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MCID: SYN004
MIFTS: 27

Synovial Angioma

Categories: Cancer diseases, Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes
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Aliases & Classifications for Synovial Angioma

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MalaCards integrated aliases for Synovial Angioma:

Name: Synovial Angioma 12 15
Hemangioma of Synovium 12
Synovial Hemangioma 71

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:8274
NCIt 49 C6525
UMLS 71 C1336546
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Summaries for Synovial Angioma

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MalaCards based summary : Synovial Angioma, also known as hemangioma of synovium, is related to critical illness polyneuropathy and aspiration pneumonitis, and has symptoms including pain An important gene associated with Synovial Angioma is KCNIP4 (Potassium Voltage-Gated Channel Interacting Protein 4), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include bone.

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Related Diseases for Synovial Angioma

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Diseases related to Synovial Angioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)
# Related Disease Score Top Affiliating Genes
1 critical illness polyneuropathy 10.1 F3 CRP
2 aspiration pneumonitis 10.1 F3 CRP
3 thrombasthenia 10.0 F3 F2
4 endocarditis 10.0 F2 CRP
5 hantavirus hemorrhagic fever with renal syndrome 10.0 F3 CRP
6 retinal vein occlusion 10.0 F3 F2
7 orbital osteomyelitis 10.0 F2 CRP
8 small intestine diverticulitis 10.0 F2 CRP
9 autoimmune disease of blood 10.0 F3 CRP
10 papillary adenofibroma 10.0 F3 F2
11 angina pectoris 10.0 F3 CRP
12 femoral neuropathy 10.0 F3 F2
13 lateral sinus thrombosis 10.0 F3 F2
14 scrub typhus 10.0 F3 CRP
15 hematocele of tunica vaginalis testis 10.0 F2 CRP
16 giant hemangioma 10.0 F3 F2
17 intermediate coronary syndrome 10.0 F3 CRP
18 waterhouse-friderichsen syndrome 10.0 F3 F2
19 hemopneumothorax 10.0 F3 F2
20 gastric hemangioma 10.0 F3 F2
21 hepatic infarction 10.0 F3 F2
22 ascending cholangitis 10.0 F2 CRP
23 splenic abscess 10.0 F2 CRP
24 hemopericardium 10.0 F3 F2
25 cerebral sinovenous thrombosis 10.0 F3 F2
26 acalculous cholecystitis 10.0 F2 CRP
27 sagittal sinus thrombosis 10.0 F3 F2
28 abducens nerve disease 10.0 F2 CRP
29 pyoderma 10.0 F3 CRP
30 branch retinal artery occlusion 10.0 F2 CRP
31 cerebral falx meningioma 10.0 F3 F2
32 intracranial hypotension 10.0 F3 F2
33 splenic sequestration 10.0 F3 F2
34 acute cholangitis 10.0 F2 CRP
35 mastoiditis 10.0 F2 CRP
36 abdominal tuberculosis 10.0 F2 CRP
37 paralytic ileus 10.0 F2 CRP
38 carotid stenosis 10.0 F7 CRP
39 ileus 10.0 F2 CRP
40 hepatic coma 10.0 F3 F2
41 common bile duct disease 10.0 F2 CRP
42 pyuria 10.0 F2 CRP
43 central retinal artery occlusion 10.0 F2 CRP
44 acute hemorrhagic encephalitis 10.0 F3 F2
45 kwashiorkor 10.0 F2 CRP
46 pleural empyema 10.0 F2 CRP
47 hantavirus pulmonary syndrome 10.0 F3 F2
48 intracranial hypertension, idiopathic 10.0 F3 F2
49 intracranial hypertension 10.0 F3 F2
50 hemorrhoid 10.0 F2 CRP

Graphical network of the top 20 diseases related to Synovial Angioma:



Diseases related to Synovial Angioma
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Symptoms & Phenotypes for Synovial Angioma

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UMLS symptoms related to Synovial Angioma:


pain
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Drugs & Therapeutics for Synovial Angioma

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Search Clinical Trials , NIH Clinical Center for Synovial Angioma

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Genetic Tests for Synovial Angioma

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Anatomical Context for Synovial Angioma

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MalaCards organs/tissues related to Synovial Angioma:

40
Bone
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Publications for Synovial Angioma

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Articles related to Synovial Angioma:

(show top 50) (show all 107)
# Title Authors PMID Year
1
Synovial Hemangioma of the Wrist With Cystic Invasion of Trapezoid and Capitate Bones. 61
31153656 2020
2
Synovial hemangioma of the knee joint in pediatrics: our case series and review of literature. 61
30980138 2019
3
[Synovial Haemangioma of the Knee - Diagnosis by Magnetic Resonance Imaging]. 61
31734979 2019
4
Undiagnosed synovial hemangioma of the knee: a case report. 61
31311579 2019
5
[Arthroscopic for the treatment of synovial hemangioma in knee joint: a case report]. 61
30884937 2019
6
[Synovial hemangioma of knee joint: a case report]. 61
30583658 2018
7
Synovial hemangiomas of wrist and ankle joint: A report of two rare cases. 61
30303163 2018
8
Synovial Hemangioma of the Temporomandibular Joint: Case Report. 61
30365579 2018
9
Articular abnormalities that may mimic arthritis. 61
30451404 2018
10
Synovial Hemangioma of the Knee Management and Excellent Outcome 2 Years after Arthroscopic Synovectomy in a 25-year-old Male with a 20-year History. 61
29051872 2017
11
It's not what it looks like: challenges in diagnosis of synovial lesions of the knee joint. 61
26915005 2016
12
Synovial Hemangioma Presenting as a Painful Locked Knee A Case Report. 61
27815956 2016
13
Case Report of Mimicry between Synovial Hemangioma and Synovial Chondromatosis of the Shoulder. 61
28164062 2016
14
Synovial Hemangioma of Infrapatellar (Hoffa) Fat Pad: Magnetic Resonance Imaging and Ultrasound Features. 61
26922106 2016
15
[ARTHROSCOPIC RESECTION OF BENIGN TUMOR IN THE KNEE POSTERIOR SEPTUM]. 61
26455191 2015
16
Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review. 61
26193227 2015
17
Synovial Hemangioma of the Knee Joint: Magnetic Resonance Imaging Findings. 61
26491492 2015
18
Synovial hemangioma in the knee: MRI findings. 61
25973287 2015
19
Synovial hemangioma of Hoffa fat pad demonstrated by RBC SPECT/CT. 61
23917781 2014
20
Deformation of the patellofemoral joint caused by synovial hemangioma: a case report. 61
24626098 2014
21
[Synovial lipoma arborescens]. 61
25306627 2014
22
Synovial hemangioma and osteoarthritis of the knee: a case report. 61
25429592 2014
23
Synovial hemangioma of the hip joint in a pediatric patient. 61
24061493 2014
24
Synovial hemangioma of the knee with recurrent effusion and pain: a case report. 61
25149891 2014
25
Synovial hemangioma: a rare case of knee joint tumefaction in children. 61
24189010 2014
26
Benign synovial tumors and proliferative processes. 61
23673549 2013
27
[Prepatellar synovial hemangioma: a case report]. 61
23795441 2013
28
Synovial hemangioma accompanied by cruciate ligament injury in a dog. 61
23047431 2013
29
Synovial Angioma of the FDP Flexor Sheath: A Rare Cause of Carpal Tunnel Syndrome. 61
23569470 2013
30
Synovial hemangioma of the hip joint with pathological femoral neck fracture and extra-articular extension. 61
21773788 2013
31
Synovial hemangioma in an adult horse. 61
22362528 2012
32
Mimicry of lyme arthritis by synovial hemangioma. 61
20013264 2011
33
[A rare etiology of recurrent hemarthrosis in children: synovial hemangioma]. 61
21658919 2011
34
Recurrent hemarthrosis in a boy with synovial hemangioma: a case report. 61
21088622 2011
35
Destructive synovial hemangioma of the hip resembling pigmented villonodular synovitis. 61
20570091 2011
36
Synovial hemangioma of the knee joint in a 3-year-old girl. 61
20697297 2010
37
Synovial hemangioma of the knee joint in a 12-year-old boy: a case report. 61
20385009 2010
38
Synovial hemangioma of the ankle. 61
20353891 2010
39
Synovial hemangioma in a dog. 61
19538667 2009
40
Synovial hemangioma of the knee joint with cystic invasion of the femur: a case report and review of the literature. 61
18758797 2009
41
Arthroscopic excision of synovial hemangioma of the hip joint. 61
18696201 2008
42
Synovial hemangioma in the knee of a 10-month-old boy. 61
17701190 2008
43
Benign synovial disorders. 61
18460687 2008
44
Synovial hemangioma: a rare benign synovial lesion. 61
18603700 2008
45
Intraarticular synovial hemangioma of the knee: an unusual cause of chronic pain in a sportsman. 61
17993797 2007
46
Synovial knee affected in multiple hemangiomatosis. 61
17429665 2007
47
Synovial hemangioma of the knee. 61
17993072 2007
48
Synovial hemangiohamartomas of the knee joint. 61
16609865 2007
49
Pigmented villonodular synovitis causing painless chronic knee swelling in an adolescent. 61
17416886 2007
50
Synovial hemangioma in the stifle joint of a dog. 61
17317807 2007
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Variations for Synovial Angioma

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Expression for Synovial Angioma

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Search GEO for disease gene expression data for Synovial Angioma.
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Pathways for Synovial Angioma

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Pathways related to Synovial Angioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 65
Show member pathways
 12.75 F8 F7 F3 F2
2
Collagen chain trimerization 65
Show member pathways
 12.18 F8 F7 F3 F2
3
Folate Metabolism 1
Show member pathways
 11.83 F7 F2 CRP
4
Formation of Fibrin Clot (Clotting Cascade) 65
Show member pathways
 11.46 F8 F7 F3 F2
5
Complement and coagulation cascades 36 1
11.09 F8 F7 F3 F2
6
Warfarin Pathway, Pharmacodynamics 60
10.43 F7 F2
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GO Terms for Synovial Angioma

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Cellular components related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 F8 F7 F3 F2 CRP
2 collagen-containing extracellular matrix GO:0062023 9.5 F7 F3 F2
3 extracellular space GO:0005615 9.35 F8 F7 F3 F2 CRP
4 endoplasmic reticulum lumen GO:0005788 9.33 F8 F7 F2
5 serine-type peptidase complex GO:1905286 8.62 F7 F3

Biological processes related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.63 F8 F7 F2
2 protein processing GO:0016485 9.48 F7 F3
3 blood coagulation, intrinsic pathway GO:0007597 9.43 F8 F2
4 positive regulation of blood coagulation GO:0030194 9.4 F7 F2
5 positive regulation of positive chemotaxis GO:0050927 9.37 F7 F3
6 acute-phase response GO:0006953 9.33 F8 F2 CRP
7 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.32 F7 F3
8 blood coagulation, extrinsic pathway GO:0007598 9.26 F7 F3
9 blood coagulation GO:0007596 9.26 F8 F7 F3 F2
10 hemostasis GO:0007599 8.92 F8 F7 F3 F2

Molecular functions related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.26 KCNIP4 F7 F2 CRP
2 serine-type endopeptidase activity GO:0004252 8.8 F7 F3 F2
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Sources for Synovial Angioma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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