MCID: SPR019
MIFTS: 23

Superficial Keratitis

Categories: Eye diseases

Aliases & Classifications for Superficial Keratitis

MalaCards integrated aliases for Superficial Keratitis:

Name: Superficial Keratitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:12196
ICD9CM 34 370.20
SNOMED-CT 67 27019000
ICD10 32 H16.10
UMLS 71 C0155074

Summaries for Superficial Keratitis

MalaCards based summary : Superficial Keratitis is related to dry eye syndrome and philophthalmiasis. An important gene associated with Superficial Keratitis is CD44 (CD44 Molecule (Indian Blood Group)). Affiliated tissues include eye, retina and testes.

Related Diseases for Superficial Keratitis

Diseases related to Superficial Keratitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 46, show less)
# Related Disease Score Top Affiliating Genes
1 dry eye syndrome 29.3 NGF LACRT CD44
2 philophthalmiasis 11.4
3 keratitis, hereditary 10.7
4 ocular hyperemia 10.3 PTGFR EVC2
5 serotonin syndrome 10.3 TAC1 IFNA2
6 prurigo nodularis 10.3 TAC1 NGF
7 detrusor sphincter dyssynergia 10.2 TAC1 NGF
8 cough variant asthma 10.2 TAC1 NGF
9 chronic cystitis 10.2 TAC1 NGF
10 trigeminal nerve disease 10.2 TAC1 NGF
11 mononeuropathy 10.2 TAC1 NGF
12 polyradiculopathy 10.2 TAC1 NGF
13 nerve compression syndrome 10.2 TAC1 NGF
14 burning mouth syndrome 10.2 TAC1 NGF
15 interval angle-closure glaucoma 10.2 TAC1 HLA-DQA1
16 sympathetic ophthalmia 10.1 HLA-DQA1 CD44
17 neurogenic bladder 10.1 TAC1 NGF
18 autoimmune disease 10.0
19 corneal disease 10.0
20 conjunctivitis 10.0
21 autonomic nervous system disease 10.0 TAC1 NGF
22 systemic lupus erythematosus 9.9
23 yemenite deaf-blind hypopigmentation syndrome 9.9
24 severe cutaneous adverse reaction 9.9
25 riboflavin deficiency 9.9
26 erythema multiforme 9.9
27 exanthem 9.9
28 corneal edema 9.9
29 chlamydia 9.9
30 allergic hypersensitivity disease 9.9
31 keratoconjunctivitis sicca 9.9
32 blepharospasm 9.9
33 eye disease 9.9
34 chickenpox 9.9
35 lupus erythematosus 9.9
36 pemphigus 9.9
37 keratoconjunctivitis 9.9
38 blepharitis 9.9
39 deep keratitis 9.9
40 erythema multiforme major 9.9
41 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.9
42 eyelid disease 9.8 SRCIN1 LACRT
43 onchocerciasis 9.7 SRCIN1 HLA-DQA1
44 corneal ulcer 9.7 NGF LACRT
45 keratopathy 9.6 TAC1 LACRT
46 punctate epithelial keratoconjunctivitis 8.7 TENT5D TAC1 SRCIN1 SBK1 PTGFR NGF

Graphical network of the top 20 diseases related to Superficial Keratitis:



Diseases related to Superficial Keratitis

Symptoms & Phenotypes for Superficial Keratitis

Drugs & Therapeutics for Superficial Keratitis

Interventional clinical trials:

(showing 1, show less)
# Name Status NCT ID Phase Drugs
1 Comparison of the Performance and Safety of T2259 Versus Vismed Multi in Dry Eye Patients With Superficial Keratitis. Recruiting NCT03874429

Search NIH Clinical Center for Superficial Keratitis

Genetic Tests for Superficial Keratitis

Anatomical Context for Superficial Keratitis

MalaCards organs/tissues related to Superficial Keratitis:

40
Eye, Retina, Testes, Endothelial

Publications for Superficial Keratitis

Articles related to Superficial Keratitis:

