MCID: TCL001
MIFTS: 41

T-Cell Adult Acute Lymphocytic Leukemia

Categories: Blood diseases, Cancer diseases, Immune diseases

Aliases & Classifications for T-Cell Adult Acute Lymphocytic Leukemia

MalaCards integrated aliases for T-Cell Adult Acute Lymphocytic Leukemia:

Name: T-Cell Adult Acute Lymphocytic Leukemia 12 15
T-Cell Adult Acute Lymphoblastic Leukemia 74
Adult Precursor T Lymphoblastic Leukemia 12
Acute Adult T-Cell Leukemia-Lymphoma 12
Atll 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5602
NCIt 51 C9142
UMLS 74 C0279592

Summaries for T-Cell Adult Acute Lymphocytic Leukemia

MalaCards based summary : T-Cell Adult Acute Lymphocytic Leukemia, also known as t-cell adult acute lymphoblastic leukemia, is related to adult t-cell leukemia and peripheral t-cell lymphoma. An important gene associated with T-Cell Adult Acute Lymphocytic Leukemia is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Prednisone and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and kidney, and related phenotypes are hematopoietic system and growth/size/body region

Related Diseases for T-Cell Adult Acute Lymphocytic Leukemia

Diseases in the B-Cell Adult Acute Lymphocytic Leukemia family:

T-Cell Adult Acute Lymphocytic Leukemia

Diseases related to T-Cell Adult Acute Lymphocytic Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 adult t-cell leukemia 30.2 BCL11B CADM1 FOXP3 IL2 PTHLH
2 peripheral t-cell lymphoma 30.0 CD5 IL2 TIA1
3 leukemia 10.6
4 lymphoma 10.6
5 t-cell leukemia 10.6
6 adult acute lymphocytic leukemia 10.4 CD2 INPP5D
7 lethal midline granuloma 10.3 CD2 TIA1
8 clostridium difficile colitis 10.3 CCR6 TOX
9 natural killer cell leukemia 10.3 CD2 TIA1
10 thymic dysplasia 10.3 CD2 FOXP3
11 immune defect due to absence of thymus 10.2 CD2 IL2
12 composite lymphoma 10.2 CD5 TIA1
13 adult lymphoma 10.2 CD2 CD5
14 mast cell neoplasm 10.2 CD2 IL2
15 autoimmune lymphoproliferative syndrome, type v 10.2 CD5 TIA1
16 necrotizing sialometaplasia 10.2 CD5 TIA1
17 t cell deficiency 10.2 CD2 IL2
18 limited scleroderma 10.2 CCR6 IL2
19 human t-cell leukemia virus type 1 10.1
20 lymphatic system cancer 10.1 CD2 CD5 TIA1
21 sezary's disease 10.1 CD2 IL2 TOX
22 murray valley encephalitis 10.1 ERVW-1 IL2
23 pulmonary hemosiderosis 10.1
24 hemosiderosis 10.1
25 leukocyte disease 10.1 CD2 CD5 IL2
26 ileum cancer 10.0 CD5 TIA1
27 thymoma 10.0 CD2 CD5 IL2
28 thymus gland disease 10.0 CD5 IL2
29 b-cell expansion with nfkb and t-cell anergy 10.0 CD5 IL2 TIA1
30 autoimmune disease of endocrine system 10.0 FOXP3 IL2
31 myelopathy, htlv-1-associated 10.0
32 lymphoma, hodgkin, classic 10.0
33 mycosis fungoides 10.0
34 lymphoblastic lymphoma 10.0
35 strongyloidiasis 10.0
36 cystoisosporiasis 10.0
37 tropical spastic paraparesis 10.0
38 spastic paraparesis 10.0
39 hepatosplenic t-cell lymphoma 10.0
40 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 10.0 ERVW-1 FOXP3 IL2
41 lepromatous leprosy 9.9 CD2 IL2
42 hematologic cancer 9.9 CD2 CD5 IL2 PTHLH
43 spinal cord disease 9.7 ERVW-1 HBZ

Graphical network of the top 20 diseases related to T-Cell Adult Acute Lymphocytic Leukemia:



Diseases related to T-Cell Adult Acute Lymphocytic Leukemia

Symptoms & Phenotypes for T-Cell Adult Acute Lymphocytic Leukemia

MGI Mouse Phenotypes related to T-Cell Adult Acute Lymphocytic Leukemia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 BCL11B CADM1 CCR6 CD5 FOXP3 HBZ
2 growth/size/body region MP:0005378 9.97 ATN1 BCL11B CADM1 FOXP3 HBZ IL2
3 endocrine/exocrine gland MP:0005379 9.91 ATN1 BCL11B CADM1 FOXP3 IL2 INPP5D
4 immune system MP:0005387 9.85 BCL11B CADM1 CCR6 CD5 FOXP3 IL2
5 integument MP:0010771 9.43 ATN1 BCL11B CD5 FOXP3 INPP5D PTHLH
6 normal MP:0002873 9.17 ATN1 CADM1 CCR6 CD2 CD5 FOXP3

