MCID: TFR002
MIFTS: 20

Tafro Syndrome

Categories: Blood diseases, Bone diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Tafro Syndrome

MalaCards integrated aliases for Tafro Syndrome:

Name: Tafro Syndrome 59
Thrombocytopenia-Anasarca-Fever-Renal Insufficiency-Organomegaly Syndrome 59

Characteristics:

Orphanet epidemiological data:

59
tafro syndrome
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adolescent,Adult,Elderly; Age of death: adult,elderly;

Classifications:



External Ids:

Orphanet 59 ORPHA457077
ICD10 via Orphanet 34 M35.8

Summaries for Tafro Syndrome

MalaCards based summary : Tafro Syndrome, also known as thrombocytopenia-anasarca-fever-renal insufficiency-organomegaly syndrome, is related to thrombocytopenia and multicentric castleman disease. An important gene associated with Tafro Syndrome is CXCL10 (C-X-C Motif Chemokine Ligand 10). Affiliated tissues include bone, kidney and endothelial.

Related Diseases for Tafro Syndrome

Diseases related to Tafro Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 thrombocytopenia 10.3
2 multicentric castleman disease 10.3
3 castleman disease 10.3
4 myelofibrosis 10.1
5 glomerulonephritis 10.1
6 membranoproliferative glomerulonephritis 10.1
7 systemic lupus erythematosus 9.9
8 anemia, autoimmune hemolytic 9.9
9 sjogren syndrome 9.9
10 b-cell lymphomas 9.9
11 diffuse large b-cell lymphoma 9.9
12 hemangioma 9.9
13 hemolytic anemia 9.9
14 lymphoma 9.9
15 cardiac arrest 9.9
16 respiratory failure 9.9
17 disseminated intravascular coagulation 9.9
18 microcytic anemia 9.9
19 nephrotic syndrome 9.9
20 patulous eustachian tube 9.9
21 glomeruloid hemangioma 9.9
22 lupus erythematosus 9.9
23 cholangitis 9.9

Graphical network of the top 20 diseases related to Tafro Syndrome:



Diseases related to Tafro Syndrome

Symptoms & Phenotypes for Tafro Syndrome

Drugs & Therapeutics for Tafro Syndrome

Search Clinical Trials , NIH Clinical Center for Tafro Syndrome

Genetic Tests for Tafro Syndrome

Anatomical Context for Tafro Syndrome

MalaCards organs/tissues related to Tafro Syndrome:

41
Bone, Kidney, Endothelial, Liver, B Cells, Bone Marrow

Publications for Tafro Syndrome

Articles related to Tafro Syndrome:

(show top 50) (show all 72)
# Title Authors Year
1
Multiple haemangiomas in TAFRO syndrome with atypical features of glomeruloid and epithelioid haemangiomas. ( 29952292 )
2018
2
The clinicopathological comparison among nodal cases of idiopathic multicentric Castleman disease with and without TAFRO syndrome. ( 29684500 )
2018
3
TAFRO syndrome with refractory thrombocytopenia responding to tocilizumab and romiplostim: a case report. ( 29468524 )
2018
4
High proportion of TAFRO syndrome in Thai adult Castleman's disease patients: a 10-year experience. ( 29464312 )
2018
5
Membranoproliferative glomerulonephritis-like findings for TAFRO syndrome, associated with an anterior mediastinal tumor: A case report. ( 29901607 )
2018
6
A superelderly case of TAFRO syndrome treated effectively using corticosteroid hormones. ( 29636931 )
2018
7
A comparison of TAFRO syndrome between Japanese and non-Japanese cases: a case report and literature review. ( 28956126 )
2018
8
TAFRO Syndrome. ( 29157612 )
2018
9
Remission of Refractory Ascites and Discontinuation of Hemodialysis after Additional Rituximab to Long-term Glucocorticoid Therapy in a Patient with TAFRO Syndrome. ( 29321413 )
2018
10
TAFRO syndrome: current perspectives. ( 29403325 )
2018
11
Thrombotic microangiopathy on kidney biopsy in a patient with TAFRO syndrome. ( 29766467 )
2018
12
Successful treatment of refractory TAFRO syndrome with elevated vascular endothelial growth factor using thyroxine supplements. ( 29636932 )
2018
13
Successful treatment with tacrolimus in TAFRO syndrome: two case reports and literature review. ( 29879072 )
2018
14
Serial Manifestation of Acute Kidney Injury and Nephrotic Syndrome in a Patient with TAFRO syndrome. ( 29877281 )
2018
15
Glomeruloid hemangioma associated with TAFRO syndrome. ( 29702119 )
2018
16
Renal histology in a patient with TAFRO Syndrome: A case report. ( 29626596 )
2018
17
An autopsy case of TAFRO syndrome with membranoproliferative glomerulonephritis-like lesions. ( 30244358 )
2018
18
Tafro syndrome: Critical review for clinicians and pathologists. ( 29958635 )
2018
19
Successful rituximab treatment of TAFRO syndrome with pathological findings of glomerular endothelial damage. ( 30009125 )
2018
20
A case report of TAFRO syndrome successfully treated by immunosuppressive therapies with plasma exchange. ( 30054706 )
2018
21
TAFRO Syndrome - A Specific Subtype of Castleman's Disease in China. ( 30058586 )
2018
22
FDG PET/CT Findings in TAFRO Syndrome. ( 30222681 )
2018
23
The first case of thrombocytopenia, anasarca, fever, renal impairment or reticulin fibrosis, and organomegaly (TAFRO) syndrome with unilateral adrenal necrosis: a case report. ( 30293532 )
2018
24
A life-threatening case of TAFRO syndrome with dramatic response to tocilizumab, rituximab, and pulse steroids: The first case report in Latin America. ( 28353560 )
2017
25
Cardiac arrest caused by rapidly increasing ascites in a patient with TAFRO syndrome: a case report. ( 29123888 )
2017
26
TAFRO Syndrome with Disseminated Intravascular Coagulation Successfully Treated with Tocilizumab and Recombinant Thrombomodulin. ( 29279488 )
2017
27
Clinicopathological features of progressive renal involvement in TAFRO syndrome: A case report and literature review. ( 28984775 )
2017
28
Successful treatment by tocilizumab without steroid in a very severe case of TAFRO syndrome. ( 28509137 )
2017
29
SjAPgren's syndrome manifesting as clinicopathological features of TAFRO syndrome: A case report. ( 29390349 )
2017
30
TAFRO syndrome: New subtype of idiopathic multicentric Castleman disease. ( 28135567 )
2017
31
Two Cases of Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome with High Serum Procalcitonin Levels, Including the First Case Complicated with Adrenal Hemorrhaging. ( 28502946 )
2017
32
Neuro-ophthalmological findings in TAFRO syndrome in a patient from South America, a variant of multicentric Castleman's disease. ( 28752346 )
2017
33
CT findings in 11 patients with TAFRO syndrome: a variant of multicentric Castleman's disease. ( 28629605 )
2017
34
Castleman's disease with TAFRO syndrome: a case report from Syria. ( 28580156 )
2017
35
Tocilizumab-resistant TAFRO Syndrome Complicated by Type II Respiratory Failure. ( 29021431 )
2017
36
Characterization of patients with systemic lupus erythematosus who meet the diagnostic criteria for TAFRO syndrome. ( 28820362 )
2017
37
Elevated serum interferon I^-induced protein 10 kDa is associated with TAFRO syndrome. ( 28205564 )
2017
38
TAFRO Syndrome in Caucasians: A Case Report and Review of the Literature. ( 29018798 )
2017
39
Two patients with TAFRO syndrome exhibiting strikingly similar anterior mediastinal lesions with predominantly fat attenuation on chest computed tomography. ( 28274535 )
2017
40
Successful Treatment of TAFRO Syndrome with Tocilizumab, Prednisone, and Cyclophosphamide. ( 28781319 )
2017
41
Diffuse Large B-cell Lymphoma during Corticosteroid Therapy for TAFRO Syndrome. ( 27725549 )
2016
42
Magnetic resonance imaging of bone marrow for TAFRO syndrome. ( 27825275 )
2016
43
Aggressive TAFRO syndrome with reversible cardiomyopathy successfully treated with combination chemotherapy. ( 27245076 )
2016
44
A case of TAFRO syndrome, a variant of multicentric Castleman's disease, successfully treated with corticosteroid and cyclosporine A. ( 27413814 )
2016
45
TAFRO Syndrome Associated with EBV and Successful Triple Therapy Treatment: Case Report and Review of the Literature. ( 27777802 )
2016
46
A case of TAFRO syndrome with a large mediastinal mass treated with debulking surgery. ( 27316721 )
2016
47
Successful treatment of TAFRO syndrome, a variant type of multicentric Castleman disease with thrombotic microangiopathy, with anti-IL-6 receptor antibody and steroids. ( 26980221 )
2016
48
An anterior mediastinal lesion in TAFRO syndrome showing complete remission after glucocorticoid and tocilizumab therapy. ( 27516889 )
2016
49
TAFRO syndrome: An atypical variant of KSHV-negative multicentric Castleman disease. ( 26663467 )
2016
50
Potential value of FDG PET-CT in diagnosis and follow-up of TAFRO syndrome. ( 27853835 )
2016

Variations for Tafro Syndrome

Expression for Tafro Syndrome

Search GEO for disease gene expression data for Tafro Syndrome.

Pathways for Tafro Syndrome

GO Terms for Tafro Syndrome

Sources for Tafro Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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