MCID: TRS001
MIFTS: 34

Tarsal Tunnel Syndrome

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Tarsal Tunnel Syndrome

MalaCards integrated aliases for Tarsal Tunnel Syndrome:

Name: Tarsal Tunnel Syndrome 12 77 54 45 15 17 74
Neuropathy of the Posterior Tibial Nerve and Its Branches 54
Posterior Tibial Nerve Neuralgia 54

Classifications:



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Disease Ontology 12 DOID:12526
ICD9CM 36 355.5
MeSH 45 D013641
NCIt 51 C85183
SNOMED-CT 69 47374004
ICD10 34 G57.5 G57.50
UMLS 74 C0039319

Summaries for Tarsal Tunnel Syndrome

NIH Rare Diseases : 54 Tarsal tunnel syndrome is a nerve disorder that is characterized by pain in the ankle, foot, and toes. This condition is caused by compression of the posterior tibial nerve, which runs through a canal near the heel into the sole of the foot. When tissues around this nerve become inflamed, they can press on the nerve and cause the pain associated with tarsal tunnel syndrome.

MalaCards based summary : Tarsal Tunnel Syndrome, also known as neuropathy of the posterior tibial nerve and its branches, is related to neurilemmoma and neuropathy. An important gene associated with Tarsal Tunnel Syndrome is CRYGB (Crystallin Gamma B), and among its related pathways/superpathways are Neuroscience and Angiogenesis (CST). Affiliated tissues include testes, t cells and pituitary.

Wikipedia : 77 Tarsal tunnel syndrome (TTS), also known as posterior tibial neuralgia, is a compression neuropathy and... more...

Related Diseases for Tarsal Tunnel Syndrome

Diseases related to Tarsal Tunnel Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 neurilemmoma 10.4
2 neuropathy 10.4
3 rheumatoid arthritis 10.3
4 arthritis 10.3
5 tarsal coalition 10.2
6 sarcoma 10.2
7 neurofibroma 10.2
8 spondyloarthropathy 1 10.1
9 sarcoma, synovial 10.1
10 muscle hypertrophy 10.1
11 lymphoma 10.1
12 radiculopathy 10.1
13 spondylitis 10.1
14 fasciitis 10.1
15 plantar fasciitis 10.1
16 osteochondroma 10.1
17 al amyloidosis 10.1 B2M TTR
18 amyloidosis 10.1 B2M TTR
19 median rhomboid glossitis 10.1 B2M TTR
20 amyloid tumor 10.1 B2M TTR
21 hereditary amyloidosis 10.1 B2M TTR
22 amyloidosis aa 10.0 B2M TTR
23 retinitis pigmentosa 7 10.0 B2M TTR
24 osteoporosis 10.0
25 peroneal nerve, accessory deep 10.0
26 reflex sympathetic dystrophy 10.0
27 human venous malformation 10.0
28 leukemia 10.0
29 osteomyelitis 10.0
30 spondyloarthropathy 10.0
31 diabetic polyneuropathy 10.0
32 gout 10.0
33 hypermobility syndrome 10.0
34 polyneuropathy 10.0
35 algoneurodystrophy 10.0
36 hypothyroidism 10.0
37 neuritis 10.0
38 exostosis 10.0
39 extraosseous osteosarcoma 10.0
40 plexiform neurofibroma 10.0
41 peripheral nervous system disease 10.0
42 myeloid sarcoma 10.0
43 hypermobile ehlers-danlos syndrome 10.0
44 synovial chondromatosis 10.0
45 amyloidosis, familial visceral 10.0 B2M TTR
46 oral candidiasis 10.0 B2M SKAP2
47 carpal tunnel syndrome 10.0 B2M TTR
48 sella turcica neoplasm 9.9 POMC TTR
49 tuberculum sellae meningioma 9.9 POMC TTR
50 thyroid crisis 9.9 POMC TTR

Graphical network of the top 20 diseases related to Tarsal Tunnel Syndrome:



Diseases related to Tarsal Tunnel Syndrome

Symptoms & Phenotypes for Tarsal Tunnel Syndrome

Drugs & Therapeutics for Tarsal Tunnel Syndrome

Search Clinical Trials , NIH Clinical Center for Tarsal Tunnel Syndrome

Cochrane evidence based reviews: tarsal tunnel syndrome

Genetic Tests for Tarsal Tunnel Syndrome

Anatomical Context for Tarsal Tunnel Syndrome

MalaCards organs/tissues related to Tarsal Tunnel Syndrome:

42
Testes, T Cells, Pituitary, Thyroid, Myeloid

Publications for Tarsal Tunnel Syndrome

Articles related to Tarsal Tunnel Syndrome:

(show top 50) (show all 285)
# Title Authors Year
1
Ultrasound facilitates the diagnosis of tarsal tunnel syndrome: intraneural ganglion cyst of the tibial nerve. ( 30019288 )
2019
2
Ultrasound-guided decompression surgery of the tarsal tunnel: a novel technique for the proximal tarsal tunnel syndrome-Part II. ( 30382330 )
2019
3
Ultrasound-guided decompression surgery of the distal tarsal tunnel: a novel technique for the distal tarsal tunnel syndrome-part III. ( 30798383 )
2019
4
A Case Report and Literature Review: Intraneural Ganglion Cyst Causing Tarsal Tunnel Syndrome. ( 31053383 )
2019
5
Recurrence of acute myelogenous leukemia with granulocytic sarcoma-associated tarsal tunnel syndrome in an elderly patient. ( 27452740 )
2018
6
Venous malformation as source of a tarsal tunnel syndrome: treat the source or the cause of the complaints? A case report. ( 28454504 )
2018
7
Posterior Tibial Nerve Lymphoma Presenting as Tarsal Tunnel Syndrome: A Case Report. ( 28847643 )
2018
8
Tarsal Tunnel Syndrome Caused by a Schwannoma of the Posterior Tibial Nerve. ( 29463943 )
2018
9
Value of Motor Nerve Conduction Studies in the Diagnosis of Idiopathic Tarsal Tunnel Syndrome: A Single-center Prospective Observational Study from India. ( 29720796 )
2018
10
Recurrence of Extranodal Natural Killer/T-cell Lymphoma Presenting as Tarsal Tunnel Syndrome. ( 29883499 )
2018
11
Bilateral Tarsal Tunnel Syndrome. ( 29909848 )
2018
12
Tarsal tunnel syndrome caused by an uncommon ossicle of the talus: A case report. ( 29923985 )
2018
13
Schwannoma of the Posterior Tibial Nerve Presenting as Tarsal Tunnel Syndrome: A Case Report with Emphasis on the Role of Microscope during Surgery. ( 30155329 )
2018
14
Extra-tunnel Compression Mimicking Tarsal Tunnel Syndrome: Ultrasound Imaging for a Plantar Ganglion Cyst. ( 30534667 )
2018
15
Plexiform Neurofibroma of the Posterior Tibial Nerve Misdiagnosed as Proximal Tarsal Tunnel Syndrome: A Case Report. ( 29497706 )
2018
16
Recurrent Extra- and Intra-articular Synovial Chondromatosis of the Ankle with Tarsal Tunnel Syndrome: A Rare Case Report. ( 28819605 )
2017
17
Bilateral tarsal tunnel syndrome attributed to bilateral fibrous tarsal coalition and symmetrical hypertrophy of the sustentaculum tali. ( 28883007 )
2017
18
Unusual Cause of Anterior Tarsal Tunnel Syndrome: Ultrasound Findings. ( 28039874 )
2017
19
Tarsal Tunnel Syndrome Due To Three Different Types of Ganglion During a 12-Year Period: A Case Report. ( 28073652 )
2017
20
Diagnosing Bilateral Tarsal Tunnel Syndrome. ( 28602876 )
2017
21
Tarsal tunnel syndrome: still more opinions than evidence. Status of the art. ( 28664501 )
2017
22
Schwannoma and neurofibroma of the posterior tibial nerve presenting as tarsal tunnel syndrome: review of the literature with two case reports. ( 28624667 )
2017
23
Bilateral posterior tarsal tunnel syndrome caused by accessory flexor digitorum longus; case report and surgical technique. ( 26655210 )
2017
24
Extensive Osteochondroma of Talus Presenting as Tarsal Tunnel Syndrome: Report of a case and Literature Review. ( 27517075 )
2016
25
Ultrasound-Guided Tibial Nerve Block for Definitive Treatment of Tarsal Tunnel Syndrome in a Pediatric Patient. ( 27093282 )
2016
26
The Impact of Tarsal Tunnel Syndrome on Cold Sensation in the Pedal Extremities. ( 27150642 )
2016
27
Ultrasound in tarsal tunnel syndrome: Correct diagnosis for appropriate treatment. ( 27610548 )
2016
28
The prevalence of tarsal tunnel syndrome in patients with lumbosacral radiculopathy. ( 26407567 )
2016
29
Tarsal Tunnel Syndrome Secondary to an Unreported Ossicle of the Talus: A Case Report. ( 25441278 )
2016
30
Usefulness of 99mTc-hydroxymethylene-diphosphonate single photon emission computed tomography/computed tomography hybrid imaging in the study of tarsal tunnel syndrome. ( 26026922 )
2016
31
Accessory Soleus: A Case Report of Exertional Compartment and Tarsal Tunnel Syndrome Associated With an Accessory Soleus Muscle. ( 26361954 )
2016
32
Nerve ultrasound in electrophysiologically verified tarsal tunnel syndrome. ( 26562220 )
2016
33
Proposed Sonographic Criteria for the Diagnosis of Idiopathic Tarsal Tunnel Syndrome. ( 26705883 )
2016
34
Tarsal tunnel syndrome after total ankle replacement--a report of 3 cases. ( 26751913 )
2016
35
Endoscopic tarsal tunnel syndrome surgery using the Universal Subcutaneous Endoscope system. ( 29264253 )
2016
36
Tarsal tunnel syndrome masked by painful diabetic polyneuropathy. ( 26333036 )
2015
37
Posterior tibial vein aneurysm presenting as tarsal tunnel syndrome. ( 25199522 )
2015
38
Acute Posterior Tarsal Tunnel Syndrome Caused by Gouty Tophus. ( 25205680 )
2015
39
Results of surgical treatment of tarsal tunnel syndrome. ( 25682403 )
2015
40
A case of acute tarsal tunnel syndrome following lateralizing calcaneal osteotomy. ( 25682414 )
2015
41
Tarsal tunnel syndrome associated with a perforating branch from posterior tibial artery: a case report. ( 25682417 )
2015
42
Flexor digitorum accessorius causing tarsal tunnel syndrome in a paediatric patient: A case report and review of the literature. ( 25937423 )
2015
43
Bilateral tarsal tunnel syndrome related to intense cycling activity: proposal of a multimodal diagnostic approach. ( 26044912 )
2015
44
Anterior Tarsal Tunnel Syndrome With Thrombosed Dorsalis Pedis Artery: A Case Report. ( 26064866 )
2015
45
Treatment of anterior tarsal tunnel syndrome through an endoscopic or open technique. ( 26209470 )
2015
46
Anatomical characteristics of the flexor digitorum accessorius longus muscle and their relevance to tarsal tunnel syndrome a systematic review. ( 26218158 )
2015
47
Tarsal tunnel syndrome-A narrative literature review. ( 26546070 )
2015
48
Bilateral anterior tarsal tunnel syndrome variant secondary to extensor hallucis brevis muscle hypertrophy in a ballet dancer: a case report. ( 25457672 )
2014
49
Tarsal tunnel syndrome secondary to suture material within the tibial artery: a sonographic diagnosis. ( 23370591 )
2014
50
Tarsal tunnel syndrome secondary to schwannoma of the posterior tibial nerve. ( 23954095 )
2014

Variations for Tarsal Tunnel Syndrome

Expression for Tarsal Tunnel Syndrome

Search GEO for disease gene expression data for Tarsal Tunnel Syndrome.

Pathways for Tarsal Tunnel Syndrome

Pathways related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.67 NOTCH1 POMC TNC
2 11.11 NOTCH1 TNC
3 9.85 NOTCH1 TNC

GO Terms for Tarsal Tunnel Syndrome

Cellular components related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.02 B2M NOTCH1 POMC TNC TTR

Biological processes related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.13 B2M TNC TTR
2 prostate gland epithelium morphogenesis GO:0060740 8.62 NOTCH1 TNC

Molecular functions related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 POMC TTR

Sources for Tarsal Tunnel Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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