MCID: SPR019
MIFTS: 25

Superficial Keratitis

Categories: Eye diseases

Aliases & Classifications for Superficial Keratitis

MalaCards integrated aliases for Superficial Keratitis:

Name: Superficial Keratitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:12196
ICD9CM 36 370.20
SNOMED-CT 69 27019000
ICD10 34 H16.10
UMLS 74 C0155074

Summaries for Superficial Keratitis

MalaCards based summary : Superficial Keratitis is related to philophthalmiasis and keratitis, hereditary. An important gene associated with Superficial Keratitis is CD44 (CD44 Molecule (Indian Blood Group)), and among its related pathways/superpathways are Cell adhesion molecules (CAMs) and Adhesion. Affiliated tissues include eye and endothelial.

Related Diseases for Superficial Keratitis

Diseases related to Superficial Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 philophthalmiasis 11.2
2 keratitis, hereditary 10.4
3 systemic lupus erythematosus 9.9
4 severe cutaneous adverse reaction 9.9
5 riboflavin deficiency 9.9
6 dry eye syndrome 9.9
7 chlamydia 9.9
8 keratoconjunctivitis sicca 9.9
9 conjunctivitis 9.9
10 lupus erythematosus 9.9
11 keratoconjunctivitis 9.9
12 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.9
13 punctate epithelial keratoconjunctivitis 9.4 DHH PRPF6 SRCIN1

Graphical network of the top 20 diseases related to Superficial Keratitis:



Diseases related to Superficial Keratitis

Symptoms & Phenotypes for Superficial Keratitis

Drugs & Therapeutics for Superficial Keratitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical, Meibographic and Interferometric Evaluation of Phlyctenular Keratitis in Children - MEIBO-ROSACEE Recruiting NCT03479853
2 Efficacy of T2259 in DED Not yet recruiting NCT03874429 Not Applicable

Search NIH Clinical Center for Superficial Keratitis

Genetic Tests for Superficial Keratitis

Anatomical Context for Superficial Keratitis

MalaCards organs/tissues related to Superficial Keratitis:

42
Eye, Endothelial

Publications for Superficial Keratitis

Articles related to Superficial Keratitis:

(show all 39)
# Title Authors Year
1
A novel herpesvirus associated with chronic superficial keratitis and proliferative conjunctivitis in a great horned owl (Bubo virginianus). ( 29656541 )
2019
2
A diagnosis of Stevens-Johnson Syndrome (SJS) in a patient presenting with superficial keratitis. ( 30128368 )
2018
3
Heat Shock Proteins 70kDa, Eosinophil Cationic Protein, and Nitric Oxide During Chronic Superficial Keratitis in Dogs. ( 28750792 )
2017
4
Inheritance of chronic superficial keratitis in Australian Greyhounds. ( 27147552 )
2016
5
Serum vascular endothelial growth factor concentration in dogs diagnosed with chronic superficial keratitis. ( 24334076 )
2014
6
A retrospective study of the occurrence of chronic superficial keratitis in 308 German Shepherd dogs: 1999-2010. ( 25286670 )
2014
7
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. ( 24238945 )
2013
8
Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. ( 23390756 )
2012
9
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. ( 21144596 )
2011
10
The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. ( 21521443 )
2011
11
Radiotherapy for canine chronic superficial keratitis using soft X-rays (15 kV). ( 20149171 )
2010
12
Efficacy and safety of 0.18% sodium hyaluronate in patients with moderate dry eye syndrome and superficial keratitis. ( 15965673 )
2005
13
The effect of topical pimecrolimus on keratoconjunctivitis sicca and chronic superficial keratitis in dogs: results from an exploratory study. ( 15644099 )
2005
14
Major histocompatibility class II expression in the normal canine cornea and in canine chronic superficial keratitis. ( 16359362 )
2005
15
Histological and immunohistochemical evaluation of canine chronic superficial keratitis. ( 10502491 )
1999
16
Comparison of topical cyclosporin and dexamethasone for the treatment of chronic superficial keratitis in dogs. ( 8693674 )
1995
17
A case of severe symptomatic superficial keratitis associated with Epstein-Barr virus. ( 7958053 )
1994
18
Risk factors for development of chronic superficial keratitis in dogs. ( 8050943 )
1994
19
Chronic superficial keratitis. ( 8451809 )
1993
20
Chronic superficial keratitis in German shepherd dogs. ( 1621351 )
1992
21
Proteoglycan-collagen interactions in chronic superficial keratitis in the dog. ( 1794491 )
1991
22
Immunohistochemical staining patterns of canine eyes affected with chronic superficial keratitis. ( 3767102 )
1986
23
Chronic superficial keratitis in a Mexican wolf. ( 4077662 )
1985
24
Superficial keratitis following solar eclipse burn (report of 6 cases). ( 7166419 )
1982
25
Superficial keratitis in dogs. ( 7290059 )
1981
26
Superficial keratitis. ( 6970603 )
1980
27
Superficial keratitis in treated systemic lupus erythematosus. ( 464504 )
1979
28
Corneal pannus (chronic superficial keratitis) in the German shepherd dog. ( 759720 )
1979
29
Chronic superficial keratitis (keratitis superficialis chronica) in the dog--I. A review of the literature. ( 642474 )
1978
30
Chronic superficial keratitis in the dog--II. Results of a combined non-surgical treatment. ( 642479 )
1978
31
Chronic superficial keratitis. ( 584092 )
1977
32
Uberreiter's syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. ( 599907 )
1977
33
Problem-oriented ophthalmology. Part 3. Chronic superficial keratitis. ( 979951 )
1976
34
Chronic superficial keratitis in dogs: detection of cellular hypersensitivity. ( 1169896 )
1975
35
Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia. ( 4348390 )
1973
36
Outbreak of superficial keratitis in rubber workers. ( 5347168 )
1969
37
Superficial keratitis due to plastic foreign bodies. ( 13605350 )
1959
38
Superficial Keratitis Due to Riboflavin Deficiency. ( 29012565 )
1942
39
Further Experience of the Treatment of Superficial Keratitis with Riboflavin. ( 29012582 )
1942

Variations for Superficial Keratitis

Expression for Superficial Keratitis

Search GEO for disease gene expression data for Superficial Keratitis.

Pathways for Superficial Keratitis

GO Terms for Superficial Keratitis

Biological processes related to Superficial Keratitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell receptor signaling pathway GO:0050852 9.32 CD4 HLA-DQA1
2 response to estradiol GO:0032355 9.26 CD4 DHH
3 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.16 CD4 CD44
4 interferon-gamma-mediated signaling pathway GO:0060333 8.96 CD44 HLA-DQA1
5 positive regulation of kinase activity GO:0033674 8.62 CD4 CD44

Sources for Superficial Keratitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....