(showing 130, show less)
# Title Authors PMID Year
1
Frontalis Linkage Without Intraoperative Eyelid Elevation for the Management of Myopathic Ptosis. 61
31809486 2019
2
Utility of HSV Serology for Chronic Corneal Pathology. 61
31306215 2019
3
A novel herpesvirus associated with chronic superficial keratitis and proliferative conjunctivitis in a great horned owl (Bubo virginianus). 61
29656541 2019
4
A diagnosis of Stevens-Johnson Syndrome (SJS) in a patient presenting with superficial keratitis. 61
30128368 2018
5
Punctal Plug as a Treatment Option for Dry Eye Associated with Congenital Supernumary Puncta. 61
30765958 2018
6
Evaluation of a new matrix regenerating agent in patients with Sjögren syndrome and superficial ulcerative keratitis resistant to conventional therapy: A report of 3 cases. 61
29517701 2018
7
Comparison of Efficacy and Ocular Surface Disease Index Score between Bimatoprost, Latanoprost, Travoprost, and Tafluprost in Glaucoma Patients. 61
29707390 2018
8
Use of Copaifera multijuga for acute corneal repair after chemical injury: A clinical, histopathological and toxicogenetic study. 61
29169733 2017
9
Heat Shock Proteins 70kDa, Eosinophil Cationic Protein, and Nitric Oxide During Chronic Superficial Keratitis in Dogs. 61
28750792 2017
10
Inheritance of chronic superficial keratitis in Australian Greyhounds. 61
27147552 2016
11
Mini-Review: Limbal Stem Cells Deficiency in Companion Animals: Time to Give Something Back? 61
26287764 2016
12
Dendritiform Keratopathy Associated with Exposure to Polyquarternium-1, a Common Ophthalmic Preservative. 61
26686962 2016
13
[Clinical analyses of 21 cases of Thygeson's superficial punctate keratitis]. 61
26268638 2015
14
Adjunctive cryotherapy for pigmentary keratitis in dogs: a study of 16 corneas. 61
23953431 2014
15
Serum vascular endothelial growth factor concentration in dogs diagnosed with chronic superficial keratitis. 61
24334076 2014
16
Non-contact lens use-related Acanthamoeba keratitis in southern Turkey: evaluation of risk factors and clinical features. 61
24030538 2014
17
A retrospective study of the occurrence of chronic superficial keratitis in 308 German Shepherd dogs: 1999-2010. 61
25286670 2014
18
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. 61
24238945 2013
19
Ocular manifestations of small-vessel vasculitis. 61
23203643 2012
20
Microsporidial keratitis: Literature review and report of 2 cases in a tertiary eye care center. 61
23960992 2012
21
Clinical study on the application of tacrolimus and DMSO in the treatment of chronic superficial keratitis in dogs. 61
23390756 2012
22
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study. 61
21679090 2011
23
Adjuvant 5-fluorouracil in the treatment of localised ocular surface squamous neoplasia. 61
21252085 2011
24
Adenovirus advances: new diagnostic and therapeutic options. 61
21537185 2011
25
The effect of UV-blocking contact lenses as a therapy for canine chronic superficial keratitis. 61
21521443 2011
26
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. 61
21144596 2011
27
Primary central corneal hemangiosarcoma in a dog. 61
21366830 2011
28
Keratoprosthesis with retrocorneal fixation: preliminary results in dogs with corneal blindness. 61
20840104 2010
29
A keratoprosthesis prototype for the dog. 61
20149176 2010
30
Radiotherapy for canine chronic superficial keratitis using soft X-rays (15 kV). 61
20149171 2010
31
Penetrating keratoscleroplasty and bimodal grafting for treatment of limbal melanocytoma in a dog. 61
19046295 2008
32
Modulation of matrix metalloproteinases by ultraviolet radiation in the canine cornea. 61
18435653 2008
33
LASIK flap interface deposition in limbal vernal keratoconjunctivitis. 61
18271782 2008
34
[Applying the DNA diagnostics in patients with superficial keratitis of viral origin]. 61
18419101 2008
35
Immune-mediated canine and feline keratitis. 61
18299007 2008
36
Transcorneal electrical stimulation of retina to treat longstanding retinal artery occlusion. 61
17593383 2007
37
Archipelago keratitis: a clinical variant of recurrent herpetic keratitis? 61
17418418 2007
38
Acanthamoeba keratitis and contact lens wear. 61
17697181 2007
39
[Clinical forms of corneal abnormalities in atopic keratoconjunctivitis]. 61
18078059 2007
40
Histopathologic evidence of capecitabine corneal toxicity in dogs. 61
17846245 2007
41
[Treatment of ocular lesions due to Elapidae venom spitting in Central African Republic: epidemiological and clinical aspects]. 61
17727033 2007
