MCID: SLF016
MIFTS: 25

Sulfonamide Allergy

Categories: Immune diseases

Aliases & Classifications for Sulfonamide Allergy

Summaries for Sulfonamide Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger sulfonamide.

MalaCards based summary : Sulfonamide Allergy is related to severe cutaneous adverse reaction and exanthem. An important gene associated with Sulfonamide Allergy is EML2 (EMAP Like 2), and among its related pathways/superpathways are Metabolism and Serotonergic synapse. Affiliated tissues include skin, testes and heart.

Related Diseases for Sulfonamide Allergy

Graphical network of the top 20 diseases related to Sulfonamide Allergy:



Diseases related to Sulfonamide Allergy

Symptoms & Phenotypes for Sulfonamide Allergy

Drugs & Therapeutics for Sulfonamide Allergy

Search Clinical Trials , NIH Clinical Center for Sulfonamide Allergy

Genetic Tests for Sulfonamide Allergy

Anatomical Context for Sulfonamide Allergy

MalaCards organs/tissues related to Sulfonamide Allergy:

40
Skin, Testes, Heart, Tongue

Publications for Sulfonamide Allergy

Articles related to Sulfonamide Allergy:

(showing 40, show less)
# Title Authors PMID Year
1
Drug allergy is associated with the development of extraintestinal manifestations in patients with ulcerative colitis. 61
31594293 2020
2
Sulfonamide desensitization in solid organ transplant recipients: A protocol-driven approach during the index transplant hospitalization. 61
31596538 2019
3
Sulfonamide Allergies. 61
31514363 2019
4
Beta-Lactam and Sulfonamide Allergy Testing Should Be a Standard of Care in Immunocompromised Hosts. 61
31253580 2019
5
Dapsone safety in hematology patients: Pathways to optimizing Pneumocystis jirovecii pneumonia prophylaxis in hematology malignancy and transplant recipients. 61
30030892 2018
6
"Doctor, I have a Sulfa Allergy": Clarifying the Myths of Cross-Reactivity. 61
29959752 2018
7
Sulfonamide Drug Allergy. 61
29876667 2018
8
Desensitization to acetazolamide in a patient with previous antimicrobial sulfonamide allergy. 61
28089475 2017
9
[«Sulfonamide allergy» - which drugs must patients avoid?]. 61
27272369 2016
10
Implementation of a diuretic stewardship program in a pediatric cardiovascular intensive care unit to reduce medication expenditures. 61
26025996 2015
11
Skin rash induced by ritonavir-boosted darunavir is common, but generally tolerable in an observational setting. 61
24507978 2014
12
An evidence-based approach for providing cautionary recommendations to sulfonamide-allergic patients and determining cross-reactivity among sulfonamide-containing medications. 61
23489131 2013
13
[Sulfonamide allergy and cross-reactivity]. 61
23667968 2013
14
Successful treatment of cerebral toxoplasmosis with clindamycin: a case report. 61
23074553 2012
15
Ethacrynic acid as potential drug for diuretic renography in instance of sulfonamide allergy. 61
20548157 2010
16
Knowledge and attitudes of American pharmacists concerning sulfonamide allergy cross-reactivity. 61
20414726 2010
17
Acetazolamide and sulfonamide allergy: a not so simple story. 61
21190500 2010
18
Sulfonamide allergy and cross-reactivity. 61
17504660 2007
19
Sulfonamide allergy without cross-reactivity to celecoxib. 61
17156357 2007
20
The sulfone syndrome secondary to dapsone prophylaxis in a patient undergoing unrelated hematopoietic stem cell transplantation. 61
16639690 2006
21
Early-onset pentamidine-associated second-degree heart block and sinus bradycardia: case report and review of the literature. 61
15927910 2005
22
Sulfonamide cross-reactivity: fact or fiction? 61
15644481 2005
23
Leukocytoclastic vasculitis induced by use of glyburide: a case of possible cross-reaction of a sulfonamide and a sulfonylurea. 61
12661752 2003
24
Identification of sulfonamide-like adverse drug reactions to celecoxib in the World Health Organization database. 61
11900314 2001
25
Inhaled furosemide in the treatment of acute exacerbations of asthma 61
11015263 2000
26
Amprenavir: a new human immunodeficiency virus type 1 protease inhibitor. 61
10868554 2000
27
Antibiotic allergy in systemic lupus erythematosus: a case-control study. 61
1629825 1992
28
Allergic manifestations of human immunodeficiency virus (HIV) infection. 61
1676034 1991
29
[Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases]. 61
2084411 1990
30
Isospora belli infection: treatment with pyrimethamine. 61
3261956 1988
31
The management of patients with sulfonamide allergy. 61
3412290 1988
32
Trimethoprim-sulfamethoxazole for acute dysuria in women: a single-dose or 10-day course. A double-blind, randomized trial. 61
3257670 1988
33
Therapeutic equivalence of sulfaisodimidine 2 g twice daily and 1 g four times daily in lower urinary tract infections. 61
7051761 1982
34
Spontaneous formation of immunogenic conjugates by a biotransformation product of sulfanilamide. 61
6796976 1981
35
[Detection of sulfonamide allergy by means in vivo tests]. 61
4789830 1973
36
[On the causes of sulfonamide allergy of the skin]. 61
13819624 1960
37
[Sulfonamide allergy]. 61
12993468 1952
38
The pathology of sulfonamide allergy in man. 61
20991973 1946
39
The Pathology of Sulfonamide Allergy in Man. 61
19970888 1946
40
Sulfonamide Allergy. 61
18746741 1944

Variations for Sulfonamide Allergy

Expression for Sulfonamide Allergy

Search GEO for disease gene expression data for Sulfonamide Allergy.

Pathways for Sulfonamide Allergy

Pathways related to Sulfonamide Allergy according to GeneCards Suite gene sharing:

(showing 11, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.62 G6PD CYP2D6 CYP2C9 CA8 CA6 CA5A
2 11.54 CYP2D6 CYP2C9
3
Show member pathways
11.51 CYP2D6 CYP2C9
4
Show member pathways
11.44 CYP2D6 CYP2C9
5
Show member pathways
11.28 CYP2D6 CYP2C9
6
Show member pathways
11.17 CYP2D6 CYP2C9
7
Show member pathways
11.04 CYP2D6 CYP2C9
8
Show member pathways
10.85 CYP2D6 CYP2C9
9
Show member pathways
10.7 CYP2D6 CYP2C9
10
Show member pathways
10.49 CYP2D6 CYP2C9
11
Show member pathways
10.26 CA8 CA6 CA5A

GO Terms for Sulfonamide Allergy

Cellular components related to Sulfonamide Allergy according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.62 CYP2D6 CYP2C9

Biological processes related to Sulfonamide Allergy according to GeneCards Suite gene sharing:

(showing 13, show less)
# Name GO ID Score Top Affiliating Genes
1 lipid metabolic process GO:0006629 9.7 G6PD CYP2D6 CYP2C9
2 cholesterol metabolic process GO:0008203 9.51 CYP2D6 CYP2C9
3 xenobiotic metabolic process GO:0006805 9.49 CYP2D6 CYP2C9
4 bicarbonate transport GO:0015701 9.48 CA6 CA5A
5 arachidonic acid metabolic process GO:0019369 9.46 CYP2D6 CYP2C9
6 exogenous drug catabolic process GO:0042738 9.43 CYP2D6 CYP2C9
7 drug metabolic process GO:0017144 9.4 CYP2D6 CYP2C9
8 long-chain fatty acid biosynthetic process GO:0042759 9.37 CYP2D6 CYP2C9
9 organic acid metabolic process GO:0006082 9.32 CYP2D6 CYP2C9
10 estrogen metabolic process GO:0008210 9.26 CYP2D6 CYP2C9
11 oxidative demethylation GO:0070989 9.16 CYP2D6 CYP2C9
12 drug catabolic process GO:0042737 8.96 CYP2D6 CYP2C9
13 monoterpenoid metabolic process GO:0016098 8.62 CYP2D6 CYP2C9

Molecular functions related to Sulfonamide Allergy according to GeneCards Suite gene sharing:

(showing 6, show less)
# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.37 CYP2D6 CYP2C9
2 drug binding GO:0008144 9.32 CYP2D6 CYP2C9
3 monooxygenase activity GO:0004497 9.26 CYP2D6 CYP2C9
4 steroid hydroxylase activity GO:0008395 9.16 CYP2D6 CYP2C9
5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.96 CYP2D6 CYP2C9
6 carbonate dehydratase activity GO:0004089 8.8 CA8 CA6 CA5A

Sources for Sulfonamide Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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