Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: SYN004
MIFTS: 29

Synovial Angioma

Categories: Cancer diseases, Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes
Sources

Aliases & Classifications for Synovial Angioma

About this section

MalaCards integrated aliases for Synovial Angioma:

Name: Synovial Angioma 12 15
Hemangioma of Synovium 12
Synovial Hemangioma 70

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:8274
NCIt 50 C6525
UMLS 70 C1336546
Sources

Summaries for Synovial Angioma

About this section
MalaCards based summary : Synovial Angioma, also known as hemangioma of synovium, is related to subclavian steal syndrome and factor xii deficiency, and has symptoms including pain An important gene associated with Synovial Angioma is KCNIP4 (Potassium Voltage-Gated Channel Interacting Protein 4), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include heart, small intestine and liver.

Sources

Related Diseases for Synovial Angioma

About this section

Diseases related to Synovial Angioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 subclavian steal syndrome 10.1 F3 CRP
2 factor xii deficiency 10.1 F7 F3
3 critical illness polyneuropathy 10.1 F3 CRP
4 aspiration pneumonitis 10.1 F3 CRP
5 coronary heart disease 1 10.1 F7 CRP
6 hantavirus hemorrhagic fever with renal syndrome 10.1 F3 CRP
7 endocarditis 10.1 F2 CRP
8 bronchopneumonia 10.0 F3 CRP
9 retinal vein occlusion 10.0 F3 F2
10 coronary thrombosis 10.0 F3 CRP
11 orbital osteomyelitis 10.0 F2 CRP
12 thrombasthenia 10.0 F3 F2
13 small intestine diverticulitis 10.0 F2 CRP
14 autoimmune disease of blood 10.0 F3 CRP
15 angina pectoris 10.0 F3 CRP
16 papillary adenofibroma 10.0 F3 F2
17 femoral neuropathy 10.0 F3 F2
18 scrub typhus 10.0 F3 CRP
19 hematocele of tunica vaginalis testis 10.0 F2 CRP
20 mycoplasma pneumoniae pneumonia 10.0 F3 CRP
21 giant hemangioma 10.0 F3 F2
22 hemopneumothorax 10.0 F3 F2
23 intermediate coronary syndrome 10.0 F3 CRP
24 cerebral falx meningioma 10.0 F3 F2
25 waterhouse-friderichsen syndrome 10.0 F3 F2
26 pulmonary embolism and infarction 10.0 F3 F2
27 acute pulmonary heart disease 10.0 F3 F2
28 subdural empyema 10.0 F2 CRP
29 internal hemorrhoid 10.0 F2 CRP
30 posterior cerebral artery infarction 10.0 F3 F2
31 hemorrhoid 10.0 F2 CRP
32 gastric hemangioma 10.0 F3 F2
33 acalculous cholecystitis 10.0 F2 CRP
34 hepatic infarction 10.0 F3 F2
35 carotid stenosis 10.0 F7 CRP
36 splenic abscess 10.0 F2 CRP
37 ascending cholangitis 10.0 F2 CRP
38 abducens nerve disease 10.0 F2 CRP
39 early congenital syphilis 10.0 F2 CRP
40 syphilis 10.0 F2 CRP
41 cerebral sinovenous thrombosis 10.0 F3 F2
42 cauda equina syndrome 10.0 F2 CRP
43 splenic tuberculosis 10.0 F2 CRP
44 paralytic ileus 10.0 F2 CRP
45 intracranial hypotension 10.0 F3 F2
46 ileus 10.0 F2 CRP
47 pyoderma 10.0 F3 CRP
48 acute cholangitis 10.0 F2 CRP
49 mastoiditis 10.0 F2 CRP
50 hepatic coma 10.0 F3 F2

Graphical network of the top 20 diseases related to Synovial Angioma:



