MCID: TNY001
MIFTS: 31

Tanycytic Ependymoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Tanycytic Ependymoma

MalaCards integrated aliases for Tanycytic Ependymoma:

Name: Tanycytic Ependymoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:5504
NCIt 51 C6903
SNOMED-CT 69 57706008
UMLS 74 C1370500

Summaries for Tanycytic Ependymoma

MalaCards based summary : Tanycytic Ependymoma is related to ependymoma and benign ependymoma. An important gene associated with Tanycytic Ependymoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, spinal cord and pineal, and related phenotypes are Increased proliferation and growth/size/body region

Related Diseases for Tanycytic Ependymoma

Diseases related to Tanycytic Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 159)
# Related Disease Score Top Affiliating Genes
1 ependymoma 32.3 GFAP MEN1 NES NF2 SYP
2 benign ependymoma 31.5 GFAP NF2 RBFOX3 SYP
3 neurilemmoma 30.1 GFAP NES NF2 SMARCB1
4 multiple endocrine neoplasia, type i 29.9 CHGA MEN1 SYP
5 subependymoma 29.8 CHGA GFAP NES SYP
6 ganglioglioma 29.4 CHGA GFAP NES SMARCB1 SYP
7 meningioma, radiation-induced 10.4 GFAP NF2
8 desmoplastic infantile ganglioglioma 10.4 GFAP SYP
9 extraventricular neurocytoma 10.4 GFAP SYP
10 lung combined type small cell carcinoma 10.4 GFAP SYP
11 cerebral convexity meningioma 10.4 GFAP NF2
12 intraventricular meningioma 10.4 GFAP NF2
13 clear cell ependymoma 10.4 GFAP SYP
14 chiari malformation 10.4 GFAP SYP
15 cerebral neuroblastoma 10.4 GFAP SYP
16 cornea cancer 10.4 GFAP NF2
17 plexiform schwannoma 10.4 GFAP NF2
18 subependymal glioma 10.4 GFAP SYP
19 spinal cancer 10.4 GFAP NF2
20 pineal gland cancer 10.4 GFAP SYP
21 neurofibromatosis, type iv, of riccardi 10.4
22 melanotic neuroectodermal tumor 10.4 GFAP SYP
23 angiocentric glioma 10.4 GFAP SYP
24 obstructive hydrocephalus 10.4 GFAP SYP
25 chordoid glioma 10.4 GFAP NF2
26 atypical neurofibroma 10.4 GFAP NF2
27 trigeminal nerve neoplasm 10.4 GFAP NF2
28 neurilemmoma of the fifth cranial nerve 10.4 GFAP NF2
29 chondrosarcoma, extraskeletal myxoid 10.4 SMARCB1 SYP
30 malignant ependymoma 10.4 GFAP NF2
31 pineoblastoma 10.4 GFAP SYP
32 papilloma of choroid plexus 10.4 GFAP SYP
33 melanotic medulloblastoma 10.4 GFAP SMARCB1
34 nodular medulloblastoma 10.3 GFAP SMARCB1
35 monosomy 22 10.3 NF2 SMARCB1
36 cystic teratoma 10.3 GFAP SYP
37 schwannomatosis 1 10.3 NF2 SMARCB1
38 extraosseous chondrosarcoma 10.3 SMARCB1 SYP
39 central nervous system benign neoplasm 10.3 GFAP SYP
40 partial motor epilepsy 10.3 RBFOX3 SYP
41 gangliocytoma 10.3 RBFOX3 SYP
42 pilomyxoid astrocytoma 10.3 GFAP SYP
43 rhabdoid cancer 10.3 SMARCB1 SYP
44 sella turcica neoplasm 10.3 RBFOX3 SYP
45 anaplastic ganglioglioma 10.3 GFAP NES
46 tuberculum sellae meningioma 10.3 RBFOX3 SYP
47 central nervous system germ cell tumor 10.3 GFAP NES
48 choroid plexus cancer 10.3 GFAP SMARCB1
49 mandibulofacial dysostosis, guion-almeida type 10.3 KDM6A KMT2D
50 anaplastic ependymoma 10.3 GFAP NF2 SYP

Graphical network of the top 20 diseases related to Tanycytic Ependymoma:



Diseases related to Tanycytic Ependymoma

Symptoms & Phenotypes for Tanycytic Ependymoma

GenomeRNAi Phenotypes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.8 MEN1 NF2 SMARCB1

MGI Mouse Phenotypes related to Tanycytic Ependymoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.86 CHGA GFAP KDM6A KMT2D MEN1 NF2
2 muscle MP:0005369 9.7 CHGA GFAP KDM6A KMT2D MEN1 OLIG2
3 neoplasm MP:0002006 9.43 KDM6A KMT2D MEN1 NF2 OLIG2 SMARCB1
4 nervous system MP:0003631 9.28 CHGA GFAP KDM6A KMT2D MEN1 NF2

Drugs & Therapeutics for Tanycytic Ependymoma

Search Clinical Trials , NIH Clinical Center for Tanycytic Ependymoma

Genetic Tests for Tanycytic Ependymoma

Anatomical Context for Tanycytic Ependymoma

MalaCards organs/tissues related to Tanycytic Ependymoma:

42
Brain, Spinal Cord, Pineal, Kidney, Ovary, Pituitary, Cervix

Publications for Tanycytic Ependymoma

Articles related to Tanycytic Ependymoma:

(show all 41)
# Title Authors Year
1
Extramedullary Tanycytic Ependymoma in a 12-Year-Old Boy. ( 31001044 )
2019
2
Tanycytic ependymoma of filum terminale: Clinical characteristics and surgical outcomes. ( 30546423 )
2018
3
Tanycytic ependymoma of the brain stem, presentations of rare cystic disease variants and review of literature. ( 28884561 )
2018
4
Two Cases of Spinal Tanycytic Ependymoma Associated with Neurofibromatosis Type 2. ( 28345553 )
2017
5
Squash cytology of tanycytic ependymoma: A report of two cases. ( 27879059 )
2017
6
Imaging features of spinal tanycytic ependymoma. ( 26755489 )
2016
7
Tanycytic ependymoma of cervical cord presenting with spontaneous intratumoral hemorrhage. ( 27033310 )
2016
8
Supratentorial tanycytic ependymoma in an adult male: case report and review of literature. ( 25873884 )
2015
9
Spinal tanycytic ependymoma associated with neurofibromatosis type 2. ( 24495349 )
2014
10
Pediatric supratentorial cortical tanycytic ependymoma associated with absence seizures. ( 24569174 )
2014
11
intraventricular tanycytic ependymoma: an uncommon fibrillary variant. ( 24823737 )
2014
12
Mystery case: tanycytic ependymoma of the conus medullaris: a rare cause of low back pain. ( 24960834 )
2014
13
Features of intraventricular tanycytic ependymoma: report of a case and review of literature. ( 25031767 )
2014
14
Vestibular schwannoma or tanycytic ependymoma: Immunohistologic staining reveals. ( 25506503 )
2014
15
Tanycytic ependymoma in a 76-year-old Puerto Rican male. ( 25550817 )
2014
16
A cortical cystic epileptogenic lesion: tanycytic ependymoma. ( 23160807 )
2013
17
Tanycytic ependymoma: a challenging histological diagnosis. ( 23476839 )
2013
18
Tanycytic ependymoma of the filum terminale associated with multiple endocrine neoplasia type 1: first reported case. ( 23562332 )
2013
19
A 40-year-old male with an intraventricular tumor. Combined tanycytic ependymoma and subependymoma. ( 23587142 )
2013
20
Spinal tanycytic ependymoma with diffusion restriction on MRI. ( 22427295 )
2012
21
Tanycytic ependymoma of filum terminale: a case report. ( 22056760 )
2012
22
A rare case of spinal dumbbell tanycytic ependymoma. ( 21270701 )
2011
23
Supratentorial tanycytic ependymoma: an uncommon fibrillary ependymoma variant. ( 21877052 )
2011
24
Spinal cord tanycytic ependymoma associated with neurofibromatosis type 2. ( 20403699 )
2010
25
Rapid spontaneous malignant progression of supratentorial tanycytic ependymoma with sarcomatous features - "Ependymosarcoma". ( 19853384 )
2010
26
Tanycytic ependymoma of the spinal cord with anaplastic cytological features. ( 19408091 )
2009
27
Tanycytic ependymoma of the filum terminale with pleomorphic giant cells. ( 19856219 )
2009
28
Tanycytic ependymoma arising from the right lateral ventricle: a case report and review of the literature. ( 18312548 )
2008
29
Pediatric tanycytic ependymoma of the cauda equina: case report and review of the literature. ( 18401036 )
2008
30
A case of tanycytic ependymoma arising from the cerebral hemisphere. ( 18095125 )
2006
31
A case of cervicomedullary junction tanycytic ependymoma associated with marked cyst formation. ( 18095101 )
2005
32
Intraventricular tanycytic ependymoma: case report and review of the literature. ( 15690137 )
2005
33
Spinal tanycytic ependymoma with hematomyelia--case report--. ( 15782011 )
2005
34
Supratentorial tanycytic ependymoma. ( 15519882 )
2004
35
Tanycytic ependymoma of the spinal cord. Case report and review of the literature. ( 14735006 )
2003
36
Intraoperative diagnosis of tanycytic ependymoma: pitfalls and differential diagnosis. ( 11285628 )
2001
37
Tanycytic ependymoma in association with neurofibromatosis type 2. ( 11430494 )
2001
38
Spinal tanycytic ependymoma associated with neurofibromatosis type 2--case report. ( 11760389 )
2001
39
Ganglioglioma with a tanycytic ependymoma as the glial component. ( 10663975 )
2000
40
The tanycytic ependymoma of the lateral ventricle: case report. ( 10667826 )
1999
41
Tanycytic ependymoma. ( 9090024 )
1997

Variations for Tanycytic Ependymoma

Expression for Tanycytic Ependymoma

Search GEO for disease gene expression data for Tanycytic Ependymoma.

Pathways for Tanycytic Ependymoma

Pathways related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.79 GFAP NF2 RBFOX3 SYP
2 10.82 GFAP NES OLIG2 SYP

GO Terms for Tanycytic Ependymoma

Cellular components related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MLL3/4 complex GO:0044666 8.96 KDM6A KMT2D
2 histone methyltransferase complex GO:0035097 8.8 KDM6A KMT2D MEN1

Biological processes related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.46 NES OLIG2 RBFOX3 SMARCB1
2 beta-catenin-TCF complex assembly GO:1904837 9.26 KMT2D MEN1
3 histone H3-K4 methylation GO:0051568 8.96 KDM6A KMT2D
4 chromatin organization GO:0006325 8.92 KDM6A KMT2D MEN1 SMARCB1

Molecular functions related to Tanycytic Ependymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 histone-lysine N-methyltransferase activity GO:0018024 8.62 KMT2D MEN1

Sources for Tanycytic Ependymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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