MCID: TLL001
MIFTS: 13

Tall Cell Variant Papillary Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Tall Cell Variant Papillary Carcinoma

MalaCards integrated aliases for Tall Cell Variant Papillary Carcinoma:

Name: Tall Cell Variant Papillary Carcinoma 12 15
Tall Cell Variant Thyroid Gland Papillary Carcinoma 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7089
NCIt 51 C35558
UMLS 74 C1336695

Summaries for Tall Cell Variant Papillary Carcinoma

MalaCards based summary : Tall Cell Variant Papillary Carcinoma, also known as tall cell variant thyroid gland papillary carcinoma, is related to papillary carcinoma. An important gene associated with Tall Cell Variant Papillary Carcinoma is MET (MET Proto-Oncogene, Receptor Tyrosine Kinase). The drugs Pembrolizumab and Lenvatinib have been mentioned in the context of this disorder. Affiliated tissues include thyroid.

Related Diseases for Tall Cell Variant Papillary Carcinoma

Diseases related to Tall Cell Variant Papillary Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 papillary carcinoma 10.3

Symptoms & Phenotypes for Tall Cell Variant Papillary Carcinoma

Drugs & Therapeutics for Tall Cell Variant Papillary Carcinoma

Drugs for Tall Cell Variant Papillary Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pembrolizumab Approved Phase 2 1374853-91-4
2
Lenvatinib Approved, Investigational Phase 2 417716-92-8
3 Protein Kinase Inhibitors Phase 2
4 Antineoplastic Agents, Immunological Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer Completed NCT01811212 Phase 2 Cabozantinib S-malate
2 Lenvatinib and Pembrolizumab in DTC Recruiting NCT02973997 Phase 2 Lenvatinib

Search NIH Clinical Center for Tall Cell Variant Papillary Carcinoma

Genetic Tests for Tall Cell Variant Papillary Carcinoma

Anatomical Context for Tall Cell Variant Papillary Carcinoma

MalaCards organs/tissues related to Tall Cell Variant Papillary Carcinoma:

42
Thyroid

Publications for Tall Cell Variant Papillary Carcinoma

Articles related to Tall Cell Variant Papillary Carcinoma:

# Title Authors Year
1
Anaplastic Spindle Cell Squamous Carcinoma Arising from Tall Cell Variant Papillary Carcinoma of the Thyroid Gland: A Case Report and Review of the Literature. ( 28484653 )
2017
2
c-Met expression in tall cell variant papillary carcinoma of the thyroid. ( 14508824 )
2003

Variations for Tall Cell Variant Papillary Carcinoma

Cosmic variations for Tall Cell Variant Papillary Carcinoma:

