MCID: SPR008
MIFTS: 44

Supratentorial Primitive Neuroectodermal Tumor

Categories: Rare diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Supratentorial Primitive Neuroectodermal Tumor

MalaCards integrated aliases for Supratentorial Primitive Neuroectodermal Tumor:

Name: Supratentorial Primitive Neuroectodermal Tumor 12 53 15 73
Ewings Sarcoma-Primitive Neuroectodermal Tumor 73
Peripheral Neuroectodermal Tumor 53
Primative Neuroectodermal Tumor 53
Supratentorial Pnet 12
Pnet 53

Classifications:



External Ids:

Disease Ontology 12 DOID:4791
NCIt 50 C6968
SNOMED-CT 68 39781001 699318007
UMLS 73 C1336538

Summaries for Supratentorial Primitive Neuroectodermal Tumor

MalaCards based summary : Supratentorial Primitive Neuroectodermal Tumor, also known as ewings sarcoma-primitive neuroectodermal tumor, is related to atypical teratoid rhabdoid tumor and medulloblastoma, and has symptoms including fever An important gene associated with Supratentorial Primitive Neuroectodermal Tumor is SYP (Synaptophysin), and among its related pathways/superpathways are Neuroscience and Tyrosine metabolism. The drugs Afinitor and Sutent have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and endothelial.

Related Diseases for Supratentorial Primitive Neuroectodermal Tumor

Diseases related to Supratentorial Primitive Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 atypical teratoid rhabdoid tumor 32.4 S100B SYP
2 medulloblastoma 30.3 NCAM1 RASSF1 S100B SYP
3 supratentorial primitive neuroectodermal tumors, childhood 12.4
4 ewing sarcoma 11.8
5 pancreatic neuroendocrine tumor 11.6
6 primitive neuroectodermal tumor of the cervix uteri 11.3
7 soft tissue peripheral neuroepithelioma 11.1
8 primitive neuroectodermal tumor of the corpus uteri 11.1
9 ewing's family of tumors 10.9
10 esophageal neuroendocrine tumor 10.6 NCAM1 SYP
11 ovarian large-cell neuroendocrine carcinoma 10.6 NCAM1 SYP
12 lung combined type small cell carcinoma 10.6 NCAM1 SYP
13 sensory organ benign neoplasm 10.6 NCAM1 SYP
14 gallbladder small cell carcinoma 10.6 NCAM1 SYP
15 cutaneous ganglioneuroma 10.6 NCAM1 SYP
16 extrahepatic bile duct adenocarcinoma 10.6 NCAM1 SYP
17 orbital cancer 10.6 NCAM1 SYP
18 pancreatic endocrine carcinoma 10.6 NCAM1 SYP
19 pancreatic serous cystadenoma 10.6 NCAM1 SYP
20 conventional angiosarcoma 10.6 NCAM1 SYP
21 endometrial small cell carcinoma 10.6 NCAM1 SYP
22 mediastinal cancer 10.6 NCAM1 SYP
23 primary hepatic neuroendocrine carcinoma 10.6 S100B SYP
24 angiomyoma 10.5 NCAM1 SYP
25 mixed type thymoma 10.5 S100B SYP
26 gastric squamous cell carcinoma 10.5 NCAM1 SYP
27 chordoid meningioma 10.5 S100B SYP
28 gastric small cell carcinoma 10.5 NCAM1 SYP
29 dysembryoplastic neuroepithelial tumor 10.5 S100B SYP
30 subependymoma 10.5 NCAM1 SYP
31 rosette-forming glioneuronal tumor 10.5 S100B SYP
32 cervical clear cell adenocarcinoma 10.5 NCAM1 SYP
33 melanotic neuroectodermal tumor 10.5 S100B SYP
34 spermatocele 10.5 NCAM1 SYP
35 angiocentric glioma 10.5 S100B SYP
36 pineocytoma 10.5 S100B SYP
37 monophasic synovial sarcoma 10.5 RASSF1 S100B
38 cervix small cell carcinoma 10.5 NCAM1 SYP
39 anaplastic ependymoma 10.5 S100B SYP
40 papillary ependymoma 10.5 S100B SYP
41 myxopapillary ependymoma 10.4 NCAM1 S100B
42 large cell neuroendocrine carcinoma 10.4 NCAM1 SYP
43 subependymal giant cell astrocytoma 10.4 S100B SYP
44 papilloma of choroid plexus 10.4 S100B SYP
45 mixed ductal-endocrine carcinoma 10.4 NCAM1 SYP
46 olfactory neuroblastoma 10.4 S100B SYP
47 adrenal rest tumor 10.4 NCAM1 SYP
48 cerebral primitive neuroectodermal tumor 10.4 S100B SYP
49 ganglioneuroma 10.4 NCAM1 SYP
50 perineurioma 10.4 NCAM1 S100B

Graphical network of the top 20 diseases related to Supratentorial Primitive Neuroectodermal Tumor:



Diseases related to Supratentorial Primitive Neuroectodermal Tumor

Symptoms & Phenotypes for Supratentorial Primitive Neuroectodermal Tumor

UMLS symptoms related to Supratentorial Primitive Neuroectodermal Tumor:


fever

Drugs & Therapeutics for Supratentorial Primitive Neuroectodermal Tumor

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Afinitor 18 49 EVEROLIMUS Novartis March 2009
2
Sutent 18 49 SUNITINIB MALATE Pfizer May 2011/ January 2006

Drugs for Supratentorial Primitive Neuroectodermal Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 209)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 135968-09-1
2
Etoposide Approved Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 33419-42-0 36462
3
Cisplatin Approved Phase 3,Phase 2,Phase 1,Not Applicable 15663-27-1 84093 441203 2767
4
Carboplatin Approved Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 41575-94-4 10339178 498142 38904
5
Dacarbazine Approved, Investigational Phase 2, Phase 3,Phase 1 4342-03-4 5351166
6
Vincristine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 2068-78-2, 57-22-7 5978
7
Methotrexate Approved Phase 3,Phase 2,Not Applicable 1959-05-2, 59-05-2 126941
8
Temozolomide Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 85622-93-1 5394
9
Thiotepa Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 52-24-4 5453
10
Cyclophosphamide Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable 50-18-0, 6055-19-2 2907
11
Melphalan Approved Phase 2, Phase 3,Phase 1,Not Applicable 148-82-3 4053 460612
12
Isotretinoin Approved Phase 3,Phase 1,Not Applicable 4759-48-2 5538 5282379
13
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
14
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 51-75-2 4033
15
Ifosfamide Approved Phase 3,Phase 2,Phase 1,Not Applicable 3778-73-2 3690
16
Topotecan Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 119413-54-6, 123948-87-8 60700
17
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
18
Cyproheptadine Approved Phase 3,Phase 2 129-03-3 2913
19
Histamine Approved, Investigational Phase 3,Phase 2 75614-87-8, 51-45-6 774
20
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
21
Donepezil Approved Phase 3,Early Phase 1 120014-06-4 3152
22
Ondansetron Approved Phase 3 99614-02-5 4595
23
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
24
Levoleucovorin Approved, Investigational Phase 3,Phase 2 68538-85-2
25
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Not Applicable 58-05-9 143 6006
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Not Applicable 59-30-3 6037
27 Trofosfamide Investigational Phase 2, Phase 3 22089-22-1
28 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
29
Doxil Approved June 1999 Phase 3,Phase 2 31703
30 Alkylating Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
31 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1,Not Applicable
32 Folic Acid Antagonists Phase 3,Phase 2,Not Applicable
33 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
34 Dermatologic Agents Phase 3,Phase 2,Phase 1,Not Applicable
35 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2,Not Applicable
36 Vitamin B Complex Phase 3,Phase 2,Not Applicable
37 Etoposide phosphate Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
38 Immunosuppressive Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
39 Protective Agents Phase 3,Phase 2,Phase 1,Not Applicable
40 Antirheumatic Agents Phase 3,Phase 2,Phase 1,Not Applicable
41 Antimetabolites Phase 3,Phase 2,Not Applicable
42 Antimetabolites, Antineoplastic Phase 3,Phase 2,Not Applicable
43 Antimitotic Agents Phase 3,Phase 2,Phase 1,Not Applicable
44 Antineoplastic Agents, Alkylating Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
45 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
46
Histamine Phosphate Phase 3,Phase 2 51-74-1 65513
47 Dexamethasone acetate Phase 3,Phase 2,Phase 1 1177-87-3
48
Isophosphamide mustard Phase 3,Phase 2,Phase 1,Not Applicable 0
49 Analgesics Phase 3,Phase 2
50 topoisomerase I inhibitors Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 116)
# Name Status NCT ID Phase Drugs
1 Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors Unknown status NCT00179803 Phase 2, Phase 3
2 Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children Unknown status NCT00749723 Phase 2, Phase 3 carboplatin;etoposide;temozolomide;thiotepa, carboplatin, etoposide;temozolomide, thiotepa;etoposide;trofosfamide/etoposide
3 Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors Unknown status NCT00392886 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide;methotrexate;temozolomide;thiotepa;vincristine sulfate
4 Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma Completed NCT00336024 Phase 3 etoposide;cyclophosphamide;cisplatin;carboplatin;thiotepa;methotrexate;leucovorin calcium;vincristine sulfate
5 Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor Completed NCT00006461 Phase 3 cisplatin;cyclophosphamide;vincristine sulfate;etoposide
6 Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS Completed NCT00003859 Phase 3 carboplatin;cyclophosphamide;etoposide;vincristine sulfate
7 Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy Completed NCT01346267 Phase 3
8 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
9 Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors Completed NCT00369785 Phase 3 donepezil hydrochloride;Placebo
