MCID: SBM004
MIFTS: 22

Submandibular Gland Cancer

Categories: Cancer diseases, Oral diseases, Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Submandibular Gland Cancer

MalaCards integrated aliases for Submandibular Gland Cancer:

Name: Submandibular Gland Cancer 12 15
Malignant Tumor of the Submandibular Gland 12
Malignant Neoplasm of Submaxillary Gland 12
Malignant Tumor of Submandibular Gland 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9173
ICD10 33 C08.0
ICD9CM 35 142.1
NCIt 50 C3526
SNOMED-CT 68 363380002 94077005
UMLS 73 C0153360

Summaries for Submandibular Gland Cancer

MalaCards based summary : Submandibular Gland Cancer, also known as malignant tumor of the submandibular gland, is related to prostate cancer and prostatitis. An important gene associated with Submandibular Gland Cancer is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. Affiliated tissues include prostate and bone, and related phenotype is Increased cell death HMECs cells.

Related Diseases for Submandibular Gland Cancer

Diseases related to Submandibular Gland Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 prostate cancer 9.8
2 prostatitis 9.8
3 atrophy of prostate 9.6 KLK3 TP53
4 prostate squamous cell carcinoma 9.6 KLK3 TP53
5 clear cell adenocarcinoma 9.6 KLK3 TP53
6 female breast cancer 9.6 KLK3 TP53
7 small cell carcinoma 9.6 KLK3 TP53
8 suppression of tumorigenicity 12 9.5 KLK3 TP53
9 male reproductive organ cancer 9.5 KLK3 TP53
10 breast disease 9.4 KLK3 TP53
11 cell type cancer 9.3 KLK3 TP53
12 bladder urothelial carcinoma 9.2 KLK3 TP53
13 adamantinoma of long bones 9.0 KLK3 TP53

Graphical network of the top 20 diseases related to Submandibular Gland Cancer:



Diseases related to Submandibular Gland Cancer

Symptoms & Phenotypes for Submandibular Gland Cancer

GenomeRNAi Phenotypes related to Submandibular Gland Cancer according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death HMECs cells GR00103-A-0 8.62 KLK3 TP53

Drugs & Therapeutics for Submandibular Gland Cancer

Search Clinical Trials , NIH Clinical Center for Submandibular Gland Cancer

Genetic Tests for Submandibular Gland Cancer

Anatomical Context for Submandibular Gland Cancer

MalaCards organs/tissues related to Submandibular Gland Cancer:

41
Prostate, Bone

Publications for Submandibular Gland Cancer

Articles related to Submandibular Gland Cancer:

# Title Authors Year
1
Submandibular gland cancer: Specific features and treatment considerations. ( 29083518 )
2018
2
Nodal Stage: Is It a Prognostic Factor for Submandibular Gland Cancer? ( 29227792 )
2017
3
A Case of Advanced Submandibular Gland Cancer in Which Increased Prostate-Specific Antigen and Multiple Bone Metastases Wrongly Suggested Concurrent Prostate Cancer. ( 29430238 )
2017
4
Robotic-assisted neck dissection in submandibular gland cancer: preliminary report. ( 23597950 )
2013
5
Prognostic factors and outcome analysis of submandibular gland cancer: a clinical audit. ( 20538399 )
2010
6
In vitro metabolism of estrone 2,4,6,7-3H and 4-androstene-3,17-dione-1,2-3H in submandibular gland and submandibular gland cancer tumor. ( 4421580 )
1974

Variations for Submandibular Gland Cancer

Expression for Submandibular Gland Cancer

Search GEO for disease gene expression data for Submandibular Gland Cancer.

Pathways for Submandibular Gland Cancer

Pathways related to Submandibular Gland Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.7 KLK3 TP53
2 11.34 KLK3 TP53

GO Terms for Submandibular Gland Cancer

Cellular components related to Submandibular Gland Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-containing complex GO:0032991 8.62 KLK3 TP53

Sources for Submandibular Gland Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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