9 (show top 50) (show all 1180)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM6961574 ZFHX3 thyroid,NS,carcinoma,papillary carcinoma c.5539C>T p.Q1847* 16:72797143-72797143 0
2 COSM7339522 ZBTB2 thyroid,NS,carcinoma,papillary carcinoma c.1012C>G p.P338A 6:151366054-151366054 0
3 COSM7339681 XPO1 thyroid,NS,carcinoma,papillary carcinoma c.1801C>G p.Q601E 2:61492121-61492121 0
4 COSM7340098 XPO1 thyroid,NS,carcinoma,papillary carcinoma c.994G>T p.E332* 2:61495508-61495508 0
5 COSM7339812 WT1 thyroid,NS,carcinoma,papillary carcinoma c.494C>G p.S165W 11:32428568-32428568 0
6 COSM6954354 VTCN1 thyroid,NS,carcinoma,papillary carcinoma c.399C>G p.I133M 1:117156620-117156620 0
7 COSM17721 VHL thyroid,NS,carcinoma,papillary carcinoma c.241C>T p.P81S 3:10142088-10142088 0
8 COSM26416 TSHR thyroid,NS,carcinoma,papillary carcinoma c.1867G>T p.A623S 14:81143925-81143925 0
9 COSM26497 TSHR thyroid,NS,carcinoma,papillary carcinoma c.1915C>T p.P639S 14:81143973-81143973 0
10 COSM26449 TSHR thyroid,NS,carcinoma,papillary carcinoma c.1358T>C p.M453T 14:81143416-81143416 0
11 COSM26417 TSHR thyroid,NS,carcinoma,papillary carcinoma c.1868C>T p.A623V 14:81143926-81143926 0
12 COSM26419 TSHR thyroid,NS,carcinoma,papillary carcinoma c.1897G>T p.D633Y 14:81143955-81143955 0
13 COSM7340068 TSHR thyroid,NS,carcinoma,papillary carcinoma c.572C>T p.S191L 14:81096665-81096665 0
14 COSM7339928 TSC2 thyroid,NS,carcinoma,papillary carcinoma c.4760G>A p.C1587Y 16:2086290-2086290 0
15 COSM6918838 TSC2 thyroid,NS,carcinoma,papillary carcinoma c.4468G>C p.E1490Q 16:2084690-2084690 0
16 COSM7340474 TSC2 thyroid,NS,carcinoma,papillary carcinoma c.4433A>T p.D1478V 16:2084655-2084655 0
17 COSM7340359 TRRAP thyroid,NS,carcinoma,papillary carcinoma c.7672A>C p.T2558P 7:98971853-98971853 0
18 COSM7340196 TP53BP1 thyroid,NS,carcinoma,papillary carcinoma c.910G>T p.E304* 15:43477623-43477623 0
19 COSM7340198 TP53BP1 thyroid,NS,carcinoma,papillary carcinoma c.5465G>T p.G1822V 15:43409017-43409017 0
20 COSM10659 TP53 thyroid,NS,carcinoma,papillary carcinoma c.817C>T p.R273C 17:7673803-7673803 0
21 COSM10704 TP53 thyroid,NS,carcinoma,papillary carcinoma c.844C>T p.R282W 17:7673776-7673776 0
22 COSM43951 TP53 thyroid,NS,carcinoma,papillary carcinoma c.643A>G p.S215G 17:7674888-7674888 0
23 COSM11196 TP53 thyroid,NS,carcinoma,papillary carcinoma c.734G>T p.G245V 17:7674229-7674229 0
24 COSM10648 TP53 thyroid,NS,carcinoma,papillary carcinoma c.524G>A p.R175H 17:7675088-7675088 0
25 COSM43723 TP53 thyroid,NS,carcinoma,papillary carcinoma c.398T>C p.M133T 17:7675214-7675214 0
26 COSM10662 TP53 thyroid,NS,carcinoma,papillary carcinoma c.743G>A p.R248Q 17:7674220-7674220 0
27 COSM10758 TP53 thyroid,NS,carcinoma,papillary carcinoma c.659A>G p.Y220C 17:7674872-7674872 0
28 COSM5444226 TP53 thyroid,NS,carcinoma,papillary carcinoma c.96+1G>C p.? 17:7676381-7676381 0
29 COSM44225 TP53 thyroid,NS,carcinoma,papillary carcinoma c.859G>A p.E287K 17:7673761-7673761 0
30 COSM10739 TP53 thyroid,NS,carcinoma,papillary carcinoma c.481G>A p.A161T 17:7675131-7675131 0
31 COSM10654 TP53 thyroid,NS,carcinoma,papillary carcinoma c.637C>T p.R213* 17:7674894-7674894 0
32 COSM44922 TP53 thyroid,NS,carcinoma,papillary carcinoma c.670G>T p.E224* 17:7674861-7674861 0
33 COSM44338 TP53 thyroid,NS,carcinoma,papillary carcinoma c.845G>A p.R282Q 17:7673775-7673775 0
34 COSM44101 TP53 thyroid,NS,carcinoma,papillary carcinoma c.417G>C p.K139N 17:7675195-7675195 0
35 COSM10812 TP53 thyroid,NS,carcinoma,papillary carcinoma c.722C>T p.S241F 17:7674241-7674241 0
36 COSM10660 TP53 thyroid,NS,carcinoma,papillary carcinoma c.818G>A p.R273H 17:7673802-7673802 0
37 COSM10667 TP53 thyroid,NS,carcinoma,papillary carcinoma c.646G>A p.V216M 17:7674885-7674885 0
38 COSM11183 TP53 thyroid,NS,carcinoma,papillary carcinoma c.799C>T p.R267W 17:7673821-7673821 0
39 COSM43801 TP53 thyroid,NS,carcinoma,papillary carcinoma c.716A>C p.N239T 17:7674247-7674247 0
40 COSM43980 TP53 thyroid,NS,carcinoma,papillary carcinoma c.691A>G p.T231A 17:7674272-7674272 0
41 COSM10863 TP53 thyroid,NS,carcinoma,papillary carcinoma c.833C>T p.P278L 17:7673787-7673787 0
42 COSM11114 TP53 thyroid,NS,carcinoma,papillary carcinoma c.528C>G p.C176W 17:7675084-7675084 0
43 COSM44988 TP53 thyroid,NS,carcinoma,papillary carcinoma c.374C>T p.T125M 17:7675995-7675995 0
44 COSM10705 TP53 thyroid,NS,carcinoma,papillary carcinoma c.586C>T p.R196* 17:7674945-7674945 0
45 COSM10731 TP53 thyroid,NS,carcinoma,papillary carcinoma c.707A>G p.Y236C 17:7674256-7674256 0
46 COSM10735 TP53 thyroid,NS,carcinoma,papillary carcinoma c.638G>A p.R213Q 17:7674893-7674893 0
47 COSM10771 TP53 thyroid,NS,carcinoma,papillary carcinoma c.749C>T p.P250L 17:7674214-7674214 0
48 COSM10738 TP53 thyroid,NS,carcinoma,papillary carcinoma c.542G>A p.R181H 17:7675070-7675070 0
49 COSM44310 TP53 thyroid,NS,carcinoma,papillary carcinoma c.738G>A p.M246I 17:7674225-7674225 0
50 COSM11089 TP53 thyroid,NS,carcinoma,papillary carcinoma c.584T>C p.I195T 17:7674947-7674947 0

Expression for Tall Cell Variant Papillary Carcinoma

Search GEO for disease gene expression data for Tall Cell Variant Papillary Carcinoma.

Pathways for Tall Cell Variant Papillary Carcinoma

GO Terms for Tall Cell Variant Papillary Carcinoma

Sources for Tall Cell Variant Papillary Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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