MCID: SBL003
MIFTS: 30

Subleukemic Leukemia

Categories: Blood diseases, Cancer diseases, Rare diseases

Aliases & Classifications for Subleukemic Leukemia

MalaCards integrated aliases for Subleukemic Leukemia:

Name: Subleukemic Leukemia 12 15
Aleukemic Leukemia Cutis 52 71
Leukemia Subleukemic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:12965
UMLS 71 C0887846

Summaries for Subleukemic Leukemia

Disease Ontology : 12 A leukemia that is characterized by the presence of abnormal white blood cells located in peripheral blood, but in which the total number of white blood cells is normal.

MalaCards based summary : Subleukemic Leukemia, also known as aleukemic leukemia cutis, is related to aleukemic leukemia cutis and lymphocytic leukemia. An important gene associated with Subleukemic Leukemia is MPO (Myeloperoxidase), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include peripheral blood, monocytes and myeloid.

Related Diseases for Subleukemic Leukemia

Diseases related to Subleukemic Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 aleukemic leukemia cutis 12.8
2 lymphocytic leukemia 10.6
3 leukemia, acute lymphoblastic 10.6
4 myeloid leukemia 10.5
5 acute monoblastic leukemia 10.5
6 alveoli adenoma 10.5 SFTPC SCGB1A1
7 leukemia, acute monocytic 10.5
8 monocytic leukemia 10.5
9 primary hepatic neuroendocrine carcinoma 10.5 SYP S100B
10 hypoganglionosis 10.5 SYP S100B
11 cerebral primitive neuroectodermal tumor 10.5 SYP S100B
12 tanycytic ependymoma 10.5 SYP OLIG2
13 rosette-forming glioneuronal tumor 10.5 SYP S100B
14 glomangiosarcoma 10.5 SYP MLANA
15 angiocentric glioma 10.5 SYP S100B
16 anti-basement membrane glomerulonephritis 10.5 MPO EDA
17 ovarian cystic teratoma 10.5 SYP MLANA
18 sarcomatoid transitional cell carcinoma 10.5 SYP MLANA
19 leukemia, acute myeloid 10.5
20 benign perivascular tumor 10.5 SYP MLANA
21 bronchial neoplasm 10.4 SFTPC SCGB1A1
22 melanoma in congenital melanocytic nevus 10.4 S100B MLANA
23 lentigo maligna melanoma 10.4 S100B MLANA
24 papillary adenoma 10.4 SYP SFTPC SCGB1A1
25 ectopic cushing syndrome 10.4 SYP S100B
26 cellular ependymoma 10.4 SYP OLIG2
27 spinal cord melanoma 10.4 OLIG2 MLANA
28 laryngeal small cell carcinoma 10.4 SYP MLANA
29 anaplastic ependymoma 10.4 SYP S100B
30 chordoid meningioma 10.4 SYP S100B
31 acute leukemia 10.4
32 medullomyoblastoma 10.4 SYP MB
33 epithelioid malignant peripheral nerve sheath tumor 10.4 S100B MLANA
34 dendritic cell tumor 10.4 S100B MPO CR2
35 lung clear cell carcinoma 10.4 SYP MB
36 malignant triton tumor 10.4 S100B MB
37 malignant melanocytic neoplasm of the peripheral nerve sheath 10.3 SYP ENO2
38 ureter small cell carcinoma 10.3 SYP ENO2
39 dysembryoplastic neuroepithelial tumor 10.3 SYP S100B OLIG2
40 anal neuroendocrine tumor 10.3 SYP ENO2
41 rosai-dorfman disease 10.3 S100B CR2
42 sinonasal undifferentiated carcinoma 10.3 SYP ENO2
43 cerebral neuroblastoma 10.3 SYP ENO2
44 juvenile pilocytic astrocytoma 10.3 SYP S100B OLIG2
45 papillary tumor of the pineal region 10.3 SYP ENO2
46 small cell carcinoma of the bladder 10.3 SYP ENO2
47 urinary bladder small cell neuroendocrine carcinoma 10.3 SYP ENO2
48 intracranial primitive neuroectodermal tumor 10.3 SYP ENO2
49 bile duct mucinous adenocarcinoma 10.3 SYP ENO2
50 nodular prostate 10.3 SYP ENO2