Drugs & Therapeutics for T-Cell Adult Acute Lymphocytic Leukemia

Drugs for T-Cell Adult Acute Lymphocytic Leukemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 387)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
2
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 3778-73-2 3690
3
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 33419-42-0 36462
4
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 2068-78-2, 57-22-7 5978
5
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 50-02-2 5743
6
Epirubicin Approved Phase 4,Phase 2 56420-45-2 41867
7
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 50-18-0, 6055-19-2 2907
8
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 1177-87-3
9
Cisplatin Approved Phase 4,Phase 2,Phase 1 15663-27-1 2767 441203 84093
10
Gemcitabine Approved Phase 4,Phase 2,Phase 1 95058-81-4 60750
11
Zidovudine Approved Phase 4,Phase 2 30516-87-1 35370
12
Peginterferon alfa-2b Approved Phase 4,Phase 2 215647-85-1, 99210-65-8
13
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
14 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
15 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
16 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
19 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
20 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
21 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
22 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
23 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Etoposide phosphate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
26 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
27 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
28 BB 1101 Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
29 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
30 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31
Isophosphamide mustard Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 0
32 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
33 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable
35 Anti-HIV Agents Phase 4,Phase 2,Phase 1,Not Applicable
36 Antimetabolites Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Anti-Retroviral Agents Phase 4,Phase 2,Phase 1,Not Applicable
38 Neurotransmitter Agents Phase 4,Phase 3,Phase 1,Not Applicable
39 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
40 Central Nervous System Depressants Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
41 GABA Agents Phase 4,Phase 1
42 Anticonvulsants Phase 4,Phase 1
43 Psychotropic Drugs Phase 4,Phase 3,Not Applicable
44 Reverse Transcriptase Inhibitors Phase 4,Phase 2,Not Applicable
45 Interferon alpha-2 Phase 4,Phase 2,Phase 1
46 Tranquilizing Agents Phase 4,Phase 3,Not Applicable
47 interferons Phase 4,Phase 2,Phase 1
48 Interferon-alpha Phase 4,Phase 2,Phase 1
49 Antimanic Agents Phase 4
50
Ketamine Approved, Vet_approved Phase 3 6740-88-1 3821

Interventional clinical trials:

(show top 50) (show all 320)
# Name Status NCT ID Phase Drugs
1 CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL Unknown status NCT02533700 Phase 4 CEOP/IVE/GDP chemotherapy regimen;CEOP chemotherapy regimen for 6 cycles
2 Pilot Study of Combination Therapy With CHOP-Zenapax (CHOP-daclizumab) Completed NCT01418430 Phase 4 CHOP-daclizumab
3 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Completed NCT03226119 Phase 4
4 Zidovudine, Interferon Alfa-2b, PEG-Interferon Alfa-2b in Patients With HTLV-I Associated Adult T-Cell Leukemia/Lymphoma Terminated NCT00854581 Phase 4 Valproic Acid;Zidovudine
5 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3 ketamine hydrochloride
6 Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia Unknown status NCT00445497 Phase 3 amoxicillin-clavulanate potassium;ciprofloxacin
7 Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia Unknown status NCT00020865 Phase 3 cefepime hydrochloride;levofloxacin
8 Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma Unknown status NCT00052936 Phase 3 CHOP regimen;cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
9 A Study for Aggressive Adult T-cell Leukemia-lymphoma (ATLL) Completed NCT00145002 Phase 3 VCAP-AMP-VECP with G-CSF and intrathecal prophylaxis;biweekly-CHOP with G-CSF and intrathecal prophylaxis
10 Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma Who Have Undergone Stem Cell Transplantation Completed NCT00031668 Phase 3
11 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
12 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3 American ginseng
13 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
14 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3 sodium ferric gluconate complex in sucrose
15 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
16 St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer Completed NCT00005805 Phase 3
17 Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count Completed NCT00003805 Phase 3 piperacillin sodium;piperacillin-tazobactam;tazobactam sodium;vancomycin
18 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3 Fragmin
19 Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer Completed NCT00070382 Phase 3 darbepoetin alfa;epoetin alfa
20 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
21 Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma Completed NCT00005590 Phase 3 levofloxacin
22 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
23 Treatment for Chronic Pain in Patients With Advanced Cancer Completed NCT00003687 Phase 3 dextromethorphan hydrobromide;morphine sulfate
24 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
25 Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma Completed NCT00002766 Phase 3 carmustine;cyclophosphamide;cytarabine;daunorubicin hydrochloride;doxorubicin hydrochloride;etoposide;mercaptopurine;methotrexate;mitoxantrone hydrochloride;pegaspargase;prednisone;vincristine sulfate
26 Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Recruiting NCT01085617 Phase 3 cyclophosphamide;cytarabine;daunorubicin hydrochloride;etoposide;fludarabine phosphate;imatinib mesylate;melphalan;mercaptopurine;methotrexate;nelarabine;pegaspargase;vincristine sulfate
27 Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer Active, not recruiting NCT00003816 Phase 2, Phase 3 busulfan;carboplatin;cyclophosphamide;etoposide;fludarabine phosphate;melphalan;thiotepa
28 Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma Suspended NCT02112916 Phase 3 Bortezomib;Cyclophosphamide;Cytarabine;Daunorubicin Hydrochloride;Dexamethasone;Doxorubicin Hydrochloride;Etoposide;Hydrocortisone Sodium Succinate;Ifosfamide;Leucovorin Calcium;Mercaptopurine;Methotrexate;Pegaspargase;Thioguanine;Vincristine Sulfate
29 Combination Chemotherapy With or Without Etoposide in Treating Older Patients With Non-Hodgkin's Lymphoma Terminated NCT00060385 Phase 2, Phase 3 CHOP regimen;EPOCH regimen;cyclophosphamide;doxorubicin hydrochloride;etoposide;prednisone;vincristine sulfate
30 Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas Unknown status NCT01805037 Phase 1, Phase 2 brentuximab vedotin
31 High-Dose Chemotherapy Given Together With Peripheral Blood Stem Cell Transplant in Treating Patients With Intestinal T-Cell Lymphoma Unknown status NCT00669812 Phase 2 carmustine;cyclophosphamide;cytarabine;doxorubicin hydrochloride;epirubicin hydrochloride;etoposide;ifosfamide;melphalan;methotrexate;prednisolone;vincristine sulfate
32 Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia Unknown status NCT00002531 Phase 2 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;etoposide;ifosfamide;leucovorin calcium;mercaptopurine;methotrexate;mitoxantrone hydrochloride;prednisolone;teniposide;thioguanine;vincristine sulfate;vindesine
33 Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Unknown status NCT01005758 Phase 2 cyclophosphamide;cytarabine;dexamethasone;doxorubicin hydrochloride;etoposide phosphate;hydrocortisone sodium succinate;imatinib mesylate;mercaptopurine;methotrexate;methylprednisolone;pegaspargase;prednisolone;prednisone;vincristine sulfate
34 Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders Unknown status NCT00008307 Phase 2 cyclosporine;fludarabine phosphate;melphalan;methylprednisolone;mycophenolate mofetil
35 Alemtuzumab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV T-Cell Non-Hodgkin's Lymphoma Unknown status NCT00363090 Phase 1, Phase 2 cyclophosphamide;doxorubicin hydrochloride;prednisone;vincristine sulfate
36 Stem Cell Transplant in Treating Patients With Hematological Cancer or Other Disorders Unknown status NCT00740467 Phase 2 busulfan;cyclophosphamide;cyclosporine;fludarabine phosphate;mycophenolate mofetil
37 Arsenic Trioxide in Treating Patients With Recurrent or Refractory Acute Leukemia, Chronic Myeloide Leukemia, Myelodysplasia, Lymphoma, or Myeloma Unknown status NCT00003885 Phase 2 arsenic trioxide
38 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
39 KW-0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL) Completed NCT01626664 Phase 2 Pralatrexate;gemcitabine plus oxaliplatin;DHAP
40 Phase II Study of the Efficacy and Toxicity of Ontak(Registered Trademark) (Denileukin Diftitox) in the Therapy of Adult T-Cell Leukemia Completed NCT00117845 Phase 2
41 Lenalidomide in HTLV-1 Adult T-Cell Leukemia Completed NCT01274533 Phase 2 Lenalidomide
42 A Phase 2 Study of Lenalidomide in Patients With Relapsed or Recurrent Adult T-cell Leukemia-lymphoma Completed NCT01724177 Phase 2 Lenalidomide
43 Phase II Study of KW-0761 in Subjects With CCR4-positive Adult T-cell Leukemia-lymphoma Completed NCT00920790 Phase 2
44 A Phase II Study Of Imtox-25 In Adults With Refractory/Relapsed Cd25 Positive Adult T Cell Leukemia/Lymphoma Completed NCT01378871 Phase 2 IMTOX-25
45 Campath-1H for Treating Adult T-Cell Leukemia/Lymphoma Completed NCT00061048 Phase 2
46 Multicenter, Randomized, Open-label, Parallel-group Study to Compare mLSG15 + KW-0761 to mLSG15 Completed NCT01173887 Phase 2 VCAP/AMP/VECP(mLSG15)
47 Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma Completed NCT00041327 Phase 2 Etoposide;cyclophosphamide;doxorubicin hydrochloride;lamivudine;prednisone;vincristine sulfate;zidovudine
48 Anti-Tac for Treatment of Leukemia Completed NCT00001941 Phase 1, Phase 2
49 Monoclonal Antibody Therapy in Treating Patients With Leukemia Completed NCT00019227 Phase 1, Phase 2 pentetic acid calcium
50 EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia Lymphoma Completed NCT01000285 Phase 1, Phase 2 Bortezomib;Etoposide;Vincristine;Doxorubicin;Prednisone;Cyclophosphamide;Raltegravir

