MCID: SYN008
MIFTS: 22

Synovium Cancer

Categories: Cancer diseases

Aliases & Classifications for Synovium Cancer

MalaCards integrated aliases for Synovium Cancer:

Name: Synovium Cancer 12 15
Malignant Tumor of Synovium 12
Synovial Neoplasm 71

Classifications:



External Ids:

Disease Ontology 12 DOID:2706
NCIt 49 C6531
UMLS 71 C0476203 C1334624

Summaries for Synovium Cancer

MalaCards based summary : Synovium Cancer, also known as malignant tumor of synovium, is related to sarcoma, synovial and epithelioid cell synovial sarcoma. An important gene associated with Synovium Cancer is CFAP47 (Cilia And Flagella Associated Protein 47), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Mesenchymal Stem Cells and Lineage-specific Markers. Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Synovium Cancer

Diseases related to Synovium Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)
# Related Disease Score Top Affiliating Genes
1 sarcoma, synovial 29.9 TLE1 SSX4B SSX4 SSX2 SSX1 SS18
2 epithelioid cell synovial sarcoma 10.7 SSX2 SSX1
3 tibial adamantinoma 10.7 TLE1 SSX1
4 adamantinoma of long bones 10.7 TLE1 SSX1
5 meninges sarcoma 10.7 SSX2 SS18
6 cellular neurofibroma 10.6 TLE1 SMARCB1
7 spindle cell liposarcoma 10.6 TLE1 CD34
8 nasal cavity benign neoplasm 10.6 EWSR1 CD34
9 central nervous system angiosarcoma 10.6 SMARCB1 CD34
10 bone angioendothelial sarcoma 10.6 SSX4B SSX4 SS18
11 intracranial primitive neuroectodermal tumor 10.6 EWSR1 CD99
12 vulvar sarcoma 10.6 SMARCB1 EWSR1
13 pulmonary vein leiomyosarcoma 10.6 CD99 CD34
14 extraskeletal chondroma 10.6 SERPINA3 EWSR1
15 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.6 EWSR1 CD99
16 spermatic cord cancer 10.6 SSX2 SSX1 CD34
17 spinal cord sarcoma 10.6 KIT CD34
18 kidney hemangiopericytoma 10.6 SSX2 SS18 CD34
19 gallbladder leiomyoma 10.6 KIT CD34
20 thymic epithelial tumor 10.6 KIT CD99
21 liver fibroma 10.6 SSX2 KIT
22 cellular schwannoma 10.6 SSX1 SS18 CD34
23 small intestine leiomyosarcoma 10.6 KIT CD34
24 small cell sarcoma 10.6 EWSR1 CCNB3
25 uterine sarcoma 10.6 SMARCB1 KIT
26 proliferative fasciitis 10.6 SMARCB1 SERPINA3
27 peripheral nerve schwannoma 10.6 SMARCB1 SERPINA3
28 myocardium cancer 10.6 MYOG CD99
29 deep leiomyoma 10.6 KIT CD34
30 ewing sarcoma of bone 10.6 EWSR1 CD99
31 extraskeletal mesenchymal chondrosarcoma 10.6 SSX1 EWSR1 CD99
32 mucocele of appendix 10.6 KIT CD34
33 gastric liposarcoma 10.6 KIT CD34
34 cellular congenital mesoblastic nephroma 10.6 TLE1 SSX2 CCNB3
35 gallbladder leiomyosarcoma 10.6 KIT CD34
36 undifferentiated embryonal sarcoma of the liver 10.6 SERPINA3 MYOG
37 breast rhabdomyosarcoma 10.6 PAX3 MYOG
38 meninges hemangiopericytoma 10.6 CD99 CD34
39 orbit rhabdomyosarcoma 10.6 PAX3 MYOG
40 epidural spinal canal neoplasm 10.6 CD99 CD34
41 jejunal neoplasm 10.6 KIT CD34
42 plexiform schwannoma 10.6 KIT CD34
43 bladder sarcoma 10.5 SERPINA3 MYOG
44 malignant glandular tumor of peripheral nerve sheath 10.5 TLE1 SSX2 MYOG
45 liposarcoma of bone 10.5 MYOG CD34
46 cutaneous solitary mastocytoma 10.5 SERPINA3 KIT
47 liver leiomyoma 10.5 KIT CD34
48 sarcomatoid squamous cell skin carcinoma 10.5 SERPINA3 CD34
49 retroperitoneal hemangiopericytoma 10.5 KIT CD34
50 pulmonary vein stenosis 10.5 KIT CD99

Graphical network of the top 20 diseases related to Synovium Cancer:



Diseases related to Synovium Cancer

Symptoms & Phenotypes for Synovium Cancer

GenomeRNAi Phenotypes related to Synovium Cancer according to GeneCards Suite gene sharing:

26 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-110 9.55 TLE1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.55 TLE1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-126 9.55 EWSR1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-137 9.55 EWSR1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-140 9.55 EWSR1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-146 9.55 EWSR1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-183 9.55 TLE1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.55 EWSR1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-23 9.55 SSX1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-52 9.55 EWSR1 SSX1
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.55 EWSR1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-76 9.55 SSX2
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.55 EWSR1
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-81 9.55 EWSR1 SSX2
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.55 EWSR1

Drugs & Therapeutics for Synovium Cancer

Search Clinical Trials , NIH Clinical Center for Synovium Cancer

Genetic Tests for Synovium Cancer

Anatomical Context for Synovium Cancer

Publications for Synovium Cancer

Articles related to Synovium Cancer:

# Title Authors PMID Year
1
Subcutaneous pigmented villonodular synovitis caused by portal contamination during knee arthroscopy and open synovectomy. 61
15067291 2004
2
Synovial chondromatosis: a case study and brief review. 61
9021034 1997
3
[Diagnosis and treatment of lateral crypta synovial crush syndrome of knee]. 61
8731887 1995
4
Primary synovial chondromatosis of the ankle. A case report. 61
956234 1976

Variations for Synovium Cancer

Expression for Synovium Cancer

Search GEO for disease gene expression data for Synovium Cancer.

Pathways for Synovium Cancer

Pathways related to Synovium Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.3 SSX2 SSX1 SS18 PAX3 EWSR1
2 11.23 PAX3 MYOG KIT CD34

GO Terms for Synovium Cancer

Cellular components related to Synovium Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 npBAF complex GO:0071564 8.62 SS18 SMARCB1

Biological processes related to Synovium Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.56 TLE1 SSX4B SSX4 SSX2 SSX1 PAX3
2 tRNA threonylcarbamoyladenosine metabolic process GO:0070525 8.62 CTAG1B CTAG1A

Sources for Synovium Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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