MCID: SPR011
MIFTS: 30

Suprasellar Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Suprasellar Meningioma

MalaCards integrated aliases for Suprasellar Meningioma:

Name: Suprasellar Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7634
NCIt 50 C6776
UMLS 73 C1336535

Summaries for Suprasellar Meningioma

MalaCards based summary : Suprasellar Meningioma is related to alveolar periostitis and pituitary adenoma, and has symptoms including headache and seizures. An important gene associated with Suprasellar Meningioma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Signaling by GPCR and Development_Leptin signaling via JAK/STAT and MAPK cascades. Affiliated tissues include pituitary, bone and heart, and related phenotypes are Decreased viability in esophageal squamous lineage and Increased circadian period length

Related Diseases for Suprasellar Meningioma

Diseases related to Suprasellar Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 alveolar periostitis 10.5 MBL2 SLC9C1
2 pituitary adenoma 10.1
3 adenoma 10.1
4 urethral calculus 10.0 F2 KLK3
5 central nervous system germ cell tumor 10.0 GFAP POMC
6 thyroiditis 10.0 TRH TSHB
7 hypothyroidism, congenital, nongoitrous, 4 9.9 POMC TSHB
8 laryngeal tuberculosis 9.8 CDK9 POMC
9 pituitary hormone deficiency, combined, 2 9.8 POMC TSHB
10 prostate adenoid cystic carcinoma 9.8 KLK3 POMC
11 tuberculous epididymitis 9.8 KLK3 POMC
12 adenohypophysitis 9.8 POMC TRH
13 retinoblastoma 9.8
14 body mass index quantitative trait locus 1 9.8
15 pituitary apoplexy 9.8
16 optic neuritis 9.8
17 prostatitis 9.8
18 neuritis 9.8
19 bilateral retinoblastoma 9.8
20 cerebrospinal fluid leak 9.8
21 rosai-dorfman disease 9.8
22 empty sella syndrome 9.8 POMC TRH
23 hyperpituitarism 9.7 POMC TRH
24 functioning pituitary adenoma 9.7 POMC TRH
25 withdrawal disorder 9.7 KLK3 POMC
26 chromophobe adenoma 9.7 POMC TRH
27 pituitary-dependent cushing's disease 9.7 POMC TRH
28 endocrine organ benign neoplasm 9.7 POMC TRH
29 endogenous depression 9.6 POMC TRH
30 gynecomastia 9.6 KLK3 POMC
31 organ system benign neoplasm 9.6 POMC TRH
32 hyperprolactinemia 9.6 POMC TRH
33 cell type benign neoplasm 9.5 POMC TRH
34 pituitary adenoma, prolactin-secreting 9.4 POMC TRH
35 thyroid gland disease 9.4 POMC TRH TSHB
36 amenorrhea 9.3 POMC TRH
37 hypothyroidism 9.3 POMC TRH TSHB
38 urinary system disease 9.2 KLK3 POMC
39 acromegaly 9.0 POMC TRH

Graphical network of the top 20 diseases related to Suprasellar Meningioma:



Diseases related to Suprasellar Meningioma

Symptoms & Phenotypes for Suprasellar Meningioma

UMLS symptoms related to Suprasellar Meningioma:


headache, seizures

GenomeRNAi Phenotypes related to Suprasellar Meningioma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.43 POMC SLC9C1 TRH F2 GFAP KLK3
2 Increased circadian period length GR00213-A 8.8 TSHB CDK9 GFAP

Drugs & Therapeutics for Suprasellar Meningioma

Search Clinical Trials , NIH Clinical Center for Suprasellar Meningioma

Genetic Tests for Suprasellar Meningioma

Anatomical Context for Suprasellar Meningioma

MalaCards organs/tissues related to Suprasellar Meningioma:

41
Pituitary, Bone, Heart, Prostate

Publications for Suprasellar Meningioma

Articles related to Suprasellar Meningioma:

(show all 33)
# Title Authors Year
1
Contralateral Eyebrow Approach for Unilateral Suprasellar Meningioma. ( 29404257 )
2018
2
Lumbar Drains Decrease the Risk of Postoperative Cerebrospinal Fluid Leak Following Endonasal Endoscopic Surgery for Suprasellar Meningiomas in Patients With High Body Mass Index. ( 29253284 )
2018
3
'Coexisting pituitary adenoma and suprasellar meningioma-a coincidence or causation effect: report of two cases and review of the literature'. ( 28560021 )
2017
4
Resection of suprasellar meningioma through interhemispheric approach. ( 24902112 )
2014
5
Regaining vision from no perception of light after radiotherapy for a case of suprasellar meningioma. ( 25654001 )
2014
6
Twenty-nine cases of resection of suprasellar meningioma through small bone window: an interhemispheric approach. ( 24592141 )
2013
7
Visual loss from a pituitary mass: collision tumors of prostatic metastasis and suprasellar meningioma. ( 22847068 )
2013
8
Severe bradycardia during suprasellar meningioma resection. ( 22754454 )
2012
9
Suprasellar meningioma presenting with an altitudinal field defect. ( 21873066 )
2012
10
The Importance of Ophthalmic Signs in the Diagnosis of Suprasellar Meningioma - a case report. ( 25606155 )
2009
11
Isolated intracranial Rosai-Dorfman disease mimicking suprasellar meningioma: case report with review of the literature. ( 18831912 )
2008
12
Intra-suprasellar meningioma mimicking pituitary apoplexy. ( 15118889 )
2004
13
Craniotomy for suprasellar meningioma in a 28-week pregnant woman without fetal heart rate monitoring. ( 15197120 )
2004
14
Craniotomy for suprasellar meningioma during pregnancy: role of fetal monitoring. ( 15197113 )
2004
15
A suprasellar meningioma simulating atypical retrobulbar optic neuritis. ( 14768857 )
2003
16
Visual field deficit caused by vascular compression from a suprasellar meningioma: case report. ( 11950417 )
2002
17
Suprasellar meningioma subsequent to treatment for a pituitary adenoma: case report. ( 9131026 )
1997
18
Suprasellar meningioma and blindness: a unique experience in Saudi Arabia. ( 8607078 )
1996
19
Suprasellar meningioma with expression of glial fibrillary acidic protein: a peculiar variant. ( 8560989 )
1995
20
Spontaneous haemorrhage in a cavernoma associated with a suprasellar meningioma: an unusual post-operative complication. ( 8011186 )
1994
21
Association of suprasellar meningioma with pituitary adenoma. ( 2099063 )
1990
22
Suprasellar meningioma 47 years after bilateral retinoblastoma. ( 3364173 )
1988
23
Acute remitting visual loss after coronary artery bypass surgery caused by a suprasellar meningioma. ( 3499079 )
1987
24
Suprasellar meningioma with intrasellar extension simulating pituitary adenoma. Case report. ( 3675276 )
1987
25
Surgical management of suprasellar meningioma. Part 2: Prognosis for visual function following craniotomy. ( 6470774 )
1984
26
Surgical management of suprasellar meningioma. Part 1: The influence of tumor size, duration of symptoms, and microsurgery on surgical outcome in 101 consecutive cases. ( 6470773 )
1984
27
The suprasellar meningioma. A review of the literature and presentation of a series of 31 cases. ( 4356806 )
1973
28
Suprasellar meningioma containing metastatic carcinoma. Report of case. ( 13733931 )
1961
29
Suprasellar meningioma; report of an atypical case. ( 14943762 )
1952
30
Bone changes in cases of suprasellar meningioma. ( 12976170 )
1952
31
Suprasellar meningioma. Report of a case. ( 14846873 )
1951
32
Suprasellar meningioma; report of an atypical case. ( 14922433 )
1951
33
Suprasellar Meningioma: Report of an Atypical Case. ( 16693556 )
1951

Variations for Suprasellar Meningioma

Expression for Suprasellar Meningioma

Search GEO for disease gene expression data for Suprasellar Meningioma.

Pathways for Suprasellar Meningioma

Pathways related to Suprasellar Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.4 CDK9 F2 GFAP KLK3 POMC TRH
2
Show member pathways
10.43 POMC TRH
3 9.95 F2 KLK3

GO Terms for Suprasellar Meningioma

Cellular components related to Suprasellar Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 F2 KLK3 MBL2 POMC TSHB
2 extracellular region GO:0005576 9.43 F2 KLK3 MBL2 POMC TRH TSHB
3 secretory granule GO:0030141 8.8 KLK3 POMC TRH

Biological processes related to Suprasellar Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.5 POMC TRH TSHB
2 response to wounding GO:0009611 9.37 F2 GFAP
3 hormone-mediated signaling pathway GO:0009755 9.26 TRH TSHB
4 acute-phase response GO:0006953 9.16 F2 MBL2
5 peptide hormone processing GO:0016486 8.96 POMC TSHB
6 regulation of signaling receptor activity GO:0010469 8.92 F2 POMC TRH TSHB

Molecular functions related to Suprasellar Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.33 F2 MBL2 POMC
2 serine-type endopeptidase activity GO:0004252 9.13 F2 KLK3 MBL2
3 hormone activity GO:0005179 8.8 POMC TRH TSHB

Sources for Suprasellar Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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