MCID: SPR020
MIFTS: 31

Superficial Mycosis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Superficial Mycosis

MalaCards integrated aliases for Superficial Mycosis:

Name: Superficial Mycosis 12 15 73
Piedra 12 44 73
Steroid-Modified Tinea Infection 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:0050133
ICD10 33 B36.9
MeSH 44 D010854
SNOMED-CT 68 47382004

Summaries for Superficial Mycosis

Disease Ontology : 12 A fungal infectious disease that results in infection of the outermost layer located in skin or located in hair shaft, has material basis in Fungi. No living tissue is invaded and there is no cellular response from the host.

MalaCards based summary : Superficial Mycosis, also known as piedra, is related to pityriasis versicolor and black piedra. An important gene associated with Superficial Mycosis is TMC8 (Transmembrane Channel Like 8). The drugs Fluconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include skin and skin or, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 76 A dermatomycosis is a skin disease caused by a fungus. This excludes... more...

Related Diseases for Superficial Mycosis

Diseases related to Superficial Mycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 pityriasis versicolor 31.0 KRT31 STIM1 TLR9 TMC6 TMC8
2 black piedra 11.5
3 white piedra 11.5
4 tinea nigra 11.5
5 tinea cruris 10.0
6 tinea corporis 10.0
7 dermatitis 10.0
8 pili torti 10.0
9 lipoid proteinosis of urbach and wiethe 10.0 TMC6 TMC8
10 epidermodysplasia verruciformis 9.9 TMC6 TMC8
11 tinea pedis 9.9
12 lichen planus 9.9

Graphical network of the top 20 diseases related to Superficial Mycosis:



Diseases related to Superficial Mycosis

Symptoms & Phenotypes for Superficial Mycosis

GenomeRNAi Phenotypes related to Superficial Mycosis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.23 CBS
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-119 9.23 CBS
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-141 9.23 CBS
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.23 CBS CIC
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.23 CIC
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.23 CIC
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.23 CIC

Drugs & Therapeutics for Superficial Mycosis

Drugs for Superficial Mycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
2
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 1 22916-47-8 4189
3
Micafungin Approved, Investigational Phase 3 235114-32-6 3081921 477468
4 Anti-Infective Agents Phase 3,Phase 1
5 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 1
6 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 1
7 Liver Extracts Phase 3
8 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
9 Steroid Synthesis Inhibitors Phase 3,Phase 1
10 Antifungal Agents Phase 3,Phase 1
11 Hormones Phase 3,Phase 1
12 Echinocandins Phase 3
13 Hormone Antagonists Phase 3,Phase 1
14 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
15
Itraconazole Approved, Investigational Phase 1 84625-61-6 55283
16
Hydroxyitraconazole Phase 1
17 Cytochrome P-450 CYP3A Inhibitors Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Micafungin Versus Fluconazole for Prevention of Invasive Fungal Disease in Living Donor Liver Transplant Recipients Unknown status NCT01974375 Phase 3 micafungin;Fluconazole
2 A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male Volunteers Completed NCT02493738 Phase 1 Lozanoc 50mg;Sporanox 100mg

Search NIH Clinical Center for Superficial Mycosis

Cochrane evidence based reviews: piedra

Genetic Tests for Superficial Mycosis

Anatomical Context for Superficial Mycosis

MalaCards organs/tissues related to Superficial Mycosis:

41
Skin

The Foundational Model of Anatomy Ontology organs/tissues related to Superficial Mycosis:

19
Skin Or

Publications for Superficial Mycosis

Articles related to Superficial Mycosis:

(show all 44)
# Title Authors Year
1
Superficial mycosis of the foot caused by Cladophialophora boppii. ( 29318642 )
2018
2
Neocucurbitaria keratinophila: An emerging opportunistic fungus causing superficial mycosis in Spain. ( 30496507 )
2018
3
Investigation of superficial mycosis in cutaneous allergy patients using topical or systemic corticosteroids. ( 28593694 )
2017
4
White piedra, black piedra, tinea versicolor, and tinea nigra: contribution to the diagnosis of superficial mycosis. ( 29186263 )
2017
5
Hydrochemical and isotopes studies in a hypersaline wetland to define the hydrogeological conceptual model: Fuente de Piedra Lake (Malaga, Spain). ( 27792952 )
2017
6
Generalized Superficial Mycosis Caused by Trichophyton raubitschekii in China: Case Report and Review of the Literature. ( 25502847 )
2015
7
Treatment of a superficial mycosis by low-temperature plasma: a case report. ( 24874937 )
2014
8
Superficial mycosis. ( 25742993 )
2014
9
Piedra: an ethnicity-related trichosis? ( 23786496 )
2014
10
Nodules on the hair: a rare case of mixed piedra. ( 24778538 )
2013
11
Comparison of superficial mycosis treatment using Butenafine and Bifonazole nitrate clinical efficacy. ( 23283047 )
2012
12
Inhibitory effect of essential oils against Trichosporon ovoides causing Piedra Hair Infection. ( 24031963 )
2012
13
Superficial mycosis and the immune response elements. ( 21987139 )
2011
14
Paleoparasitological finding of eggs of nematodes in rodent coprolites dated at the early Holocene from the archaeological site Cerro Casa de Piedra 7, Santa Cruz, Argentina. ( 21671716 )
2011
15
Study to compare the efficacy and safety of fluconazole cream with flutrimazole cream in the treatment of superficial mycosis: a multicentre, randomised, double-blind, phase III trial. ( 19558428 )
2010
16
Superficial mycosis of the breast caused by Curvularia inaequalis. ( 20627856 )
2010
17
Fumando la piedra: emerging patterns of crack use among Latino immigrant day laborers in New Orleans. ( 19924538 )
2010
18
Two cases of scalp white piedra caused by Trichosporon ovoides. ( 19439885 )
2009
19
White piedra in a mother and daughter. ( 20927238 )
2009
20
Marinobacter lacisalsi sp. nov., a moderately halophilic bacterium isolated from the saline-wetland wildfowl reserve Fuente de Piedra in southern Spain. ( 19542119 )
2009
21
Halobacillus alkaliphilus sp. nov., a halophilic bacterium isolated from a salt lake in Fuente de Piedra, southern Spain. ( 18398188 )
2008
22
Haloterrigena hispanica sp. nov., an extremely halophilic archaeon from Fuente de Piedra, southern Spain. ( 17625183 )
2007
23
Epidemiology of superficial mycosis (tinea pedis, onychomycosis) in elementary school children in Istanbul, Turkey. ( 16617585 )
2006
24
Alteromonas hispanica sp. nov., a polyunsaturated-fatty-acid-producing, halophilic bacterium isolated from Fuente de Piedra, southern Spain. ( 16280501 )
2005
25
Halomonas anticariensis sp. nov., from Fuente de Piedra, a saline-wetland wildfowl reserve in Malaga, southern Spain. ( 15280310 )
2004
26
Clinico-mycological Profile of Superficial Mycosis in a Hospital in North-East India. ( 27407482 )
2003
27
Superficial mycosis superimposing on isolated lichen planus of the lip: a case report and review of the literature. ( 12080952 )
2002
28
Guidelines of care for superficial mycotic infections of the skin: Piedra. Guidelines/Outcomes Committee. American Academy of Dermatology. ( 8543681 )
1996
29
A new Brevibacterium sp. isolated from infected genital hair of patients with white piedra. ( 8411085 )
1993
30
Superficial mycosis in renal transplant recipients. ( 2053155 )
1991
31
White piedra: ultrastructure and a new micro-ecological aspect. ( 29265561 )
1990
32
Comparative study of miconazole and clotrimazole in superficial mycosis. ( 2632381 )
1989
33
Piedra in a North Indian Woman. ( 28134206 )
1988
34
Yeasts in superficial mycosis : pathogenicity of Candida species to Swiss albino mice. ( 1010625 )
1976
35
Superficial mycosis in children of the Dominican Republic. ( 127118 )
1975
36
Yeasts in superficial mycosis. I. Incidence, isolation and characterisation. ( 1213721 )
1975
37
Morphology of Piedra hortal. ( 1162537 )
1975
38
White Piedra in India. ( 29160271 )
1970
39
Piedra-like artifacts. ( 13749379 )
1960
40
Piedra: report of a fifth case originating in the U.S.A. ( 13605282 )
1959
41
Piedra in Vermont. ( 13410122 )
1957
42
Piedra in mother and daughter. ( 13301059 )
1956
43
Piedra; report of a case. ( 14867918 )
1951
44
Culture of Fungus from Hairs affected with "Piedra.". ( 19975807 )
1912

Variations for Superficial Mycosis

Expression for Superficial Mycosis

Search GEO for disease gene expression data for Superficial Mycosis.

Pathways for Superficial Mycosis

GO Terms for Superficial Mycosis

Cellular components related to Superficial Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.26 STIM1 TLR9 TMC6 TMC8
2 endoplasmic reticulum membrane GO:0005789 8.92 STIM1 TLR9 TMC6 TMC8

Biological processes related to Superficial Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 8.8 STIM1 TMC6 TMC8

Molecular functions related to Superficial Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mechanosensitive ion channel activity GO:0008381 8.62 TMC6 TMC8

Sources for Superficial Mycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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