Graphical network of the top 20 diseases related to Subleukemic Leukemia:



Diseases related to Subleukemic Leukemia

Symptoms & Phenotypes for Subleukemic Leukemia

Drugs & Therapeutics for Subleukemic Leukemia

Search Clinical Trials , NIH Clinical Center for Subleukemic Leukemia

Genetic Tests for Subleukemic Leukemia

Anatomical Context for Subleukemic Leukemia

The Foundational Model of Anatomy Ontology organs/tissues related to Subleukemic Leukemia:

19
Peripheral Blood

MalaCards organs/tissues related to Subleukemic Leukemia:

40
Monocytes, Myeloid, Skin, T Cells, B Cells, Bone, Neutrophil

Publications for Subleukemic Leukemia

Articles related to Subleukemic Leukemia:

(show top 50) (show all 52)
# Title Authors PMID Year
1
Chronic lymphopenia and neutropenia in a dog with large granular lymphocytic leukemia. 61
31808187 2019
2
Aleukemic leukemia cutis mimicking urticaria pigmentosa in a patient of T-cell acute lymphoblastic leukemia. 61
31397398 2019
3
In reply: Aleukemic leukemia cutis. 61
31066672 2019
4
To the Editor: Aleukemic leukemia cutis. 61
31066671 2019
5
Aleukemic leukemia cutis. 61
30742583 2019
6
Ominous cutaneous presentation of acute myeloid leukemia without peripheral blood involvement upon initial presentation and relapse: case report and literature review. 61
30698150 2018
7
Myeloid Neoplasms. 61
28802501 2017
8
Aleukemic Myeloid Leukemia Cutis with a Kikuchi Disease-Like Inflammatory Pattern in Myelodysplastic Syndrome. 61
28376531 2017
9
Aleukemic Leukemia Cutis Presenting as a Sole Sign of Relapsed Paediatric Acute Lymphoblastic Leukemia. 61
27408353 2016
10
Bilateral Aleukemic Myeloid Sarcoma of the Eyelids With Indolent Course. 61
26863061 2016
11
Pediatric aleukemic leukemia cutis: report of 3 cases and review of the literature. 61
25148106 2015
12
Acute myeloid leukemia 7 years after aleukemic leukemia cutis. 61
24261792 2015
13
Sweet syndrome-like neutrophilic infiltrate as initial presentation of acute myelogenous leukemia. 61
23538898 2014
14
Aleukemic leukemia cutis: an unusual rash in a child. 61
25035690 2014
15
Recurrent aleukemic leukemia cutis in a patient with pre-B-cell acute lymphoblastic leukemia. 61
23733764 2013
16
Acute promyelocytic leukemia following aleukemic leukemia cutis harboring NPM/RARA fusion gene. 61
22573339 2012
17
Aleukemic leukemia cutis manifesting with disseminated nodular eruptions and a plaque preceding acute monocytic leukemia: a case report. 61
22187541 2011
18
Aleukemic leukemia cutis in a child preceding T-cell acute lymphoblastic leukemia. 61
21895759 2011
19
Siblings presenting with progressive congenital aleukemic leukemia cutis. 61
21425444 2011
20
Aleukemic leukemia cutis with extensive bone involvement. 61
20708479 2010
21
Spontaneous regression of aleukemic leukemia cutis harboring a NPM/RARA fusion gene in an infant with cutaneous mastocytosis. 61
19052694 2009
22
Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report. 61
18782972 2008
23
Aleukemic leukemia cutis. 61
17456918 2007
24
[Recurrent spontaneous regression of aleukemic leukemia cutis in a girl with acute monocytic leukemia]. 61
16986716 2006
25
[Agranular CD4+/CD56+ haematodermic neoplasm (Precursor haematologic neoplasm)]. 61
16161251 2005
26
Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. 61
15540904 2004
27
Therapy-related leukemia cutis: case study of an aggressive disorder. 61
12920571 2003
28
Chronic lower limb ulcer? No--chloroma! 61
15866842 2003
29
[Aleukemic monoblastic leukemia cutis]. 61
14576608 2003
30
Primary aleukemic myeloid leukemia cutis treated successfully with combination chemotherapy: report of a case and review of the literature. 61
12768324 2003
31
Aleukemic monocytic leukemia cutis. 61
12080951 2002
32
Guess what. B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis. 61
11275816 2001
33
Aleukemic leukemia cutis presenting as benign-appearing exanthema. 61
11411915 2001
34
Monocytic aleukemic leukemia cutis. 61
10565632 1999
35
Cutaneous granulocytic sarcoma mimicking immunoblastic large cell lymphoma. 61
10365856 1999
36
Aleukemic leukemia cutis in an adolescent boy. 61
10084909 1999
37
"Aleukemic" granulomatous leukemia cutis. 61
9700385 1998
38
[Monocytic aleukemic leukemia cutis]. 61
9676121 1998
39
Aleukemic leukemia cutis in a patient with acute lymphoblastic leukemia. 61
9555803 1998
40
Aleukemic "leukemia cutis" of monocytic lineage. 61
9146562 1997
41
Aleukemic leukemia cutis preceding overt acute myeloid leukemia in myelodysplastic syndrome. 61
8980276 1997
42
Lymphocytic aleukemic leukemia cutis. 61
8912603 1996
43
Aleukemic monocytic leukemia cutis. 61
8577191 1996
44
Skin involvement in myelogenous leukemia: morphologic and immunophenotypic heterogeneity of skin infiltrates. 61
7824512 1994
45
Acute myelomonocytic leukemia presenting as a benign-appearing cutaneous eruption. 61
2334186 1990
46
Aleukemic leukemia cutis. 61
2406302 1990
47
[Monocytic aleukemic leukemia cutis]. 61
3070080 1988
48
Aleukemic leukemia cutis. 61
3729513 1986
49
Aleukemic leukemia cutis. An unusual presentation of acute myelomonocytic leukemia. 61
2943614 1986
50
Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions. 61
6579062 1983

