MCID: SPP003
MIFTS: 28

Suppurative Periapical Periodontitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Suppurative Periapical Periodontitis

MalaCards integrated aliases for Suppurative Periapical Periodontitis:

Name: Suppurative Periapical Periodontitis 12 15 73
Periapical Abscess 12 55 44
Suppurative Apical Periodontitis 12
Dentoalveolar Abscess 12
Apical Abscess 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2562
MeSH 44 D010482
NCIt 50 C34913
SNOMED-CT 68 34597006
ICD10 33 K04.6 K04.7
UMLS 73 C0031024

Summaries for Suppurative Periapical Periodontitis

MalaCards based summary : Suppurative Periapical Periodontitis, also known as periapical abscess, is related to dental abscess and periodontitis. An important gene associated with Suppurative Periapical Periodontitis is PIMREG (PICALM Interacting Mitotic Regulator). The drugs Doxycycline and Ciprofloxacin have been mentioned in the context of this disorder. Affiliated tissues include bone and heart.

Related Diseases for Suppurative Periapical Periodontitis

Diseases related to Suppurative Periapical Periodontitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 dental abscess 11.3
2 periodontitis 10.2
3 sinusitis 10.1
4 periapical periodontitis 10.1
5 maxillary sinusitis 10.0
6 burkitt lymphoma 10.0
7 hypochondroplasia 10.0
8 hypophosphatemic rickets, x-linked recessive 10.0
9 lymphoma 10.0
10 rickets 10.0
11 opioid abuse 9.9
12 chondroblastic osteosarcoma 9.9
13 periodontal disease 9.9
14 acute apical periodontitis 9.8

Graphical network of the top 20 diseases related to Suppurative Periapical Periodontitis:



Diseases related to Suppurative Periapical Periodontitis

Symptoms & Phenotypes for Suppurative Periapical Periodontitis

Drugs & Therapeutics for Suppurative Periapical Periodontitis

Drugs for Suppurative Periapical Periodontitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
2
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
3
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
4
Metronidazole Approved Phase 4 443-48-1 4173
5
Ethanol Approved Phase 4 64-17-5 702
6
Zinc Approved, Investigational Phase 4 7440-66-6
7
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
8
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 10909430 439542
9
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
10
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
11
Lactitol Investigational Phase 4 585-86-4 3871
12 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
13 Anti-Infective Agents, Local Phase 4,Phase 2,Phase 3
14 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
15 Anti-Infective Agents Phase 4,Phase 2,Phase 3
16 Propolis Phase 4
17 Antiprotozoal Agents Phase 4
18 Topoisomerase Inhibitors Phase 4
19 Bacitracin zinc, neomycin sulfate, polymyxin B, drug combination Phase 4
20 Polymyxins Phase 4
21 Polymyxin B Phase 4
22 Vasoconstrictor Agents Phase 4
23 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
24 Antiparasitic Agents Phase 4
25 Anesthetics Phase 4
26 Cytochrome P-450 Enzyme Inhibitors Phase 4
27 Antibiotics, Antitubercular Phase 4
28 Antitubercular Agents Phase 4
29 Bee Products Phase 4
30 Clindamycin palmitate Phase 4
31 Clindamycin phosphate Phase 4
32 Clavulanic Acids Phase 4
33 Amoxicillin-Potassium Clavulanate Combination Phase 4
34 beta-Lactamase Inhibitors Phase 4
35
Chlorhexidine Approved, Vet_approved Phase 2, Phase 3 55-56-1 2713 9552079
36 Neem Phase 2, Phase 3
37 Chlorhexidine gluconate Phase 2, Phase 3
38 Disinfectants Phase 2, Phase 3
39 Anti-Inflammatory Agents Phase 2, Phase 3,Not Applicable
40 Dermatologic Agents Phase 2, Phase 3
41 Root Canal Irrigants Phase 2, Phase 3
42
Tramadol Approved, Investigational Not Applicable 27203-92-5 33741
43
Codeine Approved, Illicit Not Applicable 76-57-3 5284371
44
Acetaminophen Approved Not Applicable 103-90-2 1983
45
Guaifenesin Approved, Investigational, Vet_approved Not Applicable 93-14-1 3516
46
Dexamethasone Approved, Investigational, Vet_approved Not Applicable 50-02-2 5743
47
Dexamethasone acetate Approved, Investigational, Vet_approved Not Applicable 1177-87-3
48 Analgesics Not Applicable
49 Antitussive Agents Not Applicable
50 Peripheral Nervous System Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old. Completed NCT03533231 Phase 4
2 AUGMENTIN™ in Dental Infections Completed NCT02141217 Phase 4 Amoxicillin/clavulanate;Clindamycin
3 Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy Unknown status NCT02943759 Phase 2, Phase 3 Neem leaf extract;Chlorhexidine gluconate
4 Systemic and Local Antimicrobials in the Management of Dental Abscess in Children Recruiting NCT03761264 Phase 2 Odontopaste®;Pulpdent;Amoxicillin
5 Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess Completed NCT02750696 Not Applicable Fixed-dose oral tablet of codeine/ acetaminophen every 4 hours for 3 days;Fixed-dose oral tablet of tramadol/ acetaminophen every 4 hours for 3 days
6 Periodontal and Periapical Inflammation and Pregnancy Completed NCT00490165
7 The Effects of Dexamethasone on the Time to Pain Resolution in Dental Periapical Abscess Recruiting NCT03005522 Not Applicable oral dexamethasone;Placebo Oral Capsule
8 Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations Enrolling by invitation NCT03514264 Not Applicable

