MCID: TCR004
MIFTS: 13

Tacrolimus Dose Selection

Categories: Rare diseases

Aliases & Classifications for Tacrolimus Dose Selection

MalaCards integrated aliases for Tacrolimus Dose Selection:

Name: Tacrolimus Dose Selection 60

Classifications:



External Ids:

Orphanet 60 ORPHA241043

Summaries for Tacrolimus Dose Selection

MalaCards based summary : Tacrolimus Dose Selection is related to clopidogrel resistance. Among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Paroxetine Pathway, Pharmacokinetics.

Related Diseases for Tacrolimus Dose Selection

Diseases related to Tacrolimus Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 clopidogrel resistance 9.5 CYP3A4 CYP3A5

Symptoms & Phenotypes for Tacrolimus Dose Selection

Drugs & Therapeutics for Tacrolimus Dose Selection

Search Clinical Trials , NIH Clinical Center for Tacrolimus Dose Selection

Genetic Tests for Tacrolimus Dose Selection

Anatomical Context for Tacrolimus Dose Selection

Publications for Tacrolimus Dose Selection

Variations for Tacrolimus Dose Selection

Expression for Tacrolimus Dose Selection

Search GEO for disease gene expression data for Tacrolimus Dose Selection.

Pathways for Tacrolimus Dose Selection

Pathways related to Tacrolimus Dose Selection according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.26 CYP3A4 CYP3A5
2
Show member pathways
11.64 CYP3A4 CYP3A5
3
Show member pathways
11.58 CYP3A4 CYP3A5
4
Show member pathways
11.31 CYP3A4 CYP3A5
5
Show member pathways
11.28 CYP3A4 CYP3A5
6
Show member pathways
11.19 CYP3A4 CYP3A5
7 11.14 CYP3A4 CYP3A5
8
Show member pathways
11 CYP3A4 CYP3A5
9 10.87 CYP3A4 CYP3A5
10 10.68 CYP3A4 CYP3A5
11 10.43 CYP3A4 CYP3A5
12 10.33 CYP3A4 CYP3A5
13 10.07 CYP3A4 CYP3A5
14 9.62 CYP3A4 CYP3A5

GO Terms for Tacrolimus Dose Selection

Cellular components related to Tacrolimus Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular membrane-bounded organelle GO:0043231 8.96 CYP3A4 CYP3A5
2 organelle membrane GO:0031090 8.62 CYP3A4 CYP3A5

Biological processes related to Tacrolimus Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.4 CYP3A4 CYP3A5
2 steroid metabolic process GO:0008202 9.37 CYP3A4 CYP3A5
3 xenobiotic metabolic process GO:0006805 9.32 CYP3A4 CYP3A5
4 oxidative demethylation GO:0070989 9.26 CYP3A4 CYP3A5
5 drug catabolic process GO:0042737 9.16 CYP3A4 CYP3A5
6 lipid hydroxylation GO:0002933 8.96 CYP3A4 CYP3A5
7 alkaloid catabolic process GO:0009822 8.62 CYP3A4 CYP3A5

Molecular functions related to Tacrolimus Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.43 CYP3A4 CYP3A5
2 heme binding GO:0020037 9.4 CYP3A4 CYP3A5
3 iron ion binding GO:0005506 9.37 CYP3A4 CYP3A5
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.32 CYP3A4 CYP3A5
5 monooxygenase activity GO:0004497 9.26 CYP3A4 CYP3A5
6 oxygen binding GO:0019825 9.16 CYP3A4 CYP3A5
7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.96 CYP3A4 CYP3A5
8 estrogen 16-alpha-hydroxylase activity GO:0101020 8.62 CYP3A4 CYP3A5

Sources for Tacrolimus Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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