10 Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma Recruiting NCT00392327 Phase 3 Vincristine Sulfate;Carboplatin;Cisplatin;Cyclophosphamide;Isotretinoin
11 Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor Active, not recruiting NCT00085202 Phase 3 cisplatin;cyclophosphamide;vincristine
12 Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Active, not recruiting NCT01231906 Phase 3 vincristine sulfate;doxorubicin hydrochloride;cyclophosphamide;ifosfamide;etoposide;topotecan hydrochloride
13 Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer Active, not recruiting NCT01987596 Phase 3
14 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
15 Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors Unknown status NCT00274911 Phase 2 cisplatin;lomustine;vincristine sulfate
16 Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors Unknown status NCT00281905 Phase 2 carboplatin;cisplatin;cyclophosphamide;methotrexate;vincristine sulfate
17 Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor Completed NCT00003211 Phase 2 amifostine trihydrate;cisplatin;cyclophosphamide;vincristine sulfate
18 Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma Completed NCT00006258 Phase 2 cisplatin;cyclophosphamide;etoposide;methotrexate;vincristine sulfate
19 Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor Completed NCT00047177 Phase 2 Oxaliplatin
20 Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET) Completed NCT01542736 Phase 2 Carboplatin;Vincristine
21 Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer Completed NCT00002466 Phase 2 cyclophosphamide;doxorubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
22 Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors Completed NCT00025077 Phase 2 carboplatin;cyclophosphamide;thiotepa
23 A Study of Pemetrexed in Children With Recurrent Cancer Completed NCT00520936 Phase 2 pemetrexed
24 A Five-Tier, Open-Label Study of IMC-A12 in Advanced Sarcoma Completed NCT00668148 Phase 2
25 Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma Completed NCT00006102 Phase 2 becatecarin
26 Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer Completed NCT00003309 Phase 2 cisplatin;cyclophosphamide;etoposide;vincristine sulfate
27 Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors Completed NCT00003203 Phase 2 carboplatin;cisplatin;cyclophosphamide;vincristine sulfate
28 Tipifarnib in Treating Young Patients With Recurrent or Progressive High-Grade Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, or Brain Stem Glioma Completed NCT00070525 Phase 2 tipifarnib
29 Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors Completed NCT00005952 Phase 1, Phase 2 temozolomide
30 Thiotepa Followed by Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Malignant Glioma Completed NCT00008008 Phase 2 cyclophosphamide;thiotepa
31 Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumors Completed NCT00003846 Phase 2 carboplatin;cyclophosphamide;thiotepa;vincristine sulfate
32 Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment Completed NCT00066248 Phase 2 cyproheptadine hydrochloride;megestrol acetate
33 Lobradimil and Carboplatin in Treating Children With Brain Tumors Completed NCT00019422 Phase 2 carboplatin;lobradimil
34 Vinorelbine in Treating Children With Recurrent or Refractory Cancers Completed NCT00003234 Phase 2 vinorelbine tartrate
35 Phenylacetate in Treating Children With Recurrent or Progressive Brain Tumors Completed NCT00003241 Phase 2 phenylacetate
36 Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors Completed NCT00002463 Phase 2 MOPP Regimen;Leucovorin Calcium;Mechlorethamine Hydrochloride;Methotrexate;Prednisone;Procarbazine Hydrochloride;Vincristine Sulfate
37 Docetaxel in Treating Children With Recurrent Solid Tumors Completed NCT00002825 Phase 2 docetaxel
38 Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer Completed NCT00014573 Phase 2 carmustine;cisplatin;cyclophosphamide;paclitaxel
39 Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Completed NCT00002752 Phase 1, Phase 2
40 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
41 Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors Completed NCT00629889 Phase 2 levetiracetam;pregabalin
42 Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer Active, not recruiting NCT00445965 Phase 2
43 Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma Active, not recruiting NCT01977677 Phase 1, Phase 2 temozolomide;plerixafor
44 Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma Active, not recruiting NCT00602667 Phase 2 Induction Chemotherapy;Low-Risk Therapy;High-Risk Therapy;Intermediate-Risk Therapy
45 Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma Active, not recruiting NCT00939770 Phase 1, Phase 2 crizotinib
46 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
47 A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720) Terminated NCT00617890 Phase 2
48 Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor Withdrawn NCT00003273 Phase 2 carboplatin;cisplatin;cyclophosphamide;etoposide;leucovorin calcium;methotrexate;temozolomide;thiotepa;vincristine sulfate
49 Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors Unknown status NCT00002647 Phase 1 verteporfin
50 Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma Unknown status NCT00360854 Phase 1 erlotinib hydrochloride

Search NIH Clinical Center for Supratentorial Primitive Neuroectodermal Tumor

Genetic Tests for Supratentorial Primitive Neuroectodermal Tumor

Anatomical Context for Supratentorial Primitive Neuroectodermal Tumor

MalaCards organs/tissues related to Supratentorial Primitive Neuroectodermal Tumor:

41
Brain, Bone, Endothelial, Bone Marrow, Spinal Cord, T Cells, Pineal

Publications for Supratentorial Primitive Neuroectodermal Tumor

Articles related to Supratentorial Primitive Neuroectodermal Tumor:

(show top 50) (show all 51)
# Title Authors Year
1
Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor. ( 29670360 )
2018
2
Outcome for children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor (CNS-PNET) - a retrospective analysis spanning 40 years of treatment. ( 28325133 )
2017
3
Treatment outcome and patterns of failure in patients of non-pineal supratentorial primitive neuroectodermal tumor: review of literature and clinical experience form a regional cancer center in north India. ( 25990846 )
2015
4
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children. ( 24470556 )
2014
5
Supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in adult. ( 24966562 )
2014
6
MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system . ( 24470553 )
2014
7
A supratentorial primitive neuroectodermal tumor presenting with intracranial hemorrhage in a 42-year-old man: a case report and review of the literature. ( 23537064 )
2013
8
Proton radiation therapy for pediatric medulloblastoma and supratentorial primitive neuroectodermal tumors: outcomes for very young children treated with upfront chemotherapy. ( 23790826 )
2013
9
Supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. ( 23095172 )
2012
10
Supratentorial primitive neuroectodermal tumor (PNET): an uncommon location. ( 22297899 )
2011
11
Supratentorial primitive neuroectodermal tumors of the central nervous system in adults: molecular and histopathologic analysis of 12 cases. ( 21378543 )
2011
12
Late complete remission of supratentorial primitive neuroectodermal tumor (CNS-PNET) after multiple relapses. ( 21113945 )
2011
13
Severe allergic reactions to thiol-based cytoprotective agents mesna and amifostine in a child with a supratentorial primitive neuroectodermal tumor. ( 21646919 )
2011
14
Treatment of a supratentorial primitive neuroectodermal tumor using magnetic resonance-guided laser-induced thermal therapy. ( 22044371 )
2011
15
Supratentorial primitive neuroectodermal tumor metastasis to the abdomen via a ventriculoperitoneal shunt. ( 20526591 )
2010
16
Reduced-dose craniospinal radiotherapy followed by high-dose chemotherapy and autologous stem cell rescue for children with newly diagnosed high-risk medulloblastoma or supratentorial primitive neuroectodermal tumor. ( 21120191 )
2010
17
Successful radiation therapy for supratentorial primitive neuroectodermal tumor and epidermolysis bullosa simplex. ( 19760773 )
2010
18
Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas. ( 20515335 )
2010
19
High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome. ( 19402050 )
2009
20
Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children. ( 19411854 )
2009
21
Lipomatous supratentorial primitive neuroectodermal tumor with glioblastomatous differentiation. ( 19118780 )
2009
22
Secondary supratentorial primitive neuroectodermal tumor following treatment of childhood osteosarcoma. ( 19434734 )
2009
23
Therapeutic Difficulty in a Case of Supratentorial Primitive Neuroectodermal Tumor Diagnosed during Pregnancy. ( 19242570 )
2009
24
A supratentorial primitive neuroectodermal tumor in an adult: a case report and review of the literature. ( 17713720 )
2008
25
High-dose chemotherapy and autologous stem cell rescue in children with newly diagnosed high-risk or relapsed medulloblastoma or supratentorial primitive neuroectodermal tumor. ( 17066462 )
2007
26
Supratentorial primitive neuroectodermal tumor during pregnancy. Case report. ( 17505462 )
2007
27
[Different hypermethylation status of RASSF1A in medulloblastoma and supratentorial primitive neuroectodermal tumor]. ( 17374234 )
2007
28
Long-term relapse-free survival with supratentorial primitive neuroectodermal tumor in an adult: a case report. ( 16528456 )
2006
29
High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors. ( 16783165 )
2006
30
Supratentorial primitive neuroectodermal tumor (sPNET). ( 16612986 )
2006
31
Role of radiotherapy in supratentorial primitive neuroectodermal tumor in young children: results of the German HIT-SKK87 and HIT-SKK92 trials. ( 16575007 )
2006
32
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells. ( 17016591 )
2006
33
Molecular genetics of supratentorial primitive neuroectodermal tumors and pineoblastoma. ( 16398467 )
2005
34
Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor. ( 15712180 )
2005
35
High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors. ( 15719272 )
2005
36
Supratentorial primitive neuroectodermal tumor in an aged patient--case report--. ( 16247240 )
2005
37
Secondary supratentorial primitive neuroectodermal tumor following irradiation in a patient with low-grade astrocytoma. ( 15661719 )
2005
38
Somatostatin receptor subtype 2 is expressed by supratentorial primitive neuroectodermal tumors of childhood and can be targeted for somatostatin receptor imaging. ( 15131035 )
2004
39
[Supratentorial primitive neuroectodermal tumor: report of a surgical case]. ( 15352632 )
2004
40
Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor. ( 15310781 )
2004
41
Patterns of failure in relation to radiotherapy fields in supratentorial primitive neuroectodermal tumor. ( 15001261 )
2004
42
Valproic acid induces differentiation of a supratentorial primitive neuroectodermal tumor. ( 15739631 )
2004
43
PTEN and DMBT1 homozygous deletion and expression in medulloblastomas and supratentorial primitive neuroectodermal tumors. ( 15547761 )
2004
44
A novel case of a CAT to AAT transversion in codon 179 of the p53 gene in a supratentorial primitive neuroectodermal tumor harbored by a young girl. Case report and review of the literature. ( 12837982 )
2003
45
Unusual aberration involving the short arm of chromosome 11 in an 8-month-old patient with a supratentorial primitive neuroectodermal tumor. ( 12606132 )
2003
46
Mediastinal T-cell lymphoma in a boy 7 years after treatment of supratentorial primitive neuroectodermal tumor. ( 12902924 )
2003
47
Feasibility of four consecutive high-dose chemotherapy cycles with stem-cell rescue for patients with newly diagnosed medulloblastoma or supratentorial primitive neuroectodermal tumor after craniospinal radiotherapy: results of a collaborative study. ( 11352962 )
2001
48
Cytogenetic and histopathologic studies of congenital supratentorial primitive neuroectodermal tumors: a case report. ( 11349224 )
2001
49
Supratentorial primitive neuroectodermal tumor in children: clinical features, treatment outcome and prognostic factors. ( 10447606 )
1999
50
A continuous cell line (KK-2) from a supratentorial primitive neuroectodermal tumor. ( 1323907 )
1992

