyroiditis patients may be higher than it is presumed: retrospective analysis of 137 patients. ( 30210035 )
2018
17
TNF-alpha is upregulated in subacute thyroiditis and stimulates expression of miR-155-5p in thyroid follicle cells. ( 30399324 )
2018
18
Fever of Unknown Origin as a Sole Presentation of Subacute Thyroiditis in an Elderly Patient: A Case Report with Literature Review. ( 30498605 )
2018
19
Subacute thyroiditis in psoriatic arthritis treated by adalimumab. ( 27825573 )
2017
20
Comparison of the therapeutic effects of prednisolone and nonsteroidal anti-inflammatory drugs in patients with subacute thyroiditis. ( 27688010 )
2017
21
Lesson of the month 1: Subacute thyroiditis: a rare cause of fever of unknown origin. ( 28148588 )
2017
22
Subacute thyroiditis causing thyrotoxic crisis; a case report with literature review. ( 28399492 )
2017
23
18F-FDG PET/CT imaging of atypical subacute thyroiditis in thyrotoxicosis: A case report. ( 28746199 )
2017
24
Mean Platelet Volume and Platelet Count are Elevated in Patients with Subacute Thyroiditis. ( 28879723 )
2017
25
Fine-Needle Aspiration of De Quervain's Thyroiditis (Subacute Granulomatous Thyroiditis): A Cytological Review of 20 Cases. ( 28969133 )
2017
26
Acute transverse myelitis and subacute thyroiditis associated with dengue viral infection: A case report and literature review. ( 27703498 )
2016
27
Dengue Fever Presenting Atypically with Viral Conjunctivitis and Subacute Thyroiditis. ( 27376214 )
2016
28
Increased pertechnetate and radioiodine uptake in the thyroid gland with subacute thyroiditis and concurrent Graves' disease. ( 26929941 )
2016
29
Differentiating Graves' disease from subacute thyroiditis using ratio of serum free triiodothyronine to free thyroxine. ( 27570620 )
2016
30
Cytomegalovirus subacute thyroiditis in a patient treated by infliximab for psoriatic arthritis. ( 26184533 )
2016
31
Subacute thyroiditis following seasonal influenza vaccination. ( 26809709 )
2016
32
Subacute Thyroiditis-An Often Overlooked Sonographic Diagnosis: Report of 3 Cases. ( 27022173 )
2016
33
Sonographic Characteristics and Interval Changes of Subacute Thyroiditis. ( 27302899 )
2016
34
Concurrent Onset of Subacute Thyroiditis and Graves׳ Disease. ( 27524225 )
2016
35
Painful thyroid nodule, a misleading presentation of subacute thyroiditis. ( 27537984 )
2016
36
Cytologic Features of Subacute Granulomatous Thyroiditis Can Mimic Malignancy in Liquid-Based Preparations. ( 27167165 )
2016
37
Co-occurrence of subacute granulomatous thyroiditis and papillary microcarcinoma. ( 27405083 )
2016
38
A rare case showing subacute thyroiditis-like symptoms with amyloid goiter after anti-tumor necrosis factor therapy. ( 25969738 )
2015
39
A case of granulomatosis with polyangiitis preceded by subacute thyroiditis. ( 25838901 )
2015
40
Presence of Thyroid-Stimulating Hormone Receptor Antibodies in a Patient with Subacute Thyroiditis followed by Hypothyroidism and Later Graves' Disease with Ophthalmopathy: A Case Report. ( 26558237 )
2015
41
Acute hepatitis E virus infection and association with a subacute thyroiditis. ( 25536654 )
2015
42
Diagnosis of de quervain's subacute thyroiditis via sensor-navigated 124Iodine PET/ultrasound (124I-PET/US) fusion. ( 25060209 )
2015
43
Suspicious sonographic and cytological findings in patients with subacute thyroiditis: Two case reports. ( 25350937 )
2015
44
Sonographic features of thyroid nodules that may help distinguish clinically atypical subacute thyroiditis from thyroid malignancy. ( 25792585 )
2015
45
Prednisolone Dosing Regimen for Treatment of Subacute Thyroiditis. ( 26073499 )
2015
46
Drug-Induced Hypersensitivity Syndrome Followed by Subacute Thyroiditis. ( 26351424 )
2015
47
Subacute thyroiditis metamorphosing into Graves’ disease. ( 24749146 )
2014
48
Ultrasound findings of subacute thyroiditis: a single institution retrospective review. ( 23969266 )
2014
49
Time-lag between symptom onset and laboratory findings in patients with subacute thyroiditis. ( 24368199 )
2014
50
Localized subacute thyroiditis presenting as a painful hot nodule. ( 24397799 )
2014

Variations for Subacute Thyroiditis

Expression for Subacute Thyroiditis

Search GEO for disease gene expression data for Subacute Thyroiditis.

Pathways for Subacute Thyroiditis

GO Terms for Subacute Thyroiditis

Cellular components related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 CRP IL6 SERPINA6 SERPINA7 TPO
2 extracellular region GO:0005576 9.1 CRP IL6 SERPINA6 SERPINA7 SHBG TG

Biological processes related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.16 CRP IL6
2 hormone biosynthetic process GO:0042446 8.96 TG TPO
3 negative regulation of lipid storage GO:0010888 8.62 CRP IL6

Molecular functions related to Subacute Thyroiditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 8.62 SERPINA6 SHBG

Sources for Subacute Thyroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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