Variations for Subleukemic Leukemia

Expression for Subleukemic Leukemia

Search GEO for disease gene expression data for Subleukemic Leukemia.

Pathways for Subleukemic Leukemia

Pathways related to Subleukemic Leukemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 SYP S100B RBFOX3 ENO2 AVP
2 11.23 SYP S100B OLIG2
3 10.86 TNFRSF8 CR2 CD24

GO Terms for Subleukemic Leukemia

Cellular components related to Subleukemic Leukemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 SFTPC SCGB1A1 S100B PTHLH OXT MPO
2 perikaryon GO:0043204 9.26 RBFOX3 GLUL ENO2 AIF1
3 secretory granule GO:0030141 8.92 SCGB1A1 OXT MPO AVP

Biological processes related to Subleukemic Leukemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 9.5 SCGB1A1 PTHLH OXT
2 grooming behavior GO:0007625 9.37 OXT AVP
3 maternal behavior GO:0042711 9.26 OXT AVP
4 hyperosmotic salinity response GO:0042538 9.16 OXT AVP
5 maternal aggressive behavior GO:0002125 8.96 OXT AVP
6 response to glucocorticoid GO:0051384 8.92 SCGB1A1 S100B OXT AIF1

Molecular functions related to Subleukemic Leukemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 PTHLH OXT AVP
2 neurohypophyseal hormone activity GO:0005185 8.62 OXT AVP

Sources for Subleukemic Leukemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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