MCID: SPR020
MIFTS: 35

Superficial Mycosis

Categories: Infectious diseases, Skin diseases
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Aliases & Classifications for Superficial Mycosis

MalaCards integrated aliases for Superficial Mycosis:

Name: Superficial Mycosis 11 14 71 75
Piedra 11 43 71
Steroid-Modified Tinea Infection 11 71

Classifications:



External Ids:

Disease Ontology 11 DOID:0050133
MeSH 43 D010854
SNOMED-CT 68 266218008 47382004
ICD10 31 B36.9
UMLS 71 C0031898 C2980104 C3249878

Summaries for Superficial Mycosis

Disease Ontology: 11 A fungal infectious disease that results in infection of the outermost layer located in skin or located in hair shaft, has material basis in Fungi. No living tissue is invaded and there is no cellular response from the host.

MalaCards based summary: Superficial Mycosis, also known as piedra, is related to tinea nigra and white piedra. An important gene associated with Superficial Mycosis is TMC8 (Transmembrane Channel Like 8), and among its related pathways/superpathways are IL-1 Family Signaling Pathways and CLEC7A (Dectin-1) signaling. Affiliated tissues include skin, hair shaft and colon, and related phenotypes are Increased shRNA abundance (Z-score > 2) and immune system

Wikipedia: 75 A dermatomycosis is a skin disease caused by a fungus. This excludes... more...

Related Diseases for Superficial Mycosis

Diseases related to Superficial Mycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
# Related Disease Score Top Affiliating Genes
1 tinea nigra 32.0 POLR2B CBS
2 white piedra 31.8 POLR2B CLEC7A CBS
3 dermatophytosis 30.2 SQLE RNASE7 POLR2B CLEC7A CLEC6A CLEC4E
4 otomycosis 30.2 POLR2B CBS
5 fungal infectious disease 30.0 POLR2B CLEC7A CLEC6A CLEC4E CD4 CCR6
6 dermatomycosis 29.8 POLR2B CD4 CBS CARD9
7 pityriasis versicolor 29.5 ZNF347 TMC8 TMC6 RNASE7 RHOH CORO1A
8 tinea cruris 29.5 SQLE RNASE7 CLEC6A CBS CARD9
9 tinea corporis 28.8 SQLE RNASE7 CLEC7A CLEC6A CLEC4E CD4
10 tinea pedis 28.7 ZNF347 SQLE RNASE7 CLEC7A CLEC6A CD4
11 tinea capitis 28.6 SQLE POLR2B CLEC7A CLEC6A CLEC4E CD4
12 black piedra 11.1
13 angiokeratoma of fordyce 10.3 TMC8 TMC6
14 focal epithelial hyperplasia 10.3 TMC8 TMC6
15 plantar wart 10.3 TMC8 TMC6
16 immunodeficiency 11 10.3 CCR6 CARD9
17 acanthoma 10.3 TMC8 TMC6
18 whim syndrome 1 10.2 TMC8 TMC6 CCR6
19 coronin-1a deficiency 10.2 CORO1A CCR6
20 gastroduodenitis 10.2 CD4 CCR6
21 spongiotic dermatitis 10.2 CD4 CCR6
22 chancroid 10.2 CD4 CCR6
23 skin sarcoidosis 10.2 CD4 CCR6
24 anti-basement membrane glomerulonephritis 10.2 CD4 CCR6
25 mikulicz disease 10.2 CD4 CCR6
26 immunodeficiency 13 10.2 TMC8 CD4
27 autoimmune cholangitis 10.1 CD4 CCR6
28 aortitis 10.1 CD4 CCR6
29 farmer's lung 10.1 CD4 CCR6
30 sympathetic ophthalmia 10.1 CD4 CCR6
31 scleral disease 10.1 CD4 CCR6
32 evans' syndrome 10.1 CD4 CCR6
33 progressive relapsing multiple sclerosis 10.1 CD4 CCR6
34 tinea imbricata 10.1 CLEC7A CLEC6A CARD9
35 dacryoadenitis 10.1 CD4 CCR6
36 scabies 10.1 CD4 CCR6
37 iritis 10.1 CD4 CCR6
38 non-severe covid-19 10.1 CD4 CCR6
39 autoimmune vasculitis 10.1 CD4 CCR6
40 mite infestation 10.1 CD4 CCR6
41 polyclonal hypergammaglobulinemia 10.1 CD4 CCR6
42 pollen allergy 10.1 CD4 CCR6
43 pediculus humanus capitis infestation 10.1
44 lice infestation 10.1
45 autoimmune glomerulonephritis 10.1 CD4 CCR6
46 eumycotic mycetoma 10.1 POLR2B CBS CARD9
47 paronychia 10.1
48 egg allergy 10.1 CD4 CCR6
49 tuberculoid leprosy 10.1 CD4 CCR6
50 xerophthalmia 10.1 CD4 CCR6

