Subserous Uterine Fibroid disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Subserous Uterine Fibroid

MalaCards integrated aliases for Subserous Uterine Fibroid:

Name: Subserous Uterine Fibroid ¹² ¹⁵

Subserous Leiomyoma of Uterus ¹² ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Neoplasms

Benign neoplasms

Leiomyoma of uterus

Subserosal leiomyoma of uterus

External Ids:

Disease Ontology ¹² DOID:13560

ICD9CM ³⁴ 218.2

SNOMED-CT ⁶⁷ 95280005

ICD10 ³² D25.2

UMLS ⁷¹ C0153995

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Summaries for Subserous Uterine Fibroid

Disease Ontology : ¹² An uterine fibroid that is located adjacent to the outside of the uterus.

MalaCards based summary : Subserous Uterine Fibroid, also known as subserous leiomyoma of uterus, is related to leiomyoma and myofibroma. An important gene associated with Subserous Uterine Fibroid is HPSE2 (Heparanase 2 (Inactive)), and among its related pathways/superpathways is Ovarian Infertility Genes. Affiliated tissues include uterus, and related phenotype is reproductive system.

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Related Diseases for Subserous Uterine Fibroid

Diseases related to Subserous Uterine Fibroid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)

#	Related Disease	Score	Top Affiliating Genes
1	leiomyoma	30.1	PGR CYP19A1
2	myofibroma	10.3
3	pemphigus	10.3
4	pemphigus foliaceus	10.3
5	adhesions of uterus	10.0	PGR AMH
6	sex cord-gonadal stromal tumor	10.0	PGR AMH
7	endometritis	9.9	PGR OXT
8	benign metastasizing leiomyoma	9.8	PGR CYP19A1
9	postmenopausal atrophic vaginitis	9.8	CYP19A1 AMH
10	mammographic density	9.8	PGR CYP19A1
11	ovarian endometrioid stromal sarcoma	9.8	PGR CYP19A1
12	juvenile nasopharyngeal angiofibroma	9.8	PGR CYP19A1
13	gender identity disorder	9.8	PGR CYP19A1
14	progesterone-receptor positive breast cancer	9.8	PGR CYP19A1
15	estrogen excess	9.8	PGR CYP19A1
16	hypertrophy of breast	9.8	PGR CYP19A1
17	premature menopause	9.8	CYP19A1 AMH
18	steroid inherited metabolic disorder	9.8	CYP19A1 AMH
19	lobular neoplasia	9.8	PGR CYP19A1
20	46,xy sex reversal 2	9.8	CYP19A1 AMH
21	46,xy sex reversal	9.8	CYP19A1 AMH
22	prostatic hypertrophy	9.8	PGR CYP19A1
23	ovarian cyst	9.7	CYP19A1 AMH
24	sertoli cell tumor	9.7	PGR CYP19A1
25	luminal breast carcinoma a	9.7	PGR CYP19A1
26	amelogenesis imperfecta, type ig	9.7	PGR CYP19A1
27	ovarian hyperstimulation syndrome	9.7	CYP19A1 AMH
28	anovulation	9.7	CYP19A1 AMH
29	hypoactive sexual desire disorder	9.7	OXT CYP19A1
30	vaginal adenoma	9.7	OXT CYP19A1
31	breast fibroadenoma	9.7	PGR CYP19A1
32	vaginal benign neoplasm	9.7	OXT CYP19A1
33	estrogen-receptor negative breast cancer	9.7	PGR CYP19A1
34	primary pigmented nodular adrenocortical disease	9.7	PGR CYP19A1
35	premature ejaculation	9.7	OXT CYP19A1
36	teeth hard tissue disease	9.7	PGR CYP19A1
37	gynecomastia	9.7	PGR CYP19A1
38	female breast cancer	9.7	PGR CYP19A1
39	mccune-albright syndrome	9.7	CYP19A1 AMH
40	pseudohermaphroditism	9.7	CYP19A1 AMH
41	pre-malignant neoplasm	9.7	PGR CYP19A1
42	disorders of sexual development	9.6	CYP19A1 AMH
43	lipoid congenital adrenal hyperplasia	9.6	CYP19A1 AMH
44	sporadic breast cancer	9.6	PGR CYP19A1
45	in situ carcinoma	9.6	PGR CYP19A1
46	estrogen-receptor positive breast cancer	9.6	PGR CYP19A1
47	breast carcinoma in situ	9.5	PGR CYP19A1
48	endometrial hyperplasia	9.5	PGR CYP19A1
49	ductal carcinoma in situ	9.5	PGR CYP19A1
50	endometriosis of ovary	9.4	PGR CYP19A1 AMH

Comorbidity relations with Subserous Uterine Fibroid via Phenotypic Disease Network (PDN):

Female Stress Incontinence

Submucous Uterine Fibroid

Graphical network of the top 20 diseases related to Subserous Uterine Fibroid:

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Symptoms & Phenotypes for Subserous Uterine Fibroid

MGI Mouse Phenotypes related to Subserous Uterine Fibroid:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	reproductive system	MP:0005389	9.02	AMH CLIP1 CYP19A1 OXT PGR

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Drugs & Therapeutics for Subserous Uterine Fibroid

Search Clinical Trials , NIH Clinical Center for Subserous Uterine Fibroid

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Genetic Tests for Subserous Uterine Fibroid

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Anatomical Context for Subserous Uterine Fibroid

MalaCards organs/tissues related to Subserous Uterine Fibroid:

⁴⁰

Uterus

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Publications for Subserous Uterine Fibroid

Articles related to Subserous Uterine Fibroid:

#	Title	Authors	PMID	Year
1	Pemphigus foliaceus clearance status postmyomectomy for an enlarged infarcted subserous uterine fibroid. ⁶¹	Fisher SH...Nousari CH	22583728	2012

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Genes for Subserous Uterine Fibroid

Genes related to Subserous Uterine Fibroid (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	HPSE2	Heparanase 2 (Inactive)	Protein Coding	5.6	DISEASES inferred ¹⁵
2	CLIP1	CAP-Gly Domain Containing Linker Protein 1	Protein Coding	5.54	DISEASES inferred ¹⁵
3	AMH	Anti-Mullerian Hormone	Protein Coding	4.76	DISEASES inferred ¹⁵
4	OXT	Oxytocin/Neurophysin I Prepropeptide	Protein Coding	4.44	DISEASES inferred ¹⁵
5	CYP19A1	Cytochrome P450 Family 19 Subfamily A Member 1	Protein Coding	4.26	DISEASES inferred ¹⁵
6	PGR	Progesterone Receptor	Protein Coding	3.79	DISEASES inferred ¹⁵

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Variations for Subserous Uterine Fibroid

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Expression for Subserous Uterine Fibroid

Search GEO for disease gene expression data for Subserous Uterine Fibroid.

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Pathways for Subserous Uterine Fibroid

Pathways related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Ovarian Infertility Genes ¹	10.13	PGR CYP19A1

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GO Terms for Subserous Uterine Fibroid

Biological processes related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	response to organic cyclic compound	GO:0014070	9.16	OXT AMH
2	response to estradiol	GO:0032355	8.96	OXT CYP19A1
3	mammary gland development	GO:0030879	8.62	PGR CYP19A1

Molecular functions related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	8.62	OXT AMH

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Sources for Subserous Uterine Fibroid

¹ BioSystems

² BitterDB

³ CDC

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²⁰ GeneAnalytics

²¹ GeneCards

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²⁴ GeneReviews

²⁵ Genetics Home Reference

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³² ICD10

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³⁵ IUPHAR

³⁶ KEGG

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⁴⁰ MalaCards

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⁵⁶ OMIM

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⁵⁹ PathCards

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⁶⁹ TGDB

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⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia