Sudden Sensorineural Hearing Loss disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: SDD008 MIFTS: 45	Sudden Sensorineural Hearing Loss Categories: Rare diseases, Ear diseases
Genes Tissues Related diseases Publications Pathways Drugs Download Expand all tables

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Aliases & Classifications for Sudden Sensorineural Hearing Loss

MalaCards integrated aliases for Sudden Sensorineural Hearing Loss:

Name: Sudden Sensorineural Hearing Loss ⁵³ ³⁷

Acute Sensorineural Hearing Loss by Acute Acoustic Trauma or Sudden Deafness or Surgery Induced Acoustic Trauma ⁵³ ⁵⁹

Sudden Deafness ⁵³

Characteristics:

Orphanet epidemiological data:

⁵⁹

acute sensorineural hearing loss by acute acoustic trauma or sudden deafness or surgery induced acoustic trauma
Prevalence: 1-5/10000 (Europe);

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Ear diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Diseases of the ear and mastoid process

Diseases of inner ear

Other diseases of inner ear

Noise effects on inner ear

External Ids:

Orphanet ⁵⁹ ORPHA90059

ICD10 via Orphanet ³⁴ H83.3

KEGG ³⁷ H01704

Sources

Summaries for Sudden Sensorineural Hearing Loss

NIH Rare Diseases : ⁵³ Sudden sensorineural deafness is a condition that is characterized by rapid, unexplained hearing loss. More specifically, affected people experience a reduction in hearing of greater than 30 decibels, which may occur all at once or over several days. In most cases, only one ear is affected. People with sudden sensorineural deafness often become dizzy, have ringing in their ears (tinnitus), or both (40% of the cases). The condition has a variety of causes, including infection, inflammation, tumors, trauma, exposure to toxins and conditions that affect the inner ear such as Ménière's disease. About half of people with sudden sensorineural deafness will recover some or all of their hearing spontaneously and about 85% of those who receive treatment will recover some of their hearing.

MalaCards based summary : Sudden Sensorineural Hearing Loss, also known as acute sensorineural hearing loss by acute acoustic trauma or sudden deafness or surgery induced acoustic trauma, is related to varicose veins and antiphospholipid syndrome. An important gene associated with Sudden Sensorineural Hearing Loss is F5 (Coagulation Factor V), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Dexamethasone and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include testes, endothelial and bone, and related phenotypes are Increased shRNA abundance and homeostasis/metabolism

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Related Diseases for Sudden Sensorineural Hearing Loss

Diseases related to Sudden Sensorineural Hearing Loss via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)

#	Related Disease	Score	Top Affiliating Genes
1	varicose veins	28.6	F2 F5 MTHFR SERPINC1
2	antiphospholipid syndrome	28.6	F2 F5 MTHFR SERPINC1
3	cerebrovascular disease	28.3	F2 F5 IL6 MTHFR
4	myocardial infarction	26.6	F2 F5 IL6 ITGB3 MTHFR SERPINC1
5	sensorineural hearing loss	11.2
6	ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus	11.2
7	inferior vena cava interruption	10.5	F5 MTHFR
8	amaurosis fugax	10.5	F5 MTHFR
9	catastrophic antiphospholipid syndrome	10.5	F5 MTHFR
10	paracetamol poisoning	10.4	F2 F5
11	cerebral sinovenous thrombosis	10.4	F2 F5
12	hemoglobin e disease	10.4	F2 F5
13	factor viii deficiency	10.4	F2 F5
14	mesenteric vascular occlusion	10.4	F2 MTHFR
15	schizencephaly	10.3	F5 MTHFR
16	ischemic neuropathy	10.3	F2 MTHFR
17	scott syndrome	10.3	F2 F5
18	acute liver failure	10.3	F2 F5
19	severe hemophilia a	10.3	F2 F5
20	buerger disease	10.3	F2 MTHFR
21	endotheliitis	10.2
22	benign paroxysmal positional nystagmus	10.2
23	vertigo, benign recurrent	10.2
24	afibrinogenemia	10.2	F2 F5
25	meningococcemia	10.2	F5 SERPINC1
26	von willebrand's disease	10.2	F2 F5
27	legg-calve-perthes disease	10.2	F5 SERPINC1
28	factor xii deficiency	10.2	F5 SERPINC1
29	factor v deficiency	10.2	F2 F5
30	nutritional deficiency disease	10.2	F2 MTHFR
31	intestinal impaction	10.2	F2 SERPINC1
32	fournier gangrene	10.1	F2 SERPINC1
33	leech infestation	10.1	F2 SERPINC1
34	alpha-2-plasmin inhibitor deficiency	10.1	F2 SERPINC1
35	lupus erythematosus	10.1
36	multiple sclerosis	10.1
37	acute myocardial infarction	10.1
38	labyrinthitis	10.1
39	giant hemangioma	10.1	F2 SERPINC1
40	blue toe syndrome	10.1	F2 SERPINC1
41	intracranial embolism	10.1	F2 SERPINC1
42	anterior spinal artery syndrome	10.1	F2 SERPINC1
43	subendocardial myocardial infarction	10.1	F2 SERPINC1
44	purpura fulminans	10.1	F2 SERPINC1
45	korean hemorrhagic fever	10.1	F2 SERPINC1
46	esophageal varix	10.1	F2 SERPINC1
47	hypersplenism	10.1	F2 SERPINC1
48	coronary thrombosis	10.1	ITGB3 SERPINC1
49	factor xi deficiency	10.1	F2 SERPINC1
50	auditory system disease	10.1

Graphical network of the top 20 diseases related to Sudden Sensorineural Hearing Loss:

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Symptoms & Phenotypes for Sudden Sensorineural Hearing Loss

GenomeRNAi Phenotypes related to Sudden Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance	GR00327-A	8.8	MTHFR F5 ITGB3

MGI Mouse Phenotypes related to Sudden Sensorineural Hearing Loss:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.85	F2 F5 IL6 ITGB3 MTHFR SERPINC1
2	cardiovascular system	MP:0005385	9.8	ITGB3 SERPINC1 F2 F5 IL6
3	integument	MP:0010771	9.72	F2 F5 IL6 ITGB3 MTHFR
4	mortality/aging	MP:0010768	9.63	F2 F5 IL6 ITGB3 MTHFR SERPINC1
5	liver/biliary system	MP:0005370	9.56	F5 IL6 ITGB3 SERPINC1
6	nervous system	MP:0003631	9.43	IL6 ITGB3 MTHFR SERPINC1 F2 F5
7	reproductive system	MP:0005389	9.02	F2 IL6 ITGB3 MTHFR SERPINC1

Sources

Drugs & Therapeutics for Sudden Sensorineural Hearing Loss

Drugs for Sudden Sensorineural Hearing Loss (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Not Applicable

50-02-2

5743

Synonyms:

(3H)-Dexamethasone

.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol

.gamma.corten

137098-19-2

16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol

16.alpha.-Methyl-9.alpha.-fluoroprednisolone

16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol

16alpha -Methyl-9alpha -fluoroprednisolone

16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol

16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol

16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone

16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone

16alpha-Methyl-9alpha-fluoroprednisolone

16-alpha-Methyl-9-alpha-fluoroprednisolone

16a-Methyl-9a-fluoro-1-dehydrocortisol

16α-methyl-9α-fluoro-1-dehydrocortisol

16α-Methyl-9α-fluoro-1-dehydrocortisol

1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone

1-dehydro-16alpha -Methyl-9alpha -fluorohydrocortisone

1-dehydro-16alpha-Methyl-9alpha-fluorohydrocortisone

1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone

1-dehydro-16a-Methyl-9a-fluorohydrocortisone

1-dehydro-16α-methyl-9α-fluorohydrocortisone

1-Dehydro-16α-methyl-9α-fluorohydrocortisone

23495-06-9

31375_FLUKA

46165_FLUKA

46165_RIEDEL

50-02-2

8054-59-9

9.alpha.-Fluoro-16.alpha.-methylprednisolone

906422-84-2

9a-fluoro-16a-Methylprednisolone

9a-fluoro-16BETA-METHYLPREDNISOLONE

9A-FLUORO-16BETA-METHYLPREDNISOLONE

9alpha -fluoro-16alpha -Methylprednisolone

9alpha-fluoro-16alpha-Methylprednisolone

9alpha-fluoro-16alpha-Methyl-prednisolone

9-alpha-fluoro-16-alpha-Methylprednisolone

9alpha-Fluoro-16alpha-methylprednisolone

9-alpha-Fluoro-16-alpha-methylprednisolone

9-fluoro-11,17,21-Trihydroxy-16-methylpregna-1,4-diene-3,20-dione

9-fluoro-11alpha -Methylpregna-1,4-diene-3,20-dione

9-fluoro-16-Methylprednisolone

9α-fluoro-16α-methylprednisolone

9α-Fluoro-16α-methylprednisolone

AC-11056

AC1L1L1H

AC1Q29DM

Adexone

Aeroseb-D

Aeroseb-dex

Aeroseb-Dex

AI3-50934

Ak dex OPH otic soln 0.1%

Alcon brand OF dexamethasone

Alcon Brand of Dexamethasone

alpha -fluoro-16-alpha -Methylcortisol

Anaflogistico

Aphtasolon

Aphthasolone

apo-Dexamethasone

Auxiron

Azimycin (veterinary)

Azium

Azium (veterinary)

Azium (Veterinary)

BIDD:ER0494

BIDD:PXR0060

Bisu Ds

Bisu DS

BRD-K38775274-001-02-3

BRD-K38775274-001-06-4

BSPBio_000995

C15643

C22H29FO5

Calonat

CCRIS 7067

CHEBI:41879

CHEMBL384467

CID5743

Corson

Corsone

Cortisumman

CPD001227192

CPD-10549

D00292

D003907

D1756_SIGMA

D4902_SIGMA

D6645_SIGMA

D8893_SIGMA

D9184_SIGMA

DB01234

Decacort

Decacortin

Decaderm

Decadron

Decadron (TN)

Decadron Tablets, Elixir

Decadron, Dexamethasone

Decadron-La

Decadron-LA

Decagel

Decaject

Decaject l.a.

Decaject L.A.

Decaject-l.a.

Decaject-L.A.

Decalix

Decameth

Decasone

Decaspray

Dectancyl

Dekacort

delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol

delta1-9alpha-Fluoro-16alpha-methylcortisol

Delta1-9alpha-fluoro-16alpha-Methylcortisol

Deltafluorene

Dergramin

Deronil

Desadrene

Desametasone

Desametasone [Dcit]

Desametasone [DCIT]

Desamethasone

Desameton

Deseronil

DEX

Dexa

DEXA

Dexa mamallet

Dexa Mamallet

Dexacen-4

Dexacidin

Dexacort

Dexacortal

Dexa-cortidelt

Dexa-Cortidelt

Dexacortin

Dexa-cortisyl

Dexa-Cortisyl

Dexadeltone

Dexafarma

Dexair

Dexalona

Dexaltin

Dexa-Mamallet

Dexametasona

Dexametasona [INN-Spanish]

Dexametasone

Dexameth

Dexamethansone

dexamethasone

Dexamethasone

Dexamethasone (JP15/USP/INN)

Dexamethasone [INN:BAN:JAN]

Dexamethasone acetate

Dexamethasone Acetate

Dexamethasone alcohol

Dexamethasone Alcohol

Dexamethasone base

Dexamethasone Base

Dexamethasone intensol

Dexamethasone Intensol

Dexamethasone sodium phosphate

Dexamethasone Sodium Phosphate

Dexamethasone-omega

Dexamethasonum

Dexamethasonum [INN-Latin]

