MCID: SPR019
MIFTS: 20

Superficial Keratitis

Categories: Eye diseases

Aliases & Classifications for Superficial Keratitis

MalaCards integrated aliases for Superficial Keratitis:

Name: Superficial Keratitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:12196
ICD10 33 H16.10
ICD9CM 35 370.20
SNOMED-CT 68 193766004 27019000
UMLS 73 C0155074

Summaries for Superficial Keratitis

MalaCards based summary : Superficial Keratitis is related to philophthalmiasis and systemic lupus erythematosus. An important gene associated with Superficial Keratitis is CD44 (CD44 Molecule (Indian Blood Group)), and among its related pathways/superpathways are Adhesion and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include eye and endothelial.

Related Diseases for Superficial Keratitis

Diseases related to Superficial Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 philophthalmiasis 11.0
2 systemic lupus erythematosus 9.7
3 burns 9.7
4 dry eye syndrome 9.7
5 chlamydia 9.7
6 keratoconjunctivitis sicca 9.7
7 conjunctivitis 9.7
8 lupus erythematosus 9.7
9 keratoconjunctivitis 9.7
10 endotheliitis 9.7
11 mast cell disease 9.1 CD44 IFNA2
12 punctate epithelial keratoconjunctivitis 7.3 DHH IFNA2 PRPF6 SRCIN1 TNFRSF25

Graphical network of the top 20 diseases related to Superficial Keratitis:



Diseases related to Superficial Keratitis

Symptoms & Phenotypes for Superficial Keratitis

Drugs & Therapeutics for Superficial Keratitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical, Meibographic and Interferometric Evaluation of Phlyctenular Keratitis in Children - MEIBO-ROSACEE Recruiting NCT03479853

Search NIH Clinical Center for Superficial Keratitis

Genetic Tests for Superficial Keratitis

Anatomical Context for Superficial Keratitis

MalaCards organs/tissues related to Superficial Keratitis:

41
Eye, Endothelial

Publications for Superficial Keratitis

Articles related to Superficial Keratitis:

(show all 36)
# Title Authors Year
1
A novel herpesvirus associated with chronic superficial keratitis and proliferative conjunctivitis in a great horned owl (Bubo virginianus). ( 29656541 )
2018
2
Heat Shock Proteins 70kDa, Eosinophil Cationic Protein, and Nitric Oxide During Chronic Superficial Keratitis in Dogs. ( 28750792 )
2017
3
Inheritance of chronic superficial keratitis in Australian Greyhounds. ( 27147552 )
2016
4
A retrospective study of the occurrence of chronic superficial keratitis in 308 German Shepherd dogs: 1999-2010. ( 25286670 )
2014
5
Serum vascular endothelial growth factor concentration in dogs diagnosed with chronic superficial keratitis. ( 24334076 )
2013
6
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. ( 24238945 )
2013
7
Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. ( 23390756 )
2012
8
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. ( 21144596 )
2011
9
The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. ( 21521443 )
2011
10
Radiotherapy for canine chronic superficial keratitis using soft X-rays (15 kV). ( 20149171 )
2010
11
Major histocompatibility class II expression in the normal canine cornea and in canine chronic superficial keratitis. ( 16359362 )
2005
12
The effect of topical pimecrolimus on keratoconjunctivitis sicca and chronic superficial keratitis in dogs: results from an exploratory study. ( 15644099 )
2005
13
Efficacy and safety of 0.18% sodium hyaluronate in patients with moderate dry eye syndrome and superficial keratitis. ( 15965673 )
2005
14
Histological and immunohistochemical evaluation of canine chronic superficial keratitis. ( 10502491 )
1999
15
Comparison of topical cyclosporin and dexamethasone for the treatment of chronic superficial keratitis in dogs. ( 8693674 )
1995
16
Risk factors for development of chronic superficial keratitis in dogs. ( 8050943 )
1994
17
A case of severe symptomatic superficial keratitis associated with Epstein-Barr virus. ( 7958053 )
1994
18
Chronic superficial keratitis. ( 8451809 )
1993
19
Chronic superficial keratitis in German shepherd dogs. ( 1621351 )
1992
20
Proteoglycan-collagen interactions in chronic superficial keratitis in the dog. ( 1794491 )
1991
21
Immunohistochemical staining patterns of canine eyes affected with chronic superficial keratitis. ( 3767102 )
1986
22
Chronic superficial keratitis in a Mexican wolf. ( 4077662 )
1985
23
Superficial keratitis following solar eclipse burn (report of 6 cases). ( 7166419 )
1982
24
Superficial keratitis in dogs. ( 7290059 )
1981
25
Superficial keratitis. ( 6970603 )
1980
26
Superficial keratitis in treated systemic lupus erythematosus. ( 464504 )
1979
27
Corneal pannus (chronic superficial keratitis) in the German shepherd dog. ( 759720 )
1979
28
Chronic superficial keratitis (keratitis superficialis chronica) in the dog--I. A review of the literature. ( 642474 )
1978
29
Chronic superficial keratitis in the dog--II. Results of a combined non-surgical treatment. ( 642479 )
1978
30
Uberreiter's syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. ( 599907 )
1977
31
Chronic superficial keratitis. ( 584092 )
1977
32
Problem-oriented ophthalmology. Part 3. Chronic superficial keratitis. ( 979951 )
1976
33
Chronic superficial keratitis in dogs: detection of cellular hypersensitivity. ( 1169896 )
1975
34
Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia. ( 4348390 )
1973
35
Outbreak of superficial keratitis in rubber workers. ( 5347168 )
1969
36
Superficial keratitis due to plastic foreign bodies. ( 13605350 )
1959

Variations for Superficial Keratitis

Expression for Superficial Keratitis

Search GEO for disease gene expression data for Superficial Keratitis.

Pathways for Superficial Keratitis

Pathways related to Superficial Keratitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 CD44 SRCIN1
2 10.69 CD44 IFNA2

GO Terms for Superficial Keratitis

Sources for Superficial Keratitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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