SPD3
MCID: SYN040
MIFTS: 16

Synpolydactyly 3 (SPD3)

Categories: Bone diseases, Fetal diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Synpolydactyly 3

MalaCards integrated aliases for Synpolydactyly 3:

Name: Synpolydactyly 3 57 13 70
Spd3 57 58
Synpolydactyly, Malik Type 58
Synpolydactyly Type 3 58
Sd2, Malik Type 58
Spd, Malik Type 58
Sd2c 58

Classifications:

Orphanet: 58  
Rare bone diseases
Developmental anomalies during embryogenesis


External Ids:

OMIM® 57 610234
ICD10 via Orphanet 33 Q70.0 Q70.2
UMLS via Orphanet 71 C1853255
Orphanet 58 ORPHA295199
MedGen 41 C1853255
UMLS 70 C1853255

Summaries for Synpolydactyly 3

MalaCards based summary : Synpolydactyly 3, also known as spd3, is related to synpolydactyly and synpolydactyly 2. An important gene associated with Synpolydactyly 3 is SPD3 (Synpolydactyly 3).

More information from OMIM: 610234

Related Diseases for Synpolydactyly 3

Diseases in the Synpolydactyly family:

Synpolydactyly 1 Synpolydactyly 2
Synpolydactyly 3

Diseases related to Synpolydactyly 3 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 synpolydactyly 11.4
2 synpolydactyly 2 11.3
3 chromosome 2q35 duplication syndrome 9.9
4 synpolydactyly 1 9.9

Symptoms & Phenotypes for Synpolydactyly 3

Clinical features from OMIM®:

610234 (Updated 05-Apr-2021)

Drugs & Therapeutics for Synpolydactyly 3

Search Clinical Trials , NIH Clinical Center for Synpolydactyly 3

Genetic Tests for Synpolydactyly 3

Anatomical Context for Synpolydactyly 3

Publications for Synpolydactyly 3

Articles related to Synpolydactyly 3:

(show all 14)
# Title Authors PMID Year
1
Genetic heterogeneity of synpolydactyly: a novel locus SPD3 maps to chromosome 14q11.2-q12. 57 61
16712704 2006
2
Polyamine blockade and binding energetics in the MthK potassium channel. 61
32342093 2020
3
Detection of Streptococcus pyogenes Virulence Factors. 61
32430809 2020
4
[Investigation of Streptococcus pyogenes virulence factors and typing by multiple locus variable number tandem repeat fingerprinting (MLVF) method]. 61
30156510 2018
5
Unique genomic arrangements in an invasive serotype M23 strain of Streptococcus pyogenes identify genes that induce hypervirulence. 61
25225265 2014
6
Detection of Streptococcus pyogenes virulence factors by multiplex PCR. 61
23076284 2012
7
A new rapid and cost-effective method for detection of phages, ICEs and virulence factors encoded by Streptococcus pyogenes. 61
22184925 2011
8
CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes. 61
19451242 2009
9
Synpolydactyly and HOXD13 polyalanine repeat: addition of 2 alanine residues is without clinical consequences. 61
18072967 2007
10
A molecular dynamics simulation study of polyamine- and sodium-DNA. Interplay between polyamine binding and DNA structure. 61
15146298 2004
11
A molecular dynamics simulation study of oriented DNA with polyamine and sodium counterions: diffusion and averaged binding of water and cations. 61
14530445 2003
12
Polyamines and pectins. II. Modulation of pectic-signal transduction. 61
10333588 1999
13
Initiation of sporulation in Saccharomyces cerevisiae. Mutations preventing initiation. 61
6374029 1984
14
Initiation of sporulation in Saccharomyces cerevisiae. Mutations causing derepressed sporulation and G1 arrest in the cell division cycle. 61
6374028 1984

Variations for Synpolydactyly 3

Expression for Synpolydactyly 3

Search GEO for disease gene expression data for Synpolydactyly 3.

Pathways for Synpolydactyly 3

GO Terms for Synpolydactyly 3

Sources for Synpolydactyly 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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