MCID: TCT002
MIFTS: 21

Tactile Agnosia

Categories: Eye diseases, Mental diseases

Aliases & Classifications for Tactile Agnosia

MalaCards integrated aliases for Tactile Agnosia:

Name: Tactile Agnosia 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:0060151
UMLS 74 C0234505

Summaries for Tactile Agnosia

Disease Ontology : 12 An agnosia that is a loss of the ability to recognize or identify objects by touch alone.

MalaCards based summary : Tactile Agnosia is related to astereognosia and agnosia, and has symptoms including visual agnosia An important gene associated with Tactile Agnosia is SACS (Sacsin Molecular Chaperone), and among its related pathways/superpathways are Notch signaling pathway (KEGG) and Wnt / Hedgehog / Notch. Affiliated tissues include eye, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 77 Astereognosis (or tactile agnosia if only one hand is affected) is the inability to identify an object... more...

Related Diseases for Tactile Agnosia

Diseases related to Tactile Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 astereognosia 12.1
2 agnosia 10.7
3 aphasia 10.1
4 alexia 10.1

Symptoms & Phenotypes for Tactile Agnosia

UMLS symptoms related to Tactile Agnosia:


visual agnosia

GenomeRNAi Phenotypes related to Tactile Agnosia according to GeneCards Suite gene sharing:

27 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 9.75 BMP7 NUMB
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-109 9.75 BMP7
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.75 BMP7
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.75 IKBKG
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.75 NUMB
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-181 9.75 BMP7
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.75 IKBKG
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.75 NUMB
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.75 BMP7
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.75 BMP7 IKBKG
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.75 BMP7 IKBKG
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.75 BMP7
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-86 9.75 BMP7
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 9.75 BMP7
15 Decreased homologous recombination repair frequency GR00151-A-1 8.96 BMP7 SACS

MGI Mouse Phenotypes related to Tactile Agnosia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.8 BMP7 IKBKG NUMB

Drugs & Therapeutics for Tactile Agnosia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Dry Needling in Chronic Neck Pain. Recruiting NCT03844802 Not Applicable

Search NIH Clinical Center for Tactile Agnosia

Genetic Tests for Tactile Agnosia

Anatomical Context for Tactile Agnosia

MalaCards organs/tissues related to Tactile Agnosia:

42
Eye

Publications for Tactile Agnosia

Articles related to Tactile Agnosia:

(show all 15)
# Title Authors Year
1
Pure associative tactile agnosia for the left hand: clinical and anatomo-functional correlations. ( 25046697 )
2014
2
Analysis of lesions in patients with unilateral tactile agnosia using cytoarchitectonic probabilistic maps. ( 18636551 )
2009
3
A case of tactile agnosia with a lesion restricted to the post-central gyrus. ( 19127044 )
2008
4
Left hand tactile agnosia after posterior callosal lesion. ( 18589409 )
2008
5
Braille alexia: an apperceptive tactile agnosia? ( 17635985 )
2007
6
Hierarchical versus parallel processing in tactile object recognition: a behavioural-neuroanatomical study of aperceptive tactile agnosia. ( 12390978 )
2002
7
Pure tactile agnosia. ( 20945214 )
2001
8
Bilateral tactile agnosia: a case report. ( 9669103 )
1998
9
Tactile agnosia. Underlying impairment and implications for normal tactile object recognition. ( 8673499 )
1996
10
Tactile agnosia. Casuistic evidence and theoretical remarks on modality-specific meaning representations and sensorimotor integration. ( 8931580 )
1996
11
The nature of tactile agnosia: a case study. ( 8084412 )
1994
12
Tactile agnosia and tactile aphasia: symptomatological and anatomical differences. ( 1382919 )
1992
13
&amp;quot;Numb, clumsy hands&amp;quot; and tactile agnosia secondary to high cervical spondylotic myelopathy: a clinical and electrophysiological correlation. ( 1481650 )
1992
14
What has been rediscovered in &amp;quot;Rediscovering tactile agnosia&amp;quot;? ( 1994140 )
1991
15
Rediscovering tactile agnosia. ( 1994134 )
1991

Variations for Tactile Agnosia

Expression for Tactile Agnosia

Search GEO for disease gene expression data for Tactile Agnosia.

Pathways for Tactile Agnosia

Pathways related to Tactile Agnosia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.49 IKBKG NUMB
2 10.88 BMP7 NUMB

GO Terms for Tactile Agnosia

Sources for Tactile Agnosia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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