Search NIH Clinical Center for T-Cell Adult Acute Lymphocytic Leukemia

Genetic Tests for T-Cell Adult Acute Lymphocytic Leukemia

Anatomical Context for T-Cell Adult Acute Lymphocytic Leukemia

MalaCards organs/tissues related to T-Cell Adult Acute Lymphocytic Leukemia:

42
T Cells, Bone Marrow, Kidney, Colon, Myeloid, Lymph Node, Thymus

Publications for T-Cell Adult Acute Lymphocytic Leukemia

Articles related to T-Cell Adult Acute Lymphocytic Leukemia:

(show all 11)
# Title Authors Year
1
Welder's pulmonary hemosiderosis associated with systemic iron overload following exacerbation of acute adult T-cell leukemia/lymphoma. ( 28883221 )
2017
2
Point mutations in TP53 but not in p15(Ink4b) and p16(Ink4a) genes represent poor prognosis factors in acute adult T cell leukemia/lymphoma. ( 25573202 )
2015
3
Bortezomib salvage therapy in refractory acute adult T-cell leukemia/lymphoma. ( 23445368 )
2013
4
Acute adult T-cell leukemia/lymphoma (ATL) presenting with cutaneous purpuric lesions: a rare presentation. ( 21091084 )
2011
5
The importance of flower cells for the early diagnosis of acute adult T-cell leukemia/lymphoma with skin involvement. ( 20001578 )
2010
6
Dual-Positive (CD4+/CD8+) Acute Adult T-Cell Leukemia/Lymphoma Associated with Complex Karyotype and Refractory Hypercalcemia: Case Report and Literature Review. ( 21611103 )
2010
7
Successful treatment of HTLV-1-associated acute adult T-cell leukemia lymphoma by allogeneic bone marrow transplantation: a 12 year follow-up. ( 16966289 )
2006
8
Hemophagocytic syndrome as a presenting sign of transformation of smoldering to acute adult T-cell leukemia/lymphoma: efficacy of anti-retroviral and interferon therapy. ( 15164389 )
2004
9
Unsuccessful association of zidovudine and interferon alpha for acute adult T-cell leukemia lymphoma. ( 10026418 )
1999
10
Experimental acute adult T cell leukemia-lymphoma is associated with thymic atrophy in human T cell leukemia virus type I infection. ( 8600320 )
1996
11
Acute adult T-cell leukemia/lymphoma presenting with florid cutaneous disease. ( 1428453 )
1992

Variations for T-Cell Adult Acute Lymphocytic Leukemia

Expression for T-Cell Adult Acute Lymphocytic Leukemia

Search GEO for disease gene expression data for T-Cell Adult Acute Lymphocytic Leukemia.

Pathways for T-Cell Adult Acute Lymphocytic Leukemia

Pathways related to T-Cell Adult Acute Lymphocytic Leukemia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.54 BCL11B CD2 FOXP3 IL2 INPP5D
2 11.2 CD2 CD5 IL2
3 10.66 BCL11B TOX

GO Terms for T-Cell Adult Acute Lymphocytic Leukemia

Biological processes related to T-Cell Adult Acute Lymphocytic Leukemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 natural killer cell activation GO:0030101 9.43 CD2 IL2
2 regulation of regulatory T cell differentiation GO:0045589 9.4 FOXP3 IL2
3 negative regulation of immune response GO:0050777 9.37 FOXP3 INPP5D
4 positive regulation of regulatory T cell differentiation GO:0045591 9.32 FOXP3 IL2
5 cell recognition GO:0008037 9.26 CADM1 CD5
6 negative regulation of T-helper 17 cell differentiation GO:2000320 9.16 FOXP3 IL2
7 negative regulation of lymphocyte proliferation GO:0050672 8.96 FOXP3 IL2
8 negative regulation of cytokine biosynthetic process GO:0042036 8.62 FOXP3 TIA1

Sources for T-Cell Adult Acute Lymphocytic Leukemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
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75 UMLS via Orphanet
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