Graphical network of the top 20 diseases related to Superficial Mycosis:



Diseases related to Superficial Mycosis

Symptoms & Phenotypes for Superficial Mycosis

GenomeRNAi Phenotypes related to Superficial Mycosis according to GeneCards Suite gene sharing:

25 (show all 25)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.78 CLEC7A
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.78 SLC30A1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-111 9.78 CBS CLEC7A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-112 9.78 CLEC7A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-119 9.78 CLEC7A
6 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.78 CLEC7A
7 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.78 CLEC7A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-139 9.78 SLC30A1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.78 CLEC7A
10 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.78 CLEC7A
11 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.78 SLC30A1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.78 CLEC7A
13 Increased shRNA abundance (Z-score > 2) GR00366-A-17 9.78 CBS
14 Increased shRNA abundance (Z-score > 2) GR00366-A-179 9.78 CLEC7A
15 Increased shRNA abundance (Z-score > 2) GR00366-A-184 9.78 POLR2B SLC30A1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.78 CLEC7A
17 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.78 CBS
18 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.78 SLC30A1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.78 CLEC7A
20 Increased shRNA abundance (Z-score > 2) GR00366-A-215 9.78 POLR2B SLC30A1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-3 9.78 CBS
22 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.78 CLEC7A SLC30A1
23 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.78 CBS
24 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.78 CLEC7A
25 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.78 CBS

MGI Mouse Phenotypes related to Superficial Mycosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.77 CARD9 CBS CCR6 CD4 CLEC4E CLEC6A
2 hematopoietic system MP:0005397 9.4 CARD9 CBS CCR6 CD4 CLEC4E CLEC6A

Drugs & Therapeutics for Superficial Mycosis

Search Clinical Trials, NIH Clinical Center for Superficial Mycosis

Cochrane evidence based reviews: piedra

Genetic Tests for Superficial Mycosis

Anatomical Context for Superficial Mycosis

Organs/tissues related to Superficial Mycosis:

FMA: Skin, Hair Shaft
MalaCards : Skin, Colon, Endothelial, Breast

Publications for Superficial Mycosis

Articles related to Superficial Mycosis:

(show top 50) (show all 404)
# Title Authors PMID Year
1
The first report of tinea nigra from Iran. 62
36276912 2022
2
Assessing parasite epidemiology in the epidemiological importance of Patagonian Late Holocene rockshelters using carnivore coprolites in the past: new data from Piedra Parada, Argentina. 62
35924600 2022
3
[Tinea capitis by Trichophyton tonsurans in a pediatric patient]. 62
35900962 2022
4
Antifungal efficacy of pure boron on yeast and mold isolates causing superficial mycosis. 62
36156555 2022
5
Terbinafine Resistant Trichophyton Indotineae Isolated in Patients With Superficial Dermatophyte Infection in Canadian Patients. 62
35144480 2022
6
Pathogen Analysis of Superficial Mucocutaneous Mycosis in a Tertiary A-level Hospital from 2007 to 2018. 62
35403954 2022
7
Update on dermatophytosis in Mashhad, Northeastern Iran, emergence of infection with Trichophyton persicum. 62
36092243 2022
8
Talaromyces stipitatus, a novel agent causing superficial mycosis in a diabetic patient from North India. 62
34536577 2022
9
First report of Clonostachys rosea causing root rot on garlic in Mexico. 62
35171642 2022
10
Trichophyton tonsurans in Chile: Genotyping in search of an origin. 62
34919706 2022
11
Antimycobacterial activity of acetone extract and isolated metabolites from folklore medicinal lichen Usnea laevis Nyl. against drug-sensitive and multidrug-resistant tuberculosis strains. 62
34536516 2022
12
White Piedra: An Uncommon Superficial Fungal Infection of Hair. 62
35118127 2022
13
Telltale signs of skin trespassers: Clues to superficial mycosis. 62
35146987 2022
14
[Tinea capitis: epidemiological study in Tunis from 2012 to 2020]. 62
35655683 2022
15
´╗┐Tadpole soup: Chinantec caldo de piedra and behavior of Duellmanohylaignicolor larvae (Amphibia, Anura, Hylidae). 62
35837580 2022
16
Annular infectious dermatoses. 62
34974106 2021
17
Multiplex RT-PCR provides improved diagnosis of skin and nail dermatophyte infections compared to microscopy and culture: a laboratory study and review of the literature. 62
34256251 2021
18
Deformation understanding in the Upper Paleozoic of Ventana Ranges at Southwest Gondwana Boundary. 62
34675340 2021
19
The Primate Cultural Significance Index: applications with Popoluca Indigenous people at Los Tuxtlas Biosphere Reserve. 62
34627320 2021
20
Superficial mycosis, at the site or distant to the surgical site, appears to predispose patients to bacterial periprosthetic joint infections. 62
34510963 2021
21
In Vivo Efficacy of Clove Essential Oil Ointment for Microsporum gallinae Avian Dermatophytosis-A Randomized Controlled Trial. 62
34699144 2021
22
Molecular identification of yeasts from the order Trichosporonales causing superficial infections. 62
33839018 2021
23
Combinatory Effect of ALA-PDT and Itraconazole Treatment for Trichosporon asahii. 62
33164224 2021
24
New Record of Bipolaris cynodontis: An Emerging Human Pathogen Causing Superficial Mycosis in North India. 62
34307477 2021
25
Efficacy of topical vs combined oral and topical antifungals in white piedra of the scalp. 62
33031603 2021
26
Water quality of streams associated with artisanal gold mining; Suárez, Department of Cauca, Colombia. 62
34141911 2021
27
Magnetic particles as new adsorbents for the reduction of phosphate inputs from a wastewater treatment plant to a Mediterranean Ramsar wetland (Southern Spain). 62
33757273 2021
28
Mother-daughter white piedra coinfection: a result of homemade hair cream use? 62
33319369 2021
29
Preparation of Topical Itraconazole with Enhanced Skin/Nail Permeability and In Vivo Antifungal Efficacy against Superficial Mycosis. 62
33925457 2021
30
Miconazole induces autophagic death in glioblastoma cells via reactive oxygen species-mediated endoplasmic reticulum stress. 62
33692867 2021
31
White Piedra. 62
33471028 2021
32
Impact of Auricular Neurostimulation in Patients Undergoing Colorectal Surgery with an Enhanced Recovery Protocol: A Pilot Randomized, Controlled Trial. 62
33417346 2021
33
Epidemiological Characterization of Dermatomycosis in Ethiopia. 62
33519223 2021
34
Analysis on the pathogenic fungi in patients with superficial mycosis in the Northeastern China during 10 years. 62
33209125 2020
35
Micromonospora fluminis sp. nov., isolated from mountain river sediment. 62
33174828 2020
36
Case Report: Extensive Tinea Corporis and Inflammatory Tinea Capitis Caused by the Anthropophilic Dermatophyte Trichophyton tonsurans. 62
32901593 2020
37
Cutaneous adverse-events in patients treated with Ibrutinib. 62
32790083 2020
38
Functional Defect of Neutrophils Causing Dermatophytosis: Case Report. 62
33105551 2020
39
Erratum to: The Piedra Chamana fossil woods and leaves: a record of the vegetation and palaeoenvironment of the Neotropics during the late Middle Eocene. 62
32839814 2020
40
Fusarium infections: Epidemiological aspects over 10 years in a university hospital in France. 62
32580917 2020
41
Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) Task Force against Recalcitrant Tinea (ITART) Consensus on the Management of Glabrous Tinea (INTACT). 62
32832435 2020
42
The Piedra Chamana fossil woods and leaves: a record of the vegetation and palaeoenvironment of the Neotropics during the late middle Eocene. 62
32161957 2020
43
Tinea Corporis-associated Erythroderma: Case Report and Review of Erythrodermic Patients with Chronic Dermatophyte Infection. 62
32391227 2020
44
Mixed Infection of Toe Nail Caused by Trichosporon asahii and Rhodotorula mucilaginosa. 62
31760556 2020
45
Image Gallery: White piedra. 62
31617200 2020
46
The adaptive response to iron involves changes in energetic strategies in the pathogen Candida albicans. 62
31788966 2020
47
Development of an Animal Model of Onychomycosis in Guinea Pigs. 62
33250504 2020
48
Atypical clinical presentation of an Arthroderma gypseum infection in a renal transplant recipient. 62
32578682 2020
49
Epidemiology of dermatophytic infections between 2008 and 2017 in Barcelona, Spain. 62
31076176 2019
50
Dermoscopy in the Evaluation of Pityriasis Versicolor: A Cross Sectional Study. 62
31807448 2019

Variations for Superficial Mycosis

Expression for Superficial Mycosis

Search GEO for disease gene expression data for Superficial Mycosis.

Pathways for Superficial Mycosis

Pathways related to Superficial Mycosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.81 CLEC7A CLEC6A CLEC4E CARD9
2
Show member pathways
11.33 CLEC7A CLEC6A CLEC4E CARD9

GO Terms for Superficial Mycosis

Biological processes related to Superficial Mycosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 10.06 CLEC7A CLEC6A CD4 CARD9
2 innate immune response GO:0045087 10.02 RNASE7 CORO1A CLEC7A CLEC6A CLEC4E CARD9
3 positive regulation of cytokine production GO:0001819 9.95 CLEC6A CLEC4E CARD9
4 immune system process GO:0002376 9.91 CLEC7A CLEC6A CLEC4E CD4 CARD9
5 T cell activation GO:0042110 9.8 CORO1A CLEC7A CD4
6 T cell migration GO:0072678 9.67 CORO1A CCR6
7 response to yeast GO:0001878 9.67 CLEC6A CLEC7A
8 thymocyte migration GO:0072679 9.56 CORO1A CCR6
9 detection of yeast GO:0001879 9.46 CLEC7A CLEC6A
10 biological process involved in interspecies interaction between organisms GO:0044419 9.43 CLEC6A CLEC4E
11 positive regulation of T-helper 17 type immune response GO:2000318 9.43 CLEC7A CLEC6A CARD9
12 antifungal innate immune response GO:0061760 9.23 CLEC7A CLEC6A CLEC4E CARD9

Molecular functions related to Superficial Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mechanosensitive monoatomic ion channel activity GO:0008381 9.26 TMC8 TMC6
2 pattern recognition receptor activity GO:0038187 9.1 CLEC7A CLEC6A CLEC4E

Sources for Superficial Mycosis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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