MCID: SBG006
MIFTS: 28

Subglottis Benign Neoplasm

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Subglottis Benign Neoplasm

MalaCards integrated aliases for Subglottis Benign Neoplasm:

Name: Subglottis Benign Neoplasm 12
Neoplasm of Subglottis 70
Subglottis Neoplasm 15
Subglottic Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10069
NCIt 50 C4426
SNOMED-CT 67 126696001
UMLS 70 C0345746

Summaries for Subglottis Benign Neoplasm

Disease Ontology : 12 A laryngeal benign neoplasm that is located in the subglottic area of the larynx.

MalaCards based summary : Subglottis Benign Neoplasm, also known as neoplasm of subglottis, is related to epiglottis cancer and supraglottis neoplasm. An important gene associated with Subglottis Benign Neoplasm is PDPN (Podoplanin), and among its related pathways/superpathways are NF-kappaB Signaling and Antigen activates B Cell Receptor (BCR) leading to generation of second messengers. Affiliated tissues include subglottic area of the larynx and trachea, and related phenotypes are hematopoietic system and behavior/neurological

Related Diseases for Subglottis Benign Neoplasm

Diseases related to Subglottis Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 epiglottis cancer 10.4 PDPN CAGE1
2 supraglottis neoplasm 10.4 PDPN CAGE1
3 atypical neurofibroma 10.3 PDPN NF1
4 dacryocystocele 10.3 PDPN NF1
5 chronic inflammation of lacrimal passage 10.3 PDPN NF1
6 bladder lymphoma 10.2 SPN CD79A
7 lung lymphoma 10.2 SPN CD79A
8 infected hydrocele 10.2 SPN CD79A
9 bone lymphoma 10.2 SPN CD79A
10 breast lymphoma 10.2 SPN CD79A
11 gastrointestinal lymphoma 10.2 SPN CD79A
12 patella, chondromalacia of 10.1 CD79A CAGE1
13 breast osteosarcoma 10.1 SPN CD79A
14 basidiobolomycosis 10.1 KHK IL10
15 laryngeal benign neoplasm 10.1 PDPN CAGE1
16 gallbladder lymphoma 10.1 SPN CD79A
17 discoid lupus erythematosus 10.1 PDPN IL10
18 cardiovascular organ benign neoplasm 10.0 SDHB PDPN NF1
19 composite lymphoma 10.0 CD79A CD22
20 neural crest tumor 10.0 SDHC SDHB
21 chronic graft versus host disease 10.0 IL10 CD79A
22 gastric leiomyosarcoma 10.0 SDHC SDHB
23 paragangliomas 1 10.0 SDHC SDHB
24 intraocular retinoblastoma 10.0 SYK CAGE1
25 eye lymphoma 10.0 IL10 CD22
26 orofacial granulomatosis 10.0 IL10 CD79A
27 gallbladder disease 10.0 PDPN MIR29C IL10
28 dacryoadenitis 10.0 RAB3D IL10
29 cerebellar angioblastoma 10.0 SDHC SDHB
30 pheochromocytoma-paraganglioma 10.0 SDHC SDHB
31 alpha chain disease 10.0 SPN CD79A CD22
32 spleen cancer 10.0 SPN CD79A CD22
33 cll/sll 10.0 SPN CD79A CD22
34 marginal zone b-cell lymphoma 10.0 SPN CD79A CD22
35 carney triad 9.9 SDHC SDHB PDPN
36 mature b-cell neoplasm 9.9 SPN CD79A CD22
37 sporotrichosis 9.9 IL10 CD79A
38 elephantiasis 9.9 NF1 IL10
39 baylisascariasis 9.9 IL10 CD79A
40 lymphoma, mucosa-associated lymphoid type 9.9 SPN CD79A CD22
41 extra-adrenal pheochromocytoma 9.9 SDHC SDHB NF1
42 esophagus leiomyoma 9.9 SDHC SDHB NF1
43 adrenal medulla cancer 9.9 SDHC SDHB NF1
44 chondroma 9.9 SDHC SDHB NF1
45 paraganglioma and gastric stromal sarcoma 9.9 SDHC SDHB NF1
46 paraganglioma 9.9 SDHC SDHB NF1
47 multiple endocrine neoplasia, type i 9.9 SDHC SDHB NF1
48 multiple endocrine neoplasia, type iia 9.9 SDHC SDHB NF1
49 multiple endocrine neoplasia 9.9 SDHC SDHB NF1
50 hereditary paraganglioma-pheochromocytoma syndromes 9.9 SDHC SDHB NF1

