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SLEB2
MCID: SYS038
MIFTS: 23
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Systemic Lupus Erythematosus 2 (SLEB2)
Categories:
Bone diseases, Genetic diseases, Immune diseases, Nephrological diseases, Rare diseases, Skin diseases
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MalaCards integrated aliases for Systemic Lupus Erythematosus 2:
Classifications:
MalaCards categories:
Global: Genetic diseases Rare diseases Anatomical: Bone diseases Immune diseases Nephrological diseases Skin diseases |
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UniProtKB/Swiss-Prot
:
76
Systemic lupus erythematosus 2: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
MalaCards based summary : Systemic Lupus Erythematosus 2, also known as systemic lupus erythematosus, susceptibility to, 2, is related to systemic lupus erythematosus and lupus erythematosus. An important gene associated with Systemic Lupus Erythematosus 2 is PDCD1 (Programmed Cell Death 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include skin, kidney and bone.
Description from OMIM:
605218
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Diseases in the Lupus Erythematosus family:Diseases related to Systemic Lupus Erythematosus 2 via text searches within MalaCards or GeneCards Suite gene sharing:
Graphical network of the top 20 diseases related to Systemic Lupus Erythematosus 2:
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MalaCards organs/tissues related to Systemic Lupus Erythematosus 2:42
Skin,
Kidney,
Bone,
Bone Marrow,
Testes
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Articles related to Systemic Lupus Erythematosus 2:
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Genes related to Systemic Lupus Erythematosus 2 (1 elite genes): - Elite gene
- Cancer Census gene in COSMIC
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Search
GEO
for disease gene expression data for Systemic Lupus Erythematosus 2.
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