MCID: SYP001
MIFTS: 23

Syphilitic Meningitis

Categories: Neuronal diseases

Aliases & Classifications for Syphilitic Meningitis

MalaCards integrated aliases for Syphilitic Meningitis:

Name: Syphilitic Meningitis 12 15
Syphilitic Aseptic Meningitis 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10073
ICD9CM 36 094.2
MeSH 45 C536775
SNOMED-CT 69 14968007
UMLS 74 C0153166

Summaries for Syphilitic Meningitis

Disease Ontology : 12 A bacterial meningitis that is characterized by inflammation of the tissues covering the brain and spinal cord.

MalaCards based summary : Syphilitic Meningitis, also known as syphilitic aseptic meningitis, is related to syphilitic aseptic meningitis and meningitis. An important gene associated with Syphilitic Meningitis is EXTL3 (Exostosin Like Glycosyltransferase 3). Affiliated tissues include brain, spinal cord and t cells.

Related Diseases for Syphilitic Meningitis

Diseases related to Syphilitic Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 syphilitic aseptic meningitis 11.7
2 meningitis 10.6
3 systemic lupus erythematosus 9.9
4 intracranial hypertension, idiopathic 9.9
5 papilledema 9.9
6 secondary syphilis 9.9
7 syphilis 9.9
8 paraplegia 9.9
9 lupus erythematosus 9.9
10 hypopituitarism 9.9
11 tuberculous meningitis 9.9
12 pre-eclampsia 9.6 ENPEP SERPINC1
13 human immunodeficiency virus infectious disease 9.6 ENPEP ITIH4

Graphical network of the top 20 diseases related to Syphilitic Meningitis:



Diseases related to Syphilitic Meningitis

Symptoms & Phenotypes for Syphilitic Meningitis

Drugs & Therapeutics for Syphilitic Meningitis

Search Clinical Trials , NIH Clinical Center for Syphilitic Meningitis

Cochrane evidence based reviews: syphilitic aseptic meningitis

Genetic Tests for Syphilitic Meningitis

Anatomical Context for Syphilitic Meningitis

MalaCards organs/tissues related to Syphilitic Meningitis:

42
Brain, Spinal Cord, T Cells, B Cells

Publications for Syphilitic Meningitis

Articles related to Syphilitic Meningitis:

(show all 25)
# Title Authors Year
1
Acute syphilitic meningitis in an HIV-infected patient. ( 30101068 )
2018
2
Comparative study of CD4 and CD45RO T cells and CD20 B cells in cerebrospinal fluid of syphilitic meningitis and tuberculous meningitis patients. ( 27467195 )
2016
3
Acute hypophysitis and hypopituitarism in early syphilitic meningitis in a HIV-infected patient: a case report. ( 24134407 )
2013
4
Tuberculous and syphilitic meningitis in a patient infected with the human immunodeficiency virus. ( 17409609 )
2007
5
Syphilitic meningitis in HIV-patients with meningeal syndrome: report of two cases and review. ( 11779455 )
2001
6
Concomitant human immunodeficiency virus infection and syphilitic meningitis. ( 9064008 )
1996
7
Acute syphilitic meningitis in a patient with systemic lupus erythematosus. ( 8336315 )
1993
8
Acute syphilitic meningitis in a man with seropositivity for human immunodeficiency virus infection and normal numbers of CD4 T lymphocytes. ( 1350899 )
1992
9
Syphilitic meningitis causing paraparesis in an HIV-negative woman. ( 1865231 )
1991
10
Chronic syphilitic meningitis resulting in superior orbital fissure syndrome and posterior fossa gumma. A report of two cases followed for 20 years. ( 2971679 )
1988
11
Syphilitic meningitis masquerading as pseudotumor cerebri. ( 3579655 )
1987
12
Acute syphilitic meningitis. Its occurrence after clinical and serologic cure of secondary syphilis with penicillin G. ( 3947251 )
1986
13
Acute syphilitic meningitis: a case report. ( 312449 )
1979
14
Syphilitic meningitis with papilledema. ( 887964 )
1977
15
Report of a case of probable syphilitic meningitis. ( 18891508 )
1948
16
Acute syphilitic meningitis; a report of 80 cases. ( 18895277 )
1948
17
Acute syphilitic meningitis treated with penicillin; a progress report. ( 20984456 )
1946
18
Syphilitic meningitis with negative blood and spinal fluid serology, report of a rare syndrome. ( 20994580 )
1946
19
Unilateral internal ophthalmoplegia; sole clinical sign in patient with syphilitic meningitis. ( 21012276 )
1945
20
Acute Syphilitic Meningitis Occurring During Treatment. ( 19992119 )
1939
21
Acute Syphilitic Meningitis with Papilloedema. ( 19991058 )
1937
22
Acute Syphilitic Meningitis with Papillœdema. ( 20915455 )
1937
23
ACUTE SYPHILITIC MENINGITIS. ( 20768750 )
1917
24
Compression Paraplegia: Syphilitic Meningitis. ( 19974507 )
1910
25
Chronic Syphilitic Meningitis with Compression of the Cord. ( 19974515 )
1910

Variations for Syphilitic Meningitis

Expression for Syphilitic Meningitis

Search GEO for disease gene expression data for Syphilitic Meningitis.

Pathways for Syphilitic Meningitis

GO Terms for Syphilitic Meningitis

Cellular components related to Syphilitic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 8.96 ITIH4 SERPINC1
2 blood microparticle GO:0072562 8.62 ITIH4 SERPINC1

Biological processes related to Syphilitic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of endopeptidase activity GO:0010951 8.96 ITIH4 SERPINC1
2 negative regulation of peptidase activity GO:0010466 8.62 ITIH4 SERPINC1

Molecular functions related to Syphilitic Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 8.96 ITIH4 SERPINC1
2 serine-type endopeptidase inhibitor activity GO:0004867 8.62 ITIH4 SERPINC1

Sources for Syphilitic Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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