MCID: SPR033
MIFTS: 19

Superficial Spreading Melanoma

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Superficial Spreading Melanoma

MalaCards integrated aliases for Superficial Spreading Melanoma:

Name: Superficial Spreading Melanoma 54
Superficial Spreading Malignant Melanoma of Skin 74

Classifications:



External Ids:

UMLS 74 C0334438

Summaries for Superficial Spreading Melanoma

MalaCards based summary : Superficial Spreading Melanoma, also known as superficial spreading malignant melanoma of skin, is related to melanoma and lentigines. The drugs Cediranib and Maleic acid have been mentioned in the context of this disorder. Affiliated tissues include skin.

Wikipedia : 77 Superficial spreading melanoma (SSM) is usually characterized as the most common form of cutaneous... more...

Related Diseases for Superficial Spreading Melanoma

Diseases related to Superficial Spreading Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 melanoma 11.7
2 lentigines 10.3
3 nodular malignant melanoma 10.2
4 lentigo maligna melanoma 10.2
5 melanoma in congenital melanocytic nevus 10.1
6 mammary paget's disease 10.1
7 bowen's disease 10.1
8 basal cell carcinoma 1 9.9
9 psoriatic arthritis 9.9
10 arthritis 9.9
11 basal cell carcinoma 9.9
12 pigmented basal cell carcinoma 9.9
13 acral lentiginous melanoma 9.9
14 molluscum contagiosum 9.9
15 skin melanoma 9.9
16 spitz nevus 9.9

Graphical network of the top 20 diseases related to Superficial Spreading Melanoma:



Diseases related to Superficial Spreading Melanoma

Symptoms & Phenotypes for Superficial Spreading Melanoma

Drugs & Therapeutics for Superficial Spreading Melanoma

Drugs for Superficial Spreading Melanoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cediranib Investigational Phase 2 288383-20-0 9933475
2
Maleic acid Experimental, Investigational Phase 2 110-17-8, 110-16-7 444972
3 Protein Kinase Inhibitors Phase 2
4
Ganciclovir Approved, Investigational Phase 1 82410-32-0 3454
5 Anti-Infective Agents Phase 1
6 Antiviral Agents Phase 1
7 Nucleic Acid Synthesis Inhibitors Phase 1
8 Ganciclovir triphosphate Phase 1
9
Tyrosine Approved, Investigational, Nutraceutical Not Applicable 60-18-4 6057

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma Completed NCT00243061 Phase 2 cediranib maleate
2 Dinaciclib in Treating Patients With Stage IV Melanoma Active, not recruiting NCT00937937 Phase 2 Dinaciclib
3 Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma Terminated NCT01120275 Phase 2 gamma-secretase/Notch signalling pathway inhibitor RO4929097
4 Gene Therapy and Ganciclovir in Treating Patients With Stage IV Melanoma Completed NCT00005057 Phase 1 ganciclovir
5 cKIT, BRAF/NRAS Mutations in Advanced Melanoma : Clinical Outcome in Response to Tyrosine-kinase Inhibitors - KitMel Project Completed NCT01543113 Not Applicable
6 Sensitivity/Specificity Study of Non-invasive Imaging for Melanoma Diagnosis Completed NCT01556503
7 French Clinical Datbase of Melanoma Patients (RIC-Mel) Recruiting NCT03315468

Search NIH Clinical Center for Superficial Spreading Melanoma

Genetic Tests for Superficial Spreading Melanoma

Anatomical Context for Superficial Spreading Melanoma

MalaCards organs/tissues related to Superficial Spreading Melanoma:

42
Skin

Publications for Superficial Spreading Melanoma

Articles related to Superficial Spreading Melanoma:

(show top 50) (show all 61)
# Title Authors Year
1
Nevus Count Associations with Thinner Nodular or Superficial Spreading Melanoma. ( 30734046 )
2019
2
Fast-growing melanoma: a distinct entity or a superficial spreading melanoma with a brief horizontal phase? ( 30656767 )
2019
3
High density of M2-macrophages in acral lentiginous melanoma compared to superficial spreading melanoma. ( 29415335 )
2018
4
Association of Skin Examination Behaviors and Thinner Nodular vs Superficial Spreading Melanoma at Diagnosis. ( 29710122 )
2018
5
Nested Melanoma, a New Morphological Variant of Superficial Spreading Melanoma with Characteristic Dermoscopic Features. ( 28511756 )
2017
6
A single-institution assessment of superficial spreading melanoma (SSM) in the pediatric population: Molecular and histopathologic features compared with adult SSM. ( 28754310 )
2017
7
Nodular melanoma is less likely than superficial spreading melanoma to be histologically associated with a naevus. ( 29020904 )
2017
8
Pigmented basal cell carcinoma mimicking a superficial spreading melanoma. ( 28076343 )
2016
9
Superficial spreading melanoma in a psoriatic plaque of a patient with psoriatic arthritis. ( 27099025 )
2016
10
An assessment of clinical pathways and missed opportunities for the diagnosis of nodular melanoma versus superficial spreading melanoma. ( 26563931 )
2016
11
Superficial spreading melanoma: an analysis of 97 702 cases using the SEER database. ( 26926150 )
2016
12
Pigmented Mammary Paget Disease Mimicking Superficial Spreading Melanoma in an Elderly African-American Female. ( 25775646 )
2015
13
Abrupt Intralesional Color Change on Dermoscopy as a New Indicator of Early Superficial Spreading Melanoma in a Japanese Woman. ( 26269701 )
2015
14
Acral, Superficial Spreading Melanoma Arising on Melanocytic Nevus in a Pregnant Woman: A Case Report with Review. ( 26677279 )
2015
15
Polypoid melanoma and superficial spreading melanoma different subtypes in the same lesion. ( 25054761 )
2014
16
A case of a superficial spreading melanoma in situ diagnosed via digital dermoscopic monitoring with high dynamic range conversion. ( 25396087 )
2014
17
Outcomes and prognostic factors in superficial spreading melanoma. ( 24124662 )
2013
18
Risk factors for lentigo maligna melanoma compared with superficial spreading melanoma: a case-control study in Australia. ( 22004881 )
2012
19
Clinical and diagnostic features of in situ melanoma and superficial spreading melanoma: a hospital based study. ( 21371133 )
2012
20
Achromic superficial spreading melanoma accidentally treated with imiquimod. ( 21725584 )
2012
21
Histological and genetic evidence for a variant of superficial spreading melanoma composed predominantly of large nests. ( 22388759 )
2012
22
Superficial spreading melanoma. ( 22496298 )
2012
23
Automated detection of malignant features in confocal microscopy on superficial spreading melanoma versus nevi. ( 21198161 )
2010
24
Dermoscopy of Pigmented Bowen's Disease Mimicking Early Superficial Spreading Melanoma. ( 20652107 )
2009
25
Molluscum contagiosum arising in melanocytic nevus and in superficial spreading melanoma. ( 19278433 )
2009
26
Dermoscopy of superficial spreading melanoma. ( 19218911 )
2009
27
A case of sentinel node metastasis of superficial spreading melanoma with two lymphatic channels. ( 18258717 )
2008
28
Is superficial spreading melanoma still the most common form of malignant melanoma? ( 18485983 )
2008
29
Remodeling of the dermoepidermal junction in superficial spreading melanoma: insights gained from correlation of dermoscopy, reflectance confocal microscopy, and histopathologic analysis. ( 19075152 )
2008
30
Molecular cytogenetic characterization of a novel cell line established from a superficial spreading melanoma. ( 16368560 )
2006
31
Intratumoral DNA stem-line heterogeneity in superficial spreading melanoma. ( 15858470 )
2005
32
Only superficial spreading melanoma is causing the melanoma epidemics? ( 15012029 )
2004
33
Pathologic quiz case: a pigmented lesion on the chest of a 77-year-old man. Superficial spreading melanoma in vertical growth phase, with a microscopic satellite. ( 12873210 )
2003
34
Detection of nodular and superficial spreading melanoma with tumour thickness < or = 2.0 mm--an interview study. ( 11917208 )
2002
35
Lentigo maligna and superficial spreading melanoma are different in their in situ phase: an immunohistochemical study. ( 12395373 )
2002
36
Superficial spreading melanoma arising in a longstanding melanocytic nevus on the sole. ( 9640889 )
1998
37
Superficial spreading melanoma and blue naevus within naevus spilus--ultrastructural assessment of giant pigment granules. ( 9187835 )
1997
38
Primary malignant melanoma of the esophagus with diffuse pigmentation resembling superficial spreading melanoma. ( 9382074 )
1997
39
Detection of hyperdiploidy and chromosome breakage affecting the 1 (1cen-q12) region in lentigo malignant melanoma (LMM), superficial spreading melanoma (SSM) and congenital nevus (CN) cells in vitro by the multicolor FISH technique. ( 9461032 )
1997
40
Superficial spreading melanoma resembling Spitz nevus on the plantar surface. ( 8993968 )
1996
41
Tumor antigen expression in compound dysplastic nevi and superficial spreading melanoma defined by a panel of nevomelanoma monoclonal antibodies. ( 8743294 )
1996
42
A comparative immunohistochemical study of mammary and extramammary Paget's disease and superficial spreading melanoma, with particular emphasis on melanocytic markers. ( 8982382 )
1996
43
A case of superficial spreading melanoma in situ 2.5 mm in diameter. ( 8408926 )
1993
44
Natural history of a superficial spreading melanoma. ( 8486463 )
1993
45
Dysplastic nevi in relation to superficial spreading melanoma. ( 8467253 )
1993
46
The ultrastructure of dysplastic naevi: comparison with superficial spreading melanoma and common naevocellular naevi. ( 2260880 )
1990
47
Count of benign melanocytic nevi as a major indicator of risk for nonfamilial nodular and superficial spreading melanoma. ( 2369719 )
1990
48
Nucleolar organizer regions in superficial spreading melanoma with nodule. ( 2587571 )
1989
49
Superficial spreading melanoma with a nodular area: antigenic phenotype of the radial and vertical growth areas. ( 2711482 )
1989
50
Residual dysplastic and other nevi in superficial spreading melanoma. Clinical correlations and association with sun damage. ( 3383113 )
1988

Variations for Superficial Spreading Melanoma

Expression for Superficial Spreading Melanoma

Search GEO for disease gene expression data for Superficial Spreading Melanoma.

Pathways for Superficial Spreading Melanoma

GO Terms for Superficial Spreading Melanoma

Sources for Superficial Spreading Melanoma

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63 PubMed
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70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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