Diseases related to Synovial Angioma
Sources

Symptoms & Phenotypes for Synovial Angioma

About this section

UMLS symptoms related to Synovial Angioma:


pain
Sources

Drugs & Therapeutics for Synovial Angioma

About this section

Search Clinical Trials , NIH Clinical Center for Synovial Angioma

Sources

Genetic Tests for Synovial Angioma

About this section
Sources

Anatomical Context for Synovial Angioma

About this section

MalaCards organs/tissues related to Synovial Angioma:

40
Heart, Small Intestine, Liver, Placenta, Testis, Pituitary
Sources

Publications for Synovial Angioma

About this section

Articles related to Synovial Angioma:

(show top 50) (show all 108)
# Title Authors PMID Year
1
Synovial Hemangioma of the Wrist With Cystic Invasion of Trapezoid and Capitate Bones. 61
31153656 2020
2
Synovial hemangioma of the knee joint in pediatrics: our case series and review of literature. 61
30980138 2019
3
Undiagnosed synovial hemangioma of the knee: a case report. 61
31311579 2019
4
[Synovial Haemangioma of the Knee - Diagnosis by Magnetic Resonance Imaging]. 61
31734979 2019
5
[Arthroscopic for the treatment of synovial hemangioma in knee joint: a case report]. 61
30884937 2019
6
[Synovial hemangioma of knee joint: a case report]. 61
30583658 2018
7
Synovial hemangiomas of wrist and ankle joint: A report of two rare cases. 61
30303163 2018
8
Synovial Hemangioma of the Temporomandibular Joint: Case Report. 61
30365579 2018
9
Articular abnormalities that may mimic arthritis. 61
30451404 2018
10
Synovial Hemangioma of the Knee Management and Excellent Outcome 2 Years after Arthroscopic Synovectomy in a 25-year-old Male with a 20-year History. 61
29051872 2017
11
It's not what it looks like: challenges in diagnosis of synovial lesions of the knee joint. 61
26915005 2016
12
Synovial Hemangioma Presenting as a Painful Locked Knee A Case Report. 61
27815956 2016
13
Case Report of Mimicry between Synovial Hemangioma and Synovial Chondromatosis of the Shoulder. 61
28164062 2016
14
Synovial Hemangioma of Infrapatellar (Hoffa) Fat Pad: Magnetic Resonance Imaging and Ultrasound Features. 61
26922106 2016
15
[ARTHROSCOPIC RESECTION OF BENIGN TUMOR IN THE KNEE POSTERIOR SEPTUM]. 61
26455191 2015
16
Arteriovenous synovial hemangioma of the popliteal fossa diagnosed in an adolescent with history of unilateral congenital clubfoot: case report and a single-institution retrospective review. 61
26193227 2015
17
Synovial hemangioma in the knee: MRI findings. 61
25973287 2015
18
Synovial Hemangioma of the Knee Joint: Magnetic Resonance Imaging Findings. 61
26491492 2015
19
Synovial hemangioma of Hoffa fat pad demonstrated by RBC SPECT/CT. 61
23917781 2014
20
Deformation of the patellofemoral joint caused by synovial hemangioma: a case report. 61
24626098 2014
21
[Synovial lipoma arborescens]. 61
25306627 2014
22
Synovial hemangioma and osteoarthritis of the knee: a case report. 61
25429592 2014
23
Synovial hemangioma of the hip joint in a pediatric patient. 61
24061493 2014
24
Synovial hemangioma: a rare case of knee joint tumefaction in children. 61
24189010 2014
25
Synovial hemangioma of the knee with recurrent effusion and pain: a case report. 61
25149891 2014
26
Benign synovial tumors and proliferative processes. 61
23673549 2013
27
[Prepatellar synovial hemangioma: a case report]. 61
23795441 2013
28
Synovial hemangioma accompanied by cruciate ligament injury in a dog. 61
23047431 2013
29
Synovial hemangioma of the hip joint with pathological femoral neck fracture and extra-articular extension. 61
21773788 2013
30
Synovial Angioma of the FDP Flexor Sheath: A Rare Cause of Carpal Tunnel Syndrome. 61
23569470 2013
31
Synovial hemangioma in an adult horse. 61
22362528 2012
32
Mimicry of lyme arthritis by synovial hemangioma. 61
20013264 2011
33
[A rare etiology of recurrent hemarthrosis in children: synovial hemangioma]. 61
21658919 2011
34
Recurrent hemarthrosis in a boy with synovial hemangioma: a case report. 61
21088622 2011
35
Destructive synovial hemangioma of the hip resembling pigmented villonodular synovitis. 61
20570091 2011
36
Synovial hemangioma of the knee joint in a 3-year-old girl. 61
20697297 2010
37
Synovial hemangioma of the knee joint in a 12-year-old boy: a case report. 61
20385009 2010
38
Synovial hemangioma of the ankle. 61
20353891 2010
39
Synovial hemangioma in a dog. 61
19538667 2009
40
Synovial hemangioma of the knee joint with cystic invasion of the femur: a case report and review of the literature. 61
18758797 2009
41
Arthroscopic excision of synovial hemangioma of the hip joint. 61
18696201 2008
42
Synovial hemangioma in the knee of a 10-month-old boy. 61
17701190 2008
43
Benign synovial disorders. 61
18460687 2008
44
Synovial hemangioma: a rare benign synovial lesion. 61
18603700 2008
45
Intraarticular synovial hemangioma of the knee: an unusual cause of chronic pain in a sportsman. 61
17993797 2007
46
Synovial knee affected in multiple hemangiomatosis. 61
17429665 2007
47
Synovial hemangioma of the knee. 61
17993072 2007
48
Synovial hemangiohamartomas of the knee joint. 61
16609865 2007
49
Pigmented villonodular synovitis causing painless chronic knee swelling in an adolescent. 61
17416886 2007
50
Synovial hemangioma in the stifle joint of a dog. 61
17317807 2007
Sources