42
Major histocompatibility class II expression in the normal canine cornea and in canine chronic superficial keratitis. 61
16359362 2005
43
An infant case of Graves' disease with ophthalmopathy. 61
16284447 2005
44
Efficacy and safety of 0.18% sodium hyaluronate in patients with moderate dry eye syndrome and superficial keratitis. 61
15965673 2005
45
A Korean case of Cornelia de Lange syndrome. 61
15988935 2005
46
Microsporidia: emerging ocular pathogens. 61
15928435 2005
47
[Pepper spray injuries of the anterior segment of the eye]. 61
15785998 2005
48
The effect of topical pimecrolimus on keratoconjunctivitis sicca and chronic superficial keratitis in dogs: results from an exploratory study. 61
15644099 2005
49
Trimethoprim-sulphamethoxazole therapy in Nocardia keratitis. 61
15281980 2004
50
In vivo confocal microscopy of Thygeson's superficial punctate keratitis. 61
15180847 2004
51
Vernal keratoconjunctivitis. 61
15069427 2004
52
Topical alpha-interferon in recurrent conjunctival papilloma. 61
12752062 2003
53
Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis infections in the cornea. 61
12484707 2002
54
[Corneal herpes: what's new?]. 61
12360698 2002
55
Keratitis. 61
11900320 2001
56
Histologic findings in a series of 1,540 corneal allografts. 61
11223555 2001
57
Comparison of the efficacy and safety of valaciclovir and acyclovir for the treatment of herpes zoster ophthalmicus. 61
10919899 2000
58
[Clinical experience with the preparation Uniflox Unimed Pharma in ophthalmology]. 61
10874794 2000
59
Histological and immunohistochemical evaluation of canine chronic superficial keratitis. 61
10502491 1999
60
A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap. 61
10201608 1999
61
[The efficacy of acyclovir treatment in the therapy of herpetic keratitis]. 61
11021286 1999
62
Acanthamoeba keratitis. 61
9635900 1998
63
Corneal injury from explosion of microwaved eggs. 61
9512160 1998
64
TNP-470 is an effective antimicrosporidial agent. 61
9466552 1998
65
Studies of canine leucocyte antigens: a significant advance in canine immunology. 61
9125354 1997
66
[Herpetic keratitis. Clinical and therapeutic aspects]. 61
15328644 1997
67
Comparison of topical cyclosporin and dexamethasone for the treatment of chronic superficial keratitis in dogs. 61
8693674 1995
68
Ultrastructural study of unidentified inclusions in the cornea and iridocorneal angle of dogs with pannus. 61
7653888 1995
69
The role of initial 5-fluorouracil trabeculectomy in primary glaucoma. 61
9136238 1994
70
Risk factors for development of chronic superficial keratitis in dogs. 61
8050943 1994
71
A case of severe symptomatic superficial keratitis associated with Epstein-Barr virus. 61
7958053 1994
72
Ganciclovir ophthalmic gel in herpes simplex virus rabbit keratitis: intraocular penetration and efficacy. 61
8083563 1994
73
Planned replacement of daily wear Acuvue disposable contact lenses. 61
8221291 1993
74
Chronic superficial keratitis. 61
8451809 1993
75
Investigation of antibodies to extractable nuclear antigens in dogs. 61
1626770 1992
76
Chronic superficial keratitis in German shepherd dogs. 61
1621351 1992
77
[Pathological and immunohistochemical evaluation of keratoepithelioplasty in rats]. 61
1553873 1992
78
Proteoglycan-collagen interactions in chronic superficial keratitis in the dog. 61
1794491 1991
79
[An analysis of 1,048 cases of corneal disease]. 61
2060399 1991
80
Cogan's syndrome. An unusual etiology of urticarial vasculitis. 61
1743387 1991
81
Determination of plasminogen activator activities in normal and pathological human tears. The significance of tear plasminogen activators in the inflammatory and traumatic lesions of the cornea and the conjunctiva. 61
2275342 1990
82
[Treatment of superficial herpes simplex keratitis with vidarabine (Vira A): multicenter study of 100 cases]. 61
2229899 1990
83
Toxic ulcerative keratopathy. An unrecognized problem. 61
2797722 1989
84
[Does a iatrogenic damage caused by dacryography exist?]. 61
2850599 1988
85
Treatment of periorbital Molluscum contagiosum by incision and curettage. 61
3399259 1988
86
Immunohistochemical staining patterns of canine eyes affected with chronic superficial keratitis. 61
3767102 1986
87
Ophthalmia neonatorum in Nairobi, Kenya: the roles of Neisseria gonorrhoeae and Chlamydia trachomatis. 61
3084664 1986
88
Monoclonal antibody analysis of blood and cornea T lymphocyte subpopulations in herpes simplex keratitis. 61
3485066 1986
89
Chronic superficial keratitis in a Mexican wolf. 61
