SLEB3
MCID: SYS046
MIFTS: 21

Systemic Lupus Erythematosus 3 (SLEB3)

Categories: Blood diseases, Bone diseases, Genetic diseases, Immune diseases, Nephrological diseases, Rare diseases, Skin diseases

Aliases & Classifications for Systemic Lupus Erythematosus 3

MalaCards integrated aliases for Systemic Lupus Erythematosus 3:

Name: Systemic Lupus Erythematosus 3 56
Systemic Lupus Erythematosus, Susceptibility to, 3 56 13
Sleb3 56

Classifications:



External Ids:

OMIM 56 605480
MedGen 41 C1854235

Summaries for Systemic Lupus Erythematosus 3

MalaCards based summary : Systemic Lupus Erythematosus 3, also known as systemic lupus erythematosus, susceptibility to, 3, is related to systemic lupus erythematosus and lupus erythematosus. An important gene associated with Systemic Lupus Erythematosus 3 is SLEB3 (Systemic Lupus Erythematosus Susceptibility 3). The drugs Estrogens and Hormone Antagonists have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and testes.

More information from OMIM: 605480

Related Diseases for Systemic Lupus Erythematosus 3

Symptoms & Phenotypes for Systemic Lupus Erythematosus 3

Clinical features from OMIM:

605480

Drugs & Therapeutics for Systemic Lupus Erythematosus 3

Drugs for Systemic Lupus Erythematosus 3 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Estrogens Phase 4
2 Hormone Antagonists Phase 4
3 Hormones Phase 4
4 Estrogens, Conjugated (USP) Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect Of Hormone Replacement Therapy On Disease Activity, Menopausal Symptoms And Bone Mineral Density In Peri/Postmenopausal Women With Systemic Lupus Erythematosus.Randomized Clinical Trial Completed NCT00392093 Phase 4 Conjugated equine estrogens 0.625 mg/d + MPA 5 mg/d/10d

Search NIH Clinical Center for Systemic Lupus Erythematosus 3

Genetic Tests for Systemic Lupus Erythematosus 3

Anatomical Context for Systemic Lupus Erythematosus 3

MalaCards organs/tissues related to Systemic Lupus Erythematosus 3:

40
Bone, Liver, Testes, Neutrophil, Kidney, B Cells, Endothelial

Publications for Systemic Lupus Erythematosus 3

Articles related to Systemic Lupus Erythematosus 3:

(show all 44)
# Title Authors PMID Year
1
Localization and replication of the systemic lupus erythematosus linkage signal at 4p16: interaction with 2p11, 12q24 and 19q13 in European Americans. 56
16983533 2007
2
SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations. 56
12136236 2002
3
Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. 56
11078476 2000
4
Frontal fibrosing alopecia demographics: a survey of 29 patients. 61
30893399 2019
5
Bamboo Nodes of Vocal Folds: A Description of 10 Cases and Review of the Literature. 61
29847817 2018
6
[The function and the significance of full-automated tests for detecting antiphospholipid antibodies]. 61
26213194 2015
7
Anticyclic citrullinated peptide antibodies in rheumatoid and nonrheumatoid rheumatic disorders: experience with 1162 patients. 61
25274898 2014
8
A study on oral mucosal lesions in 3500 patients with dermatological diseases in South India. 61
25184094 2014
9
The implication of vitamin D and autoimmunity: a comprehensive review. 61
23359064 2013
10
A Delphi Consensus Approach to Challenging Case Scenarios in Moderate-to-Severe Psoriasis: Part 1. 61
23205324 2012
11
Pleuropulmonary pathology in patients with rheumatic disease. 61
23020730 2012
12
Atypical lymphoplasmacytic and immunoblastic proliferation of autoimmune disease : clinicopathologic and immunohistochemical study of 9 cases. 61
21123969 2010
13
Kidney transplantation during autoimmune diseases. 61
19765434 2009
14
Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option. 61
19758225 2009
15
Neutrophilic urticarial dermatosis: a variant of neutrophilic urticaria strongly associated with systemic disease. Report of 9 new cases and review of the literature. 61
19352297 2009
16
Pregnancy outcome in lupus nephropathy. 61
15052490 2005
17
Low frequency of anti-SLA/LP autoantibody in Japanese adult patients with autoimmune liver diseases: analysis with recombinant antigen assay. 61
12892738 2003
18
Changes in lymphocytic cluster distribution during extracorporeal immunoadsorption. 61
11879242 2002
19
Autoimmune lymphoproliferative syndrome, a disorder of apoptosis. 61
10590910 1999
20
Recurrent and de novo glomerular disease after renal transplantation: a report from Renal Allograft Disease Registry (RADR). 61
10507481 1999
21
Clinical presentation and disease associations of gout: a hospital-based study of 100 patients in Singapore. 61
9588267 1998
22
Increased serum levels of soluble CD44-isoform v5 in rheumatic diseases are restricted to seropositive rheumatoid arthritis. 61
9150806 1997
23
Clinical significance of complements in ascitic diseases: elevated complement levels disapproving the liver disease origin. 61
8931344 1996
24
Modifications of biochemical markers of bone and collagen turnover during corticosteroid therapy. 61
8778165 1996
25
Determinants of survival in pediatric continuous hemofiltration. 61
8589315 1995
26
Use of antineutrophil cytoplasmic autoantibodies in diagnosing vasculitis in a Chinese patient population. 61
7915885 1994
27
T and B cell immune response to a 55-kDa endothelial cell-derived antigen in severe asthma. 61
8458370 1993
28
Use of anti-thymocyte globulin in the management of refractory systemic autoimmune diseases. 61
8266027 1993
29
[Internal ear dysfunction in systemic autoimmune diseases: study of sensorineural hearing loss probably originated by autoimmune disorders (preliminary study)]. 61
2268458 1990
30
Depressed plasma fibrinolytic activity in a group of patients with connective tissue diseases. 61
2512638 1989
31
[Lip ulceration disclosing systemic lupus erythematosus: 3 cases]. 61
2619176 1989
32
Venous thrombosis associated with lupus anticoagulant and anticardiolipin antibodies. 61
3144118 1988
33
Occurrence of Kawasaki disease and systemic lupus erythematosus in a single patient. 61
3379628 1988
34
Studies of macrophage function in murine systemic lupus erythematosus. 3. The nature, anatomical location, and reversibility of the phagocytic defect. 61
3455711 1986
35
Antikeratin antibodies in serum and synovial fluid show specificity for rheumatoid arthritis in a study of connective tissue diseases. 61
2411231 1985
36
Urinary bladder tumors following cyclophosphamide therapy: a report of two cases with a review of the literature. 61
3982369 1985
37
[Effect of the method of extracorporeal heparin precipitation of plasma proteins (selective plasmapheresis) on the level of immune complexes in the blood]. 61
2931844 1985
38
Development and application of an enzyme-linked immunosorbent assay for the quantitation of alternative complement pathway activation in human serum. 61
6418767 1984
39
[Nursing of patients with systemic lupus erythematosus. 3]. 61
6901940 1980
40
Early pleural decortication for thoracic empyema in immunosuppressed patients. 61
904351 1977
41
Immunoglobulin E in renal disease. 61
55986 1976
42
Systemic lupus erythematosus and spontaneously arising anticoagulants. 61
1188558 1975
43
Laboratory tests for diagnosis of autoimmune diseases. 61
1105671 1975
44
Family studies in systemic lupus erythematosus. 3. Presence of LE factor in relatives and spouses. 61
4124130 1972

Variations for Systemic Lupus Erythematosus 3

Expression for Systemic Lupus Erythematosus 3

Search GEO for disease gene expression data for Systemic Lupus Erythematosus 3.

Pathways for Systemic Lupus Erythematosus 3

GO Terms for Systemic Lupus Erythematosus 3

Sources for Systemic Lupus Erythematosus 3

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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