Search NIH Clinical Center for Suppurative Periapical Periodontitis

Cochrane evidence based reviews: periapical abscess

Genetic Tests for Suppurative Periapical Periodontitis

Anatomical Context for Suppurative Periapical Periodontitis

MalaCards organs/tissues related to Suppurative Periapical Periodontitis:

41
Bone, Heart

Publications for Suppurative Periapical Periodontitis

Articles related to Suppurative Periapical Periodontitis:

(show all 40)
# Title Authors Year
1
Opioid abuse/dependence among those hospitalized due to periapical abscess. ( 30066389 )
2018
2
Fungal periapical abscess and the burn patient: A report of two cases of an unreported source for systemic infection. ( 28602586 )
2018
3
Capnocytophaga endodontalis sp. nov., Isolated from a Human Refractory Periapical Abscess. ( 29181783 )
2018
4
Chondroblastic osteosarcoma mimicking periapical abscess. ( 28877285 )
2017
5
Impact of Periapical Abscess on Infectious Complications in Patients Undergoing Extracorporeal Circulation Auxiliary to Open-Heart Surgical Procedures. ( 28259310 )
2017
6
Periapical abscess – etiology, pathogenesis and epidemiology ( 29186939 )
2017
7
A case of bacteremia caused by Dialister pneumosintes and Slackia exigua in a patient with periapical abscess. ( 26612007 )
2016
8
Analysis of Interleukin 17A in periapical abscess and granuloma lesions. ( 27050938 )
2016
9
A retrospective cohort study on the association between periapical abscess, advanced periodontal disease, and the national oral health screening program among Korean adults. ( 22186394 )
2013
10
Outcomes of hospitalizations attributed to periapical abscess from 2000 to 2008: a longitudinal trend analysis. ( 23953280 )
2013
11
Draft Genome Sequence of the Novel Peptoniphilus sp. Strain ChDC B134, Isolated from a Human Periapical Abscess Lesion. ( 24158551 )
2013
12
Nonsteroidal anti-inflammatory drugs misleading the diagnosis of periapical abscess. ( 22690058 )
2012
13
Periapical abscess. ( 21282676 )
2011
14
Traumatic bone cyst suggestive of a chronic periapical abscess: a case report. ( 21771187 )
2011
15
Outcomes in patients hospitalized for periapical abscess in the United States: an analysis involving the use of a nationwide inpatient sample. ( 20807911 )
2010
16
Outcomes in Patients Hospitalized for Periapical Abscess in the United States. ( 25547691 )
2010
17
Chronic temporal abscess resulting from a periapical abscess of the upper right first molar. ( 19329233 )
2009
18
Maxillary sinusitis and periapical abscess following periodontal therapy: a case report using three-dimensional evaluation. ( 16579714 )
2006
19
Periapical abscess formation and resolution adjacent to dental implants: a clinical report. ( 11208196 )
2001
20
An endodontic periapical abscess mimicking a deep periodontal pocket: a case report. ( 11324272 )
2000
21
Dentin malformation with alveolar bone loss and periapical abscess formation. ( 10197342 )
1999
22
Chronic factitial ulcer of chin cured by endodontic (root-canal) surgery for underlying periapical abscess. ( 10321619 )
1999
23
Aerobic and anaerobic microbiology of periapical abscess. ( 1945488 )
1991
24
Interpret your X-ray. Chronic periapical abscess. ( 3868656 )
1985
25
Effective one-visit therapy for the acute periapical abscess. ( 6596388 )
1984
26
Interpret your x-rays: periapical abscess. ( 6955385 )
1982
27
Intracranial complications of sinusitis in children. A sequela of periapical abscess. ( 7073175 )
1982
28
Metronidazole in the treatment of chronic periapical abscess. ( 6940020 )
1981
29
Bacteriology of acute periapical abscess in children. ( 6943273 )
1981
30
Management and treatment of an immunosuppressed patient with an active periapical abscess. ( 89663 )
1977
31
A case report of an unusual central incisor associated with a chronic periapical abscess. ( 1072804 )
1976
32
Normal pathways of infection resulting from acute periapical abscess of mandibular teeth. ( 1075114 )
1976
33
An unusual periapical abscess. ( 4518041 )
1973
34
Periapical abscess from dens in dente. ( 5280468 )
1971
35
Periapical abscess with intranasal fistula. ( 5288827 )
1971
36
Endodontic management of large periapical abscess. ( 5225994 )
1966
37
Occult periapical abscess: a case report. ( 13842722 )
1960
38
Periapical abscess. ( 13640868 )
1959
39
Isolation of a Bacillus anthracis-like organism from a periapical abscess. ( 18110516 )
1949
40
The periapical abscess. ( 18139253 )
1949

Variations for Suppurative Periapical Periodontitis

Expression for Suppurative Periapical Periodontitis

Search GEO for disease gene expression data for Suppurative Periapical Periodontitis.

Pathways for Suppurative Periapical Periodontitis

GO Terms for Suppurative Periapical Periodontitis

Sources for Suppurative Periapical Periodontitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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