Graphical network of the top 20 diseases related to Subglottis Benign Neoplasm:



Diseases related to Subglottis Benign Neoplasm

Symptoms & Phenotypes for Subglottis Benign Neoplasm

MGI Mouse Phenotypes related to Subglottis Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.15 CD22 CD79A IL10 NF1 PDPN SDHB
2 behavior/neurological MP:0005386 10.14 IL10 NF1 PDPN RAB3D SDHB SDHC
3 homeostasis/metabolism MP:0005376 10.13 CD79A IL10 KHK NF1 NFIB PDPN
4 immune system MP:0005387 10 CD22 CD79A IL10 NF1 PDPN SDHB
5 mortality/aging MP:0010768 9.97 CD22 CD79A IL10 NF1 NFIB PDPN
6 neoplasm MP:0002006 9.5 CD79A IL10 NF1 SDHB SDHC SPN
7 respiratory system MP:0005388 9.17 IL10 NF1 NFIB PDPN RAB3D STAT3

Drugs & Therapeutics for Subglottis Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Subglottis Benign Neoplasm

Genetic Tests for Subglottis Benign Neoplasm

Anatomical Context for Subglottis Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Subglottis Benign Neoplasm:

19
Subglottic Area Of The Larynx

MalaCards organs/tissues related to Subglottis Benign Neoplasm:

40
Trachea

Publications for Subglottis Benign Neoplasm

Articles related to Subglottis Benign Neoplasm:

(show all 20)
# Title Authors PMID Year
1
Difficult Airway Due to an Undiagnosed Subglottic Tumor: A Case Report. 61
27082606 2016
2
[Laryngeal function as node metastasis predictor in patients with cancer of the larynx]. 61
20957813 2010
3
Rosai-Dorfman disease of the subglottis diagnosed by ultrasound-guided fine-needle aspiration biopsy: a case report. 61
19953629 2010
4
A subglottic mass mimicking near-fatal asthma: a challenge of diagnosis. 61
14751479 2004
5
Subglottic leiomyoma: report of a case. 61
12517061 2002
6
[Subglottic MALT-type lymphoma: unusual location]. 61
12584885 2002
7
[Recurrence of peritracheostoma and emergency tracheotomy]. 61
9376140 1997
8
Radical radiotherapy for T3 laryngeal cancers. 61
8765344 1996
9
[Anesthetic management of Nd-YAG laser surgery in the airway using a larengeal mask]. 61
8583667 1995
10
Pediatric laryngeal granular cell tumor. 61
1494192 1992
11
Laser surgery for the treatment of larynx carcinomas: indications, techniques, and preliminary results. 61
1739255 1992
12
Inflammatory pseudotumor of the subglottis. 61
1567612 1992
13
Primary radiotherapy of T1 squamous cell carcinoma of the larynx: analysis of 478 patients treated from 1963 to 1985. 61
2370181 1990
14
[Preliminary results of endolaryngeal laser resections of laryngeal cancers]. 61
2373645 1990
15
The neck after vertical hemilaryngectomy: computed tomographic study. 61
6718727 1984
16
Granular cell tumor of the larynx in a 5-year-old child. 61
6703597 1984
17
Cancer of the glottis: prognostic factors in radiation therapy. 61
6611940 1983
18
Peristomal recurrence: pathophysiology, prevention, treatment. 61
7443239 1980
19
Adenoid cystic carcinoma (cylindroma) of the trachea masquerading as asthma. 61
171462 1975
20
Indications for transconioscopy. 61
1192283 1975

Variations for Subglottis Benign Neoplasm

Expression for Subglottis Benign Neoplasm

Search GEO for disease gene expression data for Subglottis Benign Neoplasm.

Pathways for Subglottis Benign Neoplasm

GO Terms for Subglottis Benign Neoplasm

Cellular components related to Subglottis Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell receptor complex GO:0019815 9.16 SYK CD79A
2 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.96 SDHC SDHB
3 respiratory chain complex II GO:0045273 8.62 SDHC SDHB

Biological processes related to Subglottis Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of tumor necrosis factor production GO:0032760 9.13 SYK STAT3 SPN
2 negative regulation of cell proliferation GO:0008285 9.1 STAT3 PDPN NFIB NF1 MIR29C IL10

Sources for Subglottis Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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