Aliases & Classifications for Suppression Amblyopia

MalaCards integrated aliases for Suppression Amblyopia:

Name: Suppression Amblyopia 12 15
Amblyopia 44 73
Amblyopia, Suppression 73
Strabismic Amblyopia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10375
ICD10 33 H53.03
ICD9CM 35 368.01
MeSH 44 D000550
SNOMED-CT 68 35600002

Summaries for Suppression Amblyopia

MalaCards based summary : Suppression Amblyopia, also known as amblyopia, is related to disuse amblyopia and mental and growth retardation with amblyopia, and has symptoms including photophobia, other specified visual disturbances and visual disturbance. An important gene associated with Suppression Amblyopia is GRM6 (Glutamate Metabotropic Receptor 6), and among its related pathways/superpathways are Circadian entrainment and cAMP signaling pathway. Affiliated tissues include eye, testes and pituitary, and related phenotypes are Decreased caspase 3/7 activity and behavior/neurological

Related Diseases for Suppression Amblyopia

Diseases related to Suppression Amblyopia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 disuse amblyopia 12.3
2 mental and growth retardation with amblyopia 12.0
3 microphthalmia, isolated 6 11.5
4 astigmatism 11.3
5 hemifacial hyperplasia with strabismus 11.3
6 isolated ectopia lentis 11.3
7 farsightedness 11.3
8 duane retraction syndrome 1 11.1
9 duane retraction syndrome 2 11.1
10 cerulean cataract 11.1
11 aniridia 1 10.9
12 aniridia and absent patella 10.9
13 cataract 41 10.9
14 fibrosis of extraocular muscles, congenital, 1 10.9
15 bornholm eye disease 10.9
16 fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement 10.9
17 corneal dystrophy, congenital stromal 10.9
18 mental retardation, anterior maxillary protrusion, and strabismus 10.9
19 cognitive impairment with or without cerebellar ataxia 10.9
20 duane retraction syndrome 3 with or without deafness 10.9
21 aniridia 2 10.9
22 paralytic squint 10.9
23 duane syndrome type 2 10.9
24 isolated duane retraction syndrome 10.9
25 anisometropia 10.6
26 refractive error 10.5
27 ptosis 10.4
28 amblyopia 10.4
29 mechanical strabismus 10.4
30 congenital ptosis 10.3
31 myopia 10.3
32 cataract 10.2
33 lacrimal duct defect 10.2
34 accommodative esotropia 10.2
35 ocular dominance 10.1
36 3-methylglutaconic aciduria, type iii 10.1
37 macular degeneration, age-related, 1 10.1
38 aniseikonia 10.1
39 monocular esotropia 10.1
40 ametropic amblyopia 10.1
41 esotropia 10.1
42 achromatopsia 10.0
43 strabismus 10.0
44 exotropia 10.0
45 optic nerve disease 10.0
46 color vision deficiency 10.0
47 cleft palate, isolated 9.9
48 optic nerve hypoplasia, bilateral 9.9
49 trigonocephaly 1 9.9
50 trigonocephaly 2 9.9

Graphical network of the top 20 diseases related to Suppression Amblyopia:



Diseases related to Suppression Amblyopia

Symptoms & Phenotypes for Suppression Amblyopia

UMLS symptoms related to Suppression Amblyopia:


photophobia, other specified visual disturbances, visual disturbance

GenomeRNAi Phenotypes related to Suppression Amblyopia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased caspase 3/7 activity GR00318-A 8.62 APTX GRIN1

MGI Mouse Phenotypes related to Suppression Amblyopia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.02 GABBR1 GRIN1 GRM6 HNMT NBL1

Drugs & Therapeutics for Suppression Amblyopia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old Completed NCT00669539
2 Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines Completed NCT03668067
3 AMblyopia Treatment Through PErceptual Training in Children (AMPEL) Not yet recruiting NCT02555384 Not Applicable

Search NIH Clinical Center for Suppression Amblyopia

Cochrane evidence based reviews: amblyopia

Genetic Tests for Suppression Amblyopia

Anatomical Context for Suppression Amblyopia

MalaCards organs/tissues related to Suppression Amblyopia:

41
Eye, Testes, Pituitary, Temporal Lobe, Brain, Retina, Cortex

Publications for Suppression Amblyopia

Articles related to Suppression Amblyopia:

(show top 50) (show all 353)
# Title Authors Year
1
Asymmetrical accommodation in hyperopic anisometropic amblyopia. ( 29051327 )
2018
2
Should tumbling E go out of date in amblyopia screening? Evidence from a population-based sample normative in children aged 3-4 years. ( 28988161 )
2018
3
New pediatric risk factors for amblyopia: strabismic versus refractive. ( 28967080 )
2018
4
Amblyopia and strabismus: trends in prevalence and risk factors among young adults in Israel. ( 28814414 )
2018
5
Dichoptic training in adults with amblyopia: Additional stereoacuity gains over monocular training. ( 28736224 )
2018
6
The use of rigid gas permeable contact lenses in children with myopic amblyopia: A case series. ( 28662862 )
2018
7
The effects of monocular training on binocular functions in anisometropic amblyopia. ( 28636883 )
2018
8
Patient-reported outcome measures in amblyopia and strabismus: a systematic review. ( 28636173 )
2018
9
Comparison of two methods for measuring contrast sensitivity in anisometropic amblyopia. ( 30555968 )
2018
10
ICL versus SMILE in management of anisometropic myopic amblyopia in children. ( 30502978 )
2018
11
Amblyopia therapy in Asian children: factors affecting visual outcome and parents' perception of children's attitudes towards amblyopia treatment. ( 30488078 )
2018
12
Factors related to amblyopia in congenital ptosis after frontalis sling surgery. ( 30463547 )
2018
13
Orientation Tuning and Contrast Dependence of Continuous Flash Suppression in Amblyopia and Normal Vision. ( 30452600 )
2018
14
Self-perception of School-Aged Children With Amblyopia and Its Association With Reading Speed and Motor Skills. ( 30452518 )
2018
15
Childhood Self-Perceptions in Children With Amblyopia: Is the Problem the Disease or the Treatment? ( 30452493 )
2018
16
Posterior chamber phakic intraocular lens for the correction of high myopic anisometropic amblyopia in adults. ( 30450321 )
2018
17
Prevalence of anterior polar cataracts in children and risk factors for amblyopia. ( 30390373 )
2018
18
Analysis of Macular Vessel Density and Foveal Avascular Zone Using Spectral-Domain Optical Coherence Tomography Angiography in Children With Amblyopia. ( 30371915 )
2018
19
Lamina cribrosa thickness in children with hyperopic anisometropic amblyopia. ( 30364189 )
2018
20
A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 7 to 12 Years of Age. ( 30352226 )
2018
21
Temporal frequency discrimination in amblyopia. ( 30344704 )
2018
22
Prevalence and Risk Factors of Amblyopia among Refractive Errors in an Eastern European Population. ( 30344237 )
2018
23
Postural stability and visual impairment: Assessing balance in children with strabismus and amblyopia. ( 30335817 )
2018
24
Atropine Penalization Versus Occlusion Therapies for Unilateral Amblyopia after the Critical Period of Visual Development: A Systematic Review. ( 30328078 )
2018
25
Prevalence of amblyopia in Bulgaria. ( 30325246 )
2018
26
A pilot study using electronic reminders for amblyopia treatment. ( 30325237 )
2018
27
A Novel Dichoptic Optokinetic Nystagmus Paradigm to Quantify Interocular Suppression in Monocular Amblyopia. ( 30304459 )
2018
28
Letter to editor: "is microtropia a reliable indicator for the presence of amblyopia in anisometropic patients?" by Lysons and Tapley. ( 30285526 )
2018
29
Evaluation of static and dynamic pupil characteristics in hyperopic anisometropic amblyopia. ( 30284453 )
2018
30
Visual acuity and amblyopia prevalence in 11- to 12-year-old Danish children from the Copenhagen Child Cohort 2000. ( 30280496 )
2018
31
Altered spontaneous brain activity patterns in strabismus with amblyopia patients using amplitude of low-frequency fluctuation: a resting-state fMRI study. ( 30275692 )
2018
32
Dichoptic Attentive Motion Tracking is Biased Toward the Nonamblyopic Eye in Strabismic Amblyopia. ( 30242356 )
2018
33
Effectiveness of binocularity-stimulating treatment in children with residual amblyopia following occlusion. ( 30236086 )
2018
34
Evaluation of retinal structure in unilateral amblyopia using spectral domain optical coherence tomography. ( 30218712 )
2018
35
Visual Search in Amblyopia: Abnormal Fixational Eye Movements and Suboptimal Sampling Strategies. ( 30208418 )
2018
36
The prevalence of amblyopia in Iran: A systematic review. ( 30197947 )
2018
37
Evaluation of a smartphone photoscreening app to detect refractive amblyopia risk factors in children aged 1-6 years. ( 30197499 )
2018
38
Effect of amblyopia treatment on choroidal thickness in hypermetropic anisometropic amblyopia using swept-source optical coherence tomography. ( 30170555 )
2018
39
Fluoxetine does not enhance the effect of perceptual learning on visual function in adults with amblyopia. ( 30150750 )
2018
40
Amblyopia: It is time to take action. ( 30127179 )
2018
41
Assessing amblyopia treatment using multifocal visual evoked potentials. ( 30103718 )
2018
42
Macular Thickness in Moderate to Severe Amblyopia. ( 30091310 )
2018
43
Is microtropia a reliable indicator of the presence of amblyopia in anisometropic patients? ( 30060696 )
2018
44
Global and regional estimates of prevalence of amblyopia: A systematic review and meta-analysis. ( 30059649 )
2018
45
Unilateral congenital nasolacrimal duct obstruction and amblyopia risk factors. ( 30050276 )
2018
46
Improvement of visual acuity in residual meridional amblyopia by astigmatic axis video games. ( 30038164 )
2018
47
OCT angiography findings in children with amblyopia. ( 30031875 )
2018
48
Longitudinal Evaluation of Accommodation During Treatment for Unilateral Amblyopia. ( 29801152 )
2018
49
New advances in amblyopia therapy I: binocular therapies and pharmacologic augmentation. ( 29777043 )
2018
50
Moebius Syndrome with Hypoglossal Palsy, Syndactyly, Brachydactyly, and Anisometropic Amblyopia. ( 29774172 )
2018

Variations for Suppression Amblyopia

Expression for Suppression Amblyopia

Search GEO for disease gene expression data for Suppression Amblyopia.

Pathways for Suppression Amblyopia

GO Terms for Suppression Amblyopia

Cellular components related to Suppression Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 presynaptic membrane GO:0042734 8.96 GABBR1 GRM6
2 dendrite GO:0030425 8.8 GABBR1 GRIN1 GRM6

Biological processes related to Suppression Amblyopia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 respiratory gaseous exchange GO:0007585 8.62 GRIN1 HNMT

Sources for Suppression Amblyopia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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