Variations for Supratentorial Primitive Neuroectodermal Tumor

Expression for Supratentorial Primitive Neuroectodermal Tumor

Search GEO for disease gene expression data for Supratentorial Primitive Neuroectodermal Tumor.

Pathways for Supratentorial Primitive Neuroectodermal Tumor

GO Terms for Supratentorial Primitive Neuroectodermal Tumor

Cellular components related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 terminal bouton GO:0043195 9.16 SYP TH
2 neuronal cell body GO:0043025 9.13 DDC S100B TH
3 synaptic vesicle GO:0008021 8.8 DDC SYP TH

Biological processes related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 memory GO:0007613 9.51 S100B TH
2 cellular response to drug GO:0035690 9.49 DDC TH
3 cellular response to growth factor stimulus GO:0071363 9.48 DDC TH
4 regulation of neuronal synaptic plasticity GO:0048168 9.46 S100B SYP
5 multicellular organism aging GO:0010259 9.43 DDC TH
6 cellular response to alkaloid GO:0071312 9.4 DDC TH
7 dopamine biosynthetic process GO:0042416 9.37 DDC TH
8 catecholamine biosynthetic process GO:0042423 9.32 DDC TH
9 aminergic neurotransmitter loading into synaptic vesicle GO:0015842 9.26 DDC TH
10 response to pyrethroid GO:0046684 9.16 DDC TH
11 isoquinoline alkaloid metabolic process GO:0033076 8.96 DDC TH
12 phytoalexin metabolic process GO:0052314 8.62 DDC TH

Molecular functions related to Supratentorial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 amino acid binding GO:0016597 8.62 DDC TH

Sources for Supratentorial Primitive Neuroectodermal Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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