Dexamethazone

Dexamonozon

Dexapolcort

Dexapos

Dexaprol

Dexa-scheroson

Dexa-Scheroson

Dexa-sine

Dexa-Sine

Dexason

Dexasone

Dexasone 0.5MG

Dexasone 0.75MG

Dexasone 4MG

Dexasporin

Dex-ide

Dex-Ide

Dexinolon

Dexinoral

Dexone

Dexone 0.5

DEXONE 0.5

Dexone 0.75

DEXONE 0.75

Dexone 1.5

DEXONE 1.5

Dexone 4

DEXONE 4

Dexonium

Dexpak

Dextelan

Dezone

Dinormon

DXM

Dxms

DXMS

ECR brand OF dexamethasone

ECR Brand of Dexamethasone

EINECS 200-003-9

Fluormethylprednisolone

Fluormone

Fluorocort

Fortecortin

Foy brand OF dexamethasone

Foy Brand of Dexamethasone

FT-0080377

Gammacorten

Hexadecadrol

Hexadrol

Hexadrol elixir

Hexadrol Elixir

Hexadrol Tablets

Hl-dex

Hl-Dex

HL-Dex

HMS1792A17

HMS1990A17

HMS2089N13

HSDB 3053

I06-1196

ICN brand OF dexamethasone

ICN Brand of Dexamethasone

IontoDex

isopto-Dex

Isopto-Dex

Lokalison F

Loverine

LS-7300

Luxazone

Maxidex

Maxidex ont 0.1%

Maxidex sus 0.1%

Maxitrol

Mediamethasone

Merck brand OF dexamethasone

Merck Brand of Dexamethasone

Merz brand 1 OF dexamethasone

Merz Brand 1 of Dexamethasone

Merz brand 2 OF dexamethasone

Merz Brand 2 of Dexamethasone

Methylfluorprednisolone

Mexidex

Millicorten

MK 125

MLS001055412

MLS001332507

MLS001332508

MolMap_000018

MolPort-003-846-433

Mymethasone

Naquasone (veterinary)

NCGC00091019-01

NCGC00091019-02

NCGC00091019-03

NCGC00091019-04

NCGC00091019-05

nchembio809-comp2

NCI60_003067

Neomycin and polymyxin b sulfates and dexamethasone

Neomycin and polymyxin b sulphates and dexamethasone

NSC 34521

NSC34521

Ocu-trol

Ocu-Trol

Oradexon

OTO-104

Pet derm III

Pet Derm Iii

Pet Derm III

Pet-Derm Iii

PHL-Dexamethasone

PMS Dexamethasone elixir 0.5mg/5ML

PMS-Dexamethasone

Policort

Posurdex

Prednisolon F

Prednisolone F

Prodex

S1322_Selleck

SAM002548948

Sandoz dexamethasone

SGCUT00126

Sk-Dexamethasone

SK-Dexamethasone

SMP1_000092

SMR000857119

SMR001227192

Spectrum5_002019

Spoloven

ST50307091

Sunia sol D

Sunia Sol D

Superprednol

TL8003317

to_000038

Tobradex

Tobramycin and dexamethasone

Tresaderm (veterinary)

Turbinaire

UNII-7S5I7G3JQL

Visumetazone

WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1

ZINC03875332

Cisplatin

Approved

Phase 4

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatine

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Dexamethasone acetate

Phase 4,Phase 3,Phase 2,Not Applicable

1177-87-3

glucocorticoids

Phase 4,Phase 2,Phase 3,Not Applicable

protease inhibitors

Phase 4,Phase 3,Phase 2,Not Applicable

Gastrointestinal Agents

Phase 4,Phase 3,Phase 2,Not Applicable

HIV Protease Inhibitors

Phase 4,Phase 3,Phase 2,Not Applicable

Hormone Antagonists

Phase 4,Phase 2,Phase 3,Not Applicable

Dexamethasone 21-phosphate

Phase 4,Phase 2,Not Applicable

Hormones

Phase 4,Phase 2,Phase 3,Not Applicable

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Phase 2,Phase 3,Not Applicable

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Antiemetics

Phase 4,Phase 3,Phase 2,Not Applicable

Anti-Inflammatory Agents

Phase 4,Phase 2,Phase 3,Not Applicable

BB 1101

Phase 4,Phase 3,Phase 2,Not Applicable

Autonomic Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Antineoplastic Agents, Hormonal

Phase 4,Phase 2,Phase 3,Not Applicable

Prednisone

Approved, Vet_approved

Phase 2, Phase 3,Phase 3

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Adasone

AI3-52939

Ancortone

apo-Prednisone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

Prednisolone

Approved, Vet_approved

Phase 3

50-24-8

5755

Synonyms:

(11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione

(11β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione

.DELTA.1-Cortisol

.DELTA.1-Dehydrocortisol

.DELTA.1-Dehydrohydrocortisone

.DELTA.1-Hydrocortisone

.delta.-Cortef

.delta.-Stab

1,2-Dehydrohydrocortisone

1,4-Pregnadiene-11b,17a,21-triol-3,20-dione

1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione

1,4-Pregnadiene-11β,17α,21-triol-3,20-dione

1,4-Pregnadiene-3,20-dione-11b,17a,21-triol

1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol

1,4-Pregnadiene-3,20-dione-11β,17α,21-triol

1-Dehydrocortisol

1-Dehydrohydrocortisone

3,20-dioxo-11b,17a,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene

3,20-dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene

46656_FLUKA

46656_RIEDEL

50-24-8

58201-11-9

8056-11-9

AC-1773

AC1L1L2E

Ak-Pred

Ak-Tate

Alphadrol

Articulose-50

Bio-0666

BPBio1_000164

BRD-K98039984-001-03-0

BRN 1354103

BSPBio_000148

Bubbli-Pred

C07369

CCRIS 980

CHEBI:8378

CHEMBL131

CID5755

Codelcortone

Co-Hydeltra

CO-Hydeltra

component of Ataraxoid

component of K-Predne-Dome

Cordrol

Cortalone

Cotogesic

Cotolone

CPD000718761

D00472

D011239

DB00860

Decaprednil

Decortin H

Delcortol

Delta F

delta(1)-Cortisol

delta(1)-Dehydrocortisol

Delta(1)-Dehydrocortisol

delta(1)-Dehydrohydrocortisone

Delta(1)-dehydrohydrocortisone

Delta(1)-Dehydrohydrocortisone

delta(1)-Hydrocortisone

Delta(1)-Hydrocortisone

delta(sup 1)-Cortisol

delta(sup 1)-Dehydrocortisol

delta(sup 1)-Dehydrohydrocortisone

delta(sup 1)-Hydrocortisone

Delta-Cortef

Delta-Cortef (TN)

Deltacortenol

Deltacortril

Deltacortril Enteric

delta-dehydrocortisol

delta-dehydrohydrocortisone

Delta-Ef-Cortelan

delta-hydrocortisone

Deltahydrocortisone

Deltasolone

Delta-stab

Delta-Stab

Deltisilone

Depo-Medrol

Derpo Pd

Derpo PD

Dexa-Cortidelt hostacortin H

Dexa-Cortidelt Hostacortin H

Di adreson F

Di Adreson F

Di-adreson F

Di-Adreson F

Di-adreson-F

DiAdresonF

Di-Adreson-F

Dicortol

Donisolone

Dydeltrone

Eazolin D

Econopred

Econopred Plus

EINECS 200-021-7

Erbacort

Erbasona

Estilsona

Fernisolone

Fernisolone P

Fernisolone-P

Flamasone

HMS1568H10

HMS2090J05

Hostacortin H

HSDB 3385

Hydeltra

Hydeltrasol

Hydeltra-Tba

Hydeltrone

Hydrodeltalone

Hydrodeltisone

Hydroretrocortin

Hydroretrocortine

Inflamase Forte

Inflamase Mild

I-Pred

K 1557

Key-Pred

Klismacort

Lentosone

Lite Pred

LMST02030179

LS-7669

Medrol

Medrol Acetate

Metacortandralone

Methylprednisolone acetate

Methylprednisolone Acetate

Meticortelone

Meti-Derm

Metreton

MLS001304083

MLS002154250

MLS002207037

MolPort-002-507-147

M-Predrol

NCGC00179649-01

Neo-Delta-Cortef

Nisolone

Nor-Pred T.B.A.

NSC 9120

NSC9120

NSC9900

Ocu-Pred

Ocu-Pred Forte

Ophtho-Tate

Orapred

P0152_SIGMA

P0637

P6004_SIGMA

Panafcortelone

Paracortol

Paracotol

Pediapred

Poly-Pred

PRDL

Precortalon

Precortancyl

Precortilon

Precortisyl

Pred Forte

Pred Mild

Predair

Predair A

Predair Forte

Predalone 50

Predalone T.B.A.

Predate

Predate Tba

Predate-50

Predcor-25

Predcor-50

Predcor-Tba

PRED-G

Predisolone sodium phosphate

Predisolone Sodium Phosphate

Predne-Dome

Prednelan

Prednicen

Predni-Dome

Predniliderm

Predniretard

Prednis

Prednisolona

Prednisolona [INN-Spanish]

prednisolone

Prednisolone (anhydrous)

Prednisolone (JP15/USP/INN)

Prednisolone [INN:BAN:JAN]

Prednisolone acetate

Prednisolone Acetate

Prednisolone sodium phosphate

Prednisolone Sodium Phosphate

Prednisolone tebutate

Prednisolone Tebutate

Prednisolonum

Prednisolonum [INN-Latin]

Predonin

Predonine

Prelone

Prenolone

Prestwick_404

Prestwick0_000274

Prestwick1_000274

Prestwick2_000274

Prestwick3_000274

Rolisone

S1737_Selleck

SAM002264639

Scherisolon

SMR000718761

Solone

SPBio_002367

Steran

Sterane

Sterolone

Supercortisol

Ulacort

Ultra Pred

Ultracorten H

Ultracortene H

Ultracortene-H

Ultracortene-hydrogen

Ultracortene-Hydrogen

UNII-9PHQ9Y1OLM

ZINC03833821

δ(1)-dehydrocortisol

δ(1)-dehydrohydrocortisone

δ(1)-hydrocortisone

Methylprednisolone

Approved, Vet_approved

Phase 3

83-43-2

6741

Synonyms:

(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione

(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione

.DELTA.1-6.alpha.-Methylhydrocortisone

11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione

11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione

121673-01-6

1-dehydro-6alpha-Methylhydrocortisone

1-Dehydro-6alpha-methylhydrocortisone

1-dehydro-6a-Methylhydrocortisone

1-dehydro-6α-methylhydrocortisone

4-08-00-03498 (Beilstein Handbook Reference)

46436_FLUKA

46436_RIEDEL

570-35-4

6 Methylprednisolone

6.alpha.-Methylprednisolone

6923-42-8

6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione

6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione

6alpha-Methylprednisolone

6-alpha-Methylprednisolone

6a-Methyl-11b,17a,21-triol-1,4-pregnadiene-3,20-dione

6-Methylprednisolone

6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione

83-43-2

AC1L1N7A

Artisone-wyeth

Artisone-Wyeth

Besonia

Bio-0658

BPBio1_000174

BRD-K35240538-001-03-1

BRN 2340300

BSPBio_000158

CHEBI:6888

CHEMBL650

CID6741

CPD000058330

D00407

D008775

DB00959

delta(1)-6alpha-Methylhydrocortisone

Delta(1)-6alpha-Methylhydrocortisone

delta(1)-6a-Methylhydrocortisone

delta(sup 1)-6-alpha-Methylhydrocortisone

Depo-Medrol (acetate)

Dopomedrol

EINECS 201-476-4

Esametone

Firmacort

HMS1568H20

HMS2090B13

HSDB 3127

Lemod

LMST02030178

LS-118498

M0639_SIGMA

M1665

Medesone

Medixon

Medlone 21

Medrate

Medric acid

Medrol

Medrol (TN)

Medrol adt pak

Medrol Adt Pak

Medrol dosepak

Medrol Dosepak

Medrol, Solu-Medrol, Medrone, Methylprednisolone

Medrone

MEPRDL

Mesopren

Metastab

Methyleneprednisolone

Methylprednisolon

methylprednisolone

Methylprednisolone

Methylprednisolone (JP15/USP/INN)

Methylprednisolone [USAN:INN:BAN:JAN]

Methylprednisolone, 6-alpha

Methylprednisolonum

Methylprednisolonum [INN-Latin]

methylprenisolone

Metilbetasone

Metilprednisolona

Metilprednisolona [INN-Spanish]

Metilprednisolone

Metilprednisolone [Dcit]

Metilprednisolone [DCIT]

Metipred

Metrisone

Metrocort

Metysolon

MLS000028541

MLS001148159

MLS002207191

Moderin

MolPort-002-528-554

NCGC00022735-03

NCI60_001657

Nirypan

Noretona

NSC19987

NSC-19987

Predni N Tablinen

Prednol- L

Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)

Prestwick_622

Prestwick0_000279

Prestwick1_000279

Prestwick2_000279

Prestwick3_000279

Promacortine

Reactenol

S1733_Selleck

SAM002589984

Sieropresol

SMR000058330

Solomet

SPBio_002377

Summicort

Suprametil

U 7532

UNII-X4W7ZR7023

Urbason

Urbasone

Wyacort

ZINC03875560

δ(1)-6a-methylhydrocortisone

δ(1)-6α-methylhydrocortisone

Prednisolone acetate

Phase 3

Methylprednisolone acetate

Phase 3

Methylprednisolone Hemisuccinate

Phase 3

Neuroprotective Agents

Phase 3

Prednisolone hemisuccinate

Phase 3

Prednisolone phosphate

Phase 3

Protective Agents

Phase 3

Anesthetics

Phase 3

Ancrod

Approved, Investigational

Phase 1, Phase 2

9046-56-4

Pharmaceutical Solutions

Phase 2,Phase 1

Interleukin 1 Receptor Antagonist Protein

Phase 1, Phase 2,Phase 2

Antirheumatic Agents

Phase 1, Phase 2,Phase 2

Fibrinolytic Agents

Phase 1, Phase 2

Anticoagulants

Phase 1, Phase 2

Fludrocortisone

Approved, Investigational

Not Applicable

127-31-1

31378

Synonyms:

(11beta)-9-Fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione

(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one

127-31-1

4-08-00-03427 (Beilstein Handbook Reference)

9 .alpha. FF

9 alpha FF

9 alpha Fludrohydrocortisone

9 alpha fluoro 17 Hydroxycorticosterone

9 alpha Fluoro 17 Hydroxycorticosterone

9 alpha Fluorohydrocortisone

9 alpha-Fludrocortisone

9 alpha-fluoro-17-Hydroxycorticosterone

9 alpha-Fluoro-17-Hydroxycorticosterone

9 alpha-Fluorocortisol

9 alpha-Fluorohydrocortisone

9 fluoro 17 Hydroxycortisone

9 Fluoro 17 Hydroxycortisone

9 Fluorocortisol

9 Fluorohydrocortisone

9.alpha.-Fluoro-11.beta.,17.alpha.,21-trihydroxy-4-pregnene-3,20-dione

9.alpha.-Fluoro-17-hydroxycorticosterone

9.alpha.-Fluorocortisol

9.alpha.-Fluorohydrocortisone

9-AF

9-AFH

9a-FLUOROCORTISOL

9alpha-Fludrocortisone

9-alpha-Fludrocortisone

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione

9alpha-Fluoro-17-hydroxycorticosterone

9-alpha-Fluoro-17-hydroxycorticosterone

9alpha-Fluorocortisol

9-alpha-Fluorocortisol

9alpha-FLUOROCORTISOL

9ALPHA-FLUOROCORTISOL

9alpha-Fluoro-hydrocortisone

9-alpha-Fluorohydrocortisone

9-Fluoro-11.beta.,17,21-trihydroxypregn-4-ene-3,20-dione

9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione

9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione

9-fluoro-17-Hydroxycortisone

9-Fluoro-17-Hydroxycortisone

9-Fluorocortisol

9-Fluorohydrocortisone

9α-fluorocortisol

AC1L1LI8

AC1Q5HJH

Alflorone

Astonin

Astonin H

Astonin merck

Astonin Merck

Astonin-H

Astonin-H (TN)

BRN 3014278

C07004

C21H29FO5

CHEBI:50885

CHEMBL1201388

CID31378

D005438

D07967

DB00687

DB02478

EINECS 204-833-2

FCOL

F-COL

F-Cortef

Florinef

Fludrocortison

Fludrocortisona

Fludrocortisona [INN-Spanish]

fludrocortisone

Fludrocortisone

Fludrocortisone (INN)

Fludrocortisone [INN:BAN]

Fludrocortisonum

Fludrocortisonum [INN-Latin]

Fludrocortone

Fludrone

Fludronef

Fluodrocortisone

Fluohydrisone

Fluohydrocortisone

Fluorocortisol

Fluorocortisone

HSDB 3332

Hydrocortisone-9alpha-fluoro

LMST02030103

LS-118690

Merck brand OF fludrocortisone

Merck Brand of Fludrocortisone

Merck, astonin

Merck, Astonin

MolPort-005-943-437

NCGC00181081-01

NSC 11318

NSC11318

Pregn-4-ene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy- (8CI)

Prestwick_648

StC 1400

U 5963

UNII-U0476M545B

WLN: L E5 B666 OV MUTJ A1 BF CQ E1 FV1Q FQ

ZINC04097304

ZK5

Mineralocorticoids

Not Applicable

interferons

Anti-Infective Agents

Interferon-alpha

Antiviral Agents

Interventional clinical trials:

(show all 18)

#	Name	Status	NCT ID	Phase	Drugs
1	Prevention of Cisplatin-Induced Hearing Loss by Intratympanic Dexamethasone Treatment	Completed	NCT01372904	Phase 4	Dexamethasone Phosphate
2	Bed Rest for Idiopathic Sudden Sensorineural Hearing Loss	Unknown status	NCT00416143	Phase 2, Phase 3	prednisone - oral corticosteroid 1mg/kg/D for 1 week
3	Sudden Deafness Treatment Trial	Completed	NCT00097448	Phase 3	prednisone;methylprednisolone sodium succinate
4	Safety and Efficacy of Intratympanic Application of Dexamethasone Via Catheter in Patients With Sudden Hearing Loss	Completed	NCT00335920	Phase 3	Dexamethasone-dihydrogenphosphate (4mg/ml)
5	AM-111 in the Treatment of Acute Inner Ear Hearing Loss	Completed	NCT02561091	Phase 3	AM-111 0.4 mg/ml;AM-111 0.8 mg/ml
6	Safety and Efficacy of STR001-IT and STR001-ER in Patients With SSHL	Not yet recruiting	NCT03331627	Phase 3	STR001-IT and STR001-ER
7	Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment	Terminated	NCT02809118	Phase 3	AM-111 0.4 mg/ml;AM-111 0.8 mg/ml
8	The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease	Completed	NCT01950312	Phase 2	gevokizumab
9	Efficacy of AM-111 in Patients With Acute Sensorineural Hearing Loss	Completed	NCT00802425	Phase 2	AM-111;placebo
10	A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease	Completed	NCT01267994	Phase 1, Phase 2	Anakinra
11	High Dose Oral Steroids in Sudden Sensorineural Hearing Loss	Recruiting	NCT03255473	Phase 2	Dexamethasone;Prednisone
12	Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing Loss	Recruiting	NCT01621256	Phase 1, Phase 2	Ancrod;Saline solution
13	Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss	Terminated	NCT02414152	Phase 1, Phase 2	anakinra
14	Fludrocortisone for Sudden Hearing Loss	Unknown status	NCT01186185	Not Applicable	Fludrocortisone
15	Sudden Hearing Loss Multi-center Clinical Trial	Unknown status	NCT02026479	Not Applicable	Dexamethasone Phosphate;Dexamethasone Phosphate;Ginaton
16	The Effect of Antiviral Therapy With Pegylated Interferon-alpha on Auditory Disability	Completed	NCT01265693
17	Effects of Repetitive Hyperbaric Oxygen Therapy in Patients With Acute Ischaemic Stroke	Recruiting	NCT03431402	Not Applicable	Hyperbaric oxygen
18	Hyperbaric Oxygen Therapy Registry	Enrolling by invitation	NCT02483650

Search NIH Clinical Center for Sudden Sensorineural Hearing Loss

Sources

Genetic Tests for Sudden Sensorineural Hearing Loss

Sources

Anatomical Context for Sudden Sensorineural Hearing Loss

MalaCards organs/tissues related to Sudden Sensorineural Hearing Loss:

⁴¹

Testes, Endothelial, Bone, Neutrophil, Brain, Heart, Myeloid

Sources

Publications for Sudden Sensorineural Hearing Loss

Articles related to Sudden Sensorineural Hearing Loss:

(show top 50) (show all 389)

#	Title	Authors	Year
1	Prognostic factors regarding the hearing outcome in severe to profound sudden sensorineural hearing loss treated by tympanotomy and sealing of labyrinthine windows after ineffective systemic corticosteroid application. ( 29855690 )	Thomas J.P....Dazert S.	2018
2	Association of Sudden Sensorineural Hearing Loss With Risk of Cardiocerebrovascular Disease: A Study Using Data From the Korea National Health Insurance Service. ( 29270613 )	Kim J.Y....Kim D.K.	2018
3	Mobile Hearing Testing Applications and the Diagnosis of Sudden Sensorineural Hearing Loss: A Cautionary Tale. ( 29227445 )	Sethi R.K.V....Remenschneider A.K.	2018
4	Hypertrophic Pachymeningitis of the Internal Auditory Canal: A Rare Case of Unilateral Sudden Sensorineural Hearing Loss. ( 29938521 )	Muelleman T....Staecker H.	2018
5	Assessment of Spontaneous Recovery Rates in Patients With Idiopathic Sudden Sensorineural Hearing Loss. ( 29931029 )	Bayoumy A.B....Alexander de Ru J.	2018
6	Comparison of intratympanic dexamethasone therapy and hyperbaric oxygen therapy for the salvage treatment of refractory high-frequency sudden sensorineural hearing loss. ( 29891394 )	Sun H....Ma Z.	2018
7	Efficacy of systemic and intratympanic corticosteroid combination therapy versus intratympanic or systemic therapy in patients with idiopathic sudden sensorineural hearing loss: a randomized controlled trial. ( 29149379 )	Ashtiani M.K....Sahebi L.	2018
8	Oral and intratympanic steroid therapy for idiopathic sudden sensorineural hearing loss. ( 29721537 )	Hara J.H....Burgess L.P.	2018
9	The role of explorative tympanotomy in patients with sudden sensorineural hearing loss with and without perilymphatic fistula. ( 29055686 )	Prenzler N.K....El-Saied S.	2018
10	A protocol for a network meta-analysis of interventions to treat patients with sudden sensorineural hearing loss. ( 29769117 )	Ahmadzai N....Hutton B.	2018
11	Delayed Recovery in Pediatric Sudden Sensorineural Hearing Loss Predicted via Magnetic Resonance Imaging. ( 29717656 )	Wu X....Chen K.	2018
12	Inpatient treatment of patients with idiopathic sudden sensorineural hearing loss: a population-based healthcare research study. ( 29330597 )	Heuschkel A....Guntinas-Lichius O.	2018
13	Association of Vertigo With Hearing Outcomes in Patients With Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis. ( 29931169 )	Yu H....Li H.	2018
14	Idiopathic Sudden Sensorineural Hearing Loss Is Not a Sentinel Event for Acute Myocardial Infarction. ( 29912831 )	Crowson M.G....Vambutas A.	2018
15	Prognostic role of haematological indices in sudden sensorineural hearing loss: Review and meta-analysis. ( 29684383 )	Cao Z....Chen B.	2018
16	Can A Sudden Sensorineural Hearing Loss Occur Due to Miliary Tuberculosis? ( 29036759 )	Min S.K....Mun S.K.	2018
17	Comparison of 2 and 4 Intratympanic Steroid Injections in the Treatment of Idiopathic Sudden Sensorineural Hearing Loss. ( 29411622 )	Suzuki H....Ohbuchi T.	2018
18	Association of Idiopathic Sudden Sensorineural Hearing Loss With Affective Disorders. ( 29852049 )	Kim J.Y....Kim D.K.	2018
19	The Clinical Value of Vertigo as a Prognostic Indicator of Outcome in Sudden Sensorineural Hearing Loss. ( 29931206 )	Rauch S.D.	2018
20	Mobile phone usage does not affect sudden sensorineural hearing loss. ( 29179790 )	Sagiv D....Shapira Y.	2018
21	Association of Metabolic Syndrome With Sudden Sensorineural Hearing Loss. ( 29450496 )	Jung S.Y....Yeo S.G.	2018
22	Coexistence of IL-6 -572C/G and ICAM-1 K469E Polymorphisms among Patients with Sudden Sensorineural Hearing Loss. ( 29695657 )	Tian G....Yang J.	2018
23	The Characteristic and Short-Term Prognosis of Tinnitus Associated with Sudden Sensorineural Hearing Loss. ( 29861716 )	Ding X....FENG X.	2018
24	Modified Siegel's criteria for sudden sensorineural hearing loss: Reporting recovery outcomes with matched pretreatment hearing grades. ( 29929833 )	Cheng Y.F....Liao W.H.	2018
25	Effect of Antioxidant Vitamins as Adjuvant Therapy for Sudden Sensorineural Hearing Loss: Systematic Review Study. ( 29929192 )	Ibrahim I....da Silva S.D.	2018
26	Sudden Sensorineural Hearing Loss in the Department of Defense. ( 29631507 )	Hughes C.K....Laury A.M.	2018
27	Acupuncture as an early treatment for idiopathic sudden sensorineural hearing loss (ISSNHL) patients with flat or high-frequency drop audiograms: study protocol for a randomized controlled trial. ( 29973265 )	Shang K....Zhang C.	2018
28	Is nucleate cell count and neutrophil to lymphocyte ratio related to patients with audiographically distinct sudden sensorineural hearing loss? ( 29768325 )	Sun Y....Yin S.	2018
29	Comparison between Bilateral and Unilateral Sudden Sensorineural Hearing Loss. ( 29363646 )	Bing D....Wang Q.J.	2018
30	Letter to the Editor Regarding Comparison of 2 and 4 Intratympanic Steroid Injections in the Treatment of Idiopathic Sudden Sensorineural Hearing Loss by Suzuki et al. ( 29911911 )	Sutton L....Lechner M.	2018
31	Does the addition of hyperbaric oxygen therapy to conventional treatment modalities influence the outcome of soldiers with idiopathic sudden sensorineural hearing loss? ( 29431146 )	Chi T.H....Yuan C.H.	2018
32	International consensus (ICON) on treatment of sudden sensorineural hearing loss. ( 29396226 )	Marx M....Sterkers O.	2018
33	Predicting the hearing outcome in sudden sensorineural hearing loss via machine learning models. ( 29356346 )	Bing D....Wang Q.	2018
34	Hyperbaric Oxygen Therapy as Adjuvant Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Systemic Steroids. ( 28423374 )	Hosokawa S....Mineta H.	2017
35	Prognosticating hearing outcome in patients with idiopathic sudden sensorineural hearing loss by means of otoacoustic emissions and auditory brainstem response. ( 29236273 )	Zarandy M.M....Ebrahimi N.A.	2017
36	A honey bee can threat ear: Sudden sensorineural hearing loss. ( 28818308 )	DA1zenli U....KA+roA9lu A.F.	2017
37	Idiopathic sudden sensorineural hearing loss and mAcniA"re syndrome: The role of cerebral venous drainage. ( 28744995 )	Ciccone M.M....Quaranta N.	2017
38	Early cortical metabolic rearrangement related to clinical data in idiopathic sudden sensorineural hearing loss. ( 28460253 )	Micarelli A....Alessandrini M.	2017
39	Differences in platelet-related parameters among patients with audiographically distinct sudden sensorineural hearing loss: A retrospective study. ( 28885341 )	Sun Y....Yin S.	2017
40	Factors Prognostic of Season-Associated Sudden Sensorineural Hearing Loss: A Retrospective Observational Study. ( 28417108 )	Ryu I.Y....Yeo S.G.	2017
41	Use of Vasodilators In Idiopathic Sudden Sensorineural Hearing Loss: A Systematic Review. ( 29283102 )	Bravenboer de Sousa M....Thomeer H.	2017
42	Early identification of idiopathic sudden sensorineural hearing loss. ( 28787350 )	Jensen E.A.H....Smith W.	2017
43	Sealing of the round and oval window niches with triamcinolone-soaked fascia as salvage surgical therapy in sudden sensorineural hearing loss. ( 28415914 )	Loader B....Lill C.	2017
44	Aminophylline restores glucocorticoid sensitivity in a guinea pig model of sudden sensorineural hearing loss induced by lipopolysaccharide. ( 28578424 )	Zhou Q.Q....She W.D.	2017
45	Questionnaires in Patients with Unilateral Sudden Sensorineural Hearing Loss. ( 28816692 )	Hwang G.H....Choi J.	2017
46	Assessment of balance and vestibular functions in patients with idiopathic sudden sensorineural hearing loss. ( 28397037 )	Liu J....Kong W.J.	2017
47	Adjunctive hyperbaric oxygen treatment for idiopathic sudden sensorineural hearing loss. ( 28768087 )	Chin C.S....Wu M.F.	2017
48	Identification of evidence for autoimmune pathology of bilateral sudden sensorineural hearing loss using proteomic analysis. ( 28648633 )	Lee J.M....Kim S.H.	2017
49	Framingham Risk Score as a Prognostic Predictor of Sudden Sensorineural Hearing Loss: A Preliminary Study. ( 28397567 )	Chang Y.S....Chung W.H.	2017
50	Erythrocyte Membrane Fluidity Alterations in Sudden Sensorineural Hearing Loss Patients: The Role of Oxidative Stress. ( 29212121 )	Becatti M....Fiorillo C.	2017

Sources

Genes for Sudden Sensorineural Hearing Loss

Genes related to Sudden Sensorineural Hearing Loss (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	F5	Coagulation Factor V	Protein Coding	18.42	GeneCards inferred via : Publications (show sections)
2	MTHFR	Methylenetetrahydrofolate Reductase	Protein Coding	18.35	GeneCards inferred via : Publications (show sections)
3	F2	Coagulation Factor II, Thrombin	Protein Coding	18.35	GeneCards inferred via : Publications (show sections)
4	SERPINC1	Serpin Family C Member 1	Protein Coding	17.73	GeneCards inferred via : Publications (show sections)
5	IL6	Interleukin 6	Protein Coding	17.73	GeneCards inferred via : Publications (show sections)
6	ITGB3	Integrin Subunit Beta 3	Protein Coding	17.73	GeneCards inferred via : Publications (show sections)

Sources

Variations for Sudden Sensorineural Hearing Loss

Sources

Expression for Sudden Sensorineural Hearing Loss

Search GEO for disease gene expression data for Sudden Sensorineural Hearing Loss.

Sources

Pathways for Sudden Sensorineural Hearing Loss

Pathways related to Sudden Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Response to elevated platelet cytosolic Ca2+ ⁶⁶ Show member pathways Disinhibition of SNARE formation ⁶⁶ Hemostasis ⁶⁶ Platelet activation, signaling and aggregation ⁶⁶ Platelet degranulation ⁶⁶	12.78	F2 F5 ITGB3 SERPINC1
2	Collagen chain trimerization ⁶⁶ Show member pathways Anchoring fibril formation ⁶⁶ Assembly of collagen fibrils and other multimeric structures ⁶⁶ Blood Coagulation Cascade ⁶⁴ Collagen biosynthesis and modifying enzymes ⁶⁶ Collagen formation ⁶⁶ Crosslinking of collagen fibrils ⁶⁶ Intrinsic Prothrombin Activation Pathway ⁶⁴ Protein digestion and absorption ³⁷	12.33	F2 F5 SERPINC1
3	Folate Metabolism ¹ Show member pathways Selenium Micronutrient Network ¹ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	11.66	F2 IL6 MTHFR
4	Formation of Fibrin Clot (Clotting Cascade) ⁶⁶ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁵ Common Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Prothrombin Activation Pathway ⁶⁴ Intrinsic Pathway of Fibrin Clot Formation ⁶⁶	11.33	F2 F5 SERPINC1
5	Platelet Aggregation Inhibitor Pathway, Pharmacodynamics ⁶¹	11.08	F2 ITGB3
6	Hematopoietic Stem Cell Differentiation ¹	11	IL6 ITGB3
7	Complement and coagulation cascades ¹ ³⁷	10.94	F2 F5 SERPINC1
8	Antifolate resistance ³⁷	10.75	IL6 MTHFR

Sources

GO Terms for Sudden Sensorineural Hearing Loss

Cellular components related to Sudden Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	endoplasmic reticulum lumen	GO:0005788	8.92	F2 F5 IL6 SERPINC1

Biological processes related to Sudden Sensorineural Hearing Loss according to GeneCards Suite gene sharing:

(show all 11)

#	Name	GO ID	Score	Top Affiliating Genes
1	post-translational protein modification	GO:0043687	9.65	F5 IL6 SERPINC1
2	platelet activation	GO:0030168	9.5	F2 IL6 ITGB3
3	positive regulation of peptidyl-tyrosine phosphorylation	GO:0050731	9.49	IL6 ITGB3
4	blood circulation	GO:0008015	9.46	F5 MTHFR
5	acute-phase response	GO:0006953	9.43	F2 IL6
6	positive regulation of JAK-STAT cascade	GO:0046427	9.4	F2 IL6
7	regulation of blood coagulation	GO:0030193	9.37	F2 SERPINC1
8	hemostasis	GO:0007599	9.33	F2 F5 SERPINC1
9	negative regulation of lipid storage	GO:0010888	9.26	IL6 ITGB3
10	cellular protein metabolic process	GO:0044267	9.26	F2 F5 IL6 SERPINC1
11	blood coagulation	GO:0007596	8.92	F2 F5 ITGB3 SERPINC1

Sources

Sources for Sudden Sensorineural Hearing Loss

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia