MCID: SBS001
MIFTS: 20

Subserous Uterine Fibroid

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Subserous Uterine Fibroid

MalaCards integrated aliases for Subserous Uterine Fibroid:

Name: Subserous Uterine Fibroid 12 15
Subserous Leiomyoma of Uterus 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13560
ICD9CM 34 218.2
SNOMED-CT 67 95280005
ICD10 32 D25.2
UMLS 71 C0153995

Summaries for Subserous Uterine Fibroid

Disease Ontology : 12 An uterine fibroid that is located adjacent to the outside of the uterus.

MalaCards based summary : Subserous Uterine Fibroid, also known as subserous leiomyoma of uterus, is related to leiomyoma and myofibroma. An important gene associated with Subserous Uterine Fibroid is HPSE2 (Heparanase 2 (Inactive)), and among its related pathways/superpathways is Ovarian Infertility Genes. Affiliated tissues include uterus, and related phenotype is reproductive system.

Related Diseases for Subserous Uterine Fibroid

Diseases related to Subserous Uterine Fibroid via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 30.1 PGR CYP19A1
2 myofibroma 10.3
3 pemphigus 10.3
4 pemphigus foliaceus 10.3
5 adhesions of uterus 10.0 PGR AMH
6 sex cord-gonadal stromal tumor 10.0 PGR AMH
7 endometritis 9.9 PGR OXT
8 benign metastasizing leiomyoma 9.8 PGR CYP19A1
9 postmenopausal atrophic vaginitis 9.8 CYP19A1 AMH
10 mammographic density 9.8 PGR CYP19A1
11 ovarian endometrioid stromal sarcoma 9.8 PGR CYP19A1
12 juvenile nasopharyngeal angiofibroma 9.8 PGR CYP19A1
13 gender identity disorder 9.8 PGR CYP19A1
14 progesterone-receptor positive breast cancer 9.8 PGR CYP19A1
15 estrogen excess 9.8 PGR CYP19A1
16 hypertrophy of breast 9.8 PGR CYP19A1
17 premature menopause 9.8 CYP19A1 AMH
18 steroid inherited metabolic disorder 9.8 CYP19A1 AMH
19 lobular neoplasia 9.8 PGR CYP19A1
20 46,xy sex reversal 2 9.8 CYP19A1 AMH
21 46,xy sex reversal 9.8 CYP19A1 AMH
22 prostatic hypertrophy 9.8 PGR CYP19A1
23 ovarian cyst 9.7 CYP19A1 AMH
24 sertoli cell tumor 9.7 PGR CYP19A1
25 luminal breast carcinoma a 9.7 PGR CYP19A1
26 amelogenesis imperfecta, type ig 9.7 PGR CYP19A1
27 ovarian hyperstimulation syndrome 9.7 CYP19A1 AMH
28 anovulation 9.7 CYP19A1 AMH
29 hypoactive sexual desire disorder 9.7 OXT CYP19A1
30 vaginal adenoma 9.7 OXT CYP19A1
31 breast fibroadenoma 9.7 PGR CYP19A1
32 vaginal benign neoplasm 9.7 OXT CYP19A1
33 estrogen-receptor negative breast cancer 9.7 PGR CYP19A1
34 primary pigmented nodular adrenocortical disease 9.7 PGR CYP19A1
35 premature ejaculation 9.7 OXT CYP19A1
36 teeth hard tissue disease 9.7 PGR CYP19A1
37 gynecomastia 9.7 PGR CYP19A1
38 female breast cancer 9.7 PGR CYP19A1
39 mccune-albright syndrome 9.7 CYP19A1 AMH
40 pseudohermaphroditism 9.7 CYP19A1 AMH
41 pre-malignant neoplasm 9.7 PGR CYP19A1
42 disorders of sexual development 9.6 CYP19A1 AMH
43 lipoid congenital adrenal hyperplasia 9.6 CYP19A1 AMH
44 sporadic breast cancer 9.6 PGR CYP19A1
45 in situ carcinoma 9.6 PGR CYP19A1
46 estrogen-receptor positive breast cancer 9.6 PGR CYP19A1
47 breast carcinoma in situ 9.5 PGR CYP19A1
48 endometrial hyperplasia 9.5 PGR CYP19A1
49 ductal carcinoma in situ 9.5 PGR CYP19A1
50 endometriosis of ovary 9.4 PGR CYP19A1 AMH

Comorbidity relations with Subserous Uterine Fibroid via Phenotypic Disease Network (PDN):


Female Stress Incontinence Submucous Uterine Fibroid

Graphical network of the top 20 diseases related to Subserous Uterine Fibroid:



Diseases related to Subserous Uterine Fibroid

Symptoms & Phenotypes for Subserous Uterine Fibroid

MGI Mouse Phenotypes related to Subserous Uterine Fibroid:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.02 AMH CLIP1 CYP19A1 OXT PGR

Drugs & Therapeutics for Subserous Uterine Fibroid

Search Clinical Trials , NIH Clinical Center for Subserous Uterine Fibroid

Genetic Tests for Subserous Uterine Fibroid

Anatomical Context for Subserous Uterine Fibroid

MalaCards organs/tissues related to Subserous Uterine Fibroid:

40
Uterus

Publications for Subserous Uterine Fibroid

Articles related to Subserous Uterine Fibroid:

# Title Authors PMID Year
1
Pemphigus foliaceus clearance status postmyomectomy for an enlarged infarcted subserous uterine fibroid. 61
22583728 2012

Variations for Subserous Uterine Fibroid

Expression for Subserous Uterine Fibroid

Search GEO for disease gene expression data for Subserous Uterine Fibroid.

Pathways for Subserous Uterine Fibroid

Pathways related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.13 PGR CYP19A1

GO Terms for Subserous Uterine Fibroid

Biological processes related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to organic cyclic compound GO:0014070 9.16 OXT AMH
2 response to estradiol GO:0032355 8.96 OXT CYP19A1
3 mammary gland development GO:0030879 8.62 PGR CYP19A1

Molecular functions related to Subserous Uterine Fibroid according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 OXT AMH

Sources for Subserous Uterine Fibroid

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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