4077662 1985
90
The serratial 56K protease as a major pathogenic factor in serratial keratitis. Clinical and experimental study. 61
3906492 1985
91
Application of immunoperoxidase staining in the cytodiagnosis of herpes simplex keratitis. 61
2424687 1985
92
Thymic factor therapy for herpetic keratitis. 61
3893286 1985
93
[Evaluation of 80 virologically-confirmed cases of ocular herpes. Study of the correlation between the type of virus and the epidemiologic characteristics of the disease]. 61
6323567 1983
94
Superficial keratitis following solar eclipse burn (report of 6 cases). 61
7166419 1982
95
The progression of the ocular abnormalities of herpes zoster. Histopathologic observations of nine cases. 61
6978475 1982
96
[Ocular herpes simplex in children (author's transl)]. 61
7054736 1982
97
Superficial keratitis in dogs. 61
7290059 1981
98
Thygeson's superficial punctate keratitis. 61
6264365 1981
99
[Arabinosyladenine in ophthalmology (author's transl)]. 61
7028853 1981
100
The use of a passive hemagglutination test (PHA) in the diagnosis of viral eye diseases. Investigation of lacrimal fluid for the presence of antibody to herpes simplex virus (HSV). 61
6905680 1980
101
Ocular findings in atopic dermatitis with special reference to the clinical features of atopic cataract. 61
7454225 1980
102
Superficial keratitis. 61
6970603 1980
103
[From superficial keratitis to deep keratitis: considerations on metaherpetic keratitis]. 61
6258675 1980
104
Superficial keratitis in treated systemic lupus erythematosus. 61
464504 1979
105
[Experience in therapy and prophylaxis of epidemic keratoconjunctivitis (author's transl)]. 61
480819 1979
106
Corneal pannus (chronic superficial keratitis) in the German shepherd dog. 61
759720 1979
107
Chronic superficial keratitis in the dog--II. Results of a combined non-surgical treatment. 61
642479 1978
108
Chronic superficial keratitis (keratitis superficialis chronica) in the dog--I. A review of the literature. 61
642474 1978
109
[Histological studies on the pathogenesis of chronic superficial keratitis (Ueberreiter) in the German sheppard]. 61
628829 1978
110
Uberreiter's syndrome (chronic superficial keratitis) in dogs in the Rocky Mountain area--a study of 463 cases. 61
599907 1977
111
[Herpetic eye diseases]. 61
195408 1977
112
Chronic superficial keratitis. 61
584092 1977
113
Problem-oriented ophthalmology. Part 3. Chronic superficial keratitis. 61
979951 1976
114
Chronic superficial keratitis in dogs: detection of cellular hypersensitivity. 61
1169896 1975
115
Chronic superficial keratitis in dogs: negative results of isolation procedures for Chlamydia. 61
4348390 1973
116
[Therapy of chronic superficial keratitis (Uberreiter) in the German sheep dog]. 61
4680180 1972
117
[Etiology of chronic superficial keratitis in German shepherd dogs]. 61
5171192 1971
118
[Therapy of dotted superficial keratitis]. 61
5461839 1970
119
Outbreak of superficial keratitis in rubber workers. 61
5347168 1969
120
[Thygeson's keratitis (16 cases of superficial keratitis punctata)]. 61
5760220 1968
121
[Studies on chronic superficial keratitis in the Alsatian]. 61
4972054 1968
122
[Discussion on the article "personal reflections on diffuse superficial keratitis"]. 61
6006875 1966
123
[Treatment of superficial keratitis with selenium]. 61
5990160 1966
124
Superficial keratitis due to plastic foreign bodies. 61
13605350 1959
125
[Superficial keratitis of the cornea in Favaloro's endothelitis]. 61
13479551 1957
126
[Superficial keratitis punctata following minor eye injuries]. 61
13383350 1956
127
[Superficial keratitis with temporary loss of epithelium]. 61
13307839 1955
128
[Intraepithelial punctate superficial keratitis following oral drug administration]. 61
13264498 1955
129
Further Experience of the Treatment of Superficial Keratitis with Riboflavin. 61
29012582 1942
130
Superficial Keratitis Due to Riboflavin Deficiency. 61
29012565 1942

Variations for Superficial Keratitis

Expression for Superficial Keratitis

Search GEO for disease gene expression data for Superficial Keratitis.

Pathways for Superficial Keratitis

GO Terms for Superficial Keratitis

Biological processes related to Superficial Keratitis according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.26 PTGFR NGF LACRT CD44
2 inflammatory response GO:0006954 8.92 TAC1 PTGFR IFNA2 CD44

Sources for Superficial Keratitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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