MCID: TRS001
MIFTS: 30

Tarsal Tunnel Syndrome

Categories: Muscle diseases, Neuronal diseases, Rare diseases
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Aliases & Classifications for Tarsal Tunnel Syndrome

MalaCards integrated aliases for Tarsal Tunnel Syndrome:

Name: Tarsal Tunnel Syndrome 11 19 75 43 14 16 71 31 33
Neuropathy of the Posterior Tibial Nerve and Its Branches 19
Compression of Posterior Tibial Nerve in Tarsal Tunnel 33
Posterior Tibial Nerve Neuralgia 19

Classifications:



External Ids:

Disease Ontology 11 DOID:12526
ICD9CM 34 355.5
MeSH 43 D013641
NCIt 49 C85183
SNOMED-CT 68 155077008
ICD10 31 G57.5
ICD11 33 854657246
UMLS 71 C0039319

Summaries for Tarsal Tunnel Syndrome

GARD: 19 Tarsal tunnel syndrome is a nerve disorder that is characterized by pain in the ankle, foot, and toes. This condition is caused by compression of the posterior tibial nerve, which runs through a canal near the heel into the sole of the foot. When tissues around this nerve become inflamed, they can press on the nerve and cause the pain associated with Tarsal tunnel syndrome.

MalaCards based summary: Tarsal Tunnel Syndrome, also known as neuropathy of the posterior tibial nerve and its branches, is related to tibial neuropathy and nerve compression syndrome. An important gene associated with Tarsal Tunnel Syndrome is CCNL1 (Cyclin L1). Affiliated tissues include bone.

Wikipedia: 75 Tarsal tunnel syndrome (TTS) is a compression neuropathy and painful foot condition in which the tibial... more...

Related Diseases for Tarsal Tunnel Syndrome

Diseases related to Tarsal Tunnel Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 tibial neuropathy 27.7 TNC SNORD22 PAGE2 MPZ MED31 GNPTG
2 nerve compression syndrome 10.9
3 neuropathy, hereditary, with liability to pressure palsies 10.8
4 neurilemmoma 10.7
5 paresthesia 10.6
6 neuropathy 10.5
7 carpal tunnel syndrome 10.5
8 varicose veins 10.5
9 mononeuropathy of the median nerve, mild 10.5
10 peripheral nervous system disease 10.5
11 tenosynovitis 10.5
12 exostosis 10.4
13 fasciitis 10.4
14 plantar fasciitis 10.4
15 tarsal coalition 10.4
16 radiculopathy 10.4
17 spondyloarthropathy 1 10.4
18 gout 10.4
19 synovitis 10.4
20 lipomatosis, multiple 10.3
21 neuritis 10.3
22 spondylitis 10.3
23 neurofibroma 10.3
24 osteochondroma 10.3
25 reflex sympathetic dystrophy 10.2
26 polyneuropathy 10.2
27 complex regional pain syndrome 10.2
28 pfeiffer syndrome 10.2
29 leprosy 3 10.2
30 sarcoma, synovial 10.2
31 microvascular complications of diabetes 1 10.2
32 muscle hypertrophy 10.2
33 tendinitis 10.2
34 sarcoma 10.2
35 diabetic polyneuropathy 10.2
36 hypothyroidism 10.2
37 neuroma 10.2
38 chronic kidney disease 10.2
39 diabetic neuropathy 10.2
40 synovial chondromatosis 10.2
41 epidural spinal canal neoplasm 10.0 PAGE2 ENTREP3
42 exostoses, multiple, type i 10.0
43 guillain-barre syndrome, familial 10.0
44 enchondromatosis, multiple, ollier type 10.0
45 osteoporosis 10.0
46 peroneal nerve, accessory deep 10.0
47 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.0
48 scleroderma, familial progressive 10.0
49 thrombophilia due to thrombin defect 10.0
50 down syndrome 10.0

Graphical network of the top 20 diseases related to Tarsal Tunnel Syndrome:



Diseases related to Tarsal Tunnel Syndrome

Symptoms & Phenotypes for Tarsal Tunnel Syndrome

Drugs & Therapeutics for Tarsal Tunnel Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 What is the Relationship Between Tarsal Tunnel Syndrome and Foot Pain in Fibromyalgia Patients Completed NCT05135572
2 The Effectiveness of Tibial Nerve Mobilization in Patients With Tarsal Tunnel Syndrome Completed NCT05307354

Search NIH Clinical Center for Tarsal Tunnel Syndrome

Cochrane evidence based reviews: tarsal tunnel syndrome

Genetic Tests for Tarsal Tunnel Syndrome

Anatomical Context for Tarsal Tunnel Syndrome

Organs/tissues related to Tarsal Tunnel Syndrome:

MalaCards : Bone

Publications for Tarsal Tunnel Syndrome

Articles related to Tarsal Tunnel Syndrome:

(show top 50) (show all 612)
# Title Authors PMID Year
1
An update on imaging of tarsal tunnel syndrome. 62
35562562 2022
2
Magnetic Resonance Imaging Findings in Patients with Tarsal Tunnel Syndrome. 62
36184477 2022
3
Accessory slip of flexor digitorum accessorius (Quadratus plantae) muscle surrounding the lateral plantar nerve and vessels. 62
34247922 2022
4
Mid-term functional outcomes following reoperation after total ankle arthroplasty: A retrospective cohort study. 62
36088242 2022
5
How Common is Subsequent Posterior Tibial Tendon Dysfunction or Tarsal Tunnel Syndrome After Ankle Sprain Injury? 62
35944572 2022
6
Radiofrequency Plantar Fascia Coblation With and Without Gastrocnemius Recession in the Management of Recalcitrant Plantar Fasciitis. 62
35652744 2022
7
[Plantar Fasciopathy - Pathophysiology Diagnostics and Therapy - A Clinical Guideline]. 62
35983940 2022
8
Anatomy of the tibial nerve in relation to the tarsal tunnel: A cadaveric study. 62
35985969 2022
9
An Experience With an Exoscope System (ORBEYE) for Surgery for Tarsal Tunnel Syndrome: A Case Report. 62
36120253 2022
10
Retro-Malleolar Z-Plasty of Flexor Hallucis Longus Tendon in Post-Traumatic Checkrein Deformity: A Case Series and Literature Review. 62
36013539 2022
11
Predictive factors of effective tibial nerve release in tarsal tunnel syndrome. 62
34246562 2022
12
Acute Tarsal Tunnel Syndrome After Total Ankle Arthroplasty With Varus Deformity. 62
35821944 2022
13
[Clinical anatomical study on the treatment of tarsal tunnel syndrome with four-point vertical acupotomy]. 62
35730224 2022
14
An unusual cause of tarsal tunnel syndrome: Schwannoma of the posterior tibial nerve; a rare cause and rare localization. 62
35803099 2022
15
Tarsal Tunnel Syndrome: An Ultrasound Pictorial Review. 62
34342896 2022
16
Accessory Flexor Digitorum Longus Presenting as Tarsal Tunnel Syndrome: A Case Series. 62
35316824 2022
17
Tarsal tunnel syndrome secondary to accessory or variant muscles: a clinical and anatomical systematic review. 62
35353216 2022
18
Tarsal Tunnel Syndrome: Outcome According to Etiology. 62
34799273 2022
19
Avoidance of injury to the posterior neurovascular bundle during total ankle arthroplasty - A simple technical tip. 62
35581124 2022
20
A retrospective magnetic resonance imaging analysis of bone and soft tissue changes associated with the spectrum of tarsal coalitions. 62
35384073 2022
21
Patient reported outcomes following revision neurectomy through a dorsal approach for recurrent interdigital neuroma. 62
35393246 2022
22
Perioperative Complications and Adverse Events after Surgery for Peripheral Nerve- and Para-lumbar Spine Diseases. 62
34759069 2022
23
Calcaneal osteotomy for hindfoot deformity. 62
34687951 2022
24
Previously Unreported Case of Variant Posterior Tibial Vein Forming a Loop Adjacent to the Posterior Tibial Artery. 62
35340515 2022
25
The Course of Tarsal Tunnel Syndrome after Ultrasound-Guided Injections. 62
35769651 2022
26
[An unusual cause of tarsal tunnel syndrome in a 15-year-old girl: about a case]. 62
36034033 2022
27
Iatrogenic nerve injury and foot drop: Surgical results in 28 patients. 62
35855127 2022
28
Tarsal tunnel syndrome: Clinical-imaging analysis of a case series. 62
33947645 2022
29
An Update on Posterior Tarsal Tunnel Syndrome. 62
35769658 2022
30
A Rare Case of Flexor Digitorum Accessorius Longus Muscle Presenting as Tarsal Tunnel Syndrome. 62
35291249 2022
31
Clinical Results Following Conservative Management of Tarsal Tunnel Syndrome Compared With Surgical Treatment: A Systematic Review. 62
36072502 2022
32
Assessment of the frequency of tarsal tunnel syndrome in rheumatoid arthritis. 62
35141482 2021
33
Tarsal tunnel syndrome: current rationale, indications and results. 62
35839088 2021
34
Unusual bilateral variation of the flexor digitorum accessorius longus muscle and its relation on tarsal tunnel syndrome. 62
34559293 2021
35
Tarsal tunnel syndrome due to talocalcaneal coalition. 62
34607407 2021
36
Can the axial cross-sectional area of the tibial nerve be used to diagnose tarsal tunnel syndrome? An ultrasonography study. 62
32682728 2021
37
A Minimally Invasive Full Endoscopic Approach to Tibial Nerve Neurolysis in Diabetic Foot Neuropathy: An Alternative to Open Procedures. 62
34432688 2021
38
Carpal, cubital or tarsal tunnel syndrome after SARS-CoV-2 infection: A causal link? 62
34217126 2021
39
Stingray-Induced Tarsal Tunnel Syndrome. 62
34513381 2021
40
Narrative review of ring fixator management of recurrent club foot deformity. 62
34423016 2021
41
Ultrasound-Guided Near-Nerve Needle Sensory Technique for the Diagnosis of Tarsal Tunnel Syndrome. 62
34300231 2021
42
Endoscopic Ganglionectomy of the Tarsal Tunnel: A Medial Approach. 62
34258212 2021
43
Quantitative study of PIMT technique aiming its validation as physical therapy procedure. 62
33957521 2021
44
Mal-union of sustentaculum tali fracture with talo-calcaneal coalition leading to tarsal tunnel syndrome: A case report. 62
33964532 2021
45
Tarsal Tunnel Syndrome. 62
33745647 2021
46
Ultrasound-Guided Proximal and Distal Tarsal Decompression: An Analysis of Pressures in the Tarsal, Medial Plantar, and Lateral Plantar Tunnels. 62
32088990 2021
47
Variable Branching Pattern of Tibial Nerve in the Tarsal Tunnel: A Gross Anatomical Study With Clinical Implications. 62
33717767 2021
48
Tarsal tunnel syndrome in patients with fibromyalgia. 62
34046575 2021
49
Efficacy of a single botulinum toxin A injection for distal tarsal tunnel syndrome: A protocol for a randomized, double-blinded trial. 62
33553799 2021
50
Surgical efficacy analysis of tarsal tunnel syndrome: a retrospective study of 107 patients. 62
33106965 2021

Variations for Tarsal Tunnel Syndrome

Expression for Tarsal Tunnel Syndrome

Search GEO for disease gene expression data for Tarsal Tunnel Syndrome.

Pathways for Tarsal Tunnel Syndrome

GO Terms for Tarsal Tunnel Syndrome

Biological processes related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate phosphorylation GO:0046835 9.26 GNPTG GNPTAB
2 N-glycan processing to lysosome GO:0016256 8.92 GNPTG GNPTAB

Molecular functions related to Tarsal Tunnel Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity GO:0003976 8.92 GNPTG GNPTAB

Sources for Tarsal Tunnel Syndrome

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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