Variations for Synovial Angioma

About this section
Sources

Expression for Synovial Angioma

About this section
Search GEO for disease gene expression data for Synovial Angioma.
Sources

Pathways for Synovial Angioma

About this section

Pathways related to Synovial Angioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 65
Show member pathways
 12.75 F8 F7 F3 F2
2
Collagen chain trimerization 65
Show member pathways
 12.19 F8 F7 F3 F2
3
Selenium Micronutrient Network 1
Show member pathways
 11.83 F7 F2 CRP
4
Formation of Fibrin Clot (Clotting Cascade) 65
Show member pathways
 11.46 F8 F7 F3 F2
5
Complement and coagulation cascades 36 1
11.09 F8 F7 F3 F2
6
Warfarin Pathway, Pharmacodynamics 60
10.43 F7 F2
Sources

GO Terms for Synovial Angioma

About this section

Cellular components related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 F8 F7 F3 F2 CRP
2 collagen-containing extracellular matrix GO:0062023 9.5 F7 F3 F2
3 extracellular space GO:0005615 9.35 F8 F7 F3 F2 CRP
4 endoplasmic reticulum lumen GO:0005788 9.33 F8 F7 F2
5 serine-type peptidase complex GO:1905286 8.62 F7 F3

Biological processes related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.63 F8 F7 F2
2 protein processing GO:0016485 9.48 F7 F3
3 blood coagulation, intrinsic pathway GO:0007597 9.43 F8 F2
4 positive regulation of blood coagulation GO:0030194 9.4 F7 F2
5 positive regulation of positive chemotaxis GO:0050927 9.37 F7 F3
6 acute-phase response GO:0006953 9.33 F8 F2 CRP
7 positive regulation of platelet-derived growth factor receptor signaling pathway GO:0010641 9.32 F7 F3
8 blood coagulation, extrinsic pathway GO:0007598 9.26 F7 F3
9 blood coagulation GO:0007596 9.26 F8 F7 F3 F2
10 hemostasis GO:0007599 8.92 F8 F7 F3 F2

Molecular functions related to Synovial Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 calcium ion binding GO:0005509 9.26 KCNIP4 F7 F2 CRP
2 serine-type endopeptidase activity GO:0004252 8.8 F7 F3 F2
Sources

Sources for Synovial Angioma

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....