MCID: SBN001
MIFTS: 33

Subendocardial Myocardial Infarction

Categories: Cardiovascular diseases

Aliases & Classifications for Subendocardial Myocardial Infarction

MalaCards integrated aliases for Subendocardial Myocardial Infarction:

Name: Subendocardial Myocardial Infarction 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5849
NCIt 50 C35305

Summaries for Subendocardial Myocardial Infarction

MalaCards based summary : Subendocardial Myocardial Infarction is related to myocardial infarction and heart disease. An important gene associated with Subendocardial Myocardial Infarction is LDHA (Lactate Dehydrogenase A), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Degradation of the extracellular matrix. Affiliated tissues include heart, liver and spinal cord, and related phenotypes are cardiovascular system and growth/size/body region

Related Diseases for Subendocardial Myocardial Infarction

Diseases related to Subendocardial Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 myocardial infarction 30.4 F2 ICAM1 MB SERPINC1 SERPINE1
2 heart disease 29.6 F2 ICAM1 SERPINC1 SERPINE1
3 boutonneuse fever 10.2 SELE SERPINA1
4 byssinosis 10.2 A2M SERPINA1
5 congenital disorder of glycosylation, type iii 10.2 SERPINA1 SERPINC1
6 phototoxic dermatitis 10.2 ICAM1 LDHA
7 heterophyiasis 10.2 ICAM1 SELE
8 fibrinolytic defect 10.2 SERPINC1 SERPINE1
9 geniculate herpes zoster 10.2 KANTR SERPINA1
10 aspirin allergy 10.1 SERPINC1 SERPINE1
11 grange syndrome 10.1 SELE VCAM1
12 argentine hemorrhagic fever 10.1 SERPINC1 SERPINE1
13 sticky platelet syndrome 10.1 SERPINC1 SERPINE1
14 hymenolepiasis 10.1 ICAM1 SELE
15 visual agnosia 10.1 KANTR MB
16 plummer's disease 10.1 ICAM1 SELE
17 thyroid crisis 10.1 KANTR MB
18 cortical thymoma 10.1 ICAM1 VCAM1
19 exposure keratitis 10.1 KANTR SELE
20 coenurosis 10.1 F2 LDHA
21 endophthalmitis 10.1 ICAM1 SELE
22 hydrocele 10.1 ICAM1 SELE
23 intermediate coronary syndrome 10.1 MB SERPINC1
24 shwartzman phenomenon 10.1 ICAM1 VCAM1
25 mesenteric vascular occlusion 10.1 F2 MB
26 brachydactyly, type e2 10.1 ICAM1 VCAM1
27 cardiovascular organ benign neoplasm 10.1 KANTR MB
28 immune-complex glomerulonephritis 10.1 ICAM1 VCAM1
29 meningococcemia 10.1 SERPINC1 SERPINE1
30 japanese spotted fever 10.1 KANTR SERPINC1
31 benign perivascular tumor 10.1 KANTR MB
32 hypersensitivity reaction type iii disease 10.1 ICAM1 SELE
33 limbal stem cell deficiency 10.1 ICAM1 VCAM1
34 hemorrhagic fever 10.1 F2 SERPINC1
35 hepatic tuberculosis 10.1 F2 SERPINA1
36 leukocyte adhesion deficiency, type i 10.1 ICAM1 SELE
37 pulmonary immaturity 10.1 SERPINC1 VCAM1
38 spinal cord infarction 10.1 F2 SERPINC1
39 intestinal impaction 10.1 F2 SERPINC1
40 fournier gangrene 10.1 F2 SERPINC1
41 alpha-2-plasmin inhibitor deficiency 10.1 F2 SERPINC1
42 intracranial embolism 10.1 F2 SERPINC1
43 giant hemangioma 10.1 F2 SERPINC1
44 prothrombin deficiency, congenital 10.1 F2 SERPINC1
45 sagittal sinus thrombosis 10.1 F2 SERPINC1
46 legg-calve-perthes disease 10.1 SERPINC1 SERPINE1
47 sneddon syndrome 10.1 F2 SERPINC1
48 marantic endocarditis 10.1 F2 SERPINC1
49 compartment syndrome 10.1 F2 MB
50 coronary thrombosis 10.1 SERPINC1 SERPINE1

Graphical network of the top 20 diseases related to Subendocardial Myocardial Infarction:



Diseases related to Subendocardial Myocardial Infarction

Symptoms & Phenotypes for Subendocardial Myocardial Infarction

MGI Mouse Phenotypes related to Subendocardial Myocardial Infarction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 F2 ICAM1 LDHA MB SELE SERPINC1
2 growth/size/body region MP:0005378 9.76 APLP1 F2 ICAM1 LDHA MB SELE
3 hematopoietic system MP:0005397 9.56 F2 ICAM1 LDHA MB SELE SERPINC1
4 mortality/aging MP:0010768 9.28 APLP1 F2 ICAM1 LDHA MB SELE

Drugs & Therapeutics for Subendocardial Myocardial Infarction

Search Clinical Trials , NIH Clinical Center for Subendocardial Myocardial Infarction

Genetic Tests for Subendocardial Myocardial Infarction

Anatomical Context for Subendocardial Myocardial Infarction

MalaCards organs/tissues related to Subendocardial Myocardial Infarction:

41
Heart, Liver, Spinal Cord, Thyroid

Publications for Subendocardial Myocardial Infarction

Articles related to Subendocardial Myocardial Infarction:

(show all 16)
# Title Authors Year
1
Negative pressure pulmonary edema following septoplasty surgery triggering acute subendocardial myocardial infarction. ( 25104982 )
2014
2
MultiContrast Delayed Enhancement (MCODE) improves detection of subendocardial myocardial infarction by late gadolinium enhancement cardiovascular magnetic resonance: a clinical validation study. ( 23199362 )
2012
3
Dual SPECT imaging with Tc-99m pyrophosphate and Tl-201 of circumferential subendocardial myocardial infarction in aortic stenosis without coronary artery stenosis. ( 18496451 )
2008
4
Prompt use of integrilin (eptifibatide) for unstable angina/subendocardial myocardial infarction: abrupt resolution of chest discomfort marked by brief reperfusion arrhythmias and subsequent stabilization. ( 11156712 )
2000
5
Early temporal expression of soluble cellular adhesion molecules in patients with unstable angina and subendocardial myocardial infarction. ( 10215296 )
1999
6
Apical hypertrophic cardiomyopathy presenting as acute subendocardial myocardial infarction. ( 8463017 )
1993
7
Coronary heart disease in residents of Rochester, Minnesota. VI. Hospital and posthospital course of patients with transmural and subendocardial myocardial infarction. ( 3999808 )
1985
8
Subendocardial myocardial infarction. ( 6953958 )
1982
9
Subendocardial myocardial infarction. ( 7046441 )
1982
10
Subendocardial myocardial infarction: a follow-up study of 55 cases. ( 7274267 )
1981
11
Acute subendocardial myocardial infarction: its detection by Tc-99m stannous pyrophosphate myocardial scintigraphy. ( 7371345 )
1980
12
Technetium-99m stannous pyrophosphate myocardial scintigraphy in the recognition of acute subendocardial myocardial infarction. ( 882934 )
1977
13
Acute subendocardial myocardial infarction in patients. Its detection by Technetium 99-m stannous pyrophosphate myocardial scintigrams. ( 166768 )
1975
14
Acute circular subendocardial myocardial infarction of the left ventricle of the heart. A clinico-pathological study of 12 cases. ( 4830520 )
1974
15
Subendocardial myocardial infarction. ( 13819375 )
1960
16
Subendocardial myocardial infarction with special reference to the electrocardiographic changes. ( 15419148 )
1950

Variations for Subendocardial Myocardial Infarction

Expression for Subendocardial Myocardial Infarction

Search GEO for disease gene expression data for Subendocardial Myocardial Infarction.

Pathways for Subendocardial Myocardial Infarction

Pathways related to Subendocardial Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.99 A2M F2 SELE SERPINA1 SERPINC1 SERPINE1
2
Show member pathways
12.49 A2M ICAM1 SERPINE1 VCAM1
3
Show member pathways
12.07 F2 ICAM1 SERPINE1
4 11.86 ICAM1 SELE VCAM1
5 11.83 ICAM1 SELE VCAM1
6
Show member pathways
11.76 A2M F2 SERPINC1 SERPINE1
7 11.74 ICAM1 SERPINE1 VCAM1
8 11.67 ICAM1 SELE VCAM1
9
Show member pathways
11.38 ICAM1 SELE VCAM1
10 11.25 ICAM1 SELE SERPINE1 VCAM1
11 11.23 ICAM1 SELE VCAM1
12 11.16 A2M F2 SERPINA1 SERPINC1 SERPINE1
13 11.15 ICAM1 SELE VCAM1
14 11.14 LDHA SERPINE1
15 10.95 F2 ICAM1
16 10.88 ICAM1 SELE VCAM1
17 10.7 ICAM1 VCAM1

GO Terms for Subendocardial Myocardial Infarction

Cellular components related to Subendocardial Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 A2M F2 ICAM1 SELE SERPINA1 SERPINC1
2 blood microparticle GO:0072562 9.5 A2M F2 SERPINC1
3 platelet alpha granule lumen GO:0031093 9.43 A2M SERPINA1 SERPINE1
4 collagen-containing extracellular matrix GO:0062023 9.35 A2M ICAM1 SERPINA1 SERPINC1 SERPINE1
5 extracellular exosome GO:0070062 9.28 A2M F2 ICAM1 LDHA MB SERPINA1

Biological processes related to Subendocardial Myocardial Infarction according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.78 F2 SERPINA1 SERPINC1
2 extracellular matrix organization GO:0030198 9.77 ICAM1 SERPINE1 VCAM1
3 blood coagulation GO:0007596 9.75 F2 SERPINA1 SERPINC1
4 response to lipopolysaccharide GO:0032496 9.74 ICAM1 SELE VCAM1
5 platelet degranulation GO:0002576 9.7 A2M SERPINA1 SERPINE1
6 response to nutrient GO:0007584 9.63 LDHA SERPINC1 VCAM1
7 acute-phase response GO:0006953 9.61 F2 SERPINA1
8 negative regulation of endothelial cell apoptotic process GO:2000352 9.6 ICAM1 SERPINE1
9 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 9.58 ICAM1 SERPINE1
10 fibrinolysis GO:0042730 9.56 F2 SERPINE1
11 response to hypoxia GO:0001666 9.56 ICAM1 LDHA MB VCAM1
12 leukocyte tethering or rolling GO:0050901 9.55 SELE VCAM1
13 blood coagulation, intrinsic pathway GO:0007597 9.54 A2M F2
14 hemostasis GO:0007599 9.54 F2 SERPINA1 SERPINC1
15 positive regulation of blood coagulation GO:0030194 9.51 F2 SERPINE1
16 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.5 ICAM1 SELE VCAM1
17 regulation of blood coagulation GO:0030193 9.49 F2 SERPINC1
18 negative regulation of fibrinolysis GO:0051918 9.48 F2 SERPINE1
19 negative regulation of endopeptidase activity GO:0010951 9.46 A2M SERPINA1 SERPINC1 SERPINE1
20 acute inflammatory response to antigenic stimulus GO:0002438 9.43 ICAM1 SERPINC1
21 membrane to membrane docking GO:0022614 9.4 ICAM1 VCAM1
22 leukocyte cell-cell adhesion GO:0007159 9.13 ICAM1 SELE VCAM1
23 negative regulation of peptidase activity GO:0010466 8.92 A2M SERPINA1 SERPINC1 SERPINE1

Molecular functions related to Subendocardial Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.46 A2M SERPINA1 SERPINC1 SERPINE1
2 heparin binding GO:0008201 9.43 APLP1 F2 SERPINC1
3 protease binding GO:0002020 9.26 A2M SERPINA1 SERPINC1 SERPINE1
4 serine-type endopeptidase inhibitor activity GO:0004867 8.92 A2M SERPINA1 SERPINC1 SERPINE1